BRPI0918842A2 - método para tratar pacientes com esclerose múltipla com anticorpos anti-il2r - Google Patents

método para tratar pacientes com esclerose múltipla com anticorpos anti-il2r

Info

Publication number
BRPI0918842A2
BRPI0918842A2 BRPI0918842A BRPI0918842A BRPI0918842A2 BR PI0918842 A2 BRPI0918842 A2 BR PI0918842A2 BR PI0918842 A BRPI0918842 A BR PI0918842A BR PI0918842 A BRPI0918842 A BR PI0918842A BR PI0918842 A2 BRPI0918842 A2 BR PI0918842A2
Authority
BR
Brazil
Prior art keywords
multiple sclerosis
treating multiple
sclerosis patients
il2r antibodies
il2r
Prior art date
Application number
BRPI0918842A
Other languages
English (en)
Inventor
Randy R Robinson
Original Assignee
Abbott Biotherapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Biotherapeutics Corp filed Critical Abbott Biotherapeutics Corp
Publication of BRPI0918842A2 publication Critical patent/BRPI0918842A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
BRPI0918842A 2008-08-28 2009-08-28 método para tratar pacientes com esclerose múltipla com anticorpos anti-il2r BRPI0918842A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19036208P 2008-08-28 2008-08-28
PCT/US2009/055294 WO2010025321A2 (en) 2008-08-28 2009-08-28 Method for treating multiple sclerosis patients with anti-il2r antibodies

Publications (1)

Publication Number Publication Date
BRPI0918842A2 true BRPI0918842A2 (pt) 2015-12-08

Family

ID=41581181

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0918842A BRPI0918842A2 (pt) 2008-08-28 2009-08-28 método para tratar pacientes com esclerose múltipla com anticorpos anti-il2r

Country Status (7)

Country Link
US (1) US20100055098A1 (pt)
EP (1) EP2318437A2 (pt)
AU (1) AU2009285625A1 (pt)
BR (1) BRPI0918842A2 (pt)
CA (1) CA2730909A1 (pt)
RU (1) RU2011111391A (pt)
WO (1) WO2010025321A2 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010126890A1 (en) * 2009-04-27 2010-11-04 Facet Biotech Corporation Methods for monitoring the efficacy of anti-il-2r antibodies in multiple sclerosis patients
CA2771335A1 (en) * 2009-08-31 2011-03-03 Abbott Biotherapeutics Corp. Use of an immunoregulatory nk cell population for monitoring the efficacy of anti-il-2r antibodies in multiple sclerosis patients
EP2470901A1 (en) * 2009-10-30 2012-07-04 Abbott Biotherapeutics Corp. Use of immunoregulatory nk cell populations for predicting the efficacy of anti-il-2r antibodies in multiple sclerosis patients
JP6055615B2 (ja) 2011-05-27 2016-12-27 アッヴィ バイオテクノロジー リミテッド Dachyp組成物および方法
CA2844662A1 (en) * 2011-08-08 2013-02-14 Abbvie Biotherapeutics Inc. Methods of treating progressive forms of multiple sclerosis
AU2016341529B2 (en) 2015-10-22 2023-03-30 Juno Therapeutics Gmbh Methods for culturing cells and kits and apparatus for same
WO2018106945A1 (en) 2016-12-07 2018-06-14 Progenity Inc. Gastrointestinal tract detection methods, devices and systems
WO2018183929A1 (en) 2017-03-30 2018-10-04 Progenity Inc. Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device
RU2721282C2 (ru) * 2017-11-21 2020-05-18 Илья Владимирович Духовлинов Способ лечения рассеянного склероза (варианты)
WO2019246312A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immunomodulator
WO2019246317A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease or condition in a tissue originating from the endoderm
EP3883635A1 (en) 2018-11-19 2021-09-29 Progenity, Inc. Methods and devices for treating a disease with biotherapeutics
CN115666704B (zh) 2019-12-13 2025-09-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置
CN114805586A (zh) * 2022-04-14 2022-07-29 天津华科泰生物技术有限公司 抗MxA单克隆抗体组合物及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5336489A (en) * 1985-09-05 1994-08-09 The Beth Israel Hospital Association Treatment of allograft rejection with IL-2 receptor-specific cytotoxins
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
JPH05244982A (ja) * 1991-12-06 1993-09-24 Sumitomo Chem Co Ltd 擬人化b−b10
US6013256A (en) * 1996-09-24 2000-01-11 Protein Design Labs, Inc. Method of preventing acute rejection following solid organ transplantation
WO2004089973A2 (en) * 1997-01-23 2004-10-21 Epimmune Inc. Peptides, polypeptides, and proteins of reduced immunogenicity and methods for their production
US6346247B1 (en) * 1999-10-28 2002-02-12 Promega Corporation Prevention and treatment of autoimmune disease with luminally administered polyclonal antibodies
AU2002368055B2 (en) * 2002-06-28 2008-09-18 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method of treating autoimmune diseases with interferon-beta and IL-2R antagonist
WO2006042101A1 (en) * 2004-10-06 2006-04-20 The Government Of The United States As Represented By The Secretary Of Health And Human Services Method for treating active uveitis

Also Published As

Publication number Publication date
EP2318437A2 (en) 2011-05-11
AU2009285625A1 (en) 2010-03-04
CA2730909A1 (en) 2010-03-04
RU2011111391A (ru) 2012-10-10
WO2010025321A2 (en) 2010-03-04
WO2010025321A3 (en) 2010-05-20
US20100055098A1 (en) 2010-03-04

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]