BRPI0822252A2 - "célula hospedeira microbiana recombinante, método de produção de 2-butanona e método de produção de 2-butanol" - Google Patents
"célula hospedeira microbiana recombinante, método de produção de 2-butanona e método de produção de 2-butanol"Info
- Publication number
- BRPI0822252A2 BRPI0822252A2 BRPI0822252A BRPI0822252A BRPI0822252A2 BR PI0822252 A2 BRPI0822252 A2 BR PI0822252A2 BR PI0822252 A BRPI0822252 A BR PI0822252A BR PI0822252 A BRPI0822252 A BR PI0822252A BR PI0822252 A2 BRPI0822252 A2 BR PI0822252A2
- Authority
- BR
- Brazil
- Prior art keywords
- production method
- host cell
- microbial host
- butanone
- recombinant microbial
- Prior art date
Links
- BTANRVKWQNVYAZ-UHFFFAOYSA-N butan-2-ol Chemical compound CCC(C)O BTANRVKWQNVYAZ-UHFFFAOYSA-N 0.000 title 3
- 238000004519 manufacturing process Methods 0.000 title 2
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 title 1
- 230000000813 microbial effect Effects 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/111,359 US8828704B2 (en) | 2006-05-02 | 2008-04-29 | Fermentive production of four carbon alcohols |
| PCT/US2008/063852 WO2009134276A1 (en) | 2008-04-29 | 2008-05-16 | Fermentive production of four carbon alcohols |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0822252A2 true BRPI0822252A2 (pt) | 2016-11-08 |
Family
ID=40042875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0822252A BRPI0822252A2 (pt) | 2008-04-29 | 2008-05-16 | "célula hospedeira microbiana recombinante, método de produção de 2-butanona e método de produção de 2-butanol" |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8828704B2 (pt) |
| EP (1) | EP2271741B1 (pt) |
| BR (1) | BRPI0822252A2 (pt) |
| CA (1) | CA2722943A1 (pt) |
| ES (1) | ES2491093T3 (pt) |
| WO (1) | WO2009134276A1 (pt) |
Families Citing this family (66)
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| US8273558B2 (en) | 2005-10-26 | 2012-09-25 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| US8206970B2 (en) * | 2006-05-02 | 2012-06-26 | Butamax(Tm) Advanced Biofuels Llc | Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase |
| EP2134849B1 (en) | 2007-04-18 | 2013-07-10 | Butamax (TM) Advanced Biofuels LLC | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
| US8518678B2 (en) * | 2007-12-21 | 2013-08-27 | Butamax(Tm) Advanced Biofuels Llc | Strain comprising increased expression of a CFA coding region for butanol production |
| US8372612B2 (en) * | 2007-12-21 | 2013-02-12 | Butamax(Tm) Advanced Biofuels Llc | Production of four carbon alcohols using improved strain |
| US8188250B2 (en) * | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| US8389252B2 (en) | 2008-05-12 | 2013-03-05 | Butamax(Tm) Advanced Biofuels Llc | Yeast strain for production of four carbon alcohols |
| BRPI0909989A2 (pt) | 2008-06-05 | 2021-06-22 | Butamax Advanced Biofuels Llc | célula de levedura recombinante e método para a produção de um produto |
| US9206447B2 (en) | 2008-09-29 | 2015-12-08 | Butamax Advanced Biofuels Llc | Recombinant yeast host cells comprising FE-S cluster proteins |
| AU2009296227A1 (en) * | 2008-09-29 | 2010-04-01 | Butamax(Tm) Advanced Biofuels Llc | Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria |
| EP2483401B1 (en) | 2009-09-29 | 2017-06-21 | Butamax (TM) Advanced Biofuels LLC | Improved yeast production host cells |
| WO2011073250A2 (en) | 2009-12-15 | 2011-06-23 | Stratley Ag | Method for recovery of organic components from dilute aqueous solutions |
| NZ600509A (en) | 2009-12-29 | 2014-08-29 | Butamax Tm Advanced Biofuels | Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols |
| NZ600585A (en) | 2009-12-29 | 2014-07-25 | Butamax Tm Advanced Biofuels | Expression of hexose kinase in recombinant host cells |
| PH12012501658A1 (en) | 2010-02-17 | 2023-04-28 | Butamax Tm Advanced Biofuels | Improving activity of fe-s cluster requiring proteins |
| CA2801576A1 (en) | 2010-06-17 | 2011-12-22 | Butamax(Tm) Advanced Biofuels Llc | Yeast production culture for the production of butanol |
| US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
| PH12013500158A1 (en) | 2010-07-26 | 2013-03-11 | Genomatica Inc | Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene |
| WO2012033832A2 (en) | 2010-09-07 | 2012-03-15 | Butamax(Tm) Advanced Biofuels Llc | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
| DE102011003387A1 (de) * | 2011-01-31 | 2012-08-02 | Wacker Chemie Ag | Verfahren zur fermentativen Herstellung von 2,3-Butandiol |
| US8759044B2 (en) | 2011-03-23 | 2014-06-24 | Butamax Advanced Biofuels Llc | In situ expression of lipase for enzymatic production of alcohol esters during fermentation |
| US8765425B2 (en) | 2011-03-23 | 2014-07-01 | Butamax Advanced Biofuels Llc | In situ expression of lipase for enzymatic production of alcohol esters during fermentation |
| MX347976B (es) | 2011-03-24 | 2017-05-22 | Butamax(Tm) Advanced Biofuels Llc | Celulas huesped y metodos para producir isobutanol. |
| CA2838519A1 (en) | 2011-06-17 | 2012-12-20 | Butamax Advanced Biofuels Llc | Lignocellulosic hydrolysates as feedstocks for isobutanol fermentation |
| CA2837722A1 (en) | 2011-06-17 | 2012-12-20 | Butamax Advanced Biofuels Llc | Co-products from biofuel production processes and methods of making |
| US20130180164A1 (en) | 2011-07-28 | 2013-07-18 | Butamax(Tm) Advanced Biofuels Llc | Low sulfur fuel compositions having improved lubricity |
| WO2013016717A2 (en) | 2011-07-28 | 2013-01-31 | Butamax(Tm) Advanced Biofuels Llc | Keto-isovalerate decarboxylase enzymes and methods of use thereof |
| JP2015501643A (ja) | 2011-12-09 | 2015-01-19 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 発酵ブロスから生成物アルコールを取り出す方法 |
| CA2861613A1 (en) | 2011-12-30 | 2013-07-04 | Butamax Advanced Biofuels Llc | Fermentative production of alcohols |
| CA2862450A1 (en) | 2011-12-30 | 2013-07-04 | Butamax Advanced Biofuels Llc | Genetic switches for butanol production |
| US10059967B2 (en) | 2012-01-20 | 2018-08-28 | Genomatica, Inc. | Microorganisms and processes for producing terephthalic acid and its salts |
| US9689004B2 (en) | 2012-03-23 | 2017-06-27 | Butamax Advanced Biofuels Llc | Acetate supplemention of medium for butanologens |
| NZ701099A (en) | 2012-05-11 | 2017-04-28 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
| US20140024064A1 (en) | 2012-07-23 | 2014-01-23 | Butamax(Tm) Advanced Biofuels Llc | Processes and systems for the production of fermentative alcohols |
| AU2013295626B2 (en) | 2012-07-26 | 2018-02-01 | Butamax Advanced Biofuels Llc | Butanol purification |
| BR112015003701A2 (pt) | 2012-08-22 | 2017-12-12 | Butamax Advanced Biofuels Llc | células hospedeiras recombinantes, método para aprimoramento, processo para a produção de um álcool, polinucleotídeo isolado, cassete de expressão e composição |
| BR112015005439A8 (pt) | 2012-09-12 | 2022-01-11 | Butamax Advanced Biofuels Llc | Método para recuperar um produto alcoólico de um caldo de fermentação e sistema |
| US9840724B2 (en) | 2012-09-21 | 2017-12-12 | Butamax Advanced Biofuels Llc | Production of renewable hydrocarbon compositions |
| BR112015006296A2 (pt) | 2012-09-21 | 2017-07-04 | Butamax Advanced Biofuels Llc | ''processo, composição bifásica, métodos para a manutenção do estado oxidativo de uma composição, para otimizar a extração do butanol, para aprimorar o rendimento de uma fermetanção de isobutanol, para aprimorar o título de isobutanol produzido durante a fermentação e para aprimorar a taxa de produção de isobutanol durante uma fermentação'' |
| WO2014052670A1 (en) | 2012-09-26 | 2014-04-03 | Butamax (Tm) Advanced Biofuels Llc | Polypeptides with ketol-acid reductoisomerase activity |
| US20140093931A1 (en) | 2012-09-28 | 2014-04-03 | Butamax Advanced Biofuels Llc | Production of fermentation products |
| US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
| BR112015008077A2 (pt) | 2012-10-11 | 2017-12-05 | Butamax Advanced Biofuels Llc | métodos para a produção de um produto de fermentação |
| WO2014081848A1 (en) | 2012-11-20 | 2014-05-30 | Butamax Advanced Biofuels Llc | Butanol purification |
| WO2014086780A2 (en) | 2012-12-07 | 2014-06-12 | Global Bioenergies | Improved fermentation method |
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| US9650624B2 (en) | 2012-12-28 | 2017-05-16 | Butamax Advanced Biofuels Llc | DHAD variants for butanol production |
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| US9156760B2 (en) | 2013-03-15 | 2015-10-13 | Butamax Advanced Biofuels Llc | Method for production of butanol using extractive fermentation |
| WO2014144643A1 (en) | 2013-03-15 | 2014-09-18 | Butamax Advanced Biofuels Llc | Method for producing butanol using extractive fermentation |
| WO2014144210A2 (en) | 2013-03-15 | 2014-09-18 | Butamax Advanced Biofuels Llc | Competitive growth and/or production advantage for butanologen microorganism |
| US9580705B2 (en) | 2013-03-15 | 2017-02-28 | Butamax Advanced Biofuels Llc | DHAD variants and methods of screening |
| WO2014151645A1 (en) | 2013-03-15 | 2014-09-25 | Butamax Advanced Biofuels Llc | Process for maximizing biomass growth and butanol yield by feedback control |
| BR112015020904A2 (pt) | 2013-03-15 | 2017-10-10 | Genomatica Inc | microrganismos e métodos para produção de butadieno e compostos relacionados por assimilação de formiato |
| WO2015002913A1 (en) | 2013-07-03 | 2015-01-08 | Butamax Advanced Biofuels Llc | Partial adaptation for butanol production |
| BR112016009416A2 (pt) | 2013-10-28 | 2017-10-03 | Danisco Us Inc | Levedura seca ativa geneticamente modificada de grande escala |
| US10227623B2 (en) | 2013-11-24 | 2019-03-12 | E I Du Pont De Nemours And Company | High force and high stress destructuring of cellulosic biomass |
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-
2008
- 2008-04-29 US US12/111,359 patent/US8828704B2/en active Active
- 2008-05-16 WO PCT/US2008/063852 patent/WO2009134276A1/en not_active Ceased
- 2008-05-16 ES ES08769487.3T patent/ES2491093T3/es active Active
- 2008-05-16 EP EP08769487.3A patent/EP2271741B1/en active Active
- 2008-05-16 CA CA2722943A patent/CA2722943A1/en not_active Abandoned
- 2008-05-16 BR BRPI0822252A patent/BRPI0822252A2/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2722943A1 (en) | 2009-11-05 |
| EP2271741A1 (en) | 2011-01-12 |
| US8828704B2 (en) | 2014-09-09 |
| WO2009134276A1 (en) | 2009-11-05 |
| ES2491093T3 (es) | 2014-09-05 |
| EP2271741B1 (en) | 2014-06-04 |
| US20090155870A1 (en) | 2009-06-18 |
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