BRPI0807749A2 - Composto, composição farmacêutica, e, método para a prevenção, tratamento ou melhora de doenças ou condições dérmicas, ou distúrbios de ferida cutânea agudos ou crônicos. - Google Patents

Composto, composição farmacêutica, e, método para a prevenção, tratamento ou melhora de doenças ou condições dérmicas, ou distúrbios de ferida cutânea agudos ou crônicos.

Info

Publication number: BRPI0807749A2
Authority: BR; Brazil
Prior art keywords: cutaneal; chronic; acute; prevention; improvement
Prior art date: 2007-02-28

Application number

BRPI0807749-5A2A

Other languages

English (en)

Inventor

Jakob Felding

Simon Feldbaek Nielsen

Jens Christian Hojland Larsen

Bollu Ravindra Babu

Original Assignee

Leo Pharma As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-02-28

Filing date

2008-02-26

Publication date

2014-06-17

2008-02-26 Application filed by Leo Pharma As filed Critical Leo Pharma As

2014-06-17 Publication of BRPI0807749A2 publication Critical patent/BRPI0807749A2/pt

2021-01-05 Publication of BRPI0807749B1 publication Critical patent/BRPI0807749B1/pt

2022-09-06 Publication of BRPI0807749B8 publication Critical patent/BRPI0807749B8/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Dermatology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

BRPI0807749A 2007-02-28 2008-02-26 composto, composição farmacêutica, e, método para a prevenção, tratamento ou melhora de doenças ou condições dérmicas, ou distúrbios de ferida cutânea agudos ou crônicos BRPI0807749B8 (pt)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US90384907P	2007-02-28	2007-02-28
US60/903849		2007-02-28
US94684907P	2007-06-28	2007-06-28
US60/946849		2007-06-28
PCT/DK2008/000080 WO2008104175A2 (en)	2007-02-28	2008-02-26	Novel phosphodiesterase inhibitors

Publications (3)

Publication Number	Publication Date
BRPI0807749A2 true BRPI0807749A2 (pt)	2014-06-17
BRPI0807749B1 BRPI0807749B1 (pt)	2021-01-05
BRPI0807749B8 BRPI0807749B8 (pt)	2022-09-06

Family

ID=39415336

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0807749A BRPI0807749B8 (pt)	2007-02-28	2008-02-26	composto, composição farmacêutica, e, método para a prevenção, tratamento ou melhora de doenças ou condições dérmicas, ou distúrbios de ferida cutânea agudos ou crônicos

Country Status (21)

Country	Link
US (1)	US8338431B2 (pt)
EP (1)	EP2114951B9 (pt)
JP (1)	JP5501770B2 (pt)
KR (1)	KR101571654B1 (pt)
AU (1)	AU2008221121B2 (pt)
BR (1)	BRPI0807749B8 (pt)
CA (1)	CA2676933C (pt)
CY (1)	CY1115227T1 (pt)
DK (1)	DK2114951T3 (pt)
ES (1)	ES2478670T3 (pt)
HR (1)	HRP20140585T1 (pt)
IL (1)	IL200153A (pt)
MX (1)	MX2009009238A (pt)
MY (1)	MY150075A (pt)
NZ (1)	NZ578804A (pt)
PL (1)	PL2114951T3 (pt)
PT (1)	PT2114951E (pt)
RS (1)	RS53407B (pt)
RU (1)	RU2495043C2 (pt)
SI (1)	SI2114951T1 (pt)
WO (1)	WO2008104175A2 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20120322776A1 (en)	2009-12-22	2012-12-20	Leo Pharma A/S	Cutaneous composition comprising vitamin d analogue and a mixture of solvent and surfactants
RU2555339C2 (ru)	2009-12-22	2015-07-10	Лео Фарма А/С	Нанокристаллы кальципотриола моногидрита
JP5732471B2 (ja)	2009-12-22	2015-06-10	レオファーマアクティーゼルスカブ	溶媒混合物およびビタミンｄ誘導体から成る医薬品組成物または類似体
KR101864578B1 (ko) *	2010-06-24	2018-06-07	레오 파마 에이/에스	포스포디에스테라제 억제제로서의 벤조디옥솔 또는 벤조디옥세핀 헤테로사이클릭 화합물
WO2013122855A1 (en) *	2012-02-14	2013-08-22	University Of Rochester	Methods of increasing lymphatic transport
CN104334542A (zh) *	2012-06-04	2015-02-04	奇斯药制品公司	作为磷酸二酯酶抑制剂的1-苯基-2-吡啶基烷基醇的衍生物
WO2014083099A1 (en) *	2012-11-30	2014-06-05	Leo Pharma A/S	A method of inhibiting the expression of il-22 in activated t-cells
AU2015279428B2 (en) *	2014-06-23	2018-02-15	Leo Pharma A/S	Methods for the preparation of 1,3-benzodioxole heterocyclic compounds
ES2762987T3 (es)	2015-06-19	2020-05-26	Bristol Myers Squibb Co	Macrociclos de diamida como inhibidores del factor XIA
TWI732808B (zh)	2015-12-18	2021-07-11	丹麥商理奧藥品公司	1,3－苯并二氧雜環戊烯雜環化合物之製備方法
JP6850886B2 (ja) *	2016-12-12	2021-03-31	レオファーマアクティーゼルスカブ	置換ピラゾロアゼピン−４−オンおよびそれらのホスホジエステラーゼ阻害剤としての使用
ES2874632T3 (es) *	2016-12-12	2021-11-05	Union Therapeutics As	Pirazoloazepin-8-onas sustituidas y su uso como inhibidores de la fosfodiesterasa
EP3551632B1 (en) *	2016-12-12	2024-06-12	UNION therapeutics A/S	Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors
WO2018234299A1 (en) *	2017-06-20	2018-12-27	Leo Pharma A/S	Methods for the preparation of 1,3-benzodioxole heterocyclic compounds
TW201919682A (zh)	2017-08-08	2019-06-01	西班牙商阿爾米雷爾有限公司	活化Ｎｒｆ２路徑的新穎化合物
ES2935615T3 (es)	2017-12-15	2023-03-08	Union Therapeutics As	Azetidina dihidrotienopiridinas sustituidas y su uso como inhibidores de la fosfodiesterasa
GB202306662D0 (en)	2023-05-05	2023-06-21	Union Therapeutics As	Dosage regimen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9507297D0 (en)	1995-04-07	1995-05-31	Rh Ne Poulenc Rorer Limited	New composition of matter
US6514996B2 (en) *	1995-05-19	2003-02-04	Kyowa Hakko Kogyo Co., Ltd.	Derivatives of benzofuran or benzodioxole
DK0771794T3 (da) *	1995-05-19	2006-09-11	Kyowa Hakko Kogyo Kk	Oxygenholdige heterocykliske forbindelser
ATE239004T1 (de) *	1996-05-20	2003-05-15	Darwin Discovery Ltd	Benzofuran carboxamide und ihre therapeutische anwendung
RU2203274C2 (ru) *	1996-08-28	2003-04-27	Дзе Проктер Энд Гэмбл Компани	Спироциклические ингибиторы металлопротеаз
EP0943613A4 (en) *	1996-11-19	2002-07-10	Kyowa Hakko Kogyo Kk	Oxygenic heterocyclic compounds
DE69813605T2 (de) *	1997-10-01	2004-02-12	Kyowa Hakko Kogyo Co., Ltd.	Benzofuranderivate

2008
- 2008-02-26 RS RS20140365A patent/RS53407B/sr unknown
- 2008-02-26 JP JP2009551915A patent/JP5501770B2/ja not_active Expired - Fee Related
- 2008-02-26 KR KR1020097018073A patent/KR101571654B1/ko active Active
- 2008-02-26 PT PT87069225T patent/PT2114951E/pt unknown
- 2008-02-26 DK DK08706922.5T patent/DK2114951T3/da active
- 2008-02-26 US US12/528,649 patent/US8338431B2/en active Active
- 2008-02-26 NZ NZ578804A patent/NZ578804A/en not_active IP Right Cessation
- 2008-02-26 BR BRPI0807749A patent/BRPI0807749B8/pt not_active IP Right Cessation
- 2008-02-26 MY MYPI20093168A patent/MY150075A/en unknown
- 2008-02-26 ES ES08706922.5T patent/ES2478670T3/es active Active
- 2008-02-26 RU RU2009135810/04A patent/RU2495043C2/ru active
- 2008-02-26 AU AU2008221121A patent/AU2008221121B2/en not_active Ceased
- 2008-02-26 HR HRP20140585AT patent/HRP20140585T1/hr unknown
- 2008-02-26 CA CA2676933A patent/CA2676933C/en active Active
- 2008-02-26 EP EP08706922.5A patent/EP2114951B9/en active Active
- 2008-02-26 MX MX2009009238A patent/MX2009009238A/es active IP Right Grant
- 2008-02-26 WO PCT/DK2008/000080 patent/WO2008104175A2/en not_active Ceased
- 2008-02-26 PL PL08706922T patent/PL2114951T3/pl unknown
- 2008-02-26 SI SI200831224T patent/SI2114951T1/sl unknown
2009
- 2009-07-30 IL IL200153A patent/IL200153A/en active IP Right Grant
2014
- 2014-06-17 CY CY20141100437T patent/CY1115227T1/el unknown

Also Published As

Publication number	Publication date
MX2009009238A (es)	2009-09-08
EP2114951B9 (en)	2015-09-02
SI2114951T1 (sl)	2014-08-29
KR101571654B1 (ko)	2015-11-25
DK2114951T3 (da)	2014-06-23
PT2114951E (pt)	2014-07-17
EP2114951A2 (en)	2009-11-11
JP5501770B2 (ja)	2014-05-28
HRP20140585T1 (hr)	2014-09-12
KR20090126252A (ko)	2009-12-08
WO2008104175A2 (en)	2008-09-04
AU2008221121A1 (en)	2008-09-04
US8338431B2 (en)	2012-12-25
CY1115227T1 (el)	2017-01-04
EP2114951B1 (en)	2014-04-09
AU2008221121B2 (en)	2013-10-03
MY150075A (en)	2013-11-29
IL200153A (en)	2016-11-30
IL200153A0 (en)	2010-04-15
NZ578804A (en)	2012-04-27
RU2009135810A (ru)	2011-04-10
RU2495043C2 (ru)	2013-10-10
PL2114951T3 (pl)	2014-10-31
RS53407B (sr)	2014-10-31
JP2010519332A (ja)	2010-06-03
HK1138262A1 (en)	2010-08-20
BRPI0807749B8 (pt)	2022-09-06
CA2676933A1 (en)	2008-09-04
ES2478670T3 (es)	2014-07-22
US20100099688A1 (en)	2010-04-22
WO2008104175A3 (en)	2009-01-29
CA2676933C (en)	2015-09-29
BRPI0807749B1 (pt)	2021-01-05

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Legal Events

Date	Code	Title	Description
2018-03-20	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]	Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.
2018-04-24	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2020-01-28	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
2020-02-11	B06U	Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
2020-07-14	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2020-11-17	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2021-01-05	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 05/01/2021, OBSERVADAS AS CONDICOES LEGAIS.
2021-05-25	B16C	Correction of notification of the grant [chapter 16.3 patent gazette]	Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 26/02/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF
2022-03-15	B25A	Requested transfer of rights approved	Owner name: UNION THERAPEUTICS A/S (DK)
2022-08-23	B25L	Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled	Owner name: LEO PHARMA A/S (DK) Free format text: ANULADA A PUBLICACAO CODIGO 25.1 NA RPI NO 2671 DE 15/03/2022 POR TER SIDO INDEVIDA.
2022-09-06	B25A	Requested transfer of rights approved	Owner name: UNION THERAPEUTICS A/S (DK)
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