BRPI0911892A2 - polinucleotídeo, vetor, célula hospédeira, polipeptídeo e organismo não humano, transgênico, e uso dos mesmos, processo de geração de um polipeptídio com atividade de desaturase ou elongase, anticorpo e processo para a produção de uma composiçao de óleo, lipídio ou ácido graxo - Google Patents
polinucleotídeo, vetor, célula hospédeira, polipeptídeo e organismo não humano, transgênico, e uso dos mesmos, processo de geração de um polipeptídio com atividade de desaturase ou elongase, anticorpo e processo para a produção de uma composiçao de óleo, lipídio ou ácido graxoInfo
- Publication number
- BRPI0911892A2 BRPI0911892A2 BRPI0911892A BRPI0911892A BRPI0911892A2 BR PI0911892 A2 BRPI0911892 A2 BR PI0911892A2 BR PI0911892 A BRPI0911892 A BR PI0911892A BR PI0911892 A BRPI0911892 A BR PI0911892A BR PI0911892 A2 BRPI0911892 A2 BR PI0911892A2
- Authority
- BR
- Brazil
- Prior art keywords
- polypeptide
- desaturase
- polynucleotide
- lipid
- antibody
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title 2
- 102000004196 processed proteins & peptides Human genes 0.000 title 2
- 108090000765 processed proteins & peptides Proteins 0.000 title 2
- 235000014113 dietary fatty acids Nutrition 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 229930195729 fatty acid Natural products 0.000 title 1
- 239000000194 fatty acid Substances 0.000 title 1
- 150000004665 fatty acids Chemical class 0.000 title 1
- 150000002632 lipids Chemical class 0.000 title 1
- 102000040430 polynucleotide Human genes 0.000 title 1
- 108091033319 polynucleotide Proteins 0.000 title 1
- 239000002157 polynucleotide Substances 0.000 title 1
- 230000009261 transgenic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0083—Miscellaneous (1.14.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6432—Eicosapentaenoic acids [EPA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6434—Docosahexenoic acids [DHA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08155461 | 2008-04-30 | ||
| PCT/EP2009/055210 WO2009133145A1 (en) | 2008-04-30 | 2009-04-29 | Desaturase and method for the production of polyunsaturated fatty acids in transgenic organisms |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0911892A2 true BRPI0911892A2 (pt) | 2016-09-20 |
| BRPI0911892A8 BRPI0911892A8 (pt) | 2018-06-26 |
Family
ID=40809894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0911892A BRPI0911892A8 (pt) | 2008-04-30 | 2009-04-29 | polinucleotídeo, vetor, célula hospedeira, polipeptídeo e organismo não humano, transgênico, e uso dos mesmos, processo de geração de um polipeptídio com atividade de desaturase ou elongase, anticorpo e processo para a produção de uma composição de óleo, lipídio ou ácido graxo |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8785727B2 (pt) |
| EP (1) | EP2281051B1 (pt) |
| CN (1) | CN102066564B (pt) |
| AU (1) | AU2009242130B2 (pt) |
| BR (1) | BRPI0911892A8 (pt) |
| CA (1) | CA2723072C (pt) |
| ES (1) | ES2536796T3 (pt) |
| WO (1) | WO2009133145A1 (pt) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2166067B1 (de) | 2003-08-01 | 2015-07-01 | BASF Plant Science GmbH | Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen |
| US11952581B2 (en) | 2003-08-01 | 2024-04-09 | Basf Plant Science Gmbh | Process for the production of polyunsaturated fatty acids in transgenic organisms |
| MXPA06009572A (es) | 2004-02-27 | 2007-05-23 | Basf Plant Science Gmbh | Metodo para la produccion de acidos grasos poliinsaturados en plantas transgenicas. |
| AR059376A1 (es) * | 2006-02-21 | 2008-03-26 | Basf Plant Science Gmbh | Procedimiento para la produccion de acidos grasos poliinsaturados |
| WO2009130291A2 (de) | 2008-04-25 | 2009-10-29 | Basf Plant Science Gmbh | Pflanzensamenöl |
| CN113957054B (zh) | 2008-11-18 | 2024-07-16 | 联邦科学技术研究组织 | 产生ω-3脂肪酸的酶和方法 |
| CN102597242B (zh) | 2009-06-08 | 2016-03-02 | 罗特哈姆斯泰德研究有限公司 | 新脂肪酸延伸组合物及其用途 |
| EP2454278B1 (en) | 2009-07-17 | 2019-06-19 | BASF Plant Science Company GmbH | Novel fatty acid desaturases and elongases and uses thereof |
| US9388436B2 (en) | 2009-11-24 | 2016-07-12 | Basf Plant Science Company Gmbh | Fatty acid desaturase and uses thereof |
| WO2011064183A1 (en) | 2009-11-24 | 2011-06-03 | Basf Plant Science Company Gmbh | Novel fatty acid elongase and uses thereof |
| WO2012077020A1 (en) | 2010-12-06 | 2012-06-14 | Basf Plant Science Company Gmbh | Methods for production of synthetic promoters with defined specificity |
| ES2769448T3 (es) * | 2012-04-12 | 2020-06-25 | Rothamsted Res Limited | Producción de ácidos grasos poliinsaturados omega-3 de cadena larga |
| SG11201408362SA (en) | 2012-06-15 | 2015-01-29 | Commw Scient Ind Res Org | Production of long chain polyunsaturated fatty acids in plant cells |
| KR102386838B1 (ko) | 2013-12-18 | 2022-04-15 | 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 | 장쇄 다중불포화 지방산을 포함하는 지질 |
| CN103834672B (zh) * | 2014-03-17 | 2015-12-09 | 昆明理工大学 | 一种δ12-脂肪酸脱氢酶基因及其应用 |
| SG11201610596PA (en) | 2014-06-27 | 2017-01-27 | Commw Scient Ind Res Org | Lipid comprising docosapentaenoic acid |
| AU2015344980B2 (en) | 2014-11-14 | 2021-11-11 | Basf Plant Science Company Gmbh | Materials and methods for increasing the tocopherol content in seed oil |
| CN113249442B (zh) * | 2021-05-19 | 2023-03-14 | 中国科学院海洋研究所 | 一种筛查牡蛎不饱和脂肪酸含量相关甲基化修饰基因的方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2077896C (en) | 1990-03-16 | 2008-02-19 | Gregory A. Thompson | Plant desaturases - compositions and uses |
| PH31293A (en) | 1991-10-10 | 1998-07-06 | Rhone Poulenc Agrochimie | Production of y-linolenic acid by a delta6-desaturage. |
| US5614393A (en) * | 1991-10-10 | 1997-03-25 | Rhone-Poulenc Agrochimie | Production of γ-linolenic acid by a Δ6-desaturase |
| DK0616644T3 (da) | 1991-12-04 | 2003-10-27 | Du Pont | Fedtsyredesaturase-gener fra planter |
| CA2084348A1 (en) | 1991-12-31 | 1993-07-01 | David F. Hildebrand | Fatty acid alteration by a d9 desaturase in transgenic plant tissue |
| CA2149223C (en) | 1992-11-17 | 2007-04-24 | Jonathan Edward Lightner | Genes for microsomal delta-12 fatty acid desaturases and related enzymes from plants |
| US7205457B1 (en) | 1993-02-05 | 2007-04-17 | Monsanto Technology Llc | Altered linolenic and linoleic acid content in plants |
| FI962664A7 (fi) | 1993-12-28 | 1996-08-26 | Kirin Brewery | Rasvahappodesaturaasigeeni, tällaisen geenin sisältävä vektori, kasvi, joka sisältää siihen siirrettynä tällaisen geenin, ja menetelmä tälla isen kasvin aikaansaamiseksi |
| US6310194B1 (en) | 1994-09-26 | 2001-10-30 | Carnegie Institution Of Washington | Plant fatty acid hydroxylases |
| DE69635905T2 (de) | 1995-12-14 | 2006-12-21 | Cargill, Inc., Wayzata | Pflanzen mit mutierten Sequenzen, welche ein veränderten Fettsäuregehalt vermitteln |
| EP0794250A1 (en) | 1996-03-04 | 1997-09-10 | Soremartec S.A. | Isolation and sequencing of the hazel FAd2-N gene |
| DE69830587T2 (de) | 1997-04-11 | 2006-05-24 | Calgene Llc, Davis | Verfahren und zusammensetzungen für die synthese von langkettigen, mehrfach ungesättigten fettsäuren in pflanzen. |
| US5972664A (en) | 1997-04-11 | 1999-10-26 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
| US5968809A (en) | 1997-04-11 | 1999-10-19 | Abbot Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
| AR013633A1 (es) | 1997-04-11 | 2001-01-10 | Calgene Llc | METODO PARA LA ALTERACIoN DE LA COMPOSICIoN DE ÁCIDOS GRASOS DE CADENA MEDIA EN SEMILLAS VEGETALES QUE EXPRESAN UNA TIOESTERASA QUE PREFIERE CADENA MEDIA VEGETAL HETERoLOGA. |
| GB9724783D0 (en) | 1997-11-24 | 1998-01-21 | Inst Arable Crops Research | Novel polypeptides |
| WO1999064616A2 (en) | 1998-06-12 | 1999-12-16 | Abbott Laboratories | Polyunsaturated fatty acids in plants |
| JP2002527051A (ja) | 1998-10-09 | 2002-08-27 | メルク エンド カムパニー インコーポレーテッド | デルタ6脂肪酸デサチュラーゼ |
| JP4347572B2 (ja) | 2001-01-25 | 2009-10-21 | アボット・ラボラトリーズ | デサチュラーゼ遺伝子とその使用 |
| BR122019013214B1 (pt) | 2004-04-22 | 2022-04-12 | Commonwealth Scientific And Industrial Research Organisation | Polinucleotídeo isolado, vetor, célula recombinante, método para produzir uma célula recombinante, método para produzir um ou mais ácido graxo(s) poliinsaturado de cadeia longa, método para produzir uma semente transgênica, método para produzir óleo, método para produzir uma semente oleaginosa, extrato da semente transgênica, composição compreendendo o referido extrato, ração e uso da referida célula recombinante ou extrato |
| US7192762B2 (en) * | 2004-11-04 | 2007-03-20 | E. I. Du Pont De Nemours And Company | Mortierella alpina glycerol-3-phosphate o-acyltransferase for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms |
| GB0603160D0 (en) * | 2006-02-16 | 2006-03-29 | Rothamsted Res Ltd | Nucleic acid |
-
2009
- 2009-04-29 CN CN200980119681.0A patent/CN102066564B/zh not_active Expired - Fee Related
- 2009-04-29 BR BRPI0911892A patent/BRPI0911892A8/pt not_active Application Discontinuation
- 2009-04-29 CA CA2723072A patent/CA2723072C/en not_active Expired - Fee Related
- 2009-04-29 WO PCT/EP2009/055210 patent/WO2009133145A1/en not_active Ceased
- 2009-04-29 US US12/990,492 patent/US8785727B2/en not_active Expired - Fee Related
- 2009-04-29 EP EP09738189.1A patent/EP2281051B1/en not_active Not-in-force
- 2009-04-29 ES ES09738189.1T patent/ES2536796T3/es active Active
- 2009-04-29 AU AU2009242130A patent/AU2009242130B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009133145A1 (en) | 2009-11-05 |
| CN102066564B (zh) | 2015-02-11 |
| US8785727B2 (en) | 2014-07-22 |
| AU2009242130B2 (en) | 2013-09-19 |
| EP2281051B1 (en) | 2015-03-11 |
| CA2723072A1 (en) | 2009-11-05 |
| CA2723072C (en) | 2017-01-10 |
| AU2009242130A1 (en) | 2009-11-05 |
| ES2536796T3 (es) | 2015-05-28 |
| EP2281051A1 (en) | 2011-02-09 |
| CN102066564A (zh) | 2011-05-18 |
| BRPI0911892A8 (pt) | 2018-06-26 |
| US20110138490A1 (en) | 2011-06-09 |
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Legal Events
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| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
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| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |
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