BRPI0715845A2 - Composição farmacêutica para tratamento do câncer de pulmão, método de inibição do crescimento ou invasão do câncer de pulmão e método de tratamento do câncer de pulmão - Google Patents

Composição farmacêutica para tratamento do câncer de pulmão, método de inibição do crescimento ou invasão do câncer de pulmão e método de tratamento do câncer de pulmão

Info

Publication number
BRPI0715845A2
BRPI0715845A2 BRPI0715845-9A2A BRPI0715845A BRPI0715845A2 BR PI0715845 A2 BRPI0715845 A2 BR PI0715845A2 BR PI0715845 A BRPI0715845 A BR PI0715845A BR PI0715845 A2 BRPI0715845 A2 BR PI0715845A2
Authority
BR
Brazil
Prior art keywords
lung cancer
pharmaceutical composition
growth inhibition
cancer treatment
invasion
Prior art date
Application number
BRPI0715845-9A2A
Other languages
English (en)
Inventor
Hyo Jeong Hong
Jun-Whoi Lee
Jin Man Kim
Yeon Sung Son
Eung Suck Lee
Original Assignee
Korea Res Inst Of Bioscience
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Res Inst Of Bioscience filed Critical Korea Res Inst Of Bioscience
Publication of BRPI0715845A2 publication Critical patent/BRPI0715845A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BRPI0715845-9A2A 2006-08-23 2007-08-23 Composição farmacêutica para tratamento do câncer de pulmão, método de inibição do crescimento ou invasão do câncer de pulmão e método de tratamento do câncer de pulmão BRPI0715845A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20060079969 2006-08-23
PCT/KR2007/004045 WO2008023946A1 (en) 2006-08-23 2007-08-23 A pharmaceutical composition for treating lung cancer, a method for inhibiting growth or invasion of lung cancer and a method for treating lung cancer
KR1020070084869A KR100932698B1 (ko) 2006-08-23 2007-08-23 폐암의 치료용 약제학적 조성물 및 이를 이용한 폐암의성장, 전이 억제 및 치료방법

Publications (1)

Publication Number Publication Date
BRPI0715845A2 true BRPI0715845A2 (pt) 2014-11-11

Family

ID=39385312

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0715845-9A2A BRPI0715845A2 (pt) 2006-08-23 2007-08-23 Composição farmacêutica para tratamento do câncer de pulmão, método de inibição do crescimento ou invasão do câncer de pulmão e método de tratamento do câncer de pulmão
BRPI0715844-0A BRPI0715844A2 (pt) 2006-08-23 2007-08-23 Composição farmacêutica para tratamento do colangiocarcinoma, método de inibição do crescimento ou invasão do colangiocarcinoma e método de tratamento do colangiocarcinoma

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0715844-0A BRPI0715844A2 (pt) 2006-08-23 2007-08-23 Composição farmacêutica para tratamento do colangiocarcinoma, método de inibição do crescimento ou invasão do colangiocarcinoma e método de tratamento do colangiocarcinoma

Country Status (10)

Country Link
US (1) US8153122B2 (pt)
EP (2) EP2054083B1 (pt)
JP (3) JP5923233B2 (pt)
KR (2) KR100931976B1 (pt)
CN (2) CN101605560B (pt)
AU (2) AU2007288619A1 (pt)
BR (2) BRPI0715845A2 (pt)
CA (2) CA2661669C (pt)
MX (2) MX2009002064A (pt)
WO (2) WO2008023947A1 (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2661669C (en) * 2006-08-23 2017-02-14 Korea Research Institute Of Bioscience And Biotechnology A pharmaceutical composition for treating cholangiocarcinoma, a method for inhibiting growth or invasion of cholangiocarcinoma and a method for treating cholangniocarcinoma
LT2631248T (lt) 2007-06-15 2018-04-25 Medigene Ag Navikų gydymas, naudojant specifinį anti-l1 antikūną
JP2011514383A (ja) * 2008-03-17 2011-05-06 リジェナークス・バイオファーマスーティカルズ・インコーポレイテッド 改良されたベータチモシンフラグメント
RU2377004C1 (ru) * 2008-07-04 2009-12-27 Федеральное государственное учреждение "Ростовский научно-исследовательский онкологический институт Росмедтехнологий" Способ лечения нерезектабельного рака желчных путей
KR20100060351A (ko) * 2008-11-27 2010-06-07 한국생명공학연구원 Ｌ１ｃａｍ의 활성 또는 발현을 억제하는 물질 및 항암제를포함하는 항암용 조성물
KR101501736B1 (ko) * 2008-12-05 2015-03-12 한국생명공학연구원 인간 및 마우스에서 발현하는 ｌ1ｃａｍ에 특이적으로 결합하는 재조합 단일클론항체 및 그 이용
JP5716257B2 (ja) * 2009-02-06 2015-05-13 国立大学法人 熊本大学 胆管癌特異的糖鎖エピトープを認識するモノクローナル抗体
KR101271964B1 (ko) * 2010-07-08 2013-06-07 강원대학교산학협력단 담낭암 치료용 약제학적 조성물 및 이를 이용한 담낭암의 성장, 전이 억제 및 치료 방법
EP2737317A2 (en) * 2011-07-28 2014-06-04 The Trustees Of The University Of Pennsylvania Methods for diagnosing cancer by characterization of tumor cells associated with pleural or serous fluids
WO2014077648A1 (ko) 2012-11-16 2014-05-22 강원대학교산학협력단 인간 및 마우스 ｌ１ｃａｍ 단백질에 특이적으로 결합하는 항체 및 이의 용도
EP3047039B1 (en) * 2013-09-18 2019-07-31 Memorial Sloan-Kettering Cancer Center Inhibiting cancer metastasis
US10111898B2 (en) * 2014-08-27 2018-10-30 Peptimed, Inc. Anti-tumor compositions and methods
CN104894259A (zh) * 2015-06-01 2015-09-09 北京泱深生物信息技术有限公司 Tex19基因在胆管癌诊断和治疗中的应用
KR101892908B1 (ko) 2015-11-02 2018-08-29 아주대학교산학협력단 글루코코르티코이드계 화합물을 포함하는 비소세포성 폐암 치료용 약학 조성물
US11260062B2 (en) 2015-11-02 2022-03-01 Ajou University Industry-Academic Cooperation Foundation Pharmaceutical composition for treatment of lung cancer comprising glucocorticoid-based compound
KR20190036553A (ko) * 2016-08-02 2019-04-04 메모리얼 슬로안 케터링 캔서 센터 전이성 암의 치료 및 전이성 질환에 대한 모델 시스템
KR20180079232A (ko) * 2016-12-30 2018-07-10 강원대학교산학협력단 L1cam 단백질에 특이적으로 결합하는 항체 및 피리미딘 유사체 및/또는 플라틴계 항암제를 포함하는 암의 예방 또는 치료용 약학적 조성물
US11597764B2 (en) 2017-06-15 2023-03-07 Memorial Sloan Kettering Cancer Center Anti-L1-CAM antibodies and uses thereof
WO2020003210A1 (en) 2018-06-29 2020-01-02 Kangwon National University University-Industry Cooperation Foundation Anti-l1cam antibodies and uses thereof
SG10201902000YA (en) 2019-03-06 2020-10-29 Nat Univ Singapore Isthmin 1 for treatment of lung inflammation
GB201913121D0 (en) 2019-09-11 2019-10-23 Seald As Compositions and methods for treatment of cholangiocarcinoma
GB201913122D0 (en) 2019-09-11 2019-10-23 Seald As Compositions and methods for treatment of cholangiocarcinoma
GB201913124D0 (en) 2019-09-11 2019-10-23 Seald As Compositions and methods for treatment of cholangiocarcinoma
GB201913123D0 (en) 2019-09-11 2019-10-23 Seald As Compositions and methods for treatment of cholangiocarcinoma
CN111053774B (zh) * 2019-12-20 2022-10-11 厦门大学 盐酸他克林在制备治疗胆管癌的药物中的应用
CN112239505B (zh) * 2020-10-13 2022-05-20 上海良润生物医药科技有限公司 重组抗cd171八价抗体及神经来源外泌体的捕获方法
KR20240091226A (ko) * 2021-11-03 2024-06-21 큐론 바이오파마슈티칼 (상하이) 컴퍼니, 리미티드 신규 항 l1cam 항체
CN114657129B (zh) * 2022-04-11 2023-12-01 中山大学孙逸仙纪念医院 一种胆管癌淋巴结转移动物模型及其构建方法
CN114917348B (zh) * 2022-06-21 2023-08-04 四川大学华西医院 神经粘附因子在制备抑制和标记肝癌细胞转移的试剂中的应用
WO2024204325A1 (ja) * 2023-03-28 2024-10-03 東レ株式会社 細胞膜タンパク質を検出する方法
CN117379550A (zh) * 2023-08-22 2024-01-12 上海懿贝瑞生物医药科技有限公司 Spanxb1基因抑制剂及其制备方法和用途
CN119096936A (zh) * 2024-08-28 2024-12-10 南方医科大学第三附属医院（广东省骨科研究院） 一种胆管癌足垫腘窝淋巴结自发转移动物模型的构建方法
CN119492873A (zh) * 2024-10-16 2025-02-21 吉林大学 基于生物偶联策略的细胞表面待测细胞因子富集系统及方法

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US5872225A (en) 1992-06-26 1999-02-16 Case Western Reserve University Method for characterizing the nucleotide sequence of L1CAM and the nucleotide sequence characterized thereby
EP1172654B1 (en) 2000-07-10 2007-10-31 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Diagnostic method based on the detection of the L1 adhesion molecule for ovarian and endometrial tumors
US20040082847A1 (en) * 2002-10-23 2004-04-29 Mcdermott Kathleen B. System and methods for identifying brain regions supporting language
US20040115206A1 (en) * 2002-10-24 2004-06-17 Thomas Primiano Antibody-mediated induction of tumor cell death
WO2005023301A1 (ja) * 2003-09-04 2005-03-17 Chugai Seiyaku Kabushiki Kaisha 胆管癌治療剤および検出薬
EP1623995A1 (en) * 2004-08-06 2006-02-08 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Inhibitors of L1 and ADAM10 for the treatment of carcinomas
CA2661669C (en) * 2006-08-23 2017-02-14 Korea Research Institute Of Bioscience And Biotechnology A pharmaceutical composition for treating cholangiocarcinoma, a method for inhibiting growth or invasion of cholangiocarcinoma and a method for treating cholangniocarcinoma

Also Published As

Publication number Publication date
KR20080018149A (ko) 2008-02-27
EP2051733A1 (en) 2009-04-29
BRPI0715844A2 (pt) 2013-11-26
EP2054083B1 (en) 2013-11-27
US20100196350A1 (en) 2010-08-05
JP2010501549A (ja) 2010-01-21
MX2009002065A (es) 2009-06-30
CA2661669C (en) 2017-02-14
CN101605560A (zh) 2009-12-16
MX2009002064A (es) 2009-06-30
EP2054083A1 (en) 2009-05-06
AU2007288620A1 (en) 2008-02-28
CA2661669A1 (en) 2008-02-28
CN101605560B (zh) 2013-06-26
AU2007288619A1 (en) 2008-02-28
JP2010501548A (ja) 2010-01-21
CA2661665A1 (en) 2008-02-28
JP2015007045A (ja) 2015-01-15
KR100931976B1 (ko) 2009-12-15
KR100932698B1 (ko) 2009-12-21
WO2008023946A1 (en) 2008-02-28
JP5923233B2 (ja) 2016-05-24
EP2054083A4 (en) 2010-03-24
WO2008023947A1 (en) 2008-02-28
US8153122B2 (en) 2012-04-10
AU2007288620B2 (en) 2012-08-30
CN101528258A (zh) 2009-09-09
KR20080018150A (ko) 2008-02-27

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