BRPI0907052B8 - processo para a preparação de compostos - Google Patents

processo para a preparação de compostos

Info

Publication number
BRPI0907052B8
BRPI0907052B8 BRPI0907052A BRPI0907052A BRPI0907052B8 BR PI0907052 B8 BRPI0907052 B8 BR PI0907052B8 BR PI0907052 A BRPI0907052 A BR PI0907052A BR PI0907052 A BRPI0907052 A BR PI0907052A BR PI0907052 B8 BRPI0907052 B8 BR PI0907052B8
Authority
BR
Brazil
Prior art keywords
preparing compounds
formula
compound
compounds
meanings
Prior art date
Application number
BRPI0907052A
Other languages
English (en)
Inventor
Helmreich Matthias
Brandner Mike
Original Assignee
Poxel Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poxel Sas filed Critical Poxel Sas
Publication of BRPI0907052A2 publication Critical patent/BRPI0907052A2/pt
Publication of BRPI0907052B1 publication Critical patent/BRPI0907052B1/pt
Publication of BRPI0907052B8 publication Critical patent/BRPI0907052B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/10—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

processo para a preparação de compostos. processo para a preparação de compostos de fórmula i em que r1, r2, r3, r4, r5 e r6 terem os significados indicados na reivindicação 1, que compreende a reação de um composto de fórmula ii em que r1, r2, r3, r4 terem os significados acima, com um composto de fórmula iii em que r5, r6 têm os significados indicados acima.
BRPI0907052A 2008-02-02 2009-01-15 processo para a preparação de compostos BRPI0907052B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102008007314A DE102008007314A1 (de) 2008-02-02 2008-02-02 Verfahren zur Herstellung von 3,6-Dihydro-1,3,5-triazinderivaten
DE102008007314.8 2008-02-02
PCT/EP2009/000212 WO2009095159A1 (de) 2008-02-02 2009-01-15 Verfahren zur herstellung von 3, 6-dihydro-l, 3, 5-triazinderivaten aus metformin- und paraldehydderivaten

Publications (3)

Publication Number Publication Date
BRPI0907052A2 BRPI0907052A2 (pt) 2015-07-07
BRPI0907052B1 BRPI0907052B1 (pt) 2020-09-24
BRPI0907052B8 true BRPI0907052B8 (pt) 2021-05-25

Family

ID=40459622

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0907052A BRPI0907052B8 (pt) 2008-02-02 2009-01-15 processo para a preparação de compostos

Country Status (24)

Country Link
US (1) US8461331B2 (pt)
EP (1) EP2240456B1 (pt)
JP (1) JP5542066B2 (pt)
KR (1) KR101553568B1 (pt)
CN (1) CN101932566B (pt)
AR (1) AR070329A1 (pt)
AT (1) ATE519752T1 (pt)
AU (1) AU2009210293B2 (pt)
BR (1) BRPI0907052B8 (pt)
CA (1) CA2713236C (pt)
CY (1) CY1111837T1 (pt)
DE (1) DE102008007314A1 (pt)
DK (1) DK2240456T3 (pt)
EA (1) EA017062B1 (pt)
ES (1) ES2368116T3 (pt)
HR (1) HRP20110644T1 (pt)
IL (1) IL206816A (pt)
MX (1) MX2010008282A (pt)
PL (1) PL2240456T3 (pt)
PT (1) PT2240456E (pt)
RS (1) RS51968B (pt)
SI (1) SI2240456T1 (pt)
WO (1) WO2009095159A1 (pt)
ZA (1) ZA201006211B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2646422B1 (en) 2010-12-01 2015-07-08 Poxel Separation of triazine derivatives enantiomers using tartaric acid
EP3691650A1 (en) 2017-10-02 2020-08-12 Poxel Methods of treating heart failure with preserved ejection fraction
MY203360A (en) 2018-06-06 2024-06-26 Metavant Sciences Gmbh Methods of treating subjects having diabetes with chronic kidney disease
CA3103324A1 (en) 2018-06-14 2019-12-19 Poxel Film-coated tablet comprising a triazine derivative for use in the treatment of diabetes
CN109655544B (zh) * 2018-12-25 2022-08-12 广东华南药业集团有限公司 一种盐酸二甲双胍及其制剂的质量控制方法
WO2025233968A1 (en) * 2024-05-10 2025-11-13 Council Of Scientific And Industrial Research A process for the preparation of imeglimin compounds

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1537604A (fr) 1966-09-26 1968-08-23 Sandoz Sa Procédé de préparation de biguanides
GB1250531A (pt) * 1969-01-01 1971-10-20
DE2117015A1 (de) 1971-04-02 1972-10-26 Schering Ag 1,2-Biguanide
SU458538A1 (ru) * 1973-06-14 1975-01-30 Уфимский Нефтяной Институт Способ совместного получени 1,3диеновых углеводородов и гексаметилентетрамина
JPH061779A (ja) * 1992-02-06 1994-01-11 Wakamoto Pharmaceut Co Ltd ベンズオキサジノン誘導体
US5767294A (en) * 1993-02-17 1998-06-16 Hoechst Celanese Corporation Process for the production of trioxane from formaldehyde
US5627282A (en) * 1996-01-03 1997-05-06 Yukong Limited Process for the preparation of optically pure 1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid and its derivatives
FR2804113B1 (fr) 2000-01-26 2004-06-18 Lipha Derives animes de dihydro-1,3,5-triazine et leurs applications en therapeutique
CN100551916C (zh) * 2002-12-17 2009-10-21 浜理药品工业株式会社 新的2,4-二氨基-1,3,5-三嗪衍生物
US7622469B2 (en) 2002-12-17 2009-11-24 Hamari Chemicals, Ltd. 2,4-diamino-1,3,5-triazine derivatives
FR2853650B1 (fr) * 2003-04-10 2006-07-07 Merck Sante Sas Procede de dedoublement d'amines utiles pour le traitement de desordres associes au syndrome d'insulino-resistance
TWI410413B (zh) * 2006-04-26 2013-10-01 Sumitomo Seika Chemicals Preparation method of methylene disulfonate compound

Also Published As

Publication number Publication date
JP5542066B2 (ja) 2014-07-09
CA2713236A1 (en) 2009-08-06
KR101553568B1 (ko) 2015-09-16
EP2240456B1 (de) 2011-08-10
PL2240456T3 (pl) 2011-11-30
KR20100103698A (ko) 2010-09-27
CN101932566A (zh) 2010-12-29
ES2368116T3 (es) 2011-11-14
SI2240456T1 (sl) 2012-01-31
CN101932566B (zh) 2013-04-10
EA201001252A1 (ru) 2010-12-30
EP2240456A1 (de) 2010-10-20
MX2010008282A (es) 2010-11-30
DK2240456T3 (da) 2011-09-26
EA017062B1 (ru) 2012-09-28
ATE519752T1 (de) 2011-08-15
CA2713236C (en) 2016-03-22
AU2009210293B2 (en) 2013-05-23
JP2011510940A (ja) 2011-04-07
DE102008007314A1 (de) 2009-08-06
US20110118463A1 (en) 2011-05-19
US8461331B2 (en) 2013-06-11
BRPI0907052A2 (pt) 2015-07-07
AR070329A1 (es) 2010-03-31
PT2240456E (pt) 2011-09-27
HRP20110644T1 (hr) 2011-10-31
BRPI0907052B1 (pt) 2020-09-24
IL206816A (en) 2013-02-28
CY1111837T1 (el) 2015-10-07
ZA201006211B (en) 2011-05-25
WO2009095159A1 (de) 2009-08-06
AU2009210293A1 (en) 2009-08-06
IL206816A0 (en) 2010-12-30
RS51968B (sr) 2012-02-29

Similar Documents

Publication Publication Date Title
BRPI0816911A8 (pt) Processo para preparação de 4-aminobut-2-enolidas
BRPI0615705A2 (pt) processo para preparar um composto, e, composto
MX2010002243A (es) Derivados fungicidas de 2-alquiltio-2-quinoliniloxi-acetamida.
BRPI0814153B8 (pt) Método para preparar derivados de 5-haloalquil-4,5-diidroisoxazol e compostos de partida úteis no método
UY31524A1 (es) Nuevos compuestos 010
BRPI0518758A2 (pt) compostos de acetamida como fungicidas
BRPI0520870B8 (pt) compostos intermediários para a preparação de alfa-mercaptoacetanilidas de s-triazolila
CY1109911T1 (el) Πυρρολοβενζοδιαζεπινες
ECSP099818A (es) Procesos para la preparacion de pirazoles
CO6210751A2 (es) Derivados de indolinona y procedimiento para su fabricacion
MA32647B1 (fr) Composés pyrrole
MX2010002244A (es) Nuevos fungicidas.
TN2010000064A1 (en) Novel herbicides
UA103625C2 (en) 5-hetrocyclylalkyl-3-hydroxy-2-phenylcyclopent-2-enons as herbicides
MX2010001364A (es) Derivados de ciclopentandiona puenteados triciclicos como herbicidas.
BR112014000471A2 (pt) processo para preparo de derivados de diamida de ácido antranílico substituídos com tetrazol por meio da reação de ácidos pirazóis com ésteres antranílicos
BRPI0712889A8 (pt) composto, processo para a preparação de um composto, composto intermediário, e, composição farmacêutica.
BRPI0514137A (pt) uso de pelo menos um composto heterocìclico, composição de combustìvel, concentrado de aditivos, e, processo para preparar uma composição de combustìvel
UA106880C2 (uk) Нові гербіциди
CY1115623T1 (el) Μεθοδος για την συνθεση 7,8-διμεθοξυ-1,3-διϋδρο-2η-3-βενζαζεπιν-2-ονης και εφαρμογη αυτης στη συνθεση της ιβαμπραδινης καθως επισης αλατων προσθηκης αυτης με ενα φαρμακευτικως αποδεκτο οξυ
EP2578587A4 (en) PYRAZOLE DERIVATIVES
CR10540A (es) Derivados ciclopropil amina
AR064658A1 (es) Proceso para preparar duloxetina y sus compuestos relacionados, asi como tambien intermediarios utiles en la misma
BR112013001721A2 (pt) processo de síntese de compostos de ureia substituída
BRPI0808570B8 (pt) processo para a preparação de inibidores de glyt-1

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 24/09/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/01/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 15A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2757 DE 07-11-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.