BRPI0911847A2 - composições de pastilhas de nicotina - Google Patents

composições de pastilhas de nicotina

Info

Publication number
BRPI0911847A2
BRPI0911847A2 BRPI0911847A BRPI0911847A BRPI0911847A2 BR PI0911847 A2 BRPI0911847 A2 BR PI0911847A2 BR PI0911847 A BRPI0911847 A BR PI0911847A BR PI0911847 A BRPI0911847 A BR PI0911847A BR PI0911847 A2 BRPI0911847 A2 BR PI0911847A2
Authority
BR
Brazil
Prior art keywords
tablet compositions
nicotine tablet
nicotine
compositions
tablet
Prior art date
Application number
BRPI0911847A
Other languages
English (en)
Inventor
Li-Lan Chen
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41255405&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0911847(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of BRPI0911847A2 publication Critical patent/BRPI0911847A2/pt
Publication of BRPI0911847A8 publication Critical patent/BRPI0911847A8/pt
Publication of BRPI0911847B1 publication Critical patent/BRPI0911847B1/pt
Publication of BRPI0911847B8 publication Critical patent/BRPI0911847B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465Nicotine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Addiction (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacture Of Tobacco Products (AREA)
BRPI0911847A 2008-05-01 2009-04-30 composições de pastilha de nicotina BRPI0911847B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4951508P 2008-05-01 2008-05-01
US61/049.515 2008-05-01
PCT/US2009/042190 WO2009134947A1 (en) 2008-05-01 2009-04-30 Nicotine lozenge compositions

Publications (4)

Publication Number Publication Date
BRPI0911847A2 true BRPI0911847A2 (pt) 2015-10-06
BRPI0911847A8 BRPI0911847A8 (pt) 2018-03-06
BRPI0911847B1 BRPI0911847B1 (pt) 2021-04-13
BRPI0911847B8 BRPI0911847B8 (pt) 2021-05-25

Family

ID=41255405

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0911847A BRPI0911847B8 (pt) 2008-05-01 2009-04-30 composições de pastilha de nicotina

Country Status (18)

Country Link
US (3) US8501164B2 (pt)
EP (1) EP2285411B1 (pt)
JP (2) JP5893405B2 (pt)
CN (1) CN102076362B (pt)
AR (1) AR071420A1 (pt)
AU (1) AU2009243065B2 (pt)
BR (1) BRPI0911847B8 (pt)
CA (1) CA2723011A1 (pt)
CL (1) CL2009001025A1 (pt)
DK (1) DK2285411T3 (pt)
ES (1) ES2605244T3 (pt)
HU (1) HUE031175T2 (pt)
MX (1) MX2010011929A (pt)
MY (1) MY164646A (pt)
PL (1) PL2285411T3 (pt)
PT (1) PT2285411T (pt)
RU (1) RU2458692C2 (pt)
WO (1) WO2009134947A1 (pt)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112012020731A2 (pt) 2010-02-18 2016-04-26 Jatin Vasant Thakkar pastilhas gelatinosas suaves com nicotina.
UA112974C2 (uk) 2010-09-16 2016-11-25 Джеі. Бі. Кемікалс Енд Фармасьютікалс Лімітид Нікотиновмісна композиція (варіанти)
US9474303B2 (en) 2011-09-22 2016-10-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9629392B2 (en) 2011-09-22 2017-04-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9084439B2 (en) 2011-09-22 2015-07-21 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9763928B2 (en) 2012-02-10 2017-09-19 Niconovum Usa, Inc. Multi-layer nicotine-containing pharmaceutical composition
US9044035B2 (en) 2012-04-17 2015-06-02 R.J. Reynolds Tobacco Company Remelted ingestible products
TW201507726A (zh) * 2013-05-10 2015-03-01 Glaxosmithkline Llc 菸鹼菱形錠配製物
US12274276B2 (en) 2013-10-03 2025-04-15 Altria Client Services Llc Dissolvable-chewable tablet
US10244786B2 (en) 2013-10-03 2019-04-02 Altria Client Services Llc Tobacco lozenge
US11779045B2 (en) 2013-10-03 2023-10-10 Altria Client Services Llc Dissolvable-chewable exhausted-tobacco tablet
US9999243B2 (en) * 2013-10-03 2018-06-19 Altria Client Services Llc Exhausted tobacco lozenge
US9351936B2 (en) 2013-10-03 2016-05-31 Altria Client Services Llc Nicotine lozenge
US10105320B2 (en) 2013-10-03 2018-10-23 Altria Client Services Soluble fiber lozenge
EP3052081B1 (en) 2013-10-03 2020-12-09 Altria Client Services LLC Lozenge
US20170172995A1 (en) * 2015-09-08 2017-06-22 Venkateswara Rao Repaka Pharmaceutical compositions of Nicotine and process for preparation thereof
US11311623B2 (en) 2016-04-21 2022-04-26 Fertin Pharma A/S Nicotine delivery product, related uses and oral dosage forms, and methods of production
EP3720498A1 (en) * 2017-12-08 2020-10-14 Fertin Pharma A/S High nicotine absorption
CA3085065C (en) 2017-12-08 2023-12-05 Fertin Pharma A/S Formulations providing high nicotine concentrations
FI3720496T3 (fi) * 2017-12-08 2025-03-05 Fertin Pharma As Kiinteä suun kautta otettava nikotiiniformulaatio
CN111447921B (zh) 2017-12-08 2023-10-13 费尔廷制药公司 烟碱片剂
CA3040547C (en) 2019-04-17 2021-12-07 Medcan Pharma A/S Cannabinoid lozenge formulation
US11759419B2 (en) * 2019-10-11 2023-09-19 Fertin Pharma A/S Compressed nicotine lozenge
US11000540B1 (en) * 2019-11-22 2021-05-11 Al Siamon Treatment for reducing adverse events including chemotherapy discomfort and other conditions
US11793230B2 (en) 2019-12-09 2023-10-24 Nicoventures Trading Limited Oral products with improved binding of active ingredients
US20230053622A1 (en) * 2020-01-15 2023-02-23 Mcneil Ab Lozenge
USD1081739S1 (en) 2021-04-06 2025-07-01 Altria Client Services Llc Die for gum forming
US20220387328A1 (en) 2021-06-04 2022-12-08 Glaxosmithkline Consumer Healthcare Holdings (Us) Llc Dosage form for nicotine replacement therapy
MX2024003997A (es) * 2021-09-30 2024-06-04 Nicoventures Trading Ltd Composicion de goma oral.
US12295412B2 (en) 2022-01-28 2025-05-13 Altria Client Services Llc Oral pouch product
CN115813007B (zh) * 2022-12-22 2025-02-14 东莞市吉纯生物技术有限公司 尼古丁口含制品及制备方法和碱性电解水的制备方法
DK182273B1 (en) * 2023-07-07 2026-01-30 Fertin Pharma As Dissolvable orally adhering nicotine tablet
DK182278B1 (en) * 2023-07-07 2026-02-04 Fertin Pharma As Dissolvable orally adhering tablet

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863737A (en) 1985-05-01 1989-09-05 University Of Utah Compositions and methods of manufacture of compressed powder medicaments
GB8615676D0 (en) * 1986-06-26 1986-07-30 Stoppers Co Ltd Nicotine containing lozenge
US5135753A (en) * 1991-03-12 1992-08-04 Pharmetrix Corporation Method and therapeutic system for smoking cessation
US5549906A (en) 1993-07-26 1996-08-27 Pharmacia Ab Nicotine lozenge and therapeutic method for smoking cessation
PT906089E (pt) 1996-05-13 2004-01-30 Novartis Consumer Health Sa Sistema de administracao bucal
EP2158903A3 (en) 1998-12-18 2010-04-14 ALZA Corporation Transparent Transdermal Nicotine Delivery Devices
FR2792200B3 (fr) 1999-04-16 2001-06-08 Unicliffe Ltd Substitut du tabac sous forme d'un comprime ou d'une pastille a sucer
EP1389910A4 (en) * 2001-04-20 2005-11-02 Lavipharm Lab Inc INTRABUCAL DISTRIBUTION OF NICOTINE INTENDED TO STOP SMOKING
SE0102197D0 (sv) 2001-06-20 2001-06-20 Pharmacia Ab New product and use and manufacture thereof
AU2002358270A1 (en) * 2001-12-20 2003-07-09 Pharmacia Corporation Zero-order sustained released dosage forms and method of making the same
US7767698B2 (en) 2002-06-03 2010-08-03 Mcneil Ab Formulation and use thereof
US20040052851A1 (en) * 2002-09-16 2004-03-18 Graff Allan H. Modified release oral dosage form
ES2285233T3 (es) * 2002-12-20 2007-11-16 Niconovum Ab Un material en particulas que contiene nicotina y celulosa microcristalina fisicamente y quimicamente estable.
US20040182403A1 (en) 2003-02-28 2004-09-23 Sven-Borje Andersson Container comprising nicotine and the use and manufacture thereof
GB0320854D0 (en) 2003-09-05 2003-10-08 Arrow No 7 Ltd Buccal drug delivery
DK1663168T3 (da) 2003-09-08 2009-06-08 Mcneil Ab Nikotinformuleringer og anvendelse deraf
US20050123502A1 (en) * 2003-10-07 2005-06-09 Chan Shing Y. Nicotine containing oral compositions
US8323683B2 (en) 2005-05-18 2012-12-04 Mcneil-Ppc, Inc. Flavoring of drug-containing chewing gums
WO2007104574A2 (en) 2006-03-16 2007-09-20 Niconovum Ab Chewing gum compositions providing rapid release of nicotine
US20070269492A1 (en) * 2006-05-16 2007-11-22 Per Steen New product and use and manufacture thereof
US20070269386A1 (en) 2006-05-16 2007-11-22 Per Steen New product and use and manufacture thereof
US20080286341A1 (en) 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered coated nicotine containing products
US20080287507A1 (en) 2007-05-16 2008-11-20 John Hedenstrom Nicotine containing toiletry waters
US20080286340A1 (en) 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered nicotine containing products
US20090004248A1 (en) 2007-06-29 2009-01-01 Frank Bunick Dual portion dosage lozenge form
US20090164008A1 (en) * 2007-12-21 2009-06-25 Xin Hong Lens surface with combined diffractive, toric, and aspheric components
JP2012505878A (ja) 2008-10-14 2012-03-08 マクニール アーベー 複数部分口内剤形及びその使用
EP2233134A1 (en) 2009-03-27 2010-09-29 McNeil AB Multi-portion intra-oral dosage form with organoleptic properties
US8871263B2 (en) 2009-09-24 2014-10-28 Mcneil-Ppc, Inc. Manufacture of tablet in a die utilizing radiofrequency energy and meltable binder

Also Published As

Publication number Publication date
RU2458692C2 (ru) 2012-08-20
US20110110880A1 (en) 2011-05-12
EP2285411A4 (en) 2011-05-18
WO2009134947A1 (en) 2009-11-05
ES2605244T3 (es) 2017-03-13
JP5893405B2 (ja) 2016-03-23
AU2009243065B2 (en) 2013-05-23
CA2723011A1 (en) 2009-11-05
EP2285411A1 (en) 2011-02-23
AR071420A1 (es) 2010-06-16
US20150105431A1 (en) 2015-04-16
CL2009001025A1 (es) 2010-09-24
BRPI0911847B8 (pt) 2021-05-25
DK2285411T3 (da) 2017-01-02
BRPI0911847B1 (pt) 2021-04-13
PT2285411T (pt) 2016-11-25
RU2010149050A (ru) 2012-06-10
EP2285411B1 (en) 2016-09-21
JP6159761B2 (ja) 2017-07-05
HK1153146A1 (zh) 2012-03-23
MX2010011929A (es) 2010-11-30
AU2009243065A1 (en) 2009-11-05
JP2011519862A (ja) 2011-07-14
BRPI0911847A8 (pt) 2018-03-06
CN102076362A (zh) 2011-05-25
CN102076362B (zh) 2015-01-21
JP2015232012A (ja) 2015-12-24
HUE031175T2 (en) 2017-06-28
MY164646A (en) 2018-01-30
PL2285411T3 (pl) 2017-07-31
US20130289079A1 (en) 2013-10-31
US8940772B2 (en) 2015-01-27
US8501164B2 (en) 2013-08-06

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Notification to applicant to reply to the report for non-patentability or inadequacy of the application [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/04/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME MEDIDA CAUTELAR DE 07/04/2021 - ADI 5.529/DF

B16C Correction of notification of the grant

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/04/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF