BRPI0918726A2 - derivados de 1-amino-alquilciclohexano para o tratamento de deficiência cognitiva em tinido - Google Patents

derivados de 1-amino-alquilciclohexano para o tratamento de deficiência cognitiva em tinido

Info

Publication number
BRPI0918726A2
BRPI0918726A2 BRPI0918726A BRPI0918726A BRPI0918726A2 BR PI0918726 A2 BRPI0918726 A2 BR PI0918726A2 BR PI0918726 A BRPI0918726 A BR PI0918726A BR PI0918726 A BRPI0918726 A BR PI0918726A BR PI0918726 A2 BRPI0918726 A2 BR PI0918726A2
Authority
BR
Brazil
Prior art keywords
tinnitus
amino
treatment
cognitive impairment
alkylcyclohexane derivatives
Prior art date
Application number
BRPI0918726A
Other languages
English (en)
Inventor
Barbara Ellers-Lenz
Hagen Krueger
Michael Althaus
Roman Goertelmeyer
Tanja Rosenberg
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of BRPI0918726A2 publication Critical patent/BRPI0918726A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0918726A 2008-09-10 2009-09-02 derivados de 1-amino-alquilciclohexano para o tratamento de deficiência cognitiva em tinido BRPI0918726A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19162608P 2008-09-10 2008-09-10
EP08015947 2008-09-10
PCT/EP2009/006366 WO2010028769A1 (en) 2008-09-10 2009-09-02 1-amino-alkylcyclohexane derivatives for the treatment of cognitive impairment in tinnitus

Publications (1)

Publication Number Publication Date
BRPI0918726A2 true BRPI0918726A2 (pt) 2015-12-01

Family

ID=40342435

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0918726A BRPI0918726A2 (pt) 2008-09-10 2009-09-02 derivados de 1-amino-alquilciclohexano para o tratamento de deficiência cognitiva em tinido

Country Status (13)

Country Link
US (1) US20110178179A1 (pt)
EP (1) EP2344144A1 (pt)
JP (1) JP2012501304A (pt)
KR (1) KR20110050739A (pt)
CN (1) CN102123703A (pt)
AU (1) AU2009291244A1 (pt)
BR (1) BRPI0918726A2 (pt)
CA (1) CA2731660A1 (pt)
IL (1) IL211641A0 (pt)
MX (1) MX2011002481A (pt)
RU (1) RU2011113733A (pt)
WO (1) WO2010028769A1 (pt)
ZA (1) ZA201101174B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2548552B1 (en) * 2007-09-12 2015-11-18 Merz Pharma GmbH & Co. KGaA Titration package for 1-amino-alkylcyclohexanes
US20150374705A1 (en) 2012-02-14 2015-12-31 Shanghai Institues for Biological Sciences Substances for treatment or relief of pain
CN106535883A (zh) * 2014-04-28 2017-03-22 杏林制药株式会社 耳鸣患者的治疗用药剂
WO2020163588A1 (en) * 2019-02-08 2020-08-13 Board Of Trustees Of Southern Illinois University Neuronal nicotinic acetylcholine receptor partial agonists as therapeutics for chronic tinnitus

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200418446A (en) * 2002-10-24 2004-10-01 Merz Pharma Gmbh & Co Kgaa Combination therapy using 1-aminocyclohexane derivatives and acetylcholinesterase inhibitors
US20060002999A1 (en) * 2004-06-17 2006-01-05 Forest Laboratories, Inc. Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane
US20070123555A1 (en) * 2005-09-30 2007-05-31 Cypress Bioscience, Inc. Prevention and treatment of hearing disorders
US20070141148A1 (en) * 2005-11-30 2007-06-21 Merz Pharma Gmbh & Co. Kgaa Neramexane MR matrix tablet

Also Published As

Publication number Publication date
IL211641A0 (en) 2011-05-31
CN102123703A (zh) 2011-07-13
RU2011113733A (ru) 2012-10-20
AU2009291244A1 (en) 2010-03-18
CA2731660A1 (en) 2010-03-18
EP2344144A1 (en) 2011-07-20
US20110178179A1 (en) 2011-07-21
WO2010028769A1 (en) 2010-03-18
JP2012501304A (ja) 2012-01-19
KR20110050739A (ko) 2011-05-16
ZA201101174B (en) 2011-10-26
MX2011002481A (es) 2011-04-26

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]