BRPI0817154A2 - "método de modificar uma célula de levedura para a produção de etanol, célula de levedura modificada, uso de uma célula de levedura modificada e método para a produção de etanol" - Google Patents
"método de modificar uma célula de levedura para a produção de etanol, célula de levedura modificada, uso de uma célula de levedura modificada e método para a produção de etanol"Info
- Publication number
- BRPI0817154A2 BRPI0817154A2 BRPI0817154-8A2A BRPI0817154A BRPI0817154A2 BR PI0817154 A2 BRPI0817154 A2 BR PI0817154A2 BR PI0817154 A BRPI0817154 A BR PI0817154A BR PI0817154 A2 BRPI0817154 A2 BR PI0817154A2
- Authority
- BR
- Brazil
- Prior art keywords
- ethanol production
- year cell
- modified
- cell
- modifying
- Prior art date
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title 4
- 238000000034 method Methods 0.000 title 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01008—Glycerol-3-phosphate dehydrogenase (NAD+) (1.1.1.8)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/05—Oxidoreductases acting on the CH-OH group of donors (1.1) with a quinone or similar compound as acceptor (1.1.5)
- C12Y101/05003—Glycerol-3-phosphate dehydrogenase (1.1.5.3)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07021129A EP2060632A1 (en) | 2007-10-29 | 2007-10-29 | Method of modifying a yeast cell for the production of ethanol |
| PCT/IB2008/003672 WO2009056984A1 (en) | 2007-10-29 | 2008-10-29 | Method of modifying a yeast cell for the production of ethanol |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0817154A2 true BRPI0817154A2 (pt) | 2014-10-07 |
| BRPI0817154B1 BRPI0817154B1 (pt) | 2018-11-27 |
| BRPI0817154B8 BRPI0817154B8 (pt) | 2018-12-11 |
Family
ID=39048775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0817154A BRPI0817154B8 (pt) | 2007-10-29 | 2008-10-29 | "método de modificar uma célula de levedura para a produção de etanol, célula de levedura modificada, uso de uma célula de levedura modificada e método para a produção de etanol" |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US9175270B2 (pt) |
| EP (2) | EP2060632A1 (pt) |
| BR (1) | BRPI0817154B8 (pt) |
| CA (1) | CA2703856A1 (pt) |
| ES (1) | ES2521316T3 (pt) |
| WO (1) | WO2009056984A1 (pt) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| WO2008130995A2 (en) | 2007-04-18 | 2008-10-30 | E. I. Du Pont De Nemours And Company | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
| EP2594646A3 (en) | 2007-09-21 | 2013-11-06 | BASF Plant Science GmbH | Plant with increased yield |
| EP2060632A1 (en) * | 2007-10-29 | 2009-05-20 | Technische Universität Berlin | Method of modifying a yeast cell for the production of ethanol |
| EP2277989A1 (en) | 2009-07-24 | 2011-01-26 | Technische Universiteit Delft | Fermentative glycerol-free ethanol production |
| WO2011132890A2 (ko) * | 2010-04-19 | 2011-10-27 | 고려대학교 산학협력단 | 바이오 에탄올 생산 향상용 형질전환체 및 그 균주를 이용한 에탄올 생성방법 |
| US9605269B2 (en) * | 2010-05-05 | 2017-03-28 | Lallemand Hungary Liquidity Management Llc | Detoxification of biomass derived acetate via metabolic conversion to ethanol, acetone, isopropanol, or ethyl acetate |
| US9790521B2 (en) | 2011-03-24 | 2017-10-17 | Butamax Advanced Biofuels Llc | Host cells and methods for production of isobutanol |
| CN102329742B (zh) * | 2011-09-29 | 2014-06-11 | 浙江大学 | 一株适合浓醪发酵的酿酒酵母菌株及其应用 |
| CA2873109A1 (en) | 2012-05-11 | 2013-11-28 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
| BR112015006691A2 (pt) | 2012-09-26 | 2017-12-12 | Butamax Advanced Biofuels Llc | métodos, célula hospedeira recombinante, composição, polipeptídeo, polinucleotídeos e vetor recombinante |
| CN105378057A (zh) | 2013-03-14 | 2016-03-02 | 纳幕尔杜邦公司 | 用于丁醇生产的甘油3-磷酸脱氢酶 |
| CN105722969A (zh) | 2013-10-28 | 2016-06-29 | 丹尼斯科美国公司 | 大规模基因工程化活性干酵母 |
| WO2015148272A1 (en) | 2014-03-28 | 2015-10-01 | Danisco Us Inc. | Altered host cell pathway for improved ethanol production |
| EP3332004B1 (en) | 2015-08-05 | 2025-01-22 | Cargill, Incorporated | Xylose isomerase-modified yeast strains and methods for bioproduct production |
| WO2017189421A1 (en) | 2016-04-28 | 2017-11-02 | Danisco Us Inc. | Redox balancing in yeast |
| US20200407758A1 (en) * | 2016-07-01 | 2020-12-31 | Lallemand Hungary Liquidity Management Llc | Alpha-amylases for combination with glucoamylases for improving saccharification |
| US20190276905A1 (en) | 2016-11-09 | 2019-09-12 | Danisco Us Inc. | Yeast with improved alcohol production |
| EP3555295B1 (en) | 2016-12-16 | 2021-01-20 | Danisco US Inc. | Bifunctional phosphoketolase-phosphotransacetylase fusion polypeptides |
| BR112019014736A2 (pt) | 2017-01-18 | 2020-03-10 | Danisco Us Inc. | Células de levedura modificadas que superexpressam uma subunidade de adn polimerase |
| BR112019019701A2 (pt) | 2017-03-24 | 2020-07-14 | Danisco Us Inc. | redução de acetato e glicerol em levedura modificada que tem um caminho de produção de etanol exógeno |
| WO2018194892A1 (en) | 2017-04-17 | 2018-10-25 | Danisco Us Inc | Selected acetyl-coa synthase enzymes for reduction of acetate production in yeast |
| US12398362B2 (en) | 2017-06-06 | 2025-08-26 | Danisco Us Inc. | Yeast with improved alcohol production |
| JP6879111B2 (ja) * | 2017-08-02 | 2021-06-02 | トヨタ自動車株式会社 | 組換え酵母及びこれを用いたエタノールの製造方法 |
| UY37835A (es) | 2017-08-08 | 2019-03-29 | Danisco Us Inc | Producción incrementada de etanol por levaduras que albergan alelos del activador de transcripción constitutivo mal |
| EP3676288A1 (en) | 2017-08-29 | 2020-07-08 | Danisco US Inc. | Modified yeast comprising glucose-specific, atp-mediated transporters |
| BR112020008023A2 (pt) | 2017-10-24 | 2020-10-13 | Danisco Us Inc. | levedura com produção melhorada de álcool |
| ES2973502T3 (es) | 2018-03-06 | 2024-06-20 | Danisco Us Inc | Reducción en la producción de acetato por levadura que sobreexpresa pab1 |
| WO2019173225A1 (en) * | 2018-03-06 | 2019-09-12 | Danisco Us Inc | Yeast with improved alcohol production under high dissolved solids conditions |
| WO2019173217A1 (en) | 2018-03-06 | 2019-09-12 | Danisco Us Inc | Compositions and methods for increasing ethanol production by yeast using gcy1 and dak1 |
| US20210032642A1 (en) | 2018-04-06 | 2021-02-04 | Danisco Us Inc. | Increased alcohol production from yeast producing an increased amount of active hac1 protein |
| UY38179A (es) | 2018-04-12 | 2019-11-29 | Danisco Us Inc | Levadura que sobreexpresa proteína fosfatasas asociadas con la vía hog |
| KR102140596B1 (ko) | 2018-04-17 | 2020-08-04 | 에스케이이노베이션 주식회사 | 유기산 내성 효모 유래 신규 프로모터 및 이를 이용한 목적유전자의 발현방법 |
| CN118879519A (zh) | 2018-05-25 | 2024-11-01 | 丹尼斯科美国公司 | 富马酸还原酶过表达导致酵母中增加的发酵速率 |
| PT3802784T (pt) * | 2018-05-30 | 2024-10-31 | Danisco Us Inc | Sobreexpressão do ativador/repressor transcricional gis1 em levedura para aumento da produção de etanol |
| BR112021001577A2 (pt) | 2018-07-27 | 2021-04-20 | Danisco Us Inc. | produção de álcool aumentada a partir de levedura que produz uma quantidade aumentada de proteína crz1 ativa |
| US20210388397A1 (en) | 2018-09-28 | 2021-12-16 | Danisco Us Inc | Selected phosphotransacetylase genes for increased ethanol production in engineered yeast |
| WO2020069063A1 (en) | 2018-09-28 | 2020-04-02 | Danisco Us Inc | Over-expression of gds1 in yeast for increased ethanol and decreased acetate production |
| US20210395756A1 (en) | 2018-09-28 | 2021-12-23 | Danisco Us Inc | Over expression of ribonucleotide reductase inhibitor in yeast for increased ethanol production |
| KR102736070B1 (ko) | 2018-10-08 | 2024-12-02 | 에스케이이노베이션 주식회사 | 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법 |
| EP3908681A1 (en) | 2019-01-08 | 2021-11-17 | Danisco US Inc. | Hybrid yeast with increased ethanol production |
| EP3938519A1 (en) | 2019-03-14 | 2022-01-19 | Danisco US Inc. | Over-expression of fumarate-succinate transporter in yeast for increased ethanol and reduced acetate production |
| CN113795503A (zh) | 2019-03-14 | 2021-12-14 | 丹尼斯科美国公司 | 细胞色素b2在酵母中过表达用于增加乙醇生产 |
| BR112021021777A2 (pt) * | 2019-04-30 | 2022-02-08 | Univ Danmarks Tekniske | Métodos para a produção de ergotioneína |
| US12291713B2 (en) | 2019-06-24 | 2025-05-06 | Danisco Us Inc. | Modified yeast and method for increasing lysine content in fermentation co-products |
| WO2020263732A1 (en) | 2019-06-24 | 2020-12-30 | Danisco Us Inc | Disruption of cdc42 effectors in yeast for increased alcohol and lysine production |
| EP3990652A1 (en) | 2019-06-28 | 2022-05-04 | Danisco US Inc. | Modified yeast cells that over-express selected endogenous proteins |
| WO2021022140A1 (en) | 2019-08-01 | 2021-02-04 | Danisco Us Inc | Over-expression of pho13 for increased ethanol production by yeast |
| BR112022001859A2 (pt) | 2019-08-01 | 2022-06-28 | Danisco Us Inc | Superexpressão de adh5p para produção de etanol aumentada por levedura |
| EP4022076A1 (en) | 2019-08-29 | 2022-07-06 | Danisco US Inc. | Expression of beta-glucosidase in yeast for improved ethanol production |
| KR20210041903A (ko) | 2019-10-08 | 2021-04-16 | 에스케이이노베이션 주식회사 | 락테이트 대사 및 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법 |
| US20230002793A1 (en) | 2019-11-26 | 2023-01-05 | Danisco Us Inc | Reduction in acetate production by yeast over-expressing mig3 |
| WO2021150911A1 (en) | 2020-01-23 | 2021-07-29 | Danisco Us Inc | Increased ethanol production by overexpression of jid1 in yeast |
| KR20210128742A (ko) * | 2020-04-17 | 2021-10-27 | 에스케이이노베이션 주식회사 | 글리세롤 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법 |
| KR20210158676A (ko) | 2020-06-24 | 2021-12-31 | 에스케이이노베이션 주식회사 | 젖산 생산능이 증가된 재조합 내산성 효모 |
| CN117396608A (zh) | 2021-05-10 | 2024-01-12 | 丹尼斯科美国公司 | 通过在酵母中过表达kgd2增加乙醇生产 |
| BR112023025624A2 (pt) | 2021-06-07 | 2024-02-27 | Novozymes As | Célula de levedura recombinante, célula hospedeira recombinante, composição, cocultura, métodos de produção de um derivado de uma célula hospedeira recombinante e de produção de um produto de fermentação, e, uso de uma célula hospedeira recombinante |
| EP4423262A1 (en) | 2021-10-26 | 2024-09-04 | Danisco US Inc. | Reduction in acetate produced by yeast with reduced expression of rsf2 or tda9 |
| CN120712342A (zh) | 2022-12-05 | 2025-09-26 | 丹尼斯科美国公司 | 酵母在高溶解固体中增加乙醇生产 |
| CN121039276A (zh) | 2023-03-27 | 2025-11-28 | 丹尼斯科美国公司 | 使用表达来自帽铁形嘉利翁氏菌的RuBisCo的酵母减少发酵甘油和乙酸 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7018829B1 (en) * | 1998-07-10 | 2006-03-28 | Fluxome Sciences A/S | Metabolically engineered microbial cell with an altered metabolite production |
| GB0111275D0 (en) * | 2001-05-09 | 2001-06-27 | Secr Defence | Analytical method and kit |
| US7226735B2 (en) * | 2003-01-21 | 2007-06-05 | Wisconsin Alumni Research Foundation | Xylose-fermenting recombinant yeast strains |
| US7501275B2 (en) * | 2004-10-27 | 2009-03-10 | The United States Of America As Represented By The Secretary Of Agriculture | Yeast transformation system |
| US8110672B2 (en) * | 2005-04-27 | 2012-02-07 | Massachusetts Institute Of Technology | Promoter engineering and genetic control |
| CN101395282A (zh) * | 2006-01-03 | 2009-03-25 | 麻省理工学院 | 启动子改造与遗传控制 |
| BRPI0709607B1 (pt) * | 2006-03-13 | 2018-05-08 | Cargill Inc | cédulas de levedura tendo via rompida de diidroxi acetona fosfato para glicerol e processo de fermentação" |
| US7741119B2 (en) * | 2006-09-28 | 2010-06-22 | E. I. Du Pont De Nemours And Company | Xylitol synthesis mutant of xylose-utilizing zymomonas for ethanol production |
| DK2106447T3 (da) * | 2007-01-26 | 2013-06-24 | Novozymes As | Fremgangsmåde til methanoluafhængig induktion fra methanolinducerbare promotorer i Pichia |
| US20100159546A1 (en) * | 2007-03-30 | 2010-06-24 | Aristos Aristidou | Metabolic engineering of yeasts for the production of 1-butanol |
| EP2060632A1 (en) * | 2007-10-29 | 2009-05-20 | Technische Universität Berlin | Method of modifying a yeast cell for the production of ethanol |
| US20100291652A1 (en) * | 2008-08-06 | 2010-11-18 | Tianjin University | Yeast strains and methods of making and using such yeast strains |
-
2007
- 2007-10-29 EP EP07021129A patent/EP2060632A1/en not_active Ceased
-
2008
- 2008-10-29 CA CA2703856A patent/CA2703856A1/en not_active Abandoned
- 2008-10-29 WO PCT/IB2008/003672 patent/WO2009056984A1/en not_active Ceased
- 2008-10-29 ES ES08843807.2T patent/ES2521316T3/es active Active
- 2008-10-29 US US12/740,295 patent/US9175270B2/en active Active
- 2008-10-29 BR BRPI0817154A patent/BRPI0817154B8/pt active IP Right Grant
- 2008-10-29 EP EP08843807.2A patent/EP2222860B8/en active Active
-
2015
- 2015-09-16 US US14/856,308 patent/US20160153009A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2222860B1 (en) | 2014-05-07 |
| CA2703856A1 (en) | 2009-05-07 |
| WO2009056984A1 (en) | 2009-05-07 |
| BRPI0817154B1 (pt) | 2018-11-27 |
| ES2521316T3 (es) | 2014-11-12 |
| BRPI0817154B8 (pt) | 2018-12-11 |
| US20160153009A1 (en) | 2016-06-02 |
| EP2222860B8 (en) | 2015-09-02 |
| US9175270B2 (en) | 2015-11-03 |
| EP2060632A1 (en) | 2009-05-20 |
| EP2222860A1 (en) | 2010-09-01 |
| US20120295319A1 (en) | 2012-11-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06H | Technical and formal requirements: requirement cancelled [chapter 6.8 patent gazette] |
Free format text: A PRESENTE ANULACAO, SE REFERE AO DESPACHO 6.6, PUBLICADO NA RPI NO 2408 DE 01/03/2017. |
|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
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