BRPI0820343A2 - Anticorpos de antifator b e seus usos - Google Patents
Anticorpos de antifator b e seus usosInfo
- Publication number
- BRPI0820343A2 BRPI0820343A2 BRPI0820343A BRPI0820343A BRPI0820343A2 BR PI0820343 A2 BRPI0820343 A2 BR PI0820343A2 BR PI0820343 A BRPI0820343 A BR PI0820343A BR PI0820343 A BRPI0820343 A BR PI0820343A BR PI0820343 A2 BRPI0820343 A2 BR PI0820343A2
- Authority
- BR
- Brazil
- Prior art keywords
- antibodies
- factor
- antifactor
- cnv
- amd
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
ANTICORPOS DE ANTIFATOR B E SEUS USOS. A invenção refere-se à prevenção e tratamento de condição de olho associada a complementos, tais como neovascularização da coroide (CNV) e degeneração macular relacionada à idade (AMD), por administração de antagonistas de fator B.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US264807P | 2007-11-08 | 2007-11-08 | |
| PCT/US2008/082621 WO2009061910A1 (en) | 2007-11-08 | 2008-11-06 | Anti-factor b antibodies and their uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0820343A2 true BRPI0820343A2 (pt) | 2017-08-22 |
Family
ID=40344464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0820343A BRPI0820343A2 (pt) | 2007-11-08 | 2008-11-06 | Anticorpos de antifator b e seus usos |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US8158762B2 (pt) |
| EP (1) | EP2209807A1 (pt) |
| JP (1) | JP2011503094A (pt) |
| KR (1) | KR20100105587A (pt) |
| CN (1) | CN101918444A (pt) |
| AR (1) | AR069233A1 (pt) |
| AU (1) | AU2008323939A1 (pt) |
| BR (1) | BRPI0820343A2 (pt) |
| CA (1) | CA2704973A1 (pt) |
| CL (1) | CL2008003313A1 (pt) |
| IL (1) | IL205577A0 (pt) |
| MX (1) | MX2010005115A (pt) |
| PE (1) | PE20091022A1 (pt) |
| TW (1) | TW200927170A (pt) |
| WO (1) | WO2009061910A1 (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS20120461A1 (sr) | 2009-07-02 | 2013-06-28 | Musc Foundation For Research Development | Metode za stimulaciju regeneracije jetre |
| TWI407953B (zh) * | 2011-03-24 | 2013-09-11 | Univ Kaohsiung Medical | 用於調節補體因子b(cfb)表現的醫藥組合物 |
| WO2013177035A2 (en) * | 2012-05-24 | 2013-11-28 | Alexion Pharmaceuticals, Inc. | Humaneered anti-factor b antibody |
| KR102495018B1 (ko) | 2013-11-15 | 2023-02-06 | 아케비아 테라퓨틱스 인코포레이티드 | {[5-(3-클로로페닐)-3-하이드록시피리딘-2-카보닐]아미노}아세트산의 고체형, 이의 조성물 및 용도 |
| US10934347B2 (en) * | 2016-04-04 | 2021-03-02 | Genzyme Corporation | Anti-complement factor BB antibodies and uses thereof |
| US11524939B2 (en) | 2019-11-13 | 2022-12-13 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid |
| WO2021216458A1 (en) | 2020-04-20 | 2021-10-28 | Genzyme Corporation | Humanized anti-complement factor bb antibodies and uses thereof |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4873191A (en) | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
| NZ201705A (en) | 1981-08-31 | 1986-03-14 | Genentech Inc | Recombinant dna method for production of hepatitis b surface antigen in yeast |
| DD266710A3 (de) | 1983-06-06 | 1989-04-12 | Ve Forschungszentrum Biotechnologie | Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase |
| US4736866A (en) | 1984-06-22 | 1988-04-12 | President And Fellows Of Harvard College | Transgenic non-human mammals |
| US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
| GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| GB8610600D0 (en) | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
| WO1989006692A1 (en) | 1988-01-12 | 1989-07-27 | Genentech, Inc. | Method of treating tumor cells by inhibiting growth factor receptor function |
| DE68925971T2 (de) | 1988-09-23 | 1996-09-05 | Cetus Oncology Corp | Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte |
| FR2646437B1 (fr) | 1989-04-28 | 1991-08-30 | Transgene Sa | Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant |
| EP0402226A1 (en) | 1989-06-06 | 1990-12-12 | Institut National De La Recherche Agronomique | Transformation vectors for yeast yarrowia |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| JPH07501451A (ja) | 1991-11-25 | 1995-02-16 | エンゾン・インコーポレイテッド | 多価抗原結合タンパク質 |
| EP1005870B1 (en) | 1992-11-13 | 2009-01-21 | Biogen Idec Inc. | Therapeutic application of chimeric antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
| JP4753578B2 (ja) | 2002-06-03 | 2011-08-24 | ジェネンテック, インコーポレイテッド | 合成抗体ファージライブラリー |
| US20070123466A1 (en) * | 2003-05-13 | 2007-05-31 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Method of treating recurrent miscarriages |
| BRPI0506629A (pt) * | 2004-02-10 | 2007-05-02 | Univ Colorado | inibição do fator b, a via alternativa do sistema complemento e métodos relacionados |
| HUE026423T2 (en) * | 2005-11-04 | 2016-05-30 | Genentech Inc | Use of complement biosynthetic pathway inhibitors for treating eye diseases |
| CA3009846C (en) * | 2006-03-08 | 2021-08-31 | David Epstein | Complement binding aptamers and anti-c5 agents useful in the treatment of ocular disorders |
| US20100120665A1 (en) * | 2007-03-01 | 2010-05-13 | Advanced Vision Therapies, Inc. | Treatment of diseases characterized by inflammation |
-
2008
- 2008-11-06 BR BRPI0820343A patent/BRPI0820343A2/pt not_active IP Right Cessation
- 2008-11-06 EP EP08848036A patent/EP2209807A1/en not_active Withdrawn
- 2008-11-06 US US12/291,222 patent/US8158762B2/en not_active Expired - Fee Related
- 2008-11-06 AU AU2008323939A patent/AU2008323939A1/en not_active Abandoned
- 2008-11-06 MX MX2010005115A patent/MX2010005115A/es unknown
- 2008-11-06 CN CN2008801243361A patent/CN101918444A/zh active Pending
- 2008-11-06 KR KR1020107012466A patent/KR20100105587A/ko not_active Withdrawn
- 2008-11-06 JP JP2010533241A patent/JP2011503094A/ja active Pending
- 2008-11-06 WO PCT/US2008/082621 patent/WO2009061910A1/en not_active Ceased
- 2008-11-06 CA CA2704973A patent/CA2704973A1/en not_active Abandoned
- 2008-11-07 CL CL2008003313A patent/CL2008003313A1/es unknown
- 2008-11-07 AR ARP080104888A patent/AR069233A1/es not_active Application Discontinuation
- 2008-11-07 PE PE2008001904A patent/PE20091022A1/es not_active Application Discontinuation
- 2008-11-07 TW TW097143224A patent/TW200927170A/zh unknown
-
2010
- 2010-05-06 IL IL205577A patent/IL205577A0/en unknown
-
2012
- 2012-01-31 US US13/385,057 patent/US20120230997A1/en not_active Abandoned
-
2015
- 2015-10-06 US US14/876,655 patent/US20160024224A1/en not_active Abandoned
-
2017
- 2017-10-23 US US15/791,064 patent/US20180037667A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2209807A1 (en) | 2010-07-28 |
| US20180037667A1 (en) | 2018-02-08 |
| CN101918444A (zh) | 2010-12-15 |
| MX2010005115A (es) | 2010-05-27 |
| WO2009061910A1 (en) | 2009-05-14 |
| AR069233A1 (es) | 2010-01-06 |
| US20160024224A1 (en) | 2016-01-28 |
| TW200927170A (en) | 2009-07-01 |
| CL2008003313A1 (es) | 2010-02-05 |
| AU2008323939A1 (en) | 2009-05-14 |
| IL205577A0 (en) | 2010-11-30 |
| US20090123469A1 (en) | 2009-05-14 |
| US20120230997A1 (en) | 2012-09-13 |
| KR20100105587A (ko) | 2010-09-29 |
| US8158762B2 (en) | 2012-04-17 |
| PE20091022A1 (es) | 2009-07-16 |
| JP2011503094A (ja) | 2011-01-27 |
| CA2704973A1 (en) | 2009-05-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1116062T1 (el) | Προληπτικη και θεραπευτικη αγωγη οφθαλμικων παθησεων σχετιζομενων με συμπληρωμα | |
| BRPI0820343A2 (pt) | Anticorpos de antifator b e seus usos | |
| MX2021011394A (es) | Compuestos de carbamoilpiridona triciclica puenteada y su uso farmaceutico. | |
| WO2012100142A3 (en) | Treatments for retinal disorders | |
| EA201892431A1 (ru) | Олигонуклеотиды для лечения заболевания глаз | |
| CL2017001191A1 (es) | Compuestos derivados de carbamoilpiridona policíclicos; composición farmacéutica que los comprende; y su uso para el tratamiento de una infección de vih en un humano que tiene o se encuentra en riesgo de tener la infección. | |
| PH12013501436A1 (en) | Indole compounds or analogues thereof useful for the treatment of age-related macular degeneration (amd) | |
| CY1119766T1 (el) | Νεοι ρυθμιστες κινασης βενζοπυρανιου | |
| NI201900085A (es) | 2-heteroaril-3-oxo-2,3-dihidropiridazin-4-carboxamidas | |
| ECSP12011692A (es) | Derivados de oxazina y su uso en el tratamiento de los trastornos neurológicos | |
| CY1118452T1 (el) | Ενωσεις και συνθεσεις ως αναστολεις πρωτεϊνικης κινασης | |
| BRPI0808775A2 (pt) | compostos e composições como moduladores de atividade de gpr119 | |
| MY171920A (en) | Prevention and treatment of ocular conditions | |
| CY1116424T1 (el) | Παραγωγο αδενινης ως αναστολεας ρι3κ | |
| EA201290498A1 (ru) | Терапевтические полимерные наночастицы, включающие эпотилон, и способы их получения и применения | |
| WO2009097468A3 (en) | Drug delivery devices, kits and methods therefor | |
| BR112014008759A2 (pt) | tratamento de doença ocular | |
| WO2007133800A3 (en) | Toll-like receptor (tlr) stimulation for ocular angiogenesis and macular degeneration | |
| MX2015012435A (es) | Derivados de 3-fenilpropilamina sustituidos para el tratamiento de enfermedades y trastornos oftalmicos. | |
| MX2019008963A (es) | Composicion para la prevencion o el tratamiento de deterioros visuales que comprenden acido ursodesoxicolico. | |
| ECSP11010956A (es) | Compuestos enlazados con azufre para el tratamiento de enfermedades y trastornos oftalmicos | |
| CR20110294A (es) | Piperidina espiro pirrolidinona y piperidinona sustituidas, su preparación y su uso terapéutico | |
| BR112017021083A2 (pt) | piridopirimidinonas e seu uso como moduladores do receptor de nmda | |
| MY184647A (en) | Arylated camphenes, processes for their preparation and uses thereof | |
| CR20110289A (es) | Tetrahidropiran espiro pirrolidinona y piperidinona sustituidas, su preparación y su uso terapéutico |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B15I | Others concerning applications: loss of priority | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2435 DE 05-09-2017 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |