BRPI0908456A2 - derivados de bifenil restritos estruturalmente para uso como inibidores do vírus da hepatite c - Google Patents

derivados de bifenil restritos estruturalmente para uso como inibidores do vírus da hepatite c

Info

Publication number
BRPI0908456A2
BRPI0908456A2 BRPI0908456A BRPI0908456A BRPI0908456A2 BR PI0908456 A2 BRPI0908456 A2 BR PI0908456A2 BR PI0908456 A BRPI0908456 A BR PI0908456A BR PI0908456 A BRPI0908456 A BR PI0908456A BR PI0908456 A2 BRPI0908456 A2 BR PI0908456A2
Authority
BR
Brazil
Prior art keywords
hepatitis
biphenyl derivatives
virus inhibitors
structurally restricted
structurally
Prior art date
Application number
BRPI0908456A
Other languages
English (en)
Inventor
Bachand Carol
Belema Makonen
Goodrich Jason
Lavoie Rico
D. Lopez Omar
A. Meanwell Nicholas
N. Nguyen Van
Lee Romine Jeffrey
B. Snyder Lawrence
R. St. Laurent Denis
Yang Fukang
R. Langley David
Wang Gan
G. Hamann Lawrence
Martel Alain
H. Ruediger Edward
H. Deon Daniel
A. James Clint
C. Good Andrew
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of BRPI0908456A2 publication Critical patent/BRPI0908456A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
BRPI0908456A 2008-02-13 2009-02-02 derivados de bifenil restritos estruturalmente para uso como inibidores do vírus da hepatite c BRPI0908456A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2826608P 2008-02-13 2008-02-13
PCT/US2009/032830 WO2009102568A1 (en) 2008-02-13 2009-02-02 Conformationally restricted biphenyl derivatives for use as hepatitis c virus inhibitors

Publications (1)

Publication Number Publication Date
BRPI0908456A2 true BRPI0908456A2 (pt) 2019-09-24

Family

ID=40409903

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0908456A BRPI0908456A2 (pt) 2008-02-13 2009-02-02 derivados de bifenil restritos estruturalmente para uso como inibidores do vírus da hepatite c

Country Status (26)

Country Link
US (1) US7704992B2 (pt)
EP (1) EP2242750B1 (pt)
JP (1) JP5425815B2 (pt)
KR (1) KR101614964B1 (pt)
CN (1) CN101998954B (pt)
AR (1) AR070365A1 (pt)
AU (1) AU2009215105B2 (pt)
BR (1) BRPI0908456A2 (pt)
CA (1) CA2715550C (pt)
CL (1) CL2009000323A1 (pt)
CO (1) CO6251260A2 (pt)
CY (1) CY1114298T1 (pt)
DK (1) DK2242750T3 (pt)
EA (1) EA020511B1 (pt)
ES (1) ES2415208T3 (pt)
HR (1) HRP20130421T1 (pt)
IL (1) IL207258A0 (pt)
MX (1) MX2010008531A (pt)
NZ (1) NZ586990A (pt)
PE (1) PE20091575A1 (pt)
PL (1) PL2242750T3 (pt)
PT (1) PT2242750E (pt)
SI (1) SI2242750T1 (pt)
TW (1) TWI423798B (pt)
WO (1) WO2009102568A1 (pt)
ZA (1) ZA201005485B (pt)

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AU2009215105A1 (en) 2009-08-20
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US20090202483A1 (en) 2009-08-13
US7704992B2 (en) 2010-04-27
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