BRPI0908128A2 - Método para isolamento de ácido nucleicos apoptóticos ou fetais livres de células - Google Patents
Método para isolamento de ácido nucleicos apoptóticos ou fetais livres de célulasInfo
- Publication number
- BRPI0908128A2 BRPI0908128A2 BRPI0908128-3A BRPI0908128A BRPI0908128A2 BR PI0908128 A2 BRPI0908128 A2 BR PI0908128A2 BR PI0908128 A BRPI0908128 A BR PI0908128A BR PI0908128 A2 BRPI0908128 A2 BR PI0908128A2
- Authority
- BR
- Brazil
- Prior art keywords
- isolation
- nucleic acids
- cell free
- fetal nucleic
- free apoptotic
- Prior art date
Links
- 230000001640 apoptogenic effect Effects 0.000 title 1
- 230000001605 fetal effect Effects 0.000 title 1
- 238000002955 isolation Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2806408P | 2008-02-12 | 2008-02-12 | |
| PCT/US2009/033375 WO2009102632A2 (en) | 2008-02-12 | 2009-02-06 | Method for isolating cell free apoptotic or fetal nucleic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0908128A2 true BRPI0908128A2 (pt) | 2015-08-04 |
Family
ID=40957453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0908128-3A BRPI0908128A2 (pt) | 2008-02-12 | 2009-02-06 | Método para isolamento de ácido nucleicos apoptóticos ou fetais livres de células |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20110171640A1 (pt) |
| EP (1) | EP2242857A4 (pt) |
| JP (1) | JP2011511644A (pt) |
| CN (1) | CN101999003A (pt) |
| BR (1) | BRPI0908128A2 (pt) |
| CA (1) | CA2714212A1 (pt) |
| MX (1) | MX2010008820A (pt) |
| WO (1) | WO2009102632A2 (pt) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9447467B2 (en) | 2009-04-21 | 2016-09-20 | Genetic Technologies Limited | Methods for obtaining fetal genetic material |
| US20120315633A1 (en) * | 2009-12-23 | 2012-12-13 | Genetic Technologies Limited | Methods of enriching and detecting fetal nucleic acids |
| US20120034603A1 (en) * | 2010-08-06 | 2012-02-09 | Tandem Diagnostics, Inc. | Ligation-based detection of genetic variants |
| US10167508B2 (en) | 2010-08-06 | 2019-01-01 | Ariosa Diagnostics, Inc. | Detection of genetic abnormalities |
| US20140342940A1 (en) | 2011-01-25 | 2014-11-20 | Ariosa Diagnostics, Inc. | Detection of Target Nucleic Acids using Hybridization |
| US20130040375A1 (en) | 2011-08-08 | 2013-02-14 | Tandem Diagnotics, Inc. | Assay systems for genetic analysis |
| US10533223B2 (en) | 2010-08-06 | 2020-01-14 | Ariosa Diagnostics, Inc. | Detection of target nucleic acids using hybridization |
| US8700338B2 (en) | 2011-01-25 | 2014-04-15 | Ariosa Diagnosis, Inc. | Risk calculation for evaluation of fetal aneuploidy |
| US11203786B2 (en) | 2010-08-06 | 2021-12-21 | Ariosa Diagnostics, Inc. | Detection of target nucleic acids using hybridization |
| US11031095B2 (en) | 2010-08-06 | 2021-06-08 | Ariosa Diagnostics, Inc. | Assay systems for determination of fetal copy number variation |
| US20130261003A1 (en) | 2010-08-06 | 2013-10-03 | Ariosa Diagnostics, In. | Ligation-based detection of genetic variants |
| US11270781B2 (en) | 2011-01-25 | 2022-03-08 | Ariosa Diagnostics, Inc. | Statistical analysis for non-invasive sex chromosome aneuploidy determination |
| US9994897B2 (en) | 2013-03-08 | 2018-06-12 | Ariosa Diagnostics, Inc. | Non-invasive fetal sex determination |
| US10131947B2 (en) * | 2011-01-25 | 2018-11-20 | Ariosa Diagnostics, Inc. | Noninvasive detection of fetal aneuploidy in egg donor pregnancies |
| WO2012129363A2 (en) | 2011-03-24 | 2012-09-27 | President And Fellows Of Harvard College | Single cell nucleic acid detection and analysis |
| EP3412773B1 (en) * | 2011-09-26 | 2022-11-16 | QIAGEN GmbH | Rapid method for isolating extracellular nucleic acids |
| US10289800B2 (en) | 2012-05-21 | 2019-05-14 | Ariosa Diagnostics, Inc. | Processes for calculating phased fetal genomic sequences |
| AU2013292287A1 (en) | 2012-07-19 | 2015-02-19 | Ariosa Diagnostics, Inc. | Multiplexed sequential ligation-based detection of genetic variants |
| DE202013012824U1 (de) | 2012-09-04 | 2020-03-10 | Guardant Health, Inc. | Systeme zum Erfassen von seltenen Mutationen und einer Kopienzahlvariation |
| US20160040229A1 (en) | 2013-08-16 | 2016-02-11 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| US11913065B2 (en) | 2012-09-04 | 2024-02-27 | Guardent Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| US10876152B2 (en) | 2012-09-04 | 2020-12-29 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
| WO2014160233A1 (en) * | 2013-03-13 | 2014-10-02 | Abbott Molecular Inc. | Systems and methods for isolating nucleic acids |
| ES2660989T3 (es) | 2013-12-28 | 2018-03-27 | Guardant Health, Inc. | Métodos y sistemas para detectar variantes genéticas |
| JP6019254B2 (ja) * | 2014-04-23 | 2016-11-02 | 株式会社ニチレイバイオサイエンス | 標的マーカー検出用組合せ物 |
| AU2016277476B2 (en) | 2015-06-10 | 2022-07-21 | Qiagen Gmbh | Method for isolating extracellular nucleic acids using anion exchange particles |
| CN117174167A (zh) | 2015-12-17 | 2023-12-05 | 夸登特健康公司 | 通过分析无细胞dna确定肿瘤基因拷贝数的方法 |
| US9850523B1 (en) | 2016-09-30 | 2017-12-26 | Guardant Health, Inc. | Methods for multi-resolution analysis of cell-free nucleic acids |
| KR20240155386A (ko) | 2016-09-30 | 2024-10-28 | 가던트 헬쓰, 인크. | 무세포 핵산의 다중-해상도 분석 방법 |
| CN115639361B (zh) * | 2018-02-09 | 2025-07-18 | 北京豪迈生物工程股份有限公司 | 表面结合有抗体的颗粒 |
| CN109342718A (zh) * | 2018-09-29 | 2019-02-15 | 宁波奥丞生物科技有限公司 | 一种磁微粒化学发光检测方法 |
| CA3126428A1 (en) | 2019-01-31 | 2020-08-06 | Guardant Health, Inc. | Compositions and methods for isolating cell-free dna |
| EP3959312A1 (en) | 2019-04-26 | 2022-03-02 | Thermo Fisher Scientific Baltics Uab | Isolated nucleic acid binding domains |
| AU2021345359A1 (en) * | 2020-09-21 | 2023-05-11 | Enumera Molecular, Inc. | Compositions and methods for isolation of cell-free dna |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4963658A (en) * | 1987-09-04 | 1990-10-16 | Molecular Devices Corporation | DNA detection method |
| US4978608A (en) * | 1987-09-04 | 1990-12-18 | Molecular Devices Corporation | DNA detection system |
| US6630301B1 (en) * | 1997-03-14 | 2003-10-07 | The Penn State Research Foundation | Detection of extracellular tumor-associated nucleic acid in blood plasma or serum |
| GB9704444D0 (en) * | 1997-03-04 | 1997-04-23 | Isis Innovation | Non-invasive prenatal diagnosis |
| GB9709728D0 (en) * | 1997-05-13 | 1997-07-02 | Dynal As | Single step method |
| US6492144B1 (en) * | 1997-05-30 | 2002-12-10 | Diagen Corporation | Methods for detection of nucleic acid sequences in urine |
| DK0920539T3 (da) * | 1997-05-30 | 2006-07-24 | Xenomics | Fremgangsmåder til detektion af nukleinsyresekvenser i urin |
| WO2001055339A2 (en) * | 2000-01-25 | 2001-08-02 | Hyseq, Inc. | Novel fetal nucleic acids and polypeptides |
| NZ535044A (en) * | 2002-03-01 | 2008-12-24 | Ravgen Inc | Non-invasive method to determine the genetic sequence of foetal DNA from a sample from a pregnant female thereby detecting any alternation in gene sequence as compared with the wild type sequence |
| US7442506B2 (en) * | 2002-05-08 | 2008-10-28 | Ravgen, Inc. | Methods for detection of genetic disorders |
| EP1664077B1 (en) * | 2003-09-05 | 2016-04-13 | Trustees of Boston University | Method for non-invasive prenatal diagnosis |
| US8158410B2 (en) * | 2005-01-18 | 2012-04-17 | Biocept, Inc. | Recovery of rare cells using a microchannel apparatus with patterned posts |
| US20070224597A1 (en) * | 2006-03-23 | 2007-09-27 | Biocept, Inc. | Isolating fetal trophoblasts |
| EP3260556B1 (en) * | 2006-05-31 | 2019-07-31 | Sequenom, Inc. | Methods for the extraction of nucleic acid from a sample |
-
2009
- 2009-02-06 BR BRPI0908128-3A patent/BRPI0908128A2/pt not_active IP Right Cessation
- 2009-02-06 MX MX2010008820A patent/MX2010008820A/es active IP Right Grant
- 2009-02-06 CN CN2009801128419A patent/CN101999003A/zh active Pending
- 2009-02-06 US US12/865,380 patent/US20110171640A1/en not_active Abandoned
- 2009-02-06 EP EP09711041A patent/EP2242857A4/en not_active Withdrawn
- 2009-02-06 CA CA2714212A patent/CA2714212A1/en not_active Abandoned
- 2009-02-06 WO PCT/US2009/033375 patent/WO2009102632A2/en not_active Ceased
- 2009-02-06 JP JP2010546840A patent/JP2011511644A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| MX2010008820A (es) | 2010-09-07 |
| EP2242857A4 (en) | 2011-08-17 |
| CN101999003A (zh) | 2011-03-30 |
| WO2009102632A2 (en) | 2009-08-20 |
| WO2009102632A3 (en) | 2009-11-26 |
| US20110171640A1 (en) | 2011-07-14 |
| CA2714212A1 (en) | 2009-08-20 |
| JP2011511644A (ja) | 2011-04-14 |
| EP2242857A2 (en) | 2010-10-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL2285816T5 (pl) | Sposób izolacji kwasów nukleinowych | |
| EP2242857A4 (en) | METHOD FOR ISOLATING APOPTOTIC NUCLEIC ACIDS OR F RATES WITHOUT CELLS | |
| ES2626488T8 (es) | Procedimientos para la síntesis de ácidos nucleicos funcionalizados | |
| BRPI0923225A2 (pt) | metodo para sintese de acidos nucleicos modificados no atomo de fosforo | |
| BRPI0909212A2 (pt) | Composições e método para sequeciamento de ácido nucléico | |
| SMT201600475B (it) | Procedimenti per la preparazione di inibitori di sglt2 | |
| GB0814570D0 (en) | Isolation of nucleic acid | |
| GB0912909D0 (en) | Probes for specific analysis of nucleic acids | |
| BRPI0920356A2 (pt) | Processo para a preparação de compostos úteis como inibidores de sglt | |
| BRPI1011936A2 (pt) | métodos biológicos para a preparação de ácido adípico | |
| PL2254698T3 (pl) | Mobilny zestaw aparatury dla izolowania kwasów nukleinowych | |
| BRPI0923748A2 (pt) | Método para a preparação de dióis | |
| DK2626438T3 (da) | Bevarelse af føtale nukleinsyrer i maternel plasma | |
| UY33094A (es) | Procedimiento para la preparacion de dronedarona | |
| BRPI0816258A2 (pt) | processo para a preparação de compostos úteis como inibidores de sglt | |
| BRPI0910286A2 (pt) | métodos para transformação de levedura | |
| IT1401447B1 (it) | Metodo per il trasferimento quantitativo di analiti | |
| BRPI0908412A2 (pt) | método para purificar álcool de fermentação | |
| ES2386414T8 (es) | Procedimiento para la desparafinación de muestras biológicas | |
| BRPI0817199A2 (pt) | Identificaçãob e isolamento de células fetais e ácido nucleico | |
| BRPI0924215A2 (pt) | método e sistema para execução de medição | |
| BRPI0917160A2 (pt) | método para concentrar biopolímeros sensíveis ao cisalhamento | |
| BRPI1011394A8 (pt) | método para avaliação de responsividade de linforma de células b ao tratamento com anticorpos anti-cd40 | |
| BR112012002500A2 (pt) | Processo para o preparo de derivados de ácido 1- (2-halobifenil-4-yl) - ciclopropanocarboxílico | |
| BRPI0813788A2 (pt) | Processo para preparação de metacrilato de alila |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |