BRPI0909945A2 - "composto, composição farmacêutica, método para tratar ou atenuar a gravidade de uma doença ou condição responsiva à inibição da atividade jak2 quinase em um paciente, kit para o tratamento de uma doença ou distúrbio responsivo à inibição da jak quinase" - Google Patents

"composto, composição farmacêutica, método para tratar ou atenuar a gravidade de uma doença ou condição responsiva à inibição da atividade jak2 quinase em um paciente, kit para o tratamento de uma doença ou distúrbio responsivo à inibição da jak quinase"

Info

Publication number: BRPI0909945A2
Authority: BR; Brazil
Prior art keywords: inhibition; disease; treating; responsive; alleviating
Prior art date: 2008-06-20

Application number

BRPI0909945-0A

Other languages

English (en)

Inventor

Bing-Yan Zhu

He Haiying

Michael Siu

Richard Pastor

Steven R Magnuson

Wendy Liu

Xiao Yisong

Xu Xing

Zhao Junping

Zheng Jifu

Original Assignee

Genentech Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-06-20

Filing date

2009-06-19

Publication date

2015-07-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41434472&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0909945(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-06-19 Application filed by Genentech Inc filed Critical Genentech Inc

2015-07-28 Publication of BRPI0909945A2 publication Critical patent/BRPI0909945A2/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
- A—HUMAN NECESSITIES
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Immunology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Neurosurgery (AREA)
Physical Education & Sports Medicine (AREA)
Hematology (AREA)
Cardiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Oncology (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Communicable Diseases (AREA)
Emergency Medicine (AREA)
Psychiatry (AREA)
Virology (AREA)
Transplantation (AREA)

BRPI0909945-0A 2008-06-20 2009-06-19 "composto, composição farmacêutica, método para tratar ou atenuar a gravidade de uma doença ou condição responsiva à inibição da atividade jak2 quinase em um paciente, kit para o tratamento de uma doença ou distúrbio responsivo à inibição da jak quinase" BRPI0909945A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US7451008P	2008-06-20	2008-06-20
PCT/US2009/048041 WO2009155565A1 (en)	2008-06-20	2009-06-19	Triazolopyridine jak inhibitor compounds and methods

Publications (1)

Publication Number	Publication Date
BRPI0909945A2 true BRPI0909945A2 (pt)	2015-07-28

Family

ID=41434472

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0909945-0A BRPI0909945A2 (pt)	2008-06-20	2009-06-19	"composto, composição farmacêutica, método para tratar ou atenuar a gravidade de uma doença ou condição responsiva à inibição da atividade jak2 quinase em um paciente, kit para o tratamento de uma doença ou distúrbio responsivo à inibição da jak quinase"

Country Status (15)

Country	Link
US (4)	US20100035875A1 (pt)
EP (1)	EP2296475A4 (pt)
JP (1)	JP5595389B2 (pt)
KR (1)	KR20110031475A (pt)
CN (1)	CN102131390A (pt)
AU (1)	AU2009259867A1 (pt)
BR (1)	BRPI0909945A2 (pt)
CA (1)	CA2726844C (pt)
CL (1)	CL2010001486A1 (pt)
IL (1)	IL209764A0 (pt)
MX (1)	MX336271B (pt)
PE (1)	PE20110063A1 (pt)
RU (1)	RU2561104C2 (pt)
SG (1)	SG178807A1 (pt)
WO (1)	WO2009155565A1 (pt)

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* Cited by examiner, † Cited by third party
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GB0719803D0 (en)	2007-10-10	2007-11-21	Cancer Rec Tech Ltd	Therapeutic compounds and their use
US9156812B2 (en)	2008-06-04	2015-10-13	Bristol-Myers Squibb Company	Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
US20100035875A1 (en)	2008-06-20	2010-02-11	Bing-Yan Zhu	Triazolopyridine jak inhibitor compounds and methods
KR20110033223A (ko) *	2008-06-20	2011-03-30	제넨테크, 인크.	트리아졸로피리딘 ｊａｋ 억제제 화합물 및 방법
JO3041B1 (ar)	2008-07-25	2016-09-05	Galapagos Nv	مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية
TWI453207B (zh) *	2008-09-08	2014-09-21	Signal Pharm Llc	胺基三唑并吡啶，其組合物及使用其之治療方法
AU2011211410B2 (en) *	2009-02-13	2013-01-31	Fovea Pharmaceuticals Sa	[1,2,4] triazolo [1,5-A] pyridines as kinase inhibitors
CN102317288A (zh) *	2009-02-13	2012-01-11	佛维雅制药公司	作为激酶抑制剂的[1,2,4]三唑并[1,5-a]吡啶
WO2010132487A1 (en)	2009-05-12	2010-11-18	Bristol-Myers Squibb Company	CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF
CN102458123A (zh)	2009-05-12	2012-05-16	阿尔巴尼分子研究公司	芳基、杂芳基和杂环取代的四氢异喹啉及其用途
US8802696B2 (en)	2009-05-12	2014-08-12	Albany Molecular Research, Inc.	7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoqu inoli and use thereof
NZ597140A (en)	2009-06-05	2014-01-31	Cephalon Inc	Preparation and uses of 1,2,4-triazolo [1,5a] pyridine derivatives
JO3030B1 (ar)	2009-06-26	2016-09-05	Galapagos Nv	مركب جديد مفيد لمعالجة الامراض التنكسية والالتهابات
TWI462920B (zh)	2009-06-26	2014-12-01	葛萊伯格有限公司	用於治療退化性及發炎疾病之新穎化合物
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2009
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- 2009-06-19 MX MX2010014002A patent/MX336271B/es unknown
- 2009-06-19 EP EP09767873.4A patent/EP2296475A4/en not_active Withdrawn
- 2009-06-19 BR BRPI0909945-0A patent/BRPI0909945A2/pt not_active IP Right Cessation
- 2009-06-19 CA CA2726844A patent/CA2726844C/en not_active Expired - Fee Related
- 2009-06-19 WO PCT/US2009/048041 patent/WO2009155565A1/en not_active Ceased
- 2009-06-19 CN CN200980132602XA patent/CN102131390A/zh active Pending
- 2009-06-19 KR KR1020117001402A patent/KR20110031475A/ko not_active Ceased
- 2009-06-19 AU AU2009259867A patent/AU2009259867A1/en not_active Abandoned
- 2009-06-19 PE PE2010001174A patent/PE20110063A1/es not_active Application Discontinuation
- 2009-06-19 JP JP2011514866A patent/JP5595389B2/ja not_active Expired - Fee Related
- 2009-06-19 RU RU2011101901/04A patent/RU2561104C2/ru not_active IP Right Cessation
- 2009-06-19 SG SG2012012076A patent/SG178807A1/en unknown
2010
- 2010-12-05 IL IL209764A patent/IL209764A0/en unknown
- 2010-12-20 CL CL2010001486A patent/CL2010001486A1/es unknown
2012
- 2012-06-21 US US13/529,946 patent/US8889673B2/en not_active Expired - Fee Related
2014
- 2014-09-11 US US14/483,485 patent/US20140378449A1/en not_active Abandoned
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- 2015-10-08 US US14/878,774 patent/US20160024089A1/en not_active Abandoned

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KR20110031475A (ko)	2011-03-28
PE20110063A1 (es)	2011-02-16
EP2296475A4 (en)	2014-03-05
WO2009155565A1 (en)	2009-12-23
IL209764A0 (en)	2011-02-28
US8889673B2 (en)	2014-11-18
US20140378449A1 (en)	2014-12-25
CA2726844A1 (en)	2009-12-23
US20160024089A1 (en)	2016-01-28
CN102131390A (zh)	2011-07-20
CA2726844C (en)	2016-08-30
EP2296475A1 (en)	2011-03-23
AU2009259867A1 (en)	2009-12-23
JP5595389B2 (ja)	2014-09-24
CL2010001486A1 (es)	2011-05-06
MX2010014002A (es)	2011-02-15
US20100035875A1 (en)	2010-02-11
JP2011525193A (ja)	2011-09-15
RU2561104C2 (ru)	2015-08-20
RU2011101901A (ru)	2012-07-27
US20120264747A1 (en)	2012-10-18
SG178807A1 (en)	2012-03-29
MX336271B (es)	2016-01-13

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BRPI0819799A2 (pt)	2015-05-26	Composto, intermediário, uso de um composto, composição farmacêutica, e, método para prevenir, tratar ou melhorar uma doença
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BR112012003464A2 (pt)	2015-09-08	composto, composição farmacêutica, usos de uma composição farmacêutica e de um composto, e, método para tratar uma doença ou um distúrbio."
BRPI0818799A2 (pt)	2015-04-22	Composições para o tratamento da doença de parkinson
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BRPI0819755A2 (pt)	2018-07-17	composto, composição farmacêutica, processos para a preparação de um composto e de uma composição farmacêutica, uso de um composto, e, método para tratar ou reduzir o risco de uma doença ou uma condição inflamatória
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BRPI0913585A2 (pt)	2015-10-27	composto, método para fabricar um composto, composição farmacêutica, uso de um composto, e, método para o tratamento ou prevenção de distúrbios
BRPI0915084A2 (pt)	2015-10-27	composto, processo para a preparação de um composto, composição farmacêutica, uso de um composto, métodos para a profilaxia ou tratamento de um estado de doença ou uma condição e de câncer
BRPI1009022A2 (pt)	2016-03-08	"composto, composição farmacêutica, processo para produzir uma composição farmacêutica, uso de um composto, método para tratamento de uma doença ou transtorno e kit"