BRPI0916395A2 - compostos de 1,6-di-hidro-2h-3-oxa-6-aza-as-indaceno - Google Patents

compostos de 1,6-di-hidro-2h-3-oxa-6-aza-as-indaceno

Info

Publication number: BRPI0916395A2
Authority: BR; Brazil
Prior art keywords: aza; oxa; dihydro; indacene compounds; indacene
Prior art date: 2008-07-30

Application number

BRPI0916395A

Other languages

English (en)

Inventor

Albert Palomer

Antonio Guglietta

José L Falcó

Original Assignee

Ferrer Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-07-30

Filing date

2009-07-29

Publication date

2016-02-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41138660&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0916395(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-07-29 Application filed by Ferrer Int filed Critical Ferrer Int

2016-02-16 Publication of BRPI0916395A2 publication Critical patent/BRPI0916395A2/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Psychiatry (AREA)
Obesity (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Psychology (AREA)
Anesthesiology (AREA)
Child & Adolescent Psychology (AREA)
Hospice & Palliative Care (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)

BRPI0916395A 2008-07-30 2009-07-29 compostos de 1,6-di-hidro-2h-3-oxa-6-aza-as-indaceno BRPI0916395A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP08161485		2008-07-30
PCT/EP2009/059829 WO2010012789A1 (en)	2008-07-30	2009-07-29	1,6-dihydro-2h-3-oxa-6-aza-as-indacene compounds

Publications (1)

Publication Number	Publication Date
BRPI0916395A2 true BRPI0916395A2 (pt)	2016-02-16

Family

ID=41138660

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0916395A BRPI0916395A2 (pt)	2008-07-30	2009-07-29	compostos de 1,6-di-hidro-2h-3-oxa-6-aza-as-indaceno

Country Status (16)

Country	Link
US (1)	US8227501B2 (pt)
EP (1)	EP2350088A1 (pt)
JP (1)	JP2011529477A (pt)
KR (1)	KR20110041495A (pt)
CN (1)	CN102112480A (pt)
AR (1)	AR075262A1 (pt)
AU (1)	AU2009275918A1 (pt)
BR (1)	BRPI0916395A2 (pt)
CA (1)	CA2731405A1 (pt)
CL (1)	CL2011000184A1 (pt)
MX (1)	MX2011001062A (pt)
PE (1)	PE20110208A1 (pt)
RU (1)	RU2011107443A (pt)
TW (1)	TW201018695A (pt)
UY (1)	UY32016A (pt)
WO (1)	WO2010012789A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN103601683B (zh) *	2010-04-16	2016-03-30	中国科学院上海药物研究所	苯并杂环类化合物及其制备方法和用途
AR091699A1 (es) *	2012-07-10	2015-02-25	Astellas Pharma Inc	Derivado de indol carboxamida
CN104109143B (zh) *	2013-04-22	2018-04-27	上海阳帆医药科技有限公司	一类褪黑激素(mt1-mt2)受体激动剂及其制备方法与用途
CN104326916B (zh) *	2014-10-10	2017-09-22	青岛农业大学	2‑氟‑4‑烯丙基‑6‑硝基苯酚与2‑氟‑4‑硝基‑6‑烯丙基苯酚的联合制备及用途
MY203941A (en) *	2016-06-17	2024-07-25	Daewoong Pharmaceutical Co Ltd	Method for producing diphenylmethane derivative
CA3244229A1 (en) *	2021-12-24	2023-06-29	Psylo Pty Ltd	COMPOUNDS
KR20240044190A (ko) *	2022-09-28	2024-04-04	주식회사 대웅제약	이나보글리플로진의 신규한 결정형 및 이의 제조방법

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4600723A (en)	1983-05-18	1986-07-15	Monash University	Method for minimizing disturbances in circadian rhythms of bodily performance and function
EP0126630B1 (en)	1983-05-18	1987-09-16	Monash University	The use of melatonin for the manufacture of a medicament
WO1989001472A1 (en)	1987-08-17	1989-02-23	Nelson Research & Development Co.	Melatonin analogues
FR2680366B1 (fr)	1991-08-13	1995-01-20	Adir	Nouveaux derives d'arylethylamines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
GB9326192D0 (en)	1993-12-22	1994-02-23	Glaxo Group Ltd	Chemical compounds
WO1997001539A1 (en)	1995-06-27	1997-01-16	Takeda Chemical Industries, Ltd.	4-acylamino(halogeno) alkyl-quinoline derivatives, their preparation and their use as melatonin agonists
US5732360A (en)	1995-09-08	1998-03-24	At & T Wireless Services And Atmel Corp	Mobile telecommunication device and method used for changing wireless communication between base stations of different kinds
US6034239A (en)	1996-03-08	2000-03-07	Takeda Chemical Industries, Ltd.	Tricyclic compounds, their production and use
WO1997032871A1 (en)	1996-03-08	1997-09-12	Takeda Chemical Industries, Ltd.	Tricyclic compounds, their production and use
FR2771739B1 (fr)	1997-11-28	2001-04-20	Adir	Nouveaux composes naphtaleniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2784375B1 (fr)	1998-10-12	2000-11-24	Adir	Nouveaux derives cycliques a chaine cycloalkylenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2793793B1 (fr)	1999-05-19	2004-02-27	Adir	Nouveaux derives dimeriques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU6595100A (en)	1999-08-20	2001-03-19	Takeda Chemical Industries Ltd.	Percutaneous absorption agents
FR2799757B1 (fr)	1999-10-15	2001-12-14	Adir	Nouveaux derives polycycliques azaindoliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6737431B2 (en)	2002-03-12	2004-05-18	Bristol-Myers Squibb Company	Benzoxazole derivatives as novel melatonergic agents
BR0312175A (pt)	2002-06-21	2005-04-05	Suven Life Sciences Ltd	Composto, composição farmacêutica, uso de um composto, método para o tratamento e método para reduzir a morbidez e a mortalidade associadas com o excesso de peso
US6908931B2 (en)	2003-04-10	2005-06-21	Bristol-Myers Squibb Company	Tetrahydroisoquinoline derivatives as melatonin MT2 antagonists
WO2005062992A2 (en)	2003-12-23	2005-07-14	Abraxis Bioscience, Inc	Substituted melatonin derivatives, process for their preparation, and methods of use

2009
- 2009-07-29 BR BRPI0916395A patent/BRPI0916395A2/pt not_active IP Right Cessation
- 2009-07-29 TW TW098125512A patent/TW201018695A/zh unknown
- 2009-07-29 US US13/056,492 patent/US8227501B2/en not_active Expired - Fee Related
- 2009-07-29 RU RU2011107443/04A patent/RU2011107443A/ru not_active Application Discontinuation
- 2009-07-29 PE PE2011000041A patent/PE20110208A1/es not_active Application Discontinuation
- 2009-07-29 JP JP2011520509A patent/JP2011529477A/ja not_active Abandoned
- 2009-07-29 KR KR1020117002324A patent/KR20110041495A/ko not_active Withdrawn
- 2009-07-29 WO PCT/EP2009/059829 patent/WO2010012789A1/en not_active Ceased
- 2009-07-29 CN CN2009801300227A patent/CN102112480A/zh active Pending
- 2009-07-29 AU AU2009275918A patent/AU2009275918A1/en not_active Abandoned
- 2009-07-29 AR ARP090102880A patent/AR075262A1/es unknown
- 2009-07-29 UY UY0001032016A patent/UY32016A/es unknown
- 2009-07-29 EP EP09781255A patent/EP2350088A1/en not_active Withdrawn
- 2009-07-29 MX MX2011001062A patent/MX2011001062A/es active IP Right Grant
- 2009-07-29 CA CA2731405A patent/CA2731405A1/en not_active Abandoned
2011
- 2011-01-28 CL CL2011000184A patent/CL2011000184A1/es unknown

Also Published As

Publication number	Publication date
JP2011529477A (ja)	2011-12-08
MX2011001062A (es)	2011-03-24
CL2011000184A1 (es)	2011-09-16
AR075262A1 (es)	2011-03-23
CA2731405A1 (en)	2010-02-04
WO2010012789A1 (en)	2010-02-04
US8227501B2 (en)	2012-07-24
AU2009275918A1 (en)	2010-02-04
EP2350088A1 (en)	2011-08-03
RU2011107443A (ru)	2012-09-10
KR20110041495A (ko)	2011-04-21
US20110144178A1 (en)	2011-06-16
CN102112480A (zh)	2011-06-29
PE20110208A1 (es)	2011-03-28
UY32016A (es)	2010-01-29
TW201018695A (en)	2010-05-16

Legal Events

Date	Code	Title	Description
2016-06-28	B08F	Application fees: application dismissed [chapter 8.6 patent gazette]	Free format text: REFERENTE A 4A,6A E 7A ANUIDADES
2016-10-18	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2373 DE 28-06-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

Publication	Publication Date	Title
BRPI0923786A2 (pt)	2016-07-26	compostos 5,6-dihidro-6-fenilbenzo(f) isoquinolina-2- amina substituidos
BRPI0815717A2 (pt)	2015-02-10	Compostos de imidazopirazina.
ATE555107T1 (de)	2012-05-15	2-aza-bicyclo-ä2,2,1-üheptan-derivate
NO2021006I1 (no)	2021-02-15	Quofenix, delafloksacin
BRPI0815042A2 (pt)	2015-02-10	Compostos de pirazol
BRPI0816970A2 (pt)	2015-03-24	1,3-dissubstituídas-4-fenil-1h-piridin-2-onas
BRPI0815067A2 (pt)	2015-02-10	Compostos de biciclotactama substituída
BRPI0811718A2 (pt)	2014-11-18	Derivados de 3,3-espiroindolinona
HRP20151058T1 (xx)	2015-12-04	Ariloazol-2-il-cijanoetilamino-spojevi, postupak njihove proizvodnje i postupak njihove uporabe
BRPI0910229A2 (pt)	2015-09-01	Tetramatos de 4';4'-dioxaspiro espirociclicamente substituídos
BRPI0922904A2 (pt)	2018-05-29	"compostos"
BRPI0907563A2 (pt)	2015-08-04	Derivados de 4,5-di-hidro-xazol-2-il amina
DK2205562T3 (da)	2011-06-14	1,1,1-trifluor-2-hydroxy-3-phenylpropanderivater
BRPI0918472A2 (pt)	2015-12-01	composto 2,4-diaminopirimidina
BRPI0813500A2 (pt)	2015-01-06	Compostos antivirais
BRPI0821086A2 (pt)	2014-10-07	Compostos inseticidas
EP2129224A4 (en)	2011-01-05	5,6-dihydro-1H-pyridin-2-one compounds
UY33125A (es)	2011-07-29	Diaza-espiro-[5,5]-undecanos
BRPI0811264A2 (pt)	2014-11-04	Compostos
EP2344471A4 (en)	2012-05-30	7-PIPERIDINALKYL-3,4-dihydroquinolone DERIVATIVE
BRPI0814424A2 (pt)	2015-01-06	Compostos heterociclila
BRPI0809996A2 (pt)	2014-10-14	Compostos
BRPI0907108A2 (pt)	2016-07-26	escova de dentes.
BRPI0815059A2 (pt)	2015-02-10	Derivado de 1,3-di-hidroisoindol
BRPI0917446A2 (pt)	2015-12-22	derivados de acilaminobenzamida.