BRPI0815199A2 - Uso de um antígeno derivado da proteína circunsporozóite de plasmodium falciparum - Google Patents

Uso de um antígeno derivado da proteína circunsporozóite de plasmodium falciparum

Info

Publication number: BRPI0815199A2
Authority: BR; Brazil
Prior art keywords: circumsporozyte; protein; plasmodium falciparum; antigen derived; antigen
Prior art date: 2007-08-13

Application number

Other languages

English (en)

Inventor

William Ripley Ballou

Joseph D Cohen

Original Assignee

Glaxosmithkline Biolog Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-08-13

Filing date

2008-08-11

Publication date

2015-03-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39870250&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0815199(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-08-11 Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa

2015-03-31 Publication of BRPI0815199A2 publication Critical patent/BRPI0815199A2/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0016—Combination vaccines based on diphtheria-tetanus-pertussis
- A61K39/0017—Combination vaccines based on whole cell diphtheria-tetanus-pertussis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/116—Polyvalent bacterial antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6075—Viral proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Mycology (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Microbiology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Tropical Medicine & Parasitology (AREA)
Virology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)

BRPI0815199 2007-08-13 2008-08-11 Uso de um antígeno derivado da proteína circunsporozóite de plasmodium falciparum BRPI0815199A2 (pt)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US95544507P	2007-08-13	2007-08-13
US95733807P	2007-08-22	2007-08-22
US98280107P	2007-10-26	2007-10-26
PCT/EP2008/060505 WO2009021931A1 (en)	2007-08-13	2008-08-11	Vaccines

Publications (1)

Publication Number	Publication Date
BRPI0815199A2 true BRPI0815199A2 (pt)	2015-03-31

Family

ID=39870250

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0815199 BRPI0815199A2 (pt)	2007-08-13	2008-08-11	Uso de um antígeno derivado da proteína circunsporozóite de plasmodium falciparum

Country Status (21)

Country	Link
US (1)	US9066899B2 (pt)
EP (1)	EP2190470B1 (pt)
JP (1)	JP5508266B2 (pt)
KR (1)	KR20100068390A (pt)
AP (1)	AP2010005166A0 (pt)
AR (1)	AR067905A1 (pt)
AU (1)	AU2008288508B2 (pt)
BR (1)	BRPI0815199A2 (pt)
CA (1)	CA2695477A1 (pt)
CL (1)	CL2008002361A1 (pt)
CR (1)	CR11307A (pt)
DO (1)	DOP2010000056A (pt)
ES (1)	ES2658347T3 (pt)
MA (1)	MA31693B1 (pt)
MX (1)	MX2010001752A (pt)
NZ (1)	NZ583150A (pt)
TR (1)	TR201802221T4 (pt)
TW (1)	TW200924791A (pt)
UY (1)	UY31285A1 (pt)
WO (1)	WO2009021931A1 (pt)
ZA (1)	ZA201001029B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TR201802221T4 (tr)	2007-08-13	2018-03-21	Glaxosmithkline Biologicals Sa	Aşılar.
EP2818175B1 (en) *	2009-05-05	2018-11-21	Cadila Healthcare Limited	Combined measles-malaria vaccine
AU2010264686A1 (en)	2009-06-24	2012-01-19	Glaxosmithkline Biologicals S.A.	Vaccine
EP2451478A4 (en) *	2009-11-05	2013-11-20	Us Navy	PLASMODIUM FALCIPARUM SPOROZOITE AND LIVERPHASE ANTIGENS THEREWITH
EP2385107B1 (en) *	2010-05-03	2016-08-24	Institut Pasteur	Lentiviral vector based immunological compounds against malaria
EP2621540A4 (en) *	2010-09-27	2014-08-27	Univ Pennsylvania	CONSENSUS ANTIGEN CONSTRUCTS AND VACCINES MANUFACTURED THEREOF AND METHOD OF USE THEREOF FOR THE TREATMENT OF MALARIA
US20120244178A1 (en) *	2011-03-25	2012-09-27	Denise Doolan	Plasmodium falciparum antigens
CN102268093B (zh) *	2011-06-27	2013-06-26	广东药学院	一种肝靶向肽与人干扰素a2b融合蛋白及其制备方法和应用
US9169304B2 (en)	2012-05-01	2015-10-27	Pfenex Inc.	Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
GB201416773D0 (en) *	2014-09-23	2014-11-05	Glaxosmithkline Biolog S A And Chancellor Masters And Scolars Of The The University Of Oxford	Novel Methods For Including An Imune Response
WO2016184784A1 (en)	2015-05-15	2016-11-24	INSERM (Institut National de la Santé et de la Recherche Médicale)	Peptides including binding domain of plasmodium falciparum proteins (cbp1 and cbp2) to chemokine cx3cl1
CN113631573B (zh)	2019-03-25	2024-06-04	国家医疗保健研究所	抗Tau抗体及其在制备用于治疗疾病的药物中的用途

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4235877A (en) *	1979-06-27	1980-11-25	Merck & Co., Inc.	Liposome particle containing viral or bacterial antigenic subunit
US4372945A (en) *	1979-11-13	1983-02-08	Likhite Vilas V	Antigen compounds
IL61904A (en) *	1981-01-13	1985-07-31	Yeda Res & Dev	Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same
EP0071705B1 (en)	1981-05-21	1989-11-23	The Wellcome Foundation Limited	Protozoal antigen
US4436727A (en)	1982-05-26	1984-03-13	Ribi Immunochem Research, Inc.	Refined detoxified endotoxin product
CA1331443C (en)	1987-05-29	1994-08-16	Charlotte A. Kensil	Saponin adjuvant
US5057540A (en) *	1987-05-29	1991-10-15	Cambridge Biotech Corporation	Saponin adjuvant
US4912094B1 (en) *	1988-06-29	1994-02-15	Ribi Immunochem Research Inc.	Modified lipopolysaccharides and process of preparation
GB8819209D0 (en)	1988-08-12	1988-09-14	Research Corp Ltd	Polypeptide & dna encoding same
GB9002512D0 (en)	1990-02-05	1990-04-04	3I Res Expl Ltd	Polypeptides and dna encoding same
GB9012580D0 (en)	1990-06-06	1990-07-25	Univ Nijmegen	Novel protein
EP0468520A3 (en)	1990-07-27	1992-07-01	Mitsui Toatsu Chemicals, Inc.	Immunostimulatory remedies containing palindromic dna sequences
US5198535A (en)	1991-01-10	1993-03-30	The United States Of America As Represented By The Secretary Of The Navy	Protective malaria sporozoite surface protein immunogen and gene
ATE177755T1 (de)	1991-11-16	1999-04-15	Smithkline Beecham Biolog	Hybrides protein zwischen cs aus plasmodium und hbsag
JP3723231B2 (ja)	1991-12-23	2005-12-07	ディミナコアクチェンゲゼルシャフト	アジュバント
DK0671948T3 (da)	1992-06-25	1997-09-01	Smithkline Beecham Biolog	Vaccinepræparat indeholdende adjuvanser
ATE157882T1 (de)	1993-03-23	1997-09-15	Smithkline Beecham Biolog	3-0-deazylierte monophosphoryl lipid a enthaltende impfstoff-zusammensetzungen
GB9326253D0 (en)	1993-12-23	1994-02-23	Smithkline Beecham Biolog	Vaccines
ATE509102T1 (de)	1994-07-15	2011-05-15	Univ Iowa Res Found	Immunomodulatorische oligonukleotide
AUPM873294A0 (en)	1994-10-12	1994-11-03	Csl Limited	Saponin preparations and use thereof in iscoms
GB9620795D0 (en)	1996-10-05	1996-11-20	Smithkline Beecham Plc	Vaccines
UA56132C2 (uk)	1995-04-25	2003-05-15	Смітклайн Бічем Байолоджікалс С.А.	Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
GB9616351D0 (en)	1996-08-02	1996-09-11	Smithkline Beecham Biolog	Vaccine composition
WO1998010087A1 (en)	1996-09-06	1998-03-12	Trustees Of The University Of Pennsylvania	Chimpanzee adenovirus vectors
ES2241042T3 (es)	1996-10-11	2005-10-16	The Regents Of The University Of California	Conjugados de polinucleotido inmunoestimulador/ molecula inmunomoduladora.
CN1138578C (zh)	1997-03-29	2004-02-18	朴志勳	连续注射装置
GB9711990D0 (en)	1997-06-11	1997-08-06	Smithkline Beecham Biolog	Vaccine
US6645495B1 (en)	1997-08-29	2003-11-11	Antigenics, Inc.	Compositions of saponin adjuvants and excipients
GB9718901D0 (en)	1997-09-05	1997-11-12	Smithkline Beecham Biolog	Vaccine
ES2298316T3 (es)	1997-09-05	2008-05-16	Glaxosmithkline Biologicals S.A.	Emulsiones de aceite en agua que contienen saponinas.
AU2002306896B2 (en)	2001-03-26	2007-04-26	Walter Reed Army Institute Of Research	Plasmodium falciparum AMA-1 protein and uses thereof
US20030134404A1 (en)	2001-11-26	2003-07-17	Lochrie Michael A.	Methods for producing stocks of recombinant AAV virions
CA2502268A1 (en)	2002-10-23	2004-05-06	Glaxosmithkline Biologicals S.A.	Methods for vaccinating against malaria
WO2004044167A2 (en)	2002-11-12	2004-05-27	Walter Reed Army Institute Of Research	Expression, purification and uses of a plasmodium falciparum liver stage antigen 1 polypeptide
GB0420634D0 (en) *	2004-09-16	2004-10-20	Glaxosmithkline Biolog Sa	Vaccines
ES2371175T3 (es)	2004-10-14	2011-12-28	Crucell Holland B.V.	Vacunas de sensibilización/refuerzo de malaria.
GB0513421D0 (en)	2005-06-30	2005-08-03	Glaxosmithkline Biolog Sa	Vaccines
EP1754717A1 (en) *	2005-08-19	2007-02-21	Université de Lausanne	Antigenic peptides and their use
TR201802221T4 (tr)	2007-08-13	2018-03-21	Glaxosmithkline Biologicals Sa	Aşılar.
WO2014111733A1 (en) *	2013-01-21	2014-07-24	Isis Innovation Limited	Composition and uses thereof

2008
- 2008-08-11 TR TR2018/02221T patent/TR201802221T4/tr unknown
- 2008-08-11 MX MX2010001752A patent/MX2010001752A/es active IP Right Grant
- 2008-08-11 UY UY31285A patent/UY31285A1/es unknown
- 2008-08-11 BR BRPI0815199 patent/BRPI0815199A2/pt not_active Application Discontinuation
- 2008-08-11 AP AP2010005166A patent/AP2010005166A0/en unknown
- 2008-08-11 KR KR1020107005518A patent/KR20100068390A/ko not_active Abandoned
- 2008-08-11 AR ARP080103497A patent/AR067905A1/es not_active Application Discontinuation
- 2008-08-11 AU AU2008288508A patent/AU2008288508B2/en not_active Ceased
- 2008-08-11 EP EP08787080.4A patent/EP2190470B1/en active Active
- 2008-08-11 US US12/673,272 patent/US9066899B2/en active Active
- 2008-08-11 ES ES08787080.4T patent/ES2658347T3/es active Active
- 2008-08-11 CA CA2695477A patent/CA2695477A1/en active Pending
- 2008-08-11 TW TW097130604A patent/TW200924791A/zh unknown
- 2008-08-11 NZ NZ583150A patent/NZ583150A/en not_active IP Right Cessation
- 2008-08-11 JP JP2010520550A patent/JP5508266B2/ja active Active
- 2008-08-11 WO PCT/EP2008/060505 patent/WO2009021931A1/en not_active Ceased
- 2008-08-11 CL CL2008002361A patent/CL2008002361A1/es unknown
2010
- 2010-02-11 DO DO2010000056A patent/DOP2010000056A/es unknown
- 2010-02-11 ZA ZA2010/01029A patent/ZA201001029B/en unknown
- 2010-03-08 MA MA32675A patent/MA31693B1/fr unknown
- 2010-03-10 CR CR11307A patent/CR11307A/es unknown

Also Published As

Publication number	Publication date
ES2658347T3 (es)	2018-03-09
TR201802221T4 (tr)	2018-03-21
WO2009021931A1 (en)	2009-02-19
ZA201001029B (en)	2011-04-28
CN101820901A (zh)	2010-09-01
AU2008288508B2 (en)	2014-05-01
AP2010005166A0 (en)	2010-02-28
CA2695477A1 (en)	2009-02-19
KR20100068390A (ko)	2010-06-23
EP2190470A1 (en)	2010-06-02
MX2010001752A (es)	2010-03-10
CR11307A (es)	2010-05-24
TW200924791A (en)	2009-06-16
AR067905A1 (es)	2009-10-28
US20110212159A1 (en)	2011-09-01
UY31285A1 (es)	2009-03-31
EP2190470B1 (en)	2017-12-13
US9066899B2 (en)	2015-06-30
CL2008002361A1 (es)	2009-08-07
MA31693B1 (fr)	2010-09-01
AU2008288508A1 (en)	2009-02-19
JP2010535836A (ja)	2010-11-25
DOP2010000056A (es)	2010-07-31
JP5508266B2 (ja)	2014-05-28
NZ583150A (en)	2012-05-25

Publication	Publication Date	Title
BRPI0815199A2 (pt)	2015-03-31	Uso de um antígeno derivado da proteína circunsporozóite de plasmodium falciparum
CY2018003I1 (el)	2018-09-05	Ανθρωπινα αντισωματα υψηλης συγγενειας εναντιον ανθρωπινου υποδοχεα il-4
BRPI0717317A2 (pt)	2013-10-22	Modularoes da proteína cinase triazalopiridazina
SMT201600222B (it)	2016-08-31	Formulazione di anticorpi
BRPI0922708A2 (pt)	2018-11-06	peptídeos mini-hepcidina e métodos de uso do mesmo
PT2170388T (pt)	2017-01-04	Formulações de anticorpos anti-cd20
BRPI0912198A2 (pt)	2019-09-24	anticorpos anti-fn14 e usos dos mesmos
BRPI0914155A2 (pt)	2015-10-20	preparações de xampu
DK2041270T3 (da)	2014-01-27	Fremstilling af glycoproteiner
LT2351578T (lt)	2017-04-10	Vakcinų gavimo būdas
EP2207803A4 (en)	2010-11-24	Cd9-specific human antibodies
SMT201500186B (it)	2015-10-30	Autoanticorpi umani anti-alfa-sinucleina
BRPI0811637A2 (pt)	2014-11-18	Proteínas de fusão da imunoglobina
ITMI20061568A1 (it)	2008-02-04	Protesi di spalla
BRPI0819909A2 (pt)	2017-12-19	anticorpos antimesotelina e usos dos mesmos
EP2035014A4 (en)	2009-11-04	FUCOIDAN COMPOSITIONS AND METHOD
BRPI1014998A2 (pt)	2016-04-26	peptídio auxiliador de antígeno de câncer
IL265409A (en)	2019-05-30	Antibodies and processes for preparing the same
BRPI0914152A2 (pt)	2015-10-20	preparações de xampu
BRPI0913656A2 (pt)	2019-09-24	anticorpos anti-cdh3 marcados com marcador radioisótopo e usos dos mesmos
IL208979B (en)	2018-02-28	Humanized antibodies against human interferon-alpha
ITMI20042554A1 (it)	2005-03-30	Procedimento per la preparazione di dispersioni di fluoropolimeri
EP2084185A4 (en)	2010-11-17	HUMAN ANTIBODIES FOR NEUTRALIZING HUMAN METAPNEUMOVIRUS
BRPI0919485A2 (pt)	2015-12-01	vacinas, antígenos, composições de plasmodium e métodos
BRPI0921947A2 (pt)	2018-10-16	formulações de proteína terapêutica

Legal Events

Date	Code	Title	Description
2017-10-10	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2019-02-12	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]	Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI
2019-05-14	B06T	Formal requirements before examination [chapter 6.20 patent gazette]
2019-07-30	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2019-12-10	B09B	Patent application refused [chapter 9.2 patent gazette]
2020-03-03	B09B	Patent application refused [chapter 9.2 patent gazette]	Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL