BRPI0909100A2 - Composição de cetorolaco de trometamina para tratar ou prevenir dor ocular - Google Patents

Composição de cetorolaco de trometamina para tratar ou prevenir dor ocular

Info

Publication number
BRPI0909100A2
BRPI0909100A2 BRPI0909100-9A BRPI0909100A BRPI0909100A2 BR PI0909100 A2 BRPI0909100 A2 BR PI0909100A2 BR PI0909100 A BRPI0909100 A BR PI0909100A BR PI0909100 A2 BRPI0909100 A2 BR PI0909100A2
Authority
BR
Brazil
Prior art keywords
treating
eye pain
preventing eye
tromethamine
ketorolac composition
Prior art date
Application number
BRPI0909100-9A
Other languages
English (en)
Inventor
Eldon Quinn Farnes
Mayssa Attar
Rhett M Schiffman
Chin-Ming Chang
Richard S Graham
Devin F Welty
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40852460&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0909100(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of BRPI0909100A2 publication Critical patent/BRPI0909100A2/pt
Publication of BRPI0909100B1 publication Critical patent/BRPI0909100B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BRPI0909100A 2008-03-03 2009-03-03 composições de cetorolaco de trometamina para tratar ou prevenir dor ocular BRPI0909100B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US6792508P 2008-03-03 2008-03-03
US9609608P 2008-09-11 2008-09-11
US11191908P 2008-11-06 2008-11-06
US12/396,131 US7842714B2 (en) 2008-03-03 2009-03-02 Ketorolac tromethamine compositions for treating ocular pain
PCT/US2009/035787 WO2009111418A2 (en) 2008-03-03 2009-03-03 Ketorolac tromethamine compositions for treating or preventing ocular pain

Publications (2)

Publication Number Publication Date
BRPI0909100A2 true BRPI0909100A2 (pt) 2015-08-11
BRPI0909100B1 BRPI0909100B1 (pt) 2019-01-15

Family

ID=40852460

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0909100A BRPI0909100B1 (pt) 2008-03-03 2009-03-03 composições de cetorolaco de trometamina para tratar ou prevenir dor ocular

Country Status (20)

Country Link
US (10) US7842714B2 (pt)
EP (2) EP2446878B1 (pt)
JP (1) JP5705552B2 (pt)
KR (1) KR101560429B1 (pt)
CN (1) CN102014869A (pt)
AT (1) ATE538775T1 (pt)
AU (1) AU2009222016B2 (pt)
BR (1) BRPI0909100B1 (pt)
CA (1) CA2717520C (pt)
CO (1) CO6321226A2 (pt)
DK (2) DK2257275T3 (pt)
ES (2) ES2382509T3 (pt)
HU (1) HUE027102T2 (pt)
IL (1) IL207925A (pt)
MX (1) MX2010009763A (pt)
MY (1) MY150250A (pt)
NZ (2) NZ602445A (pt)
PL (2) PL2446878T3 (pt)
WO (1) WO2009111418A2 (pt)
ZA (1) ZA201006372B (pt)

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US7842714B2 (en) * 2008-03-03 2010-11-30 Allergan, Inc. Ketorolac tromethamine compositions for treating ocular pain
AU2011237646A1 (en) * 2010-04-09 2012-11-08 Allergan, Inc. Ketorolac compositions for corneal wound healing
WO2013085769A1 (en) * 2011-12-06 2013-06-13 Alcon Research, Ltd. Cellulosic gel composition with improved viscosity stability
AU2013201465B2 (en) 2012-10-24 2016-03-03 Rayner Intraocular Lenses Limited Stable preservative-free mydriatic and anti-inflammatory solutions for injection
DE102013006596A1 (de) * 2013-04-17 2014-10-23 Jaime Guardiola Verfahren zum Herstellen einer sterilen intraokularen Spül-Lösung und Spül-Lösung
US20150164882A1 (en) 2013-07-22 2015-06-18 Imprimis Pharmaceuticals, Inc. Pharmaceutical compositions for intraocular administration and methods for fabricating thereof
US20160279055A1 (en) 2013-07-22 2016-09-29 Imprimis Pharmaceuticals, Inc. Pharmaceutical ophthalmic compositions for intraocular administration and methods for fabricating thereof
US20150335704A1 (en) 2014-05-23 2015-11-26 Imprimis Pharmaceuticals, Inc. Pharmaceutical compositions comprising gels and methods for fabricating thereof
TWI705812B (zh) 2014-12-01 2020-10-01 奥默羅斯公司 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液
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DK3870170T3 (da) 2018-10-26 2026-05-26 Opus Genetics Inc Behandling af presbyopi og mydriasis med fentolamin
US20200170998A1 (en) * 2018-11-29 2020-06-04 Cellula Llc Umbilical cord blood serum and umbilical cord blood plasma preparation in combination with a nonsteroidal anti-inflammatory drug and freeze-drying the composition
US20220411482A1 (en) 2019-11-15 2022-12-29 Silk Technologies, Ltd. Stable formulations of silk-derived protein

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Also Published As

Publication number Publication date
US20090326034A1 (en) 2009-12-31
HK1149212A1 (en) 2011-09-30
CN102014869A (zh) 2011-04-13
JP2011513416A (ja) 2011-04-28
EP2257275A2 (en) 2010-12-08
DK2257275T3 (da) 2012-04-02
WO2009111418A3 (en) 2010-04-01
EP2446878A1 (en) 2012-05-02
PL2446878T3 (pl) 2016-06-30
EP2446878B1 (en) 2015-12-30
CA2717520A1 (en) 2009-09-11
US20250281432A1 (en) 2025-09-11
IL207925A0 (en) 2010-12-30
US20110160271A1 (en) 2011-06-30
AU2009222016A1 (en) 2009-09-11
US20200197336A1 (en) 2020-06-25
BRPI0909100B1 (pt) 2019-01-15
NZ602445A (en) 2014-06-27
WO2009111418A2 (en) 2009-09-11
ATE538775T1 (de) 2012-01-15
US20230181497A1 (en) 2023-06-15
ES2566162T3 (es) 2016-04-11
US20110275688A1 (en) 2011-11-10
US20240197657A1 (en) 2024-06-20
MX2010009763A (es) 2010-12-07
CA2717520C (en) 2012-05-01
AU2009222016B2 (en) 2014-09-04
KR101560429B1 (ko) 2015-10-15
JP5705552B2 (ja) 2015-04-22
US7842714B2 (en) 2010-11-30
ES2382509T3 (es) 2012-06-08
US20120196913A1 (en) 2012-08-02
DK2446878T3 (en) 2016-04-04
HUE027102T2 (en) 2016-08-29
ZA201006372B (en) 2011-05-25
KR20100130989A (ko) 2010-12-14
IL207925A (en) 2015-03-31
CO6321226A2 (es) 2011-09-20
US20120196914A1 (en) 2012-08-02
EP2257275B1 (en) 2011-12-28
MY150250A (en) 2013-12-31
US20110046198A1 (en) 2011-02-24
PL2257275T3 (pl) 2012-05-31
NZ588367A (en) 2013-03-28

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