BRPI0905869A2 - Método para purificar naproxcinod, e, naproxcinod. - Google Patents

Método para purificar naproxcinod, e, naproxcinod.

Info

Publication number
BRPI0905869A2
BRPI0905869A2 BRPI0905869-9A BRPI0905869A BRPI0905869A2 BR PI0905869 A2 BRPI0905869 A2 BR PI0905869A2 BR PI0905869 A BRPI0905869 A BR PI0905869A BR PI0905869 A2 BRPI0905869 A2 BR PI0905869A2
Authority
BR
Brazil
Prior art keywords
naproxcinod
purifying
purifying naproxcinod
Prior art date
Application number
BRPI0905869-9A
Other languages
English (en)
Inventor
Pietro Allergrini
Tiziano Scubla
Nicoletta Toniutti
Romano Rivolta
Thierry Delahaique
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Publication of BRPI0905869A2 publication Critical patent/BRPI0905869A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/02—Preparation of esters of nitric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BRPI0905869-9A 2008-06-20 2009-06-18 Método para purificar naproxcinod, e, naproxcinod. BRPI0905869A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000325A ITRM20080325A1 (it) 2008-06-20 2008-06-20 Metodo per purificare 4-(nitroosi)butil(2s)-2-(6-metossi-2-naftil) propanoato
PCT/IB2009/006382 WO2009153668A2 (en) 2008-06-20 2009-06-18 Method for purifying 4-(nitrooxy)butyl(2s)-2-(6-methoxy-2-naphthyl)propanoate

Publications (1)

Publication Number Publication Date
BRPI0905869A2 true BRPI0905869A2 (pt) 2015-06-30

Family

ID=40302064

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0905869-9A BRPI0905869A2 (pt) 2008-06-20 2009-06-18 Método para purificar naproxcinod, e, naproxcinod.

Country Status (15)

Country Link
US (1) US8329937B2 (pt)
EP (1) EP2288590A2 (pt)
JP (1) JP2011524892A (pt)
KR (1) KR20110037927A (pt)
CN (1) CN101874014A (pt)
AR (1) AR074885A1 (pt)
AU (1) AU2009261666A1 (pt)
BR (1) BRPI0905869A2 (pt)
CA (1) CA2705634A1 (pt)
IL (1) IL204701A0 (pt)
IT (1) ITRM20080325A1 (pt)
NZ (1) NZ584336A (pt)
RU (1) RU2010120745A (pt)
WO (1) WO2009153668A2 (pt)
ZA (1) ZA201002316B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103058861B (zh) * 2013-01-08 2015-03-18 安徽赛诺医药化工有限公司 一种萘普西诺中间体的合成新方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3775796B2 (ja) * 1993-10-06 2006-05-17 ニコックス エス エイ 抗炎症活性及び／又は鎮痛活性を有する硝酸エステル類及びそれらの製造方法
IT1313596B1 (it) * 1999-08-04 2002-09-09 Nicox Sa Processo per la preparazione di nitrossialchil esteri del naproxene
WO2003045896A1 (en) * 2001-11-27 2003-06-05 Astrazeneca Ab New process
US20040028747A1 (en) * 2002-08-06 2004-02-12 Tucker Christopher J. Crystalline drug particles prepared using a controlled precipitation process
ITMI20021861A1 (it) * 2002-08-29 2004-02-29 Nicox Sa Procedimento di sintesi di nitrossialchilesteri di acidi carbossilici, intermedi impiegabili in detto procedimento e loro preparazione.
MX2009011502A (es) * 2007-04-25 2009-11-09 Nicox Sa Uso de 4-(nitrooxi)-butil-(s)-2-(6-metoxi-2-naftil)-propanoato para el tratamiento del dolor y la inflamacion.

Also Published As

Publication number Publication date
JP2011524892A (ja) 2011-09-08
AR074885A1 (es) 2011-02-23
CN101874014A (zh) 2010-10-27
EP2288590A2 (en) 2011-03-02
IL204701A0 (en) 2010-11-30
CA2705634A1 (en) 2009-12-23
AU2009261666A1 (en) 2009-12-23
US20100256411A1 (en) 2010-10-07
ITRM20080325A1 (it) 2009-12-21
ZA201002316B (en) 2011-06-29
US8329937B2 (en) 2012-12-11
RU2010120745A (ru) 2012-07-27
WO2009153668A2 (en) 2009-12-23
NZ584336A (en) 2012-08-31
WO2009153668A3 (en) 2010-02-11
KR20110037927A (ko) 2011-04-13

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.