BRPI0912136A2 - métodos para diagnosticar proliferação peroxissomal aumentada e para identificar uma substância para tratar proliferação peroxissomal aumentada, e, uso de pelo menos cinco analitos e de meios para a determinação de pelo menos cinco analitos - Google Patents

métodos para diagnosticar proliferação peroxissomal aumentada e para identificar uma substância para tratar proliferação peroxissomal aumentada, e, uso de pelo menos cinco analitos e de meios para a determinação de pelo menos cinco analitos

Info

Publication number
BRPI0912136A2
BRPI0912136A2 BRPI0912136A BRPI0912136A BRPI0912136A2 BR PI0912136 A2 BRPI0912136 A2 BR PI0912136A2 BR PI0912136 A BRPI0912136 A BR PI0912136A BR PI0912136 A BRPI0912136 A BR PI0912136A BR PI0912136 A2 BRPI0912136 A2 BR PI0912136A2
Authority
BR
Brazil
Prior art keywords
peroxismal
analytes
proliferation
increased
identifying
Prior art date
Application number
BRPI0912136A
Other languages
English (en)
Inventor
Alexandre Prokoudine
Bennard Van Ravenzwaay
Edgar Leibold
Eric Fabian
Georgia Coelho Palermo Cunha
Hennicke Kamp
Jan C Wiemer
Michael Manfred Herold
Ralf Looser
Tilmann B Walk
Volker Strauss
Werner Mellert
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of BRPI0912136A2 publication Critical patent/BRPI0912136A2/pt

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806—Determination of free amino acids
    • G01N33/6812—Assays for specific amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/046—Thyroid disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/200833—Carbonyl, ether, aldehyde or ketone containing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BRPI0912136A 2008-05-28 2009-05-26 métodos para diagnosticar proliferação peroxissomal aumentada e para identificar uma substância para tratar proliferação peroxissomal aumentada, e, uso de pelo menos cinco analitos e de meios para a determinação de pelo menos cinco analitos BRPI0912136A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08157118 2008-05-28
EP09151549 2009-01-28
PCT/EP2009/056386 WO2009153139A2 (en) 2008-05-28 2009-05-26 Means and methods for assessing increased peroxisomal proliferation

Publications (1)

Publication Number Publication Date
BRPI0912136A2 true BRPI0912136A2 (pt) 2015-11-03

Family

ID=41213166

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0912136A BRPI0912136A2 (pt) 2008-05-28 2009-05-26 métodos para diagnosticar proliferação peroxissomal aumentada e para identificar uma substância para tratar proliferação peroxissomal aumentada, e, uso de pelo menos cinco analitos e de meios para a determinação de pelo menos cinco analitos

Country Status (9)

Country Link
US (3) US8658427B2 (pt)
EP (1) EP2286245A2 (pt)
JP (1) JP5584680B2 (pt)
CN (1) CN102105797A (pt)
AU (1) AU2009259543B2 (pt)
BR (1) BRPI0912136A2 (pt)
CA (1) CA2724422A1 (pt)
DE (1) DE112009001301T5 (pt)
WO (1) WO2009153139A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2724422A1 (en) * 2008-05-28 2009-12-23 Basf Se Means and methods for assessing increased peroxisomal proliferation
CN102667789A (zh) * 2009-10-02 2012-09-12 梅塔博隆有限公司 用于分析复杂混合物中小分子成分的设备和相关方法
EP2529235B1 (en) 2010-01-29 2019-03-06 Metanomics GmbH Means and methods for diagnosing heart failure in a subject
JP2014526696A (ja) * 2011-09-14 2014-10-06 ビーエーエスエフ ソシエタス・ヨーロピア 生殖腺毒性を評価するための手段及び方法
CN106018783A (zh) * 2011-09-14 2016-10-12 巴斯夫欧洲公司 用于评估肾毒性的手段和方法
EP2815236A4 (en) * 2012-02-15 2015-11-04 Basf Se MEANS AND METHODS FOR ASSESSING ENDOCRINE DISEASE OR ENDOCRINE DISORDER
JP2015509603A (ja) * 2012-03-09 2015-03-30 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 肝疾患を評価するための手段および方法
US20150044702A1 (en) * 2012-03-09 2015-02-12 Basf Se Means and methods for assessing disorders related to impaired iron adsorption or energy metabolism
CN112798771B (zh) * 2021-03-31 2021-07-30 宝枫生物科技（北京）有限公司 用于诊断脑白质病变的生物标志物及其应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4540884A (en) * 1982-12-29 1985-09-10 Finnigan Corporation Method of mass analyzing a sample by use of a quadrupole ion trap
US5397894A (en) 1993-05-28 1995-03-14 Varian Associates, Inc. Method of high mass resolution scanning of an ion trap mass spectrometer
WO2000029846A2 (en) * 1998-11-13 2000-05-25 Curagen Corporation COMPOSITIONS AND METHODS RELATING TO THE PEROXISOMAL PROLIFERATOR ACTIVATED RECEPTOR-α MEDIATED PATHWAY
US6372431B1 (en) * 1999-11-19 2002-04-16 Incyte Genomics, Inc. Mammalian toxicological response markers
WO2003005628A2 (en) * 2001-07-06 2003-01-16 Lipomics Technologies, Inc. Generating, viewing, interpreting, and utilizing a quantitative database of metabolites
ATE443264T1 (de) * 2001-09-24 2009-10-15 Lipomics Technologies Inc Verfahren zur verwendung von quantitativen lipidmetabolondaten
WO2005026727A1 (en) * 2003-09-15 2005-03-24 Pfizer Products Inc. Methods for measuring peroxisome proliferation and peroxisomal induction
BRPI0613942B1 (pt) 2005-07-25 2022-04-05 Basf Aktiengesellschaft Métodos para a identificação de um composto que efetua o metaboloma de um roedor, e, para a identificação de um marcador para um composto que efetua o metaboloma de um roedor
AU2006274029B2 (en) * 2005-07-25 2011-07-14 Metanomics Gmbh Means and methods for analyzing a sample by means of chromatography-mass spectrometry
US20070037193A1 (en) * 2005-08-12 2007-02-15 Rong-Hwa Lin Modulation of peroxisome proliferator-activated receptors
US20070265216A1 (en) * 2005-10-05 2007-11-15 Gross Richard W Enhanced medical treatment in diabetic cardiomyopathy
EP2369346B1 (en) 2006-03-24 2014-08-27 Metanomics GmbH Method for diagnosing diabetes type II
US20080176266A1 (en) * 2006-08-17 2008-07-24 Alvin Berger Biomarkers Of Metabolic Responses To Hepatotoxicants And Carcinogens
CA2724422A1 (en) * 2008-05-28 2009-12-23 Basf Se Means and methods for assessing increased peroxisomal proliferation

Also Published As

Publication number Publication date
EP2286245A2 (en) 2011-02-23
CN102105797A (zh) 2011-06-22
JP5584680B2 (ja) 2014-09-03
JP2011523708A (ja) 2011-08-18
US20160169863A1 (en) 2016-06-16
US9304136B2 (en) 2016-04-05
US8658427B2 (en) 2014-02-25
US20110129933A1 (en) 2011-06-02
AU2009259543A1 (en) 2009-12-23
WO2009153139A2 (en) 2009-12-23
AU2009259543B2 (en) 2015-09-03
CA2724422A1 (en) 2009-12-23
WO2009153139A3 (en) 2010-02-18
US20140186964A1 (en) 2014-07-03
DE112009001301T5 (de) 2011-06-09

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