BRPI0819828A2 - Processo de síntese de oligômeros de morfolino. - Google Patents

Processo de síntese de oligômeros de morfolino.

Info

Publication number
BRPI0819828A2
BRPI0819828A2 BRPI0819828-4A BRPI0819828A BRPI0819828A2 BR PI0819828 A2 BRPI0819828 A2 BR PI0819828A2 BR PI0819828 A BRPI0819828 A BR PI0819828A BR PI0819828 A2 BRPI0819828 A2 BR PI0819828A2
Authority
BR
Brazil
Prior art keywords
synthesis
morpholino oligomers
morpholino
oligomers
Prior art date
Application number
BRPI0819828-4A
Other languages
English (en)
Inventor
Christina Mary Josephine Fox
Matthew Dale Reeves
Dwight D Weller
Yongfu Li
Original Assignee
Avi Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avi Biopharma Inc filed Critical Avi Biopharma Inc
Publication of BRPI0819828A2 publication Critical patent/BRPI0819828A2/pt
Publication of BRPI0819828A8 publication Critical patent/BRPI0819828A8/pt
Publication of BRPI0819828B1 publication Critical patent/BRPI0819828B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BRPI0819828-4A 2007-11-15 2008-11-14 Compostos de morfolino e processos para sintetizar um oligômero de morfolino BRPI0819828B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US98819207P 2007-11-15 2007-11-15
US98820007P 2007-11-15 2007-11-15
US60/988.192 2007-11-15
US60/988.200 2007-11-15
PCT/US2008/012804 WO2009064471A1 (en) 2007-11-15 2008-11-14 Method of synthesis of morpholino oligomers

Publications (3)

Publication Number Publication Date
BRPI0819828A2 true BRPI0819828A2 (pt) 2015-05-26
BRPI0819828A8 BRPI0819828A8 (pt) 2022-12-27
BRPI0819828B1 BRPI0819828B1 (pt) 2025-09-09

Family

ID=

Also Published As

Publication number Publication date
KR20100090681A (ko) 2010-08-16
WO2009064471A1 (en) 2009-05-22
CA2704261A1 (en) 2009-05-22
JP2014159432A (ja) 2014-09-04
JP6178744B2 (ja) 2017-08-09
DK2207779T3 (da) 2014-07-14
ES2479393T3 (es) 2014-07-24
CA2884340A1 (en) 2009-05-22
CN101861318A (zh) 2010-10-13
RU2606627C2 (ru) 2017-01-10
BRPI0819828A8 (pt) 2022-12-27
CA2704261C (en) 2015-05-26
AU2008321409A1 (en) 2009-05-22
BR122019021332A8 (pt) 2022-12-06
RU2010123958A (ru) 2011-12-20
JP5512533B2 (ja) 2014-06-04
JP2011503184A (ja) 2011-01-27
CA2884340C (en) 2017-07-25
KR101617472B1 (ko) 2016-05-02
EP2207779B1 (en) 2014-04-09
HK1144424A1 (en) 2011-02-18
MX2010004955A (es) 2010-06-30
JP2016196494A (ja) 2016-11-24
HRP20140646T1 (hr) 2014-09-26
BR122019021332A2 (pt) 2015-05-26
IL205776A0 (en) 2010-11-30
AU2008321409B2 (en) 2014-08-14
EP2207779A1 (en) 2010-07-21

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B25D Requested change of name of applicant approved

Owner name: SAREPTA THERAPEUTICS, INC. (US)

B25G Requested change of headquarter approved

Owner name: SAREPTA THERAPEUTICS, INC. (US)

B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/11/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.