DK2207779T3 - Fremgangsmåde til syntese af morpholinooligomerer - Google Patents

Fremgangsmåde til syntese af morpholinooligomerer

Info

Publication number
DK2207779T3
DK2207779T3 DK08850132.5T DK08850132T DK2207779T3 DK 2207779 T3 DK2207779 T3 DK 2207779T3 DK 08850132 T DK08850132 T DK 08850132T DK 2207779 T3 DK2207779 T3 DK 2207779T3
Authority
DK
Denmark
Prior art keywords
synthesis
morpholine oligomers
morpholine
oligomers
Prior art date
Application number
DK08850132.5T
Other languages
English (en)
Inventor
Yongfu Li
Christina Mary Josephine Fox
Matthew Dale Reeves
Dwight D Weller
Original Assignee
Sarepta Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sarepta Therapeutics Inc filed Critical Sarepta Therapeutics Inc
Application granted granted Critical
Publication of DK2207779T3 publication Critical patent/DK2207779T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK08850132.5T 2007-11-15 2008-11-14 Fremgangsmåde til syntese af morpholinooligomerer DK2207779T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98820007P 2007-11-15 2007-11-15
US98819207P 2007-11-15 2007-11-15
PCT/US2008/012804 WO2009064471A1 (en) 2007-11-15 2008-11-14 Method of synthesis of morpholino oligomers

Publications (1)

Publication Number Publication Date
DK2207779T3 true DK2207779T3 (da) 2014-07-14

Family

ID=40293764

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08850132.5T DK2207779T3 (da) 2007-11-15 2008-11-14 Fremgangsmåde til syntese af morpholinooligomerer

Country Status (13)

Country Link
EP (1) EP2207779B1 (da)
JP (3) JP5512533B2 (da)
KR (1) KR101617472B1 (da)
CN (1) CN101861318A (da)
BR (1) BR122019021332A8 (da)
CA (2) CA2704261C (da)
DK (1) DK2207779T3 (da)
ES (1) ES2479393T3 (da)
HR (1) HRP20140646T1 (da)
IL (1) IL205776A0 (da)
MX (1) MX2010004955A (da)
RU (1) RU2606627C2 (da)
WO (1) WO2009064471A1 (da)

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Also Published As

Publication number Publication date
CA2884340A1 (en) 2009-05-22
BRPI0819828A8 (pt) 2022-12-27
JP2011503184A (ja) 2011-01-27
RU2010123958A (ru) 2011-12-20
AU2008321409B2 (en) 2014-08-14
CN101861318A (zh) 2010-10-13
BR122019021332A8 (pt) 2022-12-06
CA2884340C (en) 2017-07-25
JP5512533B2 (ja) 2014-06-04
JP2014159432A (ja) 2014-09-04
MX2010004955A (es) 2010-06-30
KR101617472B1 (ko) 2016-05-02
CA2704261C (en) 2015-05-26
CA2704261A1 (en) 2009-05-22
BRPI0819828A2 (pt) 2015-05-26
AU2008321409A1 (en) 2009-05-22
HRP20140646T1 (hr) 2014-09-26
HK1144424A1 (en) 2011-02-18
BR122019021332A2 (da) 2015-05-26
JP2016196494A (ja) 2016-11-24
RU2606627C2 (ru) 2017-01-10
KR20100090681A (ko) 2010-08-16
JP6178744B2 (ja) 2017-08-09
EP2207779B1 (en) 2014-04-09
EP2207779A1 (en) 2010-07-21
WO2009064471A1 (en) 2009-05-22
ES2479393T3 (es) 2014-07-24
IL205776A0 (en) 2010-11-30

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