BRPI0920082A2 - forma de dosagem oral de acetaminofeno/tramadol com liberação estendida. - Google Patents

forma de dosagem oral de acetaminofeno/tramadol com liberação estendida.

Info

Publication number: BRPI0920082A2
Authority: BR; Brazil
Prior art keywords: tramadol; dosage form; oral dosage; extended release; release acetaminophen
Prior art date: 2008-10-27

Application number

BRPI0920082A

Other languages

English (en)

Inventor

Ho Lee Domg

Hyun Kim Jae

Dong Liang-Chang

Joo Hwang Sung

Choi Tae-Hong

Wei-Guo-Dai

Original Assignee

Alza Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-10-27

Filing date

2009-10-23

Publication date

2019-09-24

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41514164&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0920082(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-10-23 Application filed by Alza Corp filed Critical Alza Corp

2019-09-24 Publication of BRPI0920082A2 publication Critical patent/BRPI0920082A2/pt

Links

229940056133 acetaminophen / tramadol Drugs 0.000 title 1
238000013265 extended release Methods 0.000 title 1
239000006186 oral dosage form Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Emergency Medicine (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Orthopedic Medicine & Surgery (AREA)
Neurosurgery (AREA)
Immunology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

BRPI0920082A 2008-10-27 2009-10-23 forma de dosagem oral de acetaminofeno/tramadol com liberação estendida. BRPI0920082A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US10861808P	2008-10-27	2008-10-27
PCT/US2009/061803 WO2010062524A1 (en)	2008-10-27	2009-10-23	Extended release oral acetaminophen/tramadol dosage form

Publications (1)

Publication Number	Publication Date
BRPI0920082A2 true BRPI0920082A2 (pt)	2019-09-24

Family

ID=41514164

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0920082A BRPI0920082A2 (pt)	2008-10-27	2009-10-23	forma de dosagem oral de acetaminofeno/tramadol com liberação estendida.

Country Status (25)

Country	Link
US (1)	US20100104638A1 (pt)
EP (1)	EP2362768B1 (pt)
JP (1)	JP5713911B2 (pt)
KR (3)	KR101631140B1 (pt)
CN (2)	CN102264355A (pt)
AU (1)	AU2009320181B2 (pt)
BR (1)	BRPI0920082A2 (pt)
CA (1)	CA2741751C (pt)
CL (1)	CL2011000935A1 (pt)
CO (1)	CO6331423A2 (pt)
CR (1)	CR20110287A (pt)
EA (1)	EA023149B1 (pt)
EC (1)	ECSP11011009A (pt)
ES (1)	ES2582779T3 (pt)
HN (1)	HN2011001184A (pt)
IL (1)	IL212453A (pt)
MX (1)	MX339867B (pt)
MY (1)	MY161550A (pt)
NI (1)	NI201100079A (pt)
NZ (1)	NZ592325A (pt)
PE (1)	PE20110855A1 (pt)
TW (1)	TWI561257B (pt)
UA (1)	UA102706C2 (pt)
WO (1)	WO2010062524A1 (pt)
ZA (1)	ZA201103880B (pt)

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US7776314B2 (en)	2002-06-17	2010-08-17	Grunenthal Gmbh	Abuse-proofed dosage system
DE10336400A1 (de)	2003-08-06	2005-03-24	Grünenthal GmbH	Gegen Missbrauch gesicherte Darreichungsform
DE10361596A1 (de)	2003-12-24	2005-09-29	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
US20070048228A1 (en)	2003-08-06	2007-03-01	Elisabeth Arkenau-Maric	Abuse-proofed dosage form
DE102005005446A1 (de)	2005-02-04	2006-08-10	Grünenthal GmbH	Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE102004032049A1 (de)	2004-07-01	2006-01-19	Grünenthal GmbH	Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de)	2005-02-04	2006-08-10	Grünenthal GmbH	Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
TWI454288B (zh)	2008-01-25	2014-10-01	Gruenenthal Chemie	藥物劑型
ES2599031T3 (es)	2008-05-09	2017-01-31	Grünenthal GmbH	Proceso para la preparación de una formulación de polvo intermedia y una forma de dosificación solida final utilizando un paso de congelación por pulverización
BR112012001466A2 (pt) *	2009-07-22	2020-08-11	Grünenthal GmbH	forma de dosagem resistente à falsificação para opioides sensíveis à oxidação, seu processo de fabricação, e embalagem
ES2534908T3 (es)	2009-07-22	2015-04-30	Grünenthal GmbH	Forma de dosificación de liberación controlada extruida por fusión en caliente
CA2808219C (en)	2010-09-02	2019-05-14	Gruenenthal Gmbh	Tamper resistant dosage form comprising inorganic salt
WO2012028318A1 (en)	2010-09-02	2012-03-08	Grünenthal GmbH	Tamper resistant dosage form comprising an anionic polymer
BR112013028668A2 (pt) *	2011-05-06	2017-01-24	Glaxosmithkline Llc	formulações de paracetamol de liberação sustentada
US10702485B2 (en)	2011-07-09	2020-07-07	Syntrix Biosystems Inc.	Compositions and methods for overcoming resistance to tramadol
JP6063462B2 (ja)	2011-07-29	2017-01-18	グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング	即時薬剤放出を提供するタンパーレジスタント錠剤
BR112014002022A2 (pt)	2011-07-29	2017-02-21	Gruenenthal Gmbh	comprimido resistente à violação proporcionando liberação de fármaco imediata
BR112014019988A8 (pt)	2012-02-28	2017-07-11	Gruenenthal Gmbh	Forma de dosagem resistente a socamento compreendendo um composto farmacologicamente ativo e um polímero aniônico
LT2838512T (lt)	2012-04-18	2018-11-12	GrĆ¼nenthal GmbH	Pažeidimui atspari ir dozės atpalaidavimo nuokrypiui atspari farmacinė vaisto forma
WO2013169977A2 (en) *	2012-05-10	2013-11-14	Fmc Corporation	Controlled release solid dose form
US10064945B2 (en)	2012-05-11	2018-09-04	Gruenenthal Gmbh	Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
AU2014273227B2 (en)	2013-05-29	2019-08-15	Grunenthal Gmbh	Tamper-resistant dosage form containing one or more particles
MX2015016254A (es)	2013-05-29	2016-04-20	Gruenenthal Gmbh	Forma de dosificacion resistente al uso indebido con perfil de liberacion bimodal.
DE102013009114A1 (de)	2013-05-29	2014-12-04	Franz Gerstheimer	Pharmazeutische Zusammensetzung zur Überwindung von Metabolisierungsproblemen
AU2014289187B2 (en)	2013-07-12	2019-07-11	Grunenthal Gmbh	Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
WO2015044952A2 (en) *	2013-09-30	2015-04-02	Athena Drug Delivery Solutions Pvt Ltd.	Tramadol hydrochloride and paracetamol orally disintegrating composition and process for preparing the same
HK1224189A1 (zh)	2013-11-26	2017-08-18	Grünenthal GmbH	通过低温研磨制备粉状药物组合物
WO2015088990A1 (en)	2013-12-09	2015-06-18	Durect Corporation	Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
CA2933983A1 (en) *	2013-12-16	2015-06-25	Grunenthal Gmbh	Tamper resistant dosage form with bimodal release profile manufactured by co-extrusion
WO2015173195A1 (en)	2014-05-12	2015-11-19	Grünenthal GmbH	Tamper resistant immediate release capsule formulation comprising tapentadol
US9872835B2 (en)	2014-05-26	2018-01-23	Grünenthal GmbH	Multiparticles safeguarded against ethanolic dose-dumping
WO2016170097A1 (en)	2015-04-24	2016-10-27	Grünenthal GmbH	Tamper-resistant dosage form with immediate release and resistance against solvent extraction
CA2998259A1 (en)	2015-09-10	2017-03-16	Grunenthal Gmbh	Protecting oral overdose with abuse deterrent immediate release formulations
GB2567493B (en)	2017-10-13	2019-12-18	Altus Formulation Inc	Starch-based release modifying excipients and pharmaceutical compositions derived therefrom
US11000488B2 (en)	2019-03-22	2021-05-11	Syntrix Biosystems Inc.	Treating pain using desmetramadol
KR20240027436A (ko) *	2022-08-23	2024-03-04	대원제약주식회사	펠루비프로펜 및 트라마돌의 이온결합 화합물, 이를 포함하는 조성물, 및 이의 제조 방법
KR20240158668A (ko) *	2023-04-27	2024-11-05	대원제약주식회사	펠루비프로펜 및 트라마돌을 포함하는 진통용 약학적 조성물

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CA2173818A1 (fr) *	1996-04-10	1997-10-11	Francois Chouinard	Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose
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CN1785167A (zh) *	2005-10-08	2006-06-14	王鸣	一种非麻醉性镇痛剂的复方缓释制剂的制备方法
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WO2009114648A1 (en) *	2008-03-11	2009-09-17	Depomed Inc.	Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic

2009
- 2009-10-23 AU AU2009320181A patent/AU2009320181B2/en not_active Ceased
- 2009-10-23 KR KR1020137031476A patent/KR101631140B1/ko not_active Expired - Fee Related
- 2009-10-23 WO PCT/US2009/061803 patent/WO2010062524A1/en not_active Ceased
- 2009-10-23 EP EP09740619.3A patent/EP2362768B1/en active Active
- 2009-10-23 KR KR1020117024463A patent/KR20110119845A/ko not_active Ceased
- 2009-10-23 NZ NZ592325A patent/NZ592325A/xx not_active IP Right Cessation
- 2009-10-23 JP JP2011534641A patent/JP5713911B2/ja not_active Expired - Fee Related
- 2009-10-23 CN CN2009801536507A patent/CN102264355A/zh active Pending
- 2009-10-23 KR KR1020117004791A patent/KR20110036858A/ko not_active Ceased
- 2009-10-23 PE PE2011000940A patent/PE20110855A1/es not_active Application Discontinuation
- 2009-10-23 MX MX2011004403A patent/MX339867B/es active IP Right Grant
- 2009-10-23 EA EA201170616A patent/EA023149B1/ru not_active IP Right Cessation
- 2009-10-23 BR BRPI0920082A patent/BRPI0920082A2/pt not_active IP Right Cessation
- 2009-10-23 CA CA2741751A patent/CA2741751C/en not_active Expired - Fee Related
- 2009-10-23 MY MYPI2011001827A patent/MY161550A/en unknown
- 2009-10-23 ES ES09740619.3T patent/ES2582779T3/es active Active
- 2009-10-23 US US12/604,560 patent/US20100104638A1/en not_active Abandoned
- 2009-10-23 CN CN201610873739.2A patent/CN107028908A/zh active Pending
- 2009-10-23 UA UAA201106620A patent/UA102706C2/ru unknown
- 2009-10-26 TW TW098136097A patent/TWI561257B/zh not_active IP Right Cessation
2011
- 2011-04-26 IL IL212453A patent/IL212453A/en not_active IP Right Cessation
- 2011-04-26 CO CO11050889A patent/CO6331423A2/es not_active Application Discontinuation
- 2011-04-26 CL CL2011000935A patent/CL2011000935A1/es unknown
- 2011-04-27 EC EC2011011009A patent/ECSP11011009A/es unknown
- 2011-04-27 HN HN2011001184A patent/HN2011001184A/es unknown
- 2011-04-27 NI NI201100079A patent/NI201100079A/es unknown
- 2011-05-26 ZA ZA2011/03880A patent/ZA201103880B/en unknown
- 2011-05-27 CR CR20110287A patent/CR20110287A/es unknown

Also Published As

Publication number	Publication date
UA102706C2 (ru)	2013-08-12
CO6331423A2 (es)	2011-10-20
ES2582779T3 (es)	2016-09-15
KR20110119845A (ko)	2011-11-02
CN107028908A (zh)	2017-08-11
EP2362768B1 (en)	2016-04-20
NI201100079A (es)	2011-10-21
MY161550A (en)	2017-04-28
TWI561257B (en)	2016-12-11
CR20110287A (es)	2011-11-10
JP2012506907A (ja)	2012-03-22
KR101631140B1 (ko)	2016-06-20
KR20130137720A (ko)	2013-12-17
ZA201103880B (en)	2012-10-31
NZ592325A (en)	2012-09-28
EA201170616A1 (ru)	2011-12-30
TW201028180A (en)	2010-08-01
AU2009320181B2 (en)	2015-08-27
WO2010062524A1 (en)	2010-06-03
MX339867B (es)	2016-06-14
PE20110855A1 (es)	2011-12-05
IL212453A (en)	2017-03-30
CA2741751C (en)	2017-05-09
CN102264355A (zh)	2011-11-30
US20100104638A1 (en)	2010-04-29
KR20110036858A (ko)	2011-04-11
EA023149B1 (ru)	2016-04-29
JP5713911B2 (ja)	2015-05-07
EP2362768A1 (en)	2011-09-07
MX2011004403A (es)	2011-05-25
HK1162915A1 (zh)	2012-09-07
ECSP11011009A (es)	2011-06-30
IL212453A0 (en)	2011-06-30
CL2011000935A1 (es)	2011-10-21
AU2009320181A1 (en)	2010-06-03
HN2011001184A (es)	2014-09-01
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