MA34147B1 - Composes tricycliques fusionnes de silyle et leurs methodes d'utilisation dans le cadre du traitement de maladies virales - Google Patents
Composes tricycliques fusionnes de silyle et leurs methodes d'utilisation dans le cadre du traitement de maladies viralesInfo
- Publication number
- MA34147B1 MA34147B1 MA35291A MA35291A MA34147B1 MA 34147 B1 MA34147 B1 MA 34147B1 MA 35291 A MA35291 A MA 35291A MA 35291 A MA35291 A MA 35291A MA 34147 B1 MA34147 B1 MA 34147B1
- Authority
- MA
- Morocco
- Prior art keywords
- silyl
- fusioned
- treatment
- methods
- tricyclic compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical class [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000003612 virological effect Effects 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
- C07F7/0816—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring said ring comprising Si as a ring atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/695—Silicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
LA PRÉSENTE INVENTION CONCERNE DES COMPOSÉS INÉDITS TRICYCLIQUES FUSIONNÉS DE SILYLE DE FORMULE (I), AINSI QUE LEURS SELS PHARMACEUTIQUEMENT ACCEPTABLES, FORMULE (I) DANS LAQUELLE A, B, C, D, M1, X1 ET X2 SONT TELS QUE DÉFINIS ICI. LA PRÉSENTE INVENTION CONCERNE ÉGALEMENT DES COMPOSITIONS CONTENANT AU MOINS UN COMPOSÉ TRICYCLIQUE FUSIONNÉ DE SILYLE, AINSI QUE DES MÉTHODES D'UTILISATION DESDITS COMPOSÉS TRICYCLIQUES FUSIONNÉS DE SILYLE EN VUE DU TRAITEMENT OU DE LA PRÉVENTION D'UNE INFECTION PAR LE VHC CHEZ UN PATIENT.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31201610P | 2010-03-09 | 2010-03-09 | |
| US37193510P | 2010-08-09 | 2010-08-09 | |
| PCT/US2011/027117 WO2011112429A1 (fr) | 2010-03-09 | 2011-03-04 | Composés tricycliques fusionnés de silyle et leurs méthodes d'utilisation dans le cadre du traitement de maladies virales |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA34147B1 true MA34147B1 (fr) | 2013-04-03 |
Family
ID=43939669
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA35291A MA34147B1 (fr) | 2010-03-09 | 2011-03-04 | Composes tricycliques fusionnes de silyle et leurs methodes d'utilisation dans le cadre du traitement de maladies virales |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US8609635B2 (fr) |
| EP (1) | EP2545060B1 (fr) |
| JP (1) | JP2013522202A (fr) |
| KR (1) | KR20130008040A (fr) |
| CN (1) | CN102918049A (fr) |
| AR (1) | AR080676A1 (fr) |
| AU (1) | AU2011224698A1 (fr) |
| BR (1) | BR112012022125A2 (fr) |
| CA (1) | CA2792121A1 (fr) |
| CL (1) | CL2012002489A1 (fr) |
| CO (1) | CO6592102A2 (fr) |
| CR (1) | CR20120460A (fr) |
| DO (1) | DOP2012000243A (fr) |
| EA (1) | EA201290882A1 (fr) |
| EC (1) | ECSP12012147A (fr) |
| ES (1) | ES2558554T3 (fr) |
| MA (1) | MA34147B1 (fr) |
| MX (1) | MX2012010392A (fr) |
| NI (1) | NI201200139A (fr) |
| PE (1) | PE20130062A1 (fr) |
| PH (1) | PH12012501748A1 (fr) |
| SG (1) | SG183526A1 (fr) |
| TN (1) | TN2012000416A1 (fr) |
| TW (1) | TW201136943A (fr) |
| WO (1) | WO2011112429A1 (fr) |
| ZA (1) | ZA201206716B (fr) |
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| RU2505539C2 (ru) | 2008-12-23 | 2014-01-27 | Эбботт Лэборетриз | Антивирусные соединения |
| CN102264737A (zh) * | 2008-12-23 | 2011-11-30 | 雅培制药有限公司 | 抗病毒化合物 |
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| HUE027755T2 (en) | 2009-03-27 | 2016-11-28 | Merck Sharp & Dohme | Inhibitors of hepatitis C virus replication |
| WO2010120935A1 (fr) | 2009-04-15 | 2010-10-21 | Abbott Laboratories | Composés antiviraux |
| AU2010249080A1 (en) | 2009-05-12 | 2012-01-12 | Merck Sharp & Dohme Corp. | Fused tricyclic aryl compounds useful for the treatment of viral diseases |
| SG176015A1 (en) | 2009-05-13 | 2011-12-29 | Gilead Sciences Inc | Antiviral compounds |
| JP2012528195A (ja) | 2009-05-29 | 2012-11-12 | メルク・シャープ・アンド・ドーム・コーポレーション | C型肝炎などの疾患を処置するための3つの結合アリール部分で構成された抗菌性化合物 |
| EP2435421A1 (fr) | 2009-05-29 | 2012-04-04 | Schering Corporation | Composés antiviraux constitués de trois fractions d'aryle alignées pour traiter des maladies telles que l'hépatite c |
| EP2853531A3 (fr) * | 2009-06-11 | 2015-08-12 | AbbVie Bahamas Ltd. | Composés antiviraux |
| US9394279B2 (en) | 2009-06-11 | 2016-07-19 | Abbvie Inc. | Anti-viral compounds |
| US8937150B2 (en) | 2009-06-11 | 2015-01-20 | Abbvie Inc. | Anti-viral compounds |
| US8716454B2 (en) | 2009-06-11 | 2014-05-06 | Abbvie Inc. | Solid compositions |
| US8354419B2 (en) | 2009-07-16 | 2013-01-15 | Vertex Pharmaceuticals Incorporated | Benzimidazole analogues for the treatment or prevention of flavivirus infections |
| WO2011087740A1 (fr) | 2009-12-22 | 2011-07-21 | Schering Corporation | Composés tricycliques fusionnés et leurs méthodes d'utilisation pour le traitement de maladies virales |
| MA34147B1 (fr) | 2010-03-09 | 2013-04-03 | Merck Sharp & Dohme | Composes tricycliques fusionnes de silyle et leurs methodes d'utilisation dans le cadre du traitement de maladies virales |
| WO2011119853A1 (fr) | 2010-03-24 | 2011-09-29 | Vertex Pharmaceuticals Incorporated | Analogues pour traiter ou prévenir les infections à flavivirus |
| NZ605440A (en) | 2010-06-10 | 2014-05-30 | Abbvie Bahamas Ltd | Solid compositions comprising an hcv inhibitor |
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| US9546160B2 (en) | 2011-05-12 | 2017-01-17 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
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| WO2013030750A1 (fr) | 2011-09-01 | 2013-03-07 | Lupin Limited | Composés antiviraux |
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| JP2020512331A (ja) * | 2017-03-22 | 2020-04-23 | 正大天晴▲藥▼▲業▼集▲団▼股▲フン▼有限公司 | 抗c型肝炎ウイルス感染のためのケイ素含有化合物 |
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-
2011
- 2011-03-04 MA MA35291A patent/MA34147B1/fr unknown
- 2011-03-04 MX MX2012010392A patent/MX2012010392A/es active IP Right Grant
- 2011-03-04 PE PE2012001466A patent/PE20130062A1/es not_active Application Discontinuation
- 2011-03-04 KR KR1020127026331A patent/KR20130008040A/ko not_active Ceased
- 2011-03-04 CN CN2011800233538A patent/CN102918049A/zh active Pending
- 2011-03-04 JP JP2012557114A patent/JP2013522202A/ja not_active Withdrawn
- 2011-03-04 AR ARP110100696A patent/AR080676A1/es unknown
- 2011-03-04 EP EP11707763.6A patent/EP2545060B1/fr active Active
- 2011-03-04 CA CA2792121A patent/CA2792121A1/fr not_active Abandoned
- 2011-03-04 SG SG2012063780A patent/SG183526A1/en unknown
- 2011-03-04 ES ES11707763.6T patent/ES2558554T3/es active Active
- 2011-03-04 BR BR112012022125A patent/BR112012022125A2/pt not_active IP Right Cessation
- 2011-03-04 EA EA201290882A patent/EA201290882A1/ru unknown
- 2011-03-04 WO PCT/US2011/027117 patent/WO2011112429A1/fr not_active Ceased
- 2011-03-04 US US13/041,082 patent/US8609635B2/en not_active Expired - Fee Related
- 2011-03-04 AU AU2011224698A patent/AU2011224698A1/en not_active Abandoned
- 2011-03-04 PH PH1/2012/501748A patent/PH12012501748A1/en unknown
- 2011-03-08 TW TW100107798A patent/TW201136943A/zh unknown
-
2012
- 2012-08-15 TN TNP2012000416A patent/TN2012000416A1/en unknown
- 2012-09-07 NI NI201200139A patent/NI201200139A/es unknown
- 2012-09-07 DO DO2012000243A patent/DOP2012000243A/es unknown
- 2012-09-07 ZA ZA2012/06716A patent/ZA201206716B/en unknown
- 2012-09-07 CL CL2012002489A patent/CL2012002489A1/es unknown
- 2012-09-10 EC ECSP12012147 patent/ECSP12012147A/es unknown
- 2012-09-10 CO CO12155041A patent/CO6592102A2/es not_active Application Discontinuation
- 2012-09-10 CR CR20120460A patent/CR20120460A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20130008040A (ko) | 2013-01-21 |
| EA201290882A1 (ru) | 2013-04-30 |
| EP2545060B1 (fr) | 2015-11-25 |
| JP2013522202A (ja) | 2013-06-13 |
| SG183526A1 (en) | 2012-09-27 |
| BR112012022125A2 (pt) | 2016-11-01 |
| PE20130062A1 (es) | 2013-02-28 |
| WO2011112429A1 (fr) | 2011-09-15 |
| ES2558554T3 (es) | 2016-02-05 |
| DOP2012000243A (es) | 2012-12-31 |
| TW201136943A (en) | 2011-11-01 |
| CL2012002489A1 (es) | 2012-11-30 |
| AU2011224698A1 (en) | 2012-11-01 |
| NI201200139A (es) | 2013-01-24 |
| ZA201206716B (en) | 2013-05-29 |
| AR080676A1 (es) | 2012-05-02 |
| TN2012000416A1 (en) | 2014-01-30 |
| MX2012010392A (es) | 2012-10-03 |
| US20110223134A1 (en) | 2011-09-15 |
| ECSP12012147A (es) | 2012-10-30 |
| PH12012501748A1 (en) | 2012-11-12 |
| CN102918049A (zh) | 2013-02-06 |
| US8609635B2 (en) | 2013-12-17 |
| CA2792121A1 (fr) | 2011-09-15 |
| EP2545060A1 (fr) | 2013-01-16 |
| CO6592102A2 (es) | 2013-01-02 |
| CR20120460A (es) | 2012-11-01 |
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