BRPI0913058A2 - composições farmacêuticas de conjugados somatostatina/dopamina - Google Patents

composições farmacêuticas de conjugados somatostatina/dopamina

Info

Publication number: BRPI0913058A2
Authority: BR; Brazil
Prior art keywords: somatostatin; pharmaceutical compositions; dopamine conjugate; conjugate pharmaceutical; dopamine
Prior art date: 2008-05-14

Application number

BRPI0913058A

Other languages

English (en)

Inventor

Jundong Zhang

Zheng Xin Dong

Original Assignee

Ipsen Pharma Sas

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-05-14

Filing date

2009-05-12

Publication date

2015-10-13

2009-05-12 Application filed by Ipsen Pharma Sas filed Critical Ipsen Pharma Sas

2015-10-13 Publication of BRPI0913058A2 publication Critical patent/BRPI0913058A2/pt

Links

VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 title 2
102000005157 Somatostatin Human genes 0.000 title 1
108010056088 Somatostatin Proteins 0.000 title 1
229960003638 dopamine Drugs 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 title 1
229960000553 somatostatin Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Immunology (AREA)
Hematology (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Child & Adolescent Psychology (AREA)
Emergency Medicine (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Nutrition Science (AREA)
Ophthalmology & Optometry (AREA)
Vascular Medicine (AREA)
Addiction (AREA)
Psychiatry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

BRPI0913058A 2008-05-14 2009-05-12 composições farmacêuticas de conjugados somatostatina/dopamina BRPI0913058A2 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US12758408P	2008-05-14	2008-05-14
US20005808P	2008-11-24	2008-11-24
PCT/US2009/002943 WO2009139855A2 (en)	2008-05-14	2009-05-12	Pharmaceutical compositions of somatostatin-dopamine conjugates

Publications (1)

Publication Number	Publication Date
BRPI0913058A2 true BRPI0913058A2 (pt)	2015-10-13

Family

ID=41319209

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0913058A BRPI0913058A2 (pt)	2008-05-14	2009-05-12	composições farmacêuticas de conjugados somatostatina/dopamina

Country Status (11)

Country	Link
US (1)	US20110065632A1 (pt)
EP (1)	EP2296687A4 (pt)
JP (1)	JP5350467B2 (pt)
KR (1)	KR20110010115A (pt)
CN (1)	CN102088998A (pt)
AU (1)	AU2009246894A1 (pt)
BR (1)	BRPI0913058A2 (pt)
CA (1)	CA2724534A1 (pt)
MX (1)	MX2010012124A (pt)
RU (1)	RU2464039C2 (pt)
WO (1)	WO2009139855A2 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5486690B2 (ja) *	2009-11-16	2014-05-07	イプセンファルマソシエテパールアクシオンサンプリフィエ	メラノコルチン受容体リガンドの医薬組成物
CN102821775B (zh) *	2010-03-15	2014-10-22	益普生制药股份有限公司	生长激素促分泌素受体配体的药物组合物
TWI523863B (zh) *	2012-11-01	2016-03-01	艾普森藥品公司	體抑素－多巴胺嵌合體類似物
EP2914276A4 (en) *	2012-11-01	2016-07-13	Ipsen Pharma Sas	SOMATOSTATIN ANALOGA AND DIMERE OUT
CN109890423A (zh) *	2016-10-28	2019-06-14	塔弗达治疗有限公司	Sstr靶向缀合物及其颗粒和制剂
GB2590341A (en) *	2019-10-04	2021-06-23	Tiburio Therapeutics Inc	Storage stable somatostatin-dopamine chimeric compounds and salt forms thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4537893A (en) *	1984-04-27	1985-08-27	Eli Lilly And Company	Octahydrothiazolo[4,5-g]quinolines and use as prolactin secretion inhibitors
NZ214698A (en) *	1984-12-31	1988-08-30	Merrell Dow Pharma	Thiophene derivatives and pharmaceutical compositions containing such
JPH09510182A (ja) *	1993-11-17	1997-10-14	エルディーエス・テクノロジーズ・インコーポレーテッド	カプセル封入されたドラッグデリバリー用透明液
US6309663B1 (en) *	1999-08-17	2001-10-30	Lipocine Inc.	Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents
US20060034937A1 (en) *	1999-11-23	2006-02-16	Mahesh Patel	Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
BR0210915A (pt) *	2001-06-08	2004-06-08	Sod Conseils Rech Applic	Análogos quiméricos de somatostatina-dopamina
AU2002322403A1 (en) *	2001-08-23	2003-03-10	Eli Lilly And Company	Glucagon-like peptide-1 analogs
CN101653594A (zh) *	2003-04-11	2010-02-24	研究及应用科学协会股份有限公司	生长激素释放抑制因子-多巴胺嵌合类似物
US7329638B2 (en) *	2003-04-30	2008-02-12	The Regents Of The University Of Michigan	Drug delivery compositions
EP1694278A4 (en) *	2003-12-16	2009-08-12	Ipsen Pharma	GLP-1 PHARMACEUTICAL COMPOSITIONS
GB0412866D0 (en) *	2004-06-09	2004-07-14	Novartis Ag	Organic compounds
US7402652B2 (en) *	2004-09-14	2008-07-22	Miller Landon C G	Baclofen conjugate and a pharmaceutical composition for treatment of neuronal disorders
AU2006339072A1 (en) *	2005-03-14	2007-10-25	Board Of Regents Of The University Of Texas System	Bioactive FUS1 peptides and nanoparticle-polypeptide complexes
US20060292099A1 (en) *	2005-05-25	2006-12-28	Michael Milburn	Treatment of eye disorders with sirtuin modulators
WO2007127158A2 (en) *	2006-04-25	2007-11-08	Croda, Inc	Modification of percutaneous absorption of topically active materials

2009
- 2009-05-12 WO PCT/US2009/002943 patent/WO2009139855A2/en not_active Ceased
- 2009-05-12 AU AU2009246894A patent/AU2009246894A1/en not_active Abandoned
- 2009-05-12 CN CN2009801272547A patent/CN102088998A/zh active Pending
- 2009-05-12 EP EP09746943A patent/EP2296687A4/en not_active Withdrawn
- 2009-05-12 KR KR1020107028063A patent/KR20110010115A/ko not_active Ceased
- 2009-05-12 BR BRPI0913058A patent/BRPI0913058A2/pt not_active IP Right Cessation
- 2009-05-12 MX MX2010012124A patent/MX2010012124A/es active IP Right Grant
- 2009-05-12 RU RU2010150947/15A patent/RU2464039C2/ru not_active IP Right Cessation
- 2009-05-12 US US12/991,348 patent/US20110065632A1/en not_active Abandoned
- 2009-05-12 JP JP2011509477A patent/JP5350467B2/ja not_active Expired - Fee Related
- 2009-05-12 CA CA2724534A patent/CA2724534A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP2296687A2 (en)	2011-03-23
RU2464039C2 (ru)	2012-10-20
JP2011520879A (ja)	2011-07-21
KR20110010115A (ko)	2011-01-31
CA2724534A1 (en)	2009-11-19
MX2010012124A (es)	2011-04-05
US20110065632A1 (en)	2011-03-17
AU2009246894A1 (en)	2009-11-19
EP2296687A4 (en)	2012-12-26
RU2010150947A (ru)	2012-06-20
CN102088998A (zh)	2011-06-08
WO2009139855A3 (en)	2009-12-30
JP5350467B2 (ja)	2013-11-27
WO2009139855A2 (en)	2009-11-19

Legal Events

Date	Code	Title	Description
2015-12-08	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 5A E 6A ANUIDADES.
2016-04-05	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

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