BRPI0912326A2 - análogos de acetaminofeno hidrossolúveis - Google Patents

análogos de acetaminofeno hidrossolúveis

Info

Publication number: BRPI0912326A2
Authority: BR; Brazil
Prior art keywords: water soluble; acetaminophen analogs; analogs; soluble acetaminophen; water
Prior art date: 2008-05-20

Application number

BRPI0912326A

Other languages

English (en)

Inventor

Keith R Bley

Naweed Muhammad

Original Assignee

Neurogesx Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-05-20

Filing date

2009-05-20

Publication date

2015-10-06

2009-05-20 Application filed by Neurogesx Inc filed Critical Neurogesx Inc

2015-10-06 Publication of BRPI0912326A2 publication Critical patent/BRPI0912326A2/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/094—Esters of phosphoric acids with arylalkanols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Dermatology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

BRPI0912326A 2008-05-20 2009-05-20 análogos de acetaminofeno hidrossolúveis BRPI0912326A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US5477408P	2008-05-20	2008-05-20
PCT/US2009/044743 WO2009143295A1 (en)	2008-05-20	2009-05-20	Water-soluble acetaminophen analogs

Publications (1)

Publication Number	Publication Date
BRPI0912326A2 true BRPI0912326A2 (pt)	2015-10-06

Family

ID=41340538

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0912326A BRPI0912326A2 (pt)	2008-05-20	2009-05-20	análogos de acetaminofeno hidrossolúveis

Country Status (12)

Country	Link
US (4)	US20110212926A1 (pt)
EP (1)	EP2291348A4 (pt)
JP (6)	JP5757864B2 (pt)
KR (1)	KR101698028B1 (pt)
CN (2)	CN105254662A (pt)
AU (1)	AU2009249067A1 (pt)
BR (1)	BRPI0912326A2 (pt)
CA (1)	CA2724877C (pt)
IL (1)	IL209382A0 (pt)
MX (1)	MX2010012648A (pt)
RU (1)	RU2010151952A (pt)
WO (1)	WO2009143295A1 (pt)

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EP2285419A4 (en)	2008-05-20	2012-05-02	Neurogesx Inc	LUBRICANT MUTUAL PARACETAMOL PRODRUGS
KR101677126B1 (ko)	2008-05-20	2016-11-22	노이로제스엑스, 인코포레이티드	탄산염 프로드러그 및 그것의 사용 방법
CA2724877C (en)	2008-05-20	2016-09-13	Neurogesx, Inc.	Water-soluble acetaminophen analogs
EP2177215A1 (en)	2008-10-17	2010-04-21	Laboratorios Del. Dr. Esteve, S.A.	Co-crystals of tramadol and NSAIDs
JP2014514300A (ja) *	2011-04-08	2014-06-19	スファエラファーマピーティーイーリミテッド	置換メチルホルミル試薬並びに化合物の物理化学的性質及び／又は薬物動態学的性質を改質するためのそれらの使用方法
JP6029670B2 (ja)	2011-09-22	2016-11-24	アコーダセラピューティクス、インク．	アセトアミノフェンコンジュゲートおよびその組成物ならびにその使用方法
CA3042642A1 (en)	2013-08-12	2015-02-19	Pharmaceutical Manufacturing Research Services, Inc.	Extruded immediate release abuse deterrent pill
US9492444B2 (en)	2013-12-17	2016-11-15	Pharmaceutical Manufacturing Research Services, Inc.	Extruded extended release abuse deterrent pill
US10172797B2 (en)	2013-12-17	2019-01-08	Pharmaceutical Manufacturing Research Services, Inc.	Extruded extended release abuse deterrent pill
AU2015290098B2 (en)	2014-07-17	2018-11-01	Pharmaceutical Manufacturing Research Services, Inc.	Immediate release abuse deterrent liquid fill dosage form
EP4578865A3 (en)	2014-08-12	2025-07-30	Monash University	Lymph directing prodrugs
US20160106737A1 (en)	2014-10-20	2016-04-21	Pharmaceutical Manufacturing Research Services, Inc.	Extended Release Abuse Deterrent Liquid Fill Dosage Form
RU2021103000A (ru)	2014-10-21	2021-03-01	Эббви Инк.	Пролекарства карбидопа и l-dopa и их применение для лечения болезни паркинсона
WO2016141065A1 (en) *	2015-03-03	2016-09-09	Kindred Biosciences, Inc.	Compositions and methods for treatment and prevention of pyrexia in horses
JP7118888B2 (ja)	2015-09-08	2022-08-16	モナッシュユニバーシティ	リンパ指向性プロドラッグ
JP2019515908A (ja) *	2016-04-20	2019-06-13	アッヴィ・インコーポレイテッド	カルビドパ及びｌ−ドパプロドラッグ並びに使用方法
EP3675838A4 (en)	2017-08-29	2021-04-21	PureTech LYT, Inc.	LIPID PRODRUGS DIRECTED TO THE LYMPHATIC SYSTEM
US11883497B2 (en)	2017-08-29	2024-01-30	Puretech Lyt, Inc.	Lymphatic system-directing lipid prodrugs
WO2019126378A1 (en)	2017-12-19	2019-06-27	Ariya Therapeutics, Inc.	Lipid prodrugs of mycophenolic acid and uses thereof
US11608345B1 (en)	2017-12-19	2023-03-21	Puretech Lyt, Inc.	Lipid prodrugs of rapamycin and its analogs and uses thereof
US11304954B2 (en)	2017-12-19	2022-04-19	Puretech Lyt, Inc.	Lipid prodrugs of mycophenolic acid and uses thereof
WO2020051585A1 (en)	2018-09-07	2020-03-12	R.P. Scherer Technologies, Llc	Solid or semisolid lipid based dosage form stabilization through curing and addition of low hlb surfactant(s)
EP3880210A1 (en)	2018-11-15	2021-09-22	Abbvie Inc.	Pharmaceutical formulations for subcutaneous administration
US11389409B2 (en) *	2019-08-30	2022-07-19	Remedy Diagnostics LLC	Transdermal device comprising acetaminophen prodrug
CA3166908A1 (en)	2020-02-05	2021-08-12	Daniel Kenneth BONNER	Lipid prodrugs of neurosteroids

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CA2671737A1 (en)	2006-12-05	2008-06-12	Neurogesx, Inc.	Prodrugs and methods of making and using the same
CA2724877C (en)	2008-05-20	2016-09-13	Neurogesx, Inc.	Water-soluble acetaminophen analogs
EP2285419A4 (en)	2008-05-20	2012-05-02	Neurogesx Inc	LUBRICANT MUTUAL PARACETAMOL PRODRUGS
KR101677126B1 (ko)	2008-05-20	2016-11-22	노이로제스엑스, 인코포레이티드	탄산염 프로드러그 및 그것의 사용 방법
US8569466B2 (en)	2008-09-10	2013-10-29	Nnochiri Ekwuribe	Aromatic carboxylic acid derivatives for treatment and prophylaxis of gastrointestinal diseases including colon cancers
US8575217B2 (en)	2009-03-16	2013-11-05	Genmedica Therapeutics Sl	Anti-inflammatory and antioxidant conjugates useful for treating metabolic disorders
JP6029670B2 (ja)	2011-09-22	2016-11-24	アコーダセラピューティクス、インク．	アセトアミノフェンコンジュゲートおよびその組成物ならびにその使用方法

2009
- 2009-05-20 CA CA2724877A patent/CA2724877C/en not_active Expired - Fee Related
- 2009-05-20 AU AU2009249067A patent/AU2009249067A1/en not_active Abandoned
- 2009-05-20 CN CN201510381430.7A patent/CN105254662A/zh active Pending
- 2009-05-20 CN CN2009801282182A patent/CN102149672A/zh active Pending
- 2009-05-20 WO PCT/US2009/044743 patent/WO2009143295A1/en not_active Ceased
- 2009-05-20 RU RU2010151952/04A patent/RU2010151952A/ru not_active Application Discontinuation
- 2009-05-20 KR KR1020107027998A patent/KR101698028B1/ko not_active Expired - Fee Related
- 2009-05-20 BR BRPI0912326A patent/BRPI0912326A2/pt not_active IP Right Cessation
- 2009-05-20 JP JP2011510691A patent/JP5757864B2/ja not_active Expired - Fee Related
- 2009-05-20 MX MX2010012648A patent/MX2010012648A/es active IP Right Grant
- 2009-05-20 EP EP09751523.3A patent/EP2291348A4/en not_active Withdrawn
- 2009-05-20 US US12/993,088 patent/US20110212926A1/en not_active Abandoned
2010
- 2010-11-17 IL IL209382A patent/IL209382A0/en unknown
2014
- 2014-03-13 JP JP2014049672A patent/JP2014111658A/ja not_active Withdrawn
2016
- 2016-02-01 JP JP2016016971A patent/JP6063072B2/ja not_active Expired - Fee Related
- 2016-03-22 US US15/077,802 patent/US9981998B2/en not_active Expired - Fee Related
- 2016-12-15 JP JP2016242968A patent/JP2017057217A/ja not_active Withdrawn
2018
- 2018-04-25 US US15/962,934 patent/US10442826B2/en not_active Expired - Fee Related
- 2018-05-23 JP JP2018098716A patent/JP2018135392A/ja not_active Withdrawn
2019
- 2019-09-09 US US16/565,173 patent/US11021498B2/en not_active Expired - Fee Related
2020
- 2020-04-20 JP JP2020074690A patent/JP2020114876A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
KR101698028B1 (ko)	2017-01-26
RU2010151952A (ru)	2012-06-27
CA2724877C (en)	2016-09-13
US20110212926A1 (en)	2011-09-01
EP2291348A4 (en)	2013-05-15
JP2018135392A (ja)	2018-08-30
US20160264605A1 (en)	2016-09-15
CN102149672A (zh)	2011-08-10
JP2011520977A (ja)	2011-07-21
JP2016084359A (ja)	2016-05-19
EP2291348A1 (en)	2011-03-09
KR20110018897A (ko)	2011-02-24
AU2009249067A1 (en)	2009-11-26
US11021498B2 (en)	2021-06-01
JP6063072B2 (ja)	2017-01-18
US9981998B2 (en)	2018-05-29
MX2010012648A (es)	2010-12-14
US20200002364A1 (en)	2020-01-02
WO2009143295A1 (en)	2009-11-26
JP2014111658A (ja)	2014-06-19
IL209382A0 (en)	2011-01-31
US20190092795A1 (en)	2019-03-28
CN105254662A (zh)	2016-01-20
JP2017057217A (ja)	2017-03-23
JP2020114876A (ja)	2020-07-30
CA2724877A1 (en)	2009-11-26
JP5757864B2 (ja)	2015-08-05
US10442826B2 (en)	2019-10-15

Legal Events

Date	Code	Title	Description
2015-12-08	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 5A E 6A ANUIDADES.
2016-04-05	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

Publication	Publication Date	Title
BRPI0912326A2 (pt)	2015-10-06	análogos de acetaminofeno hidrossolúveis
BRPI0911269A2 (pt)	2015-09-29	análogos de halicondrina b
BRPI0922508A2 (pt)	2015-08-11	Análogos de nucleosídeo
BRPI0823379A2 (pt)	2015-07-14	Análogos de glucagon
BRPI0823377A2 (pt)	2016-09-27	análogos de glucagon
BRPI0823378A2 (pt)	2019-09-24	análogos de glucagon
BRPI0823376A2 (pt)	2015-06-16	Análagos de glucagon
PT2260053E (pt)	2014-08-29	Análogos de oxitocina
EP2334253A4 (en)	2015-06-24	WATER SEPARATOR
BRPI0920833A2 (pt)	2015-12-22	preparação de benzonorborbenos
BRPI0912333A2 (pt)	2015-10-06	reservatório de água
BRPI0920819A2 (pt)	2015-12-22	raspador
BRPI0920777A2 (pt)	2016-03-08	análogos de somatostatina
FR2926061B1 (fr)	2009-12-18	Structure aquatique insubmersible
ITVA20080014U1 (it)	2008-07-30	Snodo per scopino water
TH96956B (th)	2009-07-24	ถ้วยน้ำ
UA17269S (uk)	2008-09-10	Посудина на воду
UA17086S (uk)	2008-08-11	Посудина на воду
FI8319U1 (fi)	2009-06-16	Kaavin
FI20086184A7 (fi)	2010-06-11	Kaavari
CN300939416S (zh)	2009-06-10	净水机(mf119-3)
UA16114S (uk)	2008-03-25	Посудина на воду
TH101801B (th)	2010-06-25	แก้วน้ำ
TH101785B (th)	2010-06-25	แก้วน้ำ
TH101798B (th)	2010-06-25	แก้วน้ำ