BRPI0819328A8 - Compostos inibidores de replicação de vírus da imunodeficiência humana, composição farmacêutica e uso dos ditos compostos - Google Patents

Compostos inibidores de replicação de vírus da imunodeficiência humana, composição farmacêutica e uso dos ditos compostos

Info

Publication number
BRPI0819328A8
BRPI0819328A8 BRPI0819328A BRPI0819328A BRPI0819328A8 BR PI0819328 A8 BRPI0819328 A8 BR PI0819328A8 BR PI0819328 A BRPI0819328 A BR PI0819328A BR PI0819328 A BRPI0819328 A BR PI0819328A BR PI0819328 A8 BRPI0819328 A8 BR PI0819328A8
Authority
BR
Brazil
Prior art keywords
compounds
pharmaceutical composition
immunodeficiency virus
human immunodeficiency
virus replication
Prior art date
Application number
BRPI0819328A
Other languages
English (en)
Inventor
J Carson Rebekah
Fader Lee
Kawai Stephen
Landry Serge
S Tsantrizos Youla
Brochu Christian
Morin Sebastien
Parisien Mathieu
Simoneau Bruno
Original Assignee
Boehringer Ingelheim Int
Gilead Sciences Ltd
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int, Gilead Sciences Ltd, Gilead Sciences Inc filed Critical Boehringer Ingelheim Int
Publication of BRPI0819328A2 publication Critical patent/BRPI0819328A2/pt
Publication of BRPI0819328A8 publication Critical patent/BRPI0819328A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

COMPOSTOS INIBIDORES DE REPLICAÇÃO DE VÍRUS DA IMUNODEFICIÊNCIA HUMANA, COMPOSIÇÃO FARMACÊUTICA E USO DOS DITOS COMPOSTOS. A presente invenção refere-se a compostos de fórmula |:(1) em que c, X, Y, R2, R3, R4 e R6 são definidos aqui, que são úteis como inibidores de replicação de HIV.
BRPI0819328A 2007-11-15 2008-11-03 Compostos inibidores de replicação de vírus da imunodeficiência humana, composição farmacêutica e uso dos ditos compostos BRPI0819328A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98834207P 2007-11-15 2007-11-15
PCT/CA2008/001935 WO2009062288A1 (en) 2007-11-15 2008-11-03 Inhibitors of human immunodeficiency virus replication

Publications (2)

Publication Number Publication Date
BRPI0819328A2 BRPI0819328A2 (pt) 2015-05-12
BRPI0819328A8 true BRPI0819328A8 (pt) 2016-02-10

Family

ID=40638277

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0819328A BRPI0819328A8 (pt) 2007-11-15 2008-11-03 Compostos inibidores de replicação de vírus da imunodeficiência humana, composição farmacêutica e uso dos ditos compostos

Country Status (18)

Country Link
US (1) US7956068B2 (pt)
EP (2) EP2574610A1 (pt)
JP (1) JP5269085B2 (pt)
KR (1) KR20100108337A (pt)
CN (1) CN102124011A (pt)
AR (1) AR069334A1 (pt)
AU (1) AU2008323561B2 (pt)
BR (1) BRPI0819328A8 (pt)
CA (1) CA2705312C (pt)
CL (1) CL2008003405A1 (pt)
ES (1) ES2402322T3 (pt)
IL (1) IL205746A0 (pt)
MX (1) MX2010005292A (pt)
NZ (1) NZ585297A (pt)
RU (1) RU2503679C2 (pt)
TW (1) TW200920363A (pt)
WO (1) WO2009062288A1 (pt)
ZA (1) ZA201003305B (pt)

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US8633200B2 (en) 2010-09-08 2014-01-21 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
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JP6268656B2 (ja) 2013-03-14 2018-01-31 ビーブ・ヘルスケア・ユーケイ・（ナンバー５）・リミテッドＶｉｉＶ Ｈｅａｌｔｈｃａｒｅ ＵＫ （Ｎｏ．５） Ｌｉｍｉｔｅｄ ヒト免疫不全ウイルス複製の阻害剤
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EP3331868A1 (en) 2015-08-07 2018-06-13 VIIV Healthcare UK (No.5) Limited Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
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TWI657086B (zh) 2015-08-11 2019-04-21 英商Viiv醫療保健英國(No.5)有限公司 做為人類免疫缺陷病毒複製抑制劑之５－（ｎ－苯甲基四氫異喹啉－６－基）吡啶－３－基乙酸衍生物
KR20180032650A (ko) 2015-08-12 2018-03-30 비브 헬스케어 유케이 (넘버5) 리미티드 인간 면역결핍 바이러스 복제의 억제제로서 5-(n-[6,5]-융합된 바이사이클릭 아릴 테트라하이드로이소퀴놀린-6-일) 피리딘-3-일 아세트산 유도체
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TW201835068A (zh) 2017-01-03 2018-10-01 英商Viiv醫療保健英國(No.5)有限公司 作為人類免疫缺乏病毒複製之抑制劑之吡啶-3-基乙酸衍生物
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Also Published As

Publication number Publication date
BRPI0819328A2 (pt) 2015-05-12
CA2705312C (en) 2013-06-25
WO2009062288A1 (en) 2009-05-22
ES2402322T3 (es) 2013-04-30
IL205746A0 (en) 2010-11-30
US7956068B2 (en) 2011-06-07
CL2008003405A1 (es) 2010-02-12
CA2705312A1 (en) 2009-05-22
JP5269085B2 (ja) 2013-08-21
US20100305115A1 (en) 2010-12-02
EP2574610A1 (en) 2013-04-03
NZ585297A (en) 2012-06-29
AR069334A1 (es) 2010-01-13
RU2503679C2 (ru) 2014-01-10
ZA201003305B (en) 2011-03-30
TW200920363A (en) 2009-05-16
EP2220095A4 (en) 2011-01-26
RU2010123989A (ru) 2011-12-20
JP2011503117A (ja) 2011-01-27
MX2010005292A (es) 2010-07-05
EP2220095B1 (en) 2013-01-02
AU2008323561B2 (en) 2013-07-18
AU2008323561A1 (en) 2009-05-22
EP2220095A1 (en) 2010-08-25
KR20100108337A (ko) 2010-10-06
CN102124011A (zh) 2011-07-13

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