BRPI0821301A2 - Composto de aspirinato de isossorbida, composto carregador, composto medicamentoso, composição farmacêutica, e, uso de um composto - Google Patents

Composto de aspirinato de isossorbida, composto carregador, composto medicamentoso, composição farmacêutica, e, uso de um composto

Info

Publication number: BRPI0821301A2
Authority: BR; Brazil
Prior art keywords: compound; pharmaceutical composition; carrier; drug; isosorbide
Prior art date: 2007-12-21

Application number

BRPI0821301-1A

Other languages

English (en)

Inventor

John Francis Gilmer

Louise Clune-Moriarty

Maeve Lally

Original Assignee

Trinity College Dublin

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-12-21

Filing date

2008-12-19

Publication date

2015-06-16

2008-12-19 Application filed by Trinity College Dublin filed Critical Trinity College Dublin

2015-06-16 Publication of BRPI0821301A2 publication Critical patent/BRPI0821301A2/pt

2019-05-21 Publication of BRPI0821301B1 publication Critical patent/BRPI0821301B1/pt

2019-06-04 Publication of BRPI0821301B8 publication Critical patent/BRPI0821301B8/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Medicinal Preparation (AREA)

BRPI0821301A 2007-12-21 2008-12-19 composto de aspirinato de isossorbida, composição farmacêutica, e, seu uso BRPI0821301B8 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
IE2007/0934		2007-12-21
IE20070934A IE20070934A1 (en)	2007-12-21	2007-12-21	Efficient aspirin prodrugs
PCT/EP2008/068114 WO2009080795A1 (en)	2007-12-21	2008-12-19	Efficient aspirin prodrugs

Publications (3)

Publication Number	Publication Date
BRPI0821301A2 true BRPI0821301A2 (pt)	2015-06-16
BRPI0821301B1 BRPI0821301B1 (pt)	2019-05-21
BRPI0821301B8 BRPI0821301B8 (pt)	2019-06-04

Family

ID=40428154

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0821301A BRPI0821301B8 (pt)	2007-12-21	2008-12-19	composto de aspirinato de isossorbida, composição farmacêutica, e, seu uso

Country Status (14)

Country	Link
US (1)	US8486974B2 (pt)
EP (1)	EP2222681B1 (pt)
JP (1)	JP5524857B2 (pt)
CN (1)	CN101925604B (pt)
AU (1)	AU2008339961B2 (pt)
BR (1)	BRPI0821301B8 (pt)
CA (1)	CA2709432C (pt)
EA (1)	EA022878B1 (pt)
IE (1)	IE20070934A1 (pt)
IL (1)	IL206424A (pt)
MX (1)	MX2010006878A (pt)
NZ (1)	NZ586304A (pt)
WO (1)	WO2009080795A1 (pt)
ZA (1)	ZA201004371B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2669269B1 (en)	2005-05-27	2019-05-22	The University of North Carolina At Chapel Hill	Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications
CA2706082C (en) *	2008-02-07	2017-10-03	Nicox S.A.	Nitric oxide donor compounds
WO2010009210A2 (en) *	2008-07-17	2010-01-21	Schering Corporation	Acetylsalicyclic acid derivatives useful to treat metabolic syndromes
US20100098733A1 (en) *	2008-10-16	2010-04-22	Novan, Inc.	Nitric oxide releasing particles for oral care applications
WO2011022652A1 (en)	2009-08-21	2011-02-24	Novan, Inc.	Topical gels
EP2467173B8 (en)	2009-08-21	2019-06-19	Novan, Inc.	Wound dressings, methods of using the same and methods of forming the same
WO2011047013A1 (en) *	2009-10-13	2011-04-21	Novan, Inc.	Nitric oxide-releasing coatings
EP2588108A2 (en) *	2010-07-02	2013-05-08	Solvotrin Therapeutics Ltd.	Treatment for dyslipidemia
US8591876B2 (en)	2010-12-15	2013-11-26	Novan, Inc.	Methods of decreasing sebum production in the skin
EP2665730B1 (en) *	2011-01-21	2019-07-24	The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin	Compounds with super-aspirin effects
WO2012118819A2 (en)	2011-02-28	2012-09-07	Novan, Inc.	Nitric oxide-releasing s-nitrosothiol-modified silica particles and methods of making the same
CN102757444B (zh) *	2011-04-29	2016-02-10	南京信诺泰医药有限公司	具有一氧化氮供体性质的苯并呋喃类化合物
CN102225940A (zh) *	2011-05-06	2011-10-26	中国药科大学	一种苯甲酸异山梨醇酯类化合物、其制备方法及医药用途
WO2014052889A1 (en) *	2012-09-27	2014-04-03	The Board Of Trustees Of The University Of Illinois	Anti-inflammatory agents
CN103193789A (zh) *	2013-03-14	2013-07-10	中国药科大学	一种光学活性的丁苯酞开环衍生物、制备方法及医药用途
US9441164B2 (en) *	2013-07-31	2016-09-13	Semiconductor Energy Laboratory Co., Ltd.	Isosorbide derivative, liquid crystal composition, liquid crystal element, and liquid crystal display device
US20170014432A1 (en) *	2014-03-13	2017-01-19	Barry D. Sears	Compositions and methods for reducing chronic low-level inflammation
WO2016135037A1 (en) *	2015-02-23	2016-09-01	Nitto Denko Corporation	Dianhydrohexitol codrug
EP3273951B1 (en)	2015-03-27	2020-07-29	Symbionyx Pharmaceuticals Inc.	Compositions and methods for treating psoriasis
EP3287462A1 (en) *	2016-08-25	2018-02-28	Nitto Denko Corporation	Isosorbide derivatives to treat bacterial biofilms
GB2560769B (en) *	2017-03-24	2020-04-08	Solvotrin Therapeutics Ltd	Compounds and compositions for use in treating psoriasis
CN109384759B (zh) *	2018-12-18	2019-07-23	上海槐丰生物科技有限公司	一种药物化合物及其制备与用途
CN113683623B (zh) *	2021-09-09	2022-08-12	中国人民解放军空军军医大学	一种no供体化合物及其制备方法和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998017673A1 (en) *	1996-10-21	1998-04-30	Cal International Limited	Isosorbide aspirinate esters
ES2142773B1 (es)	1998-10-07	2001-01-01	Lacer Sa	Derivados de mononitrato de isosorbida y su empleo como agentes vasodilatadores con tolerancia desminuida.
ES2258365B1 (es)	2003-10-03	2007-12-01	Lacer, S.A.	Derivados de disulfuro, sulfuro, sulfoxido y sulfona de azucares ciclicos y sus usos.
CN1618798A (zh)	2004-02-25	2005-05-25	鲁南制药股份有限公司	单硝酸异山梨酯的制备方法
EP2588108A2 (en)	2010-07-02	2013-05-08	Solvotrin Therapeutics Ltd.	Treatment for dyslipidemia

2007
- 2007-12-21 IE IE20070934A patent/IE20070934A1/en not_active Application Discontinuation
2008
- 2008-12-19 NZ NZ586304A patent/NZ586304A/en unknown
- 2008-12-19 AU AU2008339961A patent/AU2008339961B2/en not_active Ceased
- 2008-12-19 WO PCT/EP2008/068114 patent/WO2009080795A1/en not_active Ceased
- 2008-12-19 EP EP08865246.6A patent/EP2222681B1/en active Active
- 2008-12-19 JP JP2010538776A patent/JP5524857B2/ja active Active
- 2008-12-19 BR BRPI0821301A patent/BRPI0821301B8/pt not_active IP Right Cessation
- 2008-12-19 MX MX2010006878A patent/MX2010006878A/es active IP Right Grant
- 2008-12-19 CA CA2709432A patent/CA2709432C/en active Active
- 2008-12-19 EA EA201000918A patent/EA022878B1/ru not_active IP Right Cessation
- 2008-12-19 US US12/808,693 patent/US8486974B2/en active Active
- 2008-12-19 CN CN200880125583.3A patent/CN101925604B/zh active Active
2010
- 2010-06-16 IL IL206424A patent/IL206424A/en active IP Right Grant
- 2010-06-21 ZA ZA2010/04371A patent/ZA201004371B/en unknown

Also Published As

Publication number	Publication date
CA2709432A1 (en)	2009-07-02
IL206424A (en)	2015-11-30
IL206424A0 (en)	2010-12-30
MX2010006878A (es)	2010-11-30
EP2222681B1 (en)	2016-02-17
EA022878B1 (ru)	2016-03-31
EA201000918A1 (ru)	2010-12-30
EP2222681A1 (en)	2010-09-01
CN101925604A (zh)	2010-12-22
ZA201004371B (en)	2012-01-25
US20110046182A1 (en)	2011-02-24
US8486974B2 (en)	2013-07-16
JP2011517657A (ja)	2011-06-16
AU2008339961A1 (en)	2009-07-02
JP5524857B2 (ja)	2014-06-18
CN101925604B (zh)	2014-11-26
CA2709432C (en)	2018-07-24
IE20070934A1 (en)	2009-06-24
NZ586304A (en)	2012-07-27
BRPI0821301B8 (pt)	2019-06-04
BRPI0821301B1 (pt)	2019-05-21
WO2009080795A1 (en)	2009-07-02
AU2008339961B2 (en)	2014-02-13

Legal Events

Date	Code	Title	Description
2017-10-10	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2018-05-08	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
2018-07-17	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2018-12-04	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2019-03-26	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2019-05-21	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 21/05/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 21/05/2019, OBSERVADAS AS CONDICOES LEGAIS
2019-06-04	B16C	Correction of notification of the grant [chapter 16.3 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 21/05/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) REF. RPI 2524 DE 21/05/2019 QUANTO AO QUADRO REIVINDICATORIO.
2021-01-12	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time	Free format text: REFERENTE A 12A ANUIDADE.
2021-05-04	B24J	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)	Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2610 DE 12-01-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

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