BRPI1011394A8 - método para avaliação de responsividade de linforma de células b ao tratamento com anticorpos anti-cd40 - Google Patents

método para avaliação de responsividade de linforma de células b ao tratamento com anticorpos anti-cd40 Download PDF

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Publication number
BRPI1011394A8
BRPI1011394A8 BRPI1011394A BRPI1011394A BRPI1011394A8 BR PI1011394 A8 BRPI1011394 A8 BR PI1011394A8 BR PI1011394 A BRPI1011394 A BR PI1011394A BR PI1011394 A BRPI1011394 A BR PI1011394A BR PI1011394 A8 BRPI1011394 A8 BR PI1011394A8
Authority
BR
Brazil
Prior art keywords
linforma
responsiveness
assessing
cell
antibody treatment
Prior art date
Application number
BRPI1011394A
Other languages
English (en)
Inventor
Burington Bart
Dornan David
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BRPI1011394A2 publication Critical patent/BRPI1011394A2/pt
Publication of BRPI1011394A8 publication Critical patent/BRPI1011394A8/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
BRPI1011394A 2009-04-18 2010-04-17 método para avaliação de responsividade de linforma de células b ao tratamento com anticorpos anti-cd40 BRPI1011394A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17061509P 2009-04-18 2009-04-18
PCT/US2010/031528 WO2010121231A1 (en) 2009-04-18 2010-04-17 Methods for assessing responsiveness of b-cell lymphoma to treatment with anti-cd40 antibodies

Publications (2)

Publication Number Publication Date
BRPI1011394A2 BRPI1011394A2 (pt) 2016-03-15
BRPI1011394A8 true BRPI1011394A8 (pt) 2018-06-26

Family

ID=42358184

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1011394A BRPI1011394A8 (pt) 2009-04-18 2010-04-17 método para avaliação de responsividade de linforma de células b ao tratamento com anticorpos anti-cd40

Country Status (12)

Country Link
US (1) US9617600B2 (pt)
EP (1) EP2419531B1 (pt)
JP (1) JP5836929B2 (pt)
KR (1) KR101787768B1 (pt)
CN (1) CN102459639A (pt)
AU (1) AU2010236168B2 (pt)
BR (1) BRPI1011394A8 (pt)
CA (1) CA2758523C (pt)
ES (1) ES2605228T3 (pt)
IL (1) IL215707A (pt)
MX (1) MX2011010938A (pt)
WO (1) WO2010121231A1 (pt)

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CN113461819B (zh) 2011-04-29 2024-01-02 埃派斯进有限公司 抗-cd40抗体及其使用方法
EP2568290B1 (en) 2011-09-12 2017-02-22 Atrys Health, SA Methods for prognosis of diffuse large B-cell lymphoma
US20150038511A1 (en) 2012-08-09 2015-02-05 Celgene Corporation Treatment of immune-related and inflammatory diseases
NZ727295A (en) * 2012-08-09 2018-06-29 Celgene Corp Treatment of immune-related and inflammatory diseases
AU2013337903B2 (en) 2012-10-30 2018-08-16 Apexigen, Inc. Anti-CD40 antibodies and methods of use
US10245266B2 (en) 2014-05-19 2019-04-02 Celgene Corporation 3-(4-((4-morpholinomethyl-benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione for the treatment of systemic lupus erythematosus
CA2999179A1 (en) 2015-09-25 2017-03-30 Celgene Corporation Methods for treating diffuse large b-cell lymphoma and the use of biomarkers as a predictor of responsiveness to drugs
KR102379464B1 (ko) 2016-06-20 2022-03-29 키맵 리미티드 항-pd-l1 항체
WO2022120038A1 (en) * 2020-12-02 2022-06-09 Albert Einstein College Of Medicine Method for predicting patient response to cd40-targeted therapies
CN117092336A (zh) * 2023-06-16 2023-11-21 中国医学科学院北京协和医院 血浆n4bp1、creb1、ubap2、deaf1自身抗体标志物在弥漫大b细胞淋巴瘤预后预测中的应用

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Also Published As

Publication number Publication date
KR101787768B1 (ko) 2017-10-18
IL215707A0 (en) 2012-01-31
US20120123695A1 (en) 2012-05-17
ES2605228T3 (es) 2017-03-13
JP5836929B2 (ja) 2015-12-24
EP2419531B1 (en) 2016-09-07
JP2012523838A (ja) 2012-10-11
CA2758523C (en) 2019-03-12
BRPI1011394A2 (pt) 2016-03-15
CA2758523A1 (en) 2010-10-21
CN102459639A (zh) 2012-05-16
KR20120013992A (ko) 2012-02-15
MX2011010938A (es) 2012-01-12
IL215707A (en) 2016-08-31
WO2010121231A1 (en) 2010-10-21
AU2010236168A1 (en) 2011-11-10
AU2010236168B2 (en) 2015-08-13
EP2419531A1 (en) 2012-02-22
US9617600B2 (en) 2017-04-11

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B11D Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time