BRPI0912546A2 - síntese de di-hidrotieno[3,2-d]-pirimidino dióis e pirimidino dióis similares. - Google Patents

síntese de di-hidrotieno[3,2-d]-pirimidino dióis e pirimidino dióis similares.

Info

Publication number: BRPI0912546A2
Authority: BR; Brazil
Prior art keywords: pyrimidine diols; dihydrothieno; synthesis; diols; similar
Prior art date: 2008-05-13

Application number

BRPI0912546A

Other languages

English (en)

Inventor

Chris Hugh Senanayake

Dhileepkumar Krishnamurthy

Jason Alan Mulder

Rogelio Perez Frutos

Thomas G Tampone

Original Assignee

Boehringer Ingelheim Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-05-13

Filing date

2009-05-07

Publication date

2016-10-18

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41319263&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0912546(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-05-07 Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int

2016-10-18 Publication of BRPI0912546A2 publication Critical patent/BRPI0912546A2/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

BRPI0912546A 2008-05-13 2009-05-07 síntese de di-hidrotieno[3,2-d]-pirimidino dióis e pirimidino dióis similares. BRPI0912546A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US5281608P	2008-05-13	2008-05-13
PCT/US2009/043068 WO2009140127A2 (en)	2008-05-13	2009-05-07	SYNTHESIS OF DIHYDROTHIENO[3,2-d]PYRIMIDINE DIOLS AND SIMILAR PYRIMIDINE DIOLS

Publications (1)

Publication Number	Publication Date
BRPI0912546A2 true BRPI0912546A2 (pt)	2016-10-18

Family

ID=41319263

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0912546A BRPI0912546A2 (pt)	2008-05-13	2009-05-07	síntese de di-hidrotieno[3,2-d]-pirimidino dióis e pirimidino dióis similares.

Country Status (31)

Country	Link
US (1)	US8471010B2 (pt)
EP (1)	EP2315755B1 (pt)
JP (1)	JP5281153B2 (pt)
KR (1)	KR20110021764A (pt)
CN (1)	CN102026984B (pt)
AR (1)	AR071720A1 (pt)
AU (1)	AU2009246686B2 (pt)
BR (1)	BRPI0912546A2 (pt)
CA (1)	CA2722970A1 (pt)
CL (1)	CL2009001149A1 (pt)
CO (1)	CO6260135A2 (pt)
CY (1)	CY1113577T1 (pt)
DK (1)	DK2315755T3 (pt)
EA (1)	EA019735B1 (pt)
EC (1)	ECSP10010571A (pt)
ES (1)	ES2392920T3 (pt)
HR (1)	HRP20120860T1 (pt)
IL (1)	IL208382A0 (pt)
MA (1)	MA32312B1 (pt)
ME (1)	ME01465B (pt)
MX (1)	MX2010011025A (pt)
MY (1)	MY152292A (pt)
NZ (1)	NZ588484A (pt)
PL (1)	PL2315755T3 (pt)
PT (1)	PT2315755E (pt)
RS (1)	RS52476B (pt)
SI (1)	SI2315755T1 (pt)
TW (1)	TWI421254B (pt)
UA (1)	UA99964C2 (pt)
WO (1)	WO2009140127A2 (pt)
ZA (1)	ZA201006891B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SA08280783B1 (ar) *	2007-01-11	2011-04-24	استرازينيكا ايه بي	مشتقات بيريدوبيريميدين كمثبطات pde4
US9173884B2 (en)	2011-11-30	2015-11-03	Trustees Of Boston College	Inhibitors of phosphodiesterase 11 (PDE11)
CN117820328A (zh) *	2023-11-21	2024-04-05	苏州楚凯药业有限公司	一种2,4-二氯-6,7-二氢呋喃并[3,2-d]嘧啶的合成方法
WO2025131986A1 (en)	2023-12-19	2025-06-26	Boehringer Ingelheim International Gmbh	Novel synthetic steps for the manufacturing method of the pde4b-inhibitor 1-({(5r)-2-[4-(5-chloropyrimidine-2-yl)piperidine-1-yl]-5-oxido-6,7-dihydrothieno[3,2-d]pyrimidine-4-yl}amino)cyclobutyl]methanol

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1470336A1 (de) *	1962-07-04	1969-03-20	Thomae Gmbh Dr K	Neue Dihydrothieno-[3,4-d]-pyrimidine und Verfahren zu ihrer Herstellung
FR2029250A5 (pt)	1969-01-21	1970-10-16	Roussel Uclaf
AR044743A1 (es)	2002-09-26	2005-10-05	Nihon Nohyaku Co Ltd	Herbicida, metodo de emplearlo, derivados de tienopirimidina sustituida,compuestos intermediarios, y procedimientos que se utilizan para producirlos,
CN101163706A (zh) *	2005-04-21	2008-04-16	贝林格尔·英格海姆国际有限公司	用于治疗炎性疾病的二氢噻吩并嘧啶
US7851468B2 (en) *	2006-05-15	2010-12-14	Cephalon, Inc.	Substituted pyrazolo[3,4-d]pyrimidines

2009
- 2009-05-07 SI SI200930337T patent/SI2315755T1/sl unknown
- 2009-05-07 MY MYPI20105081 patent/MY152292A/en unknown
- 2009-05-07 BR BRPI0912546A patent/BRPI0912546A2/pt not_active IP Right Cessation
- 2009-05-07 HR HRP20120860AT patent/HRP20120860T1/hr unknown
- 2009-05-07 KR KR1020107025268A patent/KR20110021764A/ko not_active Withdrawn
- 2009-05-07 ES ES09736709T patent/ES2392920T3/es active Active
- 2009-05-07 WO PCT/US2009/043068 patent/WO2009140127A2/en not_active Ceased
- 2009-05-07 DK DK09736709.8T patent/DK2315755T3/da active
- 2009-05-07 NZ NZ588484A patent/NZ588484A/en not_active IP Right Cessation
- 2009-05-07 RS RS20120445A patent/RS52476B/sr unknown
- 2009-05-07 US US12/989,575 patent/US8471010B2/en active Active
- 2009-05-07 AU AU2009246686A patent/AU2009246686B2/en not_active Ceased
- 2009-05-07 CN CN2009801169809A patent/CN102026984B/zh not_active Expired - Fee Related
- 2009-05-07 PL PL09736709T patent/PL2315755T3/pl unknown
- 2009-05-07 CA CA2722970A patent/CA2722970A1/en not_active Abandoned
- 2009-05-07 PT PT09736709T patent/PT2315755E/pt unknown
- 2009-05-07 EA EA201001775A patent/EA019735B1/ru not_active IP Right Cessation
- 2009-05-07 JP JP2011509563A patent/JP5281153B2/ja active Active
- 2009-05-07 ME MEP-2012-113A patent/ME01465B/me unknown
- 2009-05-07 MX MX2010011025A patent/MX2010011025A/es active IP Right Grant
- 2009-05-07 EP EP09736709A patent/EP2315755B1/en active Active
- 2009-05-12 AR ARP090101712A patent/AR071720A1/es unknown
- 2009-05-12 CL CL2009001149A patent/CL2009001149A1/es unknown
- 2009-05-12 TW TW098115740A patent/TWI421254B/zh not_active IP Right Cessation
- 2009-07-05 UA UAA201014583A patent/UA99964C2/ru unknown
2010
- 2010-09-28 ZA ZA2010/06891A patent/ZA201006891B/en unknown
- 2010-10-03 IL IL208382A patent/IL208382A0/en unknown
- 2010-10-26 EC EC2010010571A patent/ECSP10010571A/es unknown
- 2010-11-10 CO CO10140646A patent/CO6260135A2/es active IP Right Grant
- 2010-11-12 MA MA33361A patent/MA32312B1/fr unknown
2012
- 2012-10-31 CY CY20121101046T patent/CY1113577T1/el unknown

Also Published As

Publication number	Publication date
CN102026984A (zh)	2011-04-20
CL2009001149A1 (es)	2010-07-23
AR071720A1 (es)	2010-07-07
MX2010011025A (es)	2010-11-05
AU2009246686B2 (en)	2014-02-13
JP5281153B2 (ja)	2013-09-04
EA201001775A1 (ru)	2011-06-30
US20110130563A1 (en)	2011-06-02
EP2315755B1 (en)	2012-08-08
KR20110021764A (ko)	2011-03-04
TWI421254B (zh)	2014-01-01
ZA201006891B (en)	2011-06-29
ES2392920T3 (es)	2012-12-17
WO2009140127A3 (en)	2010-01-28
MY152292A (en)	2014-09-15
UA99964C2 (en)	2012-10-25
ME01465B (me)	2014-04-20
RS52476B (sr)	2013-02-28
US8471010B2 (en)	2013-06-25
EA019735B1 (ru)	2014-05-30
TW201006841A (en)	2010-02-16
EP2315755A2 (en)	2011-05-04
AU2009246686A1 (en)	2009-11-19
SI2315755T1 (sl)	2012-10-30
CA2722970A1 (en)	2009-11-19
IL208382A0 (en)	2010-12-30
HK1151524A1 (en)	2012-02-03
NZ588484A (en)	2012-06-29
WO2009140127A2 (en)	2009-11-19
PL2315755T3 (pl)	2013-01-31
CY1113577T1 (el)	2016-06-22
CN102026984B (zh)	2013-12-25
MA32312B1 (fr)	2011-05-02
CO6260135A2 (es)	2011-03-22
JP2011520886A (ja)	2011-07-21
HRP20120860T1 (hr)	2012-11-30
ECSP10010571A (es)	2010-11-30
PT2315755E (pt)	2012-10-03
DK2315755T3 (da)	2012-10-15

Legal Events

Date	Code	Title	Description
2016-10-25	B15I	Others concerning applications: loss of priority
2016-11-16	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 7A ANUIDADE.
2017-03-01	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
2021-06-08	B350	Update of information on the portal [chapter 15.35 patent gazette]

Publication	Publication Date	Title
BRPI0818671A2 (pt)	2015-09-15	preparação de diidrotieno[3,2-d]pirimidinas e intermediários empregados nela
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PT3037529T (pt)	2019-05-31	Polipéptidos ph20 estendidos solúveis e suas utilizações
BRPI0817853A2 (pt)	2014-10-14	Variantes de glucoamilase com propriedades alteradas
BRPI0907435A2 (pt)	2015-07-14	Derivados de 5-flúor pirimidina
BRPI0914544A2 (pt)	2015-12-15	derivados de pirimidona substituídos
BRPI0917558A2 (pt)	2015-11-17	detecção de células com cancelamento de interferência
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DK3196302T3 (da)	2020-09-14	Små enzymholdige granuler
FI20075892L (fi)	2009-09-07	Kommunikointi- ja kulunseurantajärjestely
BRPI0811115A2 (pt)	2014-12-23	Compostos de heteroarilamida pirimidona
FR2920307B1 (fr)	2010-06-04	Utilisation cosmetique de microorganismes.
IT1392538B1 (it)	2012-03-09	Catena di sfere e metodo per produrre la stessa.
BRPI0909422A2 (pt)	2015-12-01	conjunto de artigos.
BRPI1006058A2 (pt)	2015-09-01	"fermentação de carboidrato"
BRPI0811094A2 (pt)	2014-12-09	Derivados de heteroarilamida pirimidona
BRPI0811527A2 (pt)	2014-11-18	Derivados de arilamida pirimidona
FR2939766B1 (fr)	2011-01-14	Pylone central d'aeronef.
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BRPI0911622A2 (pt)	2015-10-13	derivados de benzoxepina e benzociclo-heptano.
FR2929850B1 (fr)	2012-08-17	Inhibiteurs de l'enzyme tyrosinage
BRPI0814627A2 (pt)	2015-01-27	Derivados de malonamida com atividade antitrombótica