BRPI0819328A2 - Inibidores de replicação de vírus da imunodeficiência humana - Google Patents

Inibidores de replicação de vírus da imunodeficiência humana

Info

Publication number
BRPI0819328A2
BRPI0819328A2 BRPI0819328A BRPI0819328A2 BR PI0819328 A2 BRPI0819328 A2 BR PI0819328A2 BR PI0819328 A BRPI0819328 A BR PI0819328A BR PI0819328 A2 BRPI0819328 A2 BR PI0819328A2
Authority
BR
Brazil
Prior art keywords
immunodeficiency virus
human immunodeficiency
virus replication
replication inhibitors
inhibitors
Prior art date
Application number
Other languages
English (en)
Inventor
Rebekah J Carson
Lee Fader
Stephen Kawai
Serge Landry
Youla S Tsantrizos
Christian Brochu
Sebastien Morin
Mathieu Parisien
Bruno Simoneau
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of BRPI0819328A2 publication Critical patent/BRPI0819328A2/pt
Publication of BRPI0819328A8 publication Critical patent/BRPI0819328A8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0819328A 2007-11-15 2008-11-03 Compostos inibidores de replicação de vírus da imunodeficiência humana, composição farmacêutica e uso dos ditos compostos BRPI0819328A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98834207P 2007-11-15 2007-11-15
PCT/CA2008/001935 WO2009062288A1 (en) 2007-11-15 2008-11-03 Inhibitors of human immunodeficiency virus replication

Publications (2)

Publication Number Publication Date
BRPI0819328A2 true BRPI0819328A2 (pt) 2015-05-12
BRPI0819328A8 BRPI0819328A8 (pt) 2016-02-10

Family

ID=40638277

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0819328A BRPI0819328A8 (pt) 2007-11-15 2008-11-03 Compostos inibidores de replicação de vírus da imunodeficiência humana, composição farmacêutica e uso dos ditos compostos

Country Status (18)

Country Link
US (1) US7956068B2 (pt)
EP (2) EP2574610A1 (pt)
JP (1) JP5269085B2 (pt)
KR (1) KR20100108337A (pt)
CN (1) CN102124011A (pt)
AR (1) AR069334A1 (pt)
AU (1) AU2008323561B2 (pt)
BR (1) BRPI0819328A8 (pt)
CA (1) CA2705312C (pt)
CL (1) CL2008003405A1 (pt)
ES (1) ES2402322T3 (pt)
IL (1) IL205746A0 (pt)
MX (1) MX2010005292A (pt)
NZ (1) NZ585297A (pt)
RU (1) RU2503679C2 (pt)
TW (1) TW200920363A (pt)
WO (1) WO2009062288A1 (pt)
ZA (1) ZA201003305B (pt)

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US8633200B2 (en) 2010-09-08 2014-01-21 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
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EP2511273B8 (en) 2011-04-15 2019-06-26 Hivih Inhibitors of viral replication, their process of preparation and their therapeutical uses
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US8609653B2 (en) * 2011-07-15 2013-12-17 Glaxosmithkline Llc Azaindole compounds and methods for treating HIV
US8791108B2 (en) 2011-08-18 2014-07-29 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
US9199959B2 (en) 2011-10-25 2015-12-01 Shionogi & Co., Ltd. HIV replication inhibitor
HUE046795T2 (hu) * 2011-11-15 2020-03-30 St Pharm Co Ltd Új vírusellenes pirrolopiridin származékok és eljárás azok elõállítására
WO2013103738A1 (en) 2012-01-04 2013-07-11 Gilead Sciences, Inc. Napthalene acetic acid derivatives against hiv infection
US9376392B2 (en) 2012-01-04 2016-06-28 Gilead Sciences, Inc. 2-(tert-butoxy)-2-(7-methylquinolin-6-yl) acetic acid derivatives for treating AIDS
US8629276B2 (en) 2012-02-15 2014-01-14 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
US9034882B2 (en) * 2012-03-05 2015-05-19 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
US9006235B2 (en) 2012-03-06 2015-04-14 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
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PT2877468T (pt) * 2012-07-12 2017-11-21 Viiv Healthcare Uk Ltd Compostos e métodos para o tratamento de vih
US8906929B2 (en) * 2012-08-16 2014-12-09 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
EP2716632A1 (en) 2012-10-05 2014-04-09 Laboratoire Biodim Inhibitors of viral replication, their process of preparation and their therapeutical uses
EP2716639A1 (en) 2012-10-05 2014-04-09 Laboratoire Biodim Inhibitors of viral replication, their process of preparation and their therapeutical uses
EP2719685A1 (en) 2012-10-11 2014-04-16 Laboratoire Biodim Inhibitors of viral replication, their process of preparation and their therapeutical uses
TW201441197A (zh) 2013-01-31 2014-11-01 Shionogi & Co Hiv複製抑制劑
ES2619708T3 (es) 2013-03-13 2017-06-26 VIIV Healthcare UK (No.5) Limited Inhibidores de la replicación del virus de inmunodeficiencia humana
EP2970298A1 (en) 2013-03-13 2016-01-20 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
JP2016512507A (ja) 2013-03-13 2016-04-28 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company ヒト免疫不全ウイルス複製の阻害剤
CN105008369B (zh) 2013-03-14 2017-07-11 百时美施贵宝公司 人类免疫缺陷病毒复制抑制剂
WO2014159959A1 (en) 2013-03-14 2014-10-02 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
EP3008073B1 (en) 2013-06-11 2020-01-01 Latvian Institute Of Organic Synthesis Thieno[2,3-b]pyridines as multidrug resistance modulators
EP2821104A1 (en) 2013-07-05 2015-01-07 Laboratoire Biodim Inhibitors of viral replication, their process of preparation and their therapeutical uses
EP2821082A1 (en) 2013-07-05 2015-01-07 Laboratoire Biodim Method of producing an inactivated lentivirus, especially HIV, vaccine, kit and method of use
ES2654242T3 (es) 2014-02-12 2018-02-12 Viiv Healthcare (No.5) Limited Macrociclos de benzotiazol como inhibidores de la réplica del virus de la inmunodeficiencia humana
EP3116879A1 (en) 2014-02-18 2017-01-18 VIIV Healthcare UK (No.5) Limited Imidazopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication
US9409922B2 (en) 2014-02-18 2016-08-09 Bristol-Myers Squibb Company Imidazopyridine macrocycles as inhibitors of human immunodeficiency virus replication
EP3152215A1 (en) 2014-02-18 2017-04-12 ViiV Healthcare UK (No.5) Limited Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication
WO2015126765A1 (en) 2014-02-19 2015-08-27 Bristol-Myers Squibb Company Inhibitors of human immunodeficiency virus replication
US9273067B2 (en) 2014-02-19 2016-03-01 Bristol-Myers Squibb Company Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication
ES2670010T3 (es) 2014-02-20 2018-05-29 VIIV Healthcare UK (No.5) Limited Macrociclos de ácido piridin-3-il acético como inhibidores de replicación del virus de inmunodeficiencia humana
US9193720B2 (en) 2014-02-20 2015-11-24 Bristol-Myers Squibb Company Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
WO2015174511A1 (ja) 2014-05-16 2015-11-19 塩野義製薬株式会社 Hiv複製阻害作用を有する3環性複素環誘導体
SG11201709634QA (en) 2015-05-29 2017-12-28 Shionogi & Co Nitrogen-containing tricyclic derivative having hiv replication inhibitory activity
US20180170903A1 (en) 2015-07-06 2018-06-21 VIIV Healthcare UK (No.5) Limited Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
EP3319957A1 (en) 2015-07-08 2018-05-16 VIIV Healthcare UK (No.5) Limited Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
RU2018103031A (ru) 2015-07-09 2019-08-09 ВАЙВ ХЕЛТКЕР ЮКей (N5) ЛИМИТЕД Производные пиридин-3-ил уксусной кислоты в качестве ингибиторов репликации вируса иммунодефицита человека
AU2016290986A1 (en) 2015-07-09 2018-01-18 VIIV Healthcare UK (No.5) Limited Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
KR20180035910A (ko) 2015-08-07 2018-04-06 비브 헬스케어 유케이 (넘버5) 리미티드 인간 면역결핍 바이러스 복제의 억제제로서 피리딘-3-일 아세트산 유도체
CN108026113A (zh) 2015-08-10 2018-05-11 Viiv保健英国第五有限公司 作为人免疫缺陷病毒复制的抑制剂的咪唑并吡啶大环类化合物
TWI657086B (zh) 2015-08-11 2019-04-21 英商Viiv醫療保健英國(No.5)有限公司 做為人類免疫缺陷病毒複製抑制劑之5-(n-苯甲基四氫異喹啉-6-基)吡啶-3-基乙酸衍生物
TW201718537A (zh) 2015-08-12 2017-06-01 Viiv醫療保健英國(No.5)有限公司 做為人類免疫缺陷病毒複製抑制劑之吡啶-3-基乙酸衍生物
CA2995087A1 (en) 2015-08-12 2017-02-16 John F. Kadow 5-(n-fused tricyclic aryl tetrahydroisoquinolin-6-yl) pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
CN108137553A (zh) 2015-08-12 2018-06-08 Viiv保健英国第五有限公司 作为人免疫缺陷病毒复制的抑制剂的5-(n-[6,5]-稠合双环芳基四氢异喹啉-6-基)吡啶-3-基乙酸衍生物
US10106504B2 (en) * 2015-08-20 2018-10-23 VIIV Healthcare UK (No.5) Limited Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
WO2017195112A1 (en) 2016-05-11 2017-11-16 VIIV Healthcare UK (No.5) Limited Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
JP2019515939A (ja) 2016-05-11 2019-06-13 ヴィーブ ヘルスケア ユーケー(ナンバー5)リミテッド ヒト免疫不全ウイルス複製の阻害剤としてのピリジン−3−イル酢酸誘導体
US10407410B2 (en) 2016-05-11 2019-09-10 VIIV Healthcare UK (No.5) Limited Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
KR102430610B1 (ko) * 2016-08-12 2022-08-08 바이엘 크롭사이언스 악티엔게젤샤프트 치환된 스티렌 유도체의 제조 방법
US20200055839A1 (en) 2017-01-03 2020-02-20 VIIV Healthcare UK (No.5) Limited Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
US20200016136A1 (en) 2017-01-03 2020-01-16 Viiv Healthcare Uk (No. 5) Limited Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
WO2019244066A2 (en) 2018-06-19 2019-12-26 VIIV Healthcare UK (No.5) Limited Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
WO2020003093A1 (en) 2018-06-25 2020-01-02 VIIV Healthcare UK (No.5) Limited Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication
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WO2020168927A1 (zh) * 2019-02-19 2020-08-27 四川科伦博泰生物医药股份有限公司 含氮并环化合物、其制备方法及用途
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Also Published As

Publication number Publication date
EP2220095B1 (en) 2013-01-02
BRPI0819328A8 (pt) 2016-02-10
AU2008323561B2 (en) 2013-07-18
TW200920363A (en) 2009-05-16
CA2705312C (en) 2013-06-25
US20100305115A1 (en) 2010-12-02
EP2574610A1 (en) 2013-04-03
IL205746A0 (en) 2010-11-30
CA2705312A1 (en) 2009-05-22
JP2011503117A (ja) 2011-01-27
AU2008323561A1 (en) 2009-05-22
ZA201003305B (en) 2011-03-30
CN102124011A (zh) 2011-07-13
CL2008003405A1 (es) 2010-02-12
WO2009062288A1 (en) 2009-05-22
ES2402322T3 (es) 2013-04-30
RU2503679C2 (ru) 2014-01-10
RU2010123989A (ru) 2011-12-20
NZ585297A (en) 2012-06-29
AR069334A1 (es) 2010-01-13
EP2220095A1 (en) 2010-08-25
MX2010005292A (es) 2010-07-05
JP5269085B2 (ja) 2013-08-21
US7956068B2 (en) 2011-06-07
EP2220095A4 (en) 2011-01-26
KR20100108337A (ko) 2010-10-06

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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Owner name: GILEAD SCIENCES LIMITED (IE)

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.