BRPI0918964A2 - derivados de oxazolidinona com amidoxima cíclica ou amidrazona cíclica e composições farmacéuticas dos mesmos. - Google Patents
derivados de oxazolidinona com amidoxima cíclica ou amidrazona cíclica e composições farmacéuticas dos mesmos.Info
- Publication number
- BRPI0918964A2 BRPI0918964A2 BRPI0918964A BRPI0918964A BRPI0918964A2 BR PI0918964 A2 BRPI0918964 A2 BR PI0918964A2 BR PI0918964 A BRPI0918964 A BR PI0918964A BR PI0918964 A BRPI0918964 A BR PI0918964A BR PI0918964 A2 BRPI0918964 A2 BR PI0918964A2
- Authority
- BR
- Brazil
- Prior art keywords
- cyclic
- pharmaceutical compositions
- amidrazone
- amidoxime
- oxazolidinone derivatives
- Prior art date
Links
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical class O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title 1
- SFZULDYEOVSIKM-UHFFFAOYSA-N chembl321317 Chemical compound C1=CC(C(=N)NO)=CC=C1C1=CC=C(C=2C=CC(=CC=2)C(=N)NO)O1 SFZULDYEOVSIKM-UHFFFAOYSA-N 0.000 title 1
- -1 cyclic amidrazone Chemical class 0.000 title 1
- 125000004122 cyclic group Chemical group 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing alicyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2008-0093712 | 2008-09-24 | ||
| KR1020080093712A KR101023174B1 (ko) | 2008-09-24 | 2008-09-24 | 사이클릭 아미독심 또는 사이클릭 아미드라존 기를 가지는 신규한 옥사졸리디논 유도체 및 이를 함유하는 의약 조성물 |
| PCT/KR2009/005376 WO2010036000A2 (en) | 2008-09-24 | 2009-09-22 | Novel oxazolidinone derivatives with cyclic amidoxime or cyclic amidrazone and pharmaceutical compositions thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0918964A2 true BRPI0918964A2 (pt) | 2015-12-01 |
| BRPI0918964B1 BRPI0918964B1 (pt) | 2021-08-03 |
Family
ID=42060254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0918964-5A BRPI0918964B1 (pt) | 2008-09-24 | 2009-09-22 | Derivados de oxazolidinona com amidoxima cíclica ou amidrazona cíclica e composições farmacéuticas dos mesmos. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8242113B2 (pt) |
| EP (1) | EP2331529B1 (pt) |
| JP (1) | JP5511824B2 (pt) |
| KR (1) | KR101023174B1 (pt) |
| CN (1) | CN102171207B (pt) |
| AU (1) | AU2009297294B2 (pt) |
| BR (1) | BRPI0918964B1 (pt) |
| CA (1) | CA2737299C (pt) |
| ES (1) | ES2526120T3 (pt) |
| MX (1) | MX2011003118A (pt) |
| RU (1) | RU2468023C1 (pt) |
| WO (1) | WO2010036000A2 (pt) |
| ZA (1) | ZA201101894B (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101128029B1 (ko) | 2010-03-08 | 2012-03-29 | 주식회사 레고켐 바이오사이언스 | (ｒ)-3-(3-플루오로-4-(1-메틸-5,6-다이하이드로-1,2,4-트리아진-4(1ｈ)-일)페닐)-5-(치환된 메틸)옥사졸리딘-2-온 유도체의 제조방법 |
| WO2012121424A1 (ko) * | 2011-03-04 | 2012-09-13 | (주)레고켐바이오사이언스 | 사이클릭 아미드라존 기를 가지는 신규한 옥사졸리디논 유도체 및 이를 함유하는 의약 조성물 |
| KR101653570B1 (ko) * | 2011-03-30 | 2016-09-02 | 주식회사 레고켐 바이오사이언스 | 신규한 옥사졸리디논 유도체 및 이를 함유하는 의약 조성물 |
| US10583668B2 (en) | 2018-08-07 | 2020-03-10 | Markem-Imaje Corporation | Symbol grouping and striping for wide field matrix laser marking |
| KR102894590B1 (ko) | 2020-06-18 | 2025-12-03 | 아카제라 메디신즈, 인크. | 옥사졸리디논 화합물, 옥사졸리디논 화합물을 포함하는 리포좀 조성물 및 이의 사용 방법 |
| CN115702900B (zh) * | 2021-08-09 | 2024-02-09 | 上海纳为生物技术有限公司 | 一种rmx2001制剂组合物 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4128654A (en) * | 1978-02-10 | 1978-12-05 | E. I. Du Pont De Nemours And Company | 5-Halomethyl-3-phenyl-2-oxazolidinones |
| CA1320730C (en) * | 1987-10-16 | 1993-07-27 | The Du Pont Merck Pharmaceutical Company | Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents |
| US4948801A (en) * | 1988-07-29 | 1990-08-14 | E. I. Du Pont De Nemours And Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
| MY115155A (en) * | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
| EP0730591B1 (en) * | 1993-11-22 | 1999-07-14 | PHARMACIA & UPJOHN COMPANY | Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones |
| SK283487B6 (sk) * | 1995-09-01 | 2003-08-05 | Pharmacia And Upjohn Company | Fenyloxazolidinóny majúce C-C väzbu v 4 až 8 členných heterocyklických kruhoch |
| DE19962924A1 (de) * | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| KR100713170B1 (ko) * | 2001-03-07 | 2007-05-02 | 동아제약주식회사 | 헤테로고리 또는 헤테로아로마틱 고리가 치환된 피리딘고리를 포함하는 옥사졸리디논 유도체 및 그의 제조방법 |
| BR0111280A (pt) | 2000-06-05 | 2003-06-10 | Dong A Pharm Co Ltd | Novos derivados de oxazolidinona e um processo para a preparação dos mesmos |
| KR100674096B1 (ko) * | 2000-06-05 | 2007-01-26 | 동아제약주식회사 | 피리미딘 고리를 포함하는 신규 옥사졸리디논 유도체와그의 제조방법 |
| KR100856745B1 (ko) * | 2002-10-18 | 2008-09-04 | 동아제약주식회사 | 헤테로 고리 및 헤테로아로마틱 고리가 치환 또는 융합된피리딘을 포함하는 옥사졸리디논 유도체 및 그의 제조방법 |
| MXPA06013540A (es) * | 2004-05-25 | 2007-01-26 | Astrazeneca Ab | Derivados de 3-(4-(2 -dihidroisoxasol -3-ilpiridin-5-il) fenil)-5- triazol-1- ilmetiloxazolidin -2-ona como inhibidores de mao para el tratamiento de infecciones bacterianas. |
| KR100636961B1 (ko) * | 2005-02-17 | 2006-10-19 | 한미약품 주식회사 | 아졸이 치환된 옥사졸리디논 유도체 및 이의 제조 방법 |
| KR100872059B1 (ko) * | 2007-02-21 | 2008-12-05 | 주식회사 레고켐 바이오사이언스 | 아미독심 또는 하이드록사마이드 기를 가지는 신규한옥사졸리디논 유도체 및 이를 함유하는 의약 조성물 |
| KR100898361B1 (ko) * | 2008-07-03 | 2009-05-20 | 주식회사 레고켐 바이오사이언스 | Ｐ4 위치에 사이클릭 아미독심 또는 사이클릭 아미드라존기를 가지는 ＦＸａ 저해제, 이의 유도체, 제조방법 및이를 함유하는 의약 조성물 |
-
2008
- 2008-09-24 KR KR1020080093712A patent/KR101023174B1/ko active Active
-
2009
- 2009-09-22 BR BRPI0918964-5A patent/BRPI0918964B1/pt active IP Right Grant
- 2009-09-22 JP JP2011527752A patent/JP5511824B2/ja active Active
- 2009-09-22 CN CN200980137678.1A patent/CN102171207B/zh not_active Expired - Fee Related
- 2009-09-22 MX MX2011003118A patent/MX2011003118A/es active IP Right Grant
- 2009-09-22 US US13/120,568 patent/US8242113B2/en active Active
- 2009-09-22 CA CA2737299A patent/CA2737299C/en active Active
- 2009-09-22 EP EP09816393.4A patent/EP2331529B1/en active Active
- 2009-09-22 RU RU2011116164/04A patent/RU2468023C1/ru active
- 2009-09-22 ES ES09816393.4T patent/ES2526120T3/es active Active
- 2009-09-22 WO PCT/KR2009/005376 patent/WO2010036000A2/en not_active Ceased
- 2009-09-22 AU AU2009297294A patent/AU2009297294B2/en active Active
-
2011
- 2011-03-11 ZA ZA2011/01894A patent/ZA201101894B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN102171207A (zh) | 2011-08-31 |
| CA2737299A1 (en) | 2010-04-01 |
| CA2737299C (en) | 2014-04-01 |
| EP2331529B1 (en) | 2014-11-05 |
| BRPI0918964B1 (pt) | 2021-08-03 |
| JP5511824B2 (ja) | 2014-06-04 |
| KR101023174B1 (ko) | 2011-03-18 |
| WO2010036000A3 (en) | 2010-07-15 |
| US8242113B2 (en) | 2012-08-14 |
| AU2009297294A1 (en) | 2010-04-01 |
| EP2331529A2 (en) | 2011-06-15 |
| US20110178293A1 (en) | 2011-07-21 |
| ES2526120T3 (es) | 2015-01-07 |
| RU2468023C1 (ru) | 2012-11-27 |
| ZA201101894B (en) | 2012-07-25 |
| AU2009297294B2 (en) | 2013-10-31 |
| EP2331529A4 (en) | 2011-10-19 |
| WO2010036000A2 (en) | 2010-04-01 |
| CN102171207B (zh) | 2014-04-16 |
| MX2011003118A (es) | 2011-07-20 |
| JP2012503599A (ja) | 2012-02-09 |
| KR20100034522A (ko) | 2010-04-01 |
| RU2011116164A (ru) | 2012-10-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: A CLASSIFICACAO ANTERIOR ERA: C07D 403/08 Ipc: C07D 403/08 (2006.01), A61P 31/00 (2006.01), A61P |
|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 22/09/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO. |