BRPI0921966A2 - levedura expressando celulases para sacarificação e fermentação simultâneas usando celulose. - Google Patents
levedura expressando celulases para sacarificação e fermentação simultâneas usando celulose.Info
- Publication number
- BRPI0921966A2 BRPI0921966A2 BRPI0921966A BRPI0921966A BRPI0921966A2 BR PI0921966 A2 BRPI0921966 A2 BR PI0921966A2 BR PI0921966 A BRPI0921966 A BR PI0921966A BR PI0921966 A BRPI0921966 A BR PI0921966A BR PI0921966 A2 BRPI0921966 A2 BR PI0921966A2
- Authority
- BR
- Brazil
- Prior art keywords
- fermentation
- cellulose
- simultaneous saccharification
- yeast expressing
- expressing cellulases
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
- C12P7/10—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2445—Beta-glucosidase (3.2.1.21)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P39/00—Processes involving microorganisms of different genera in the same process, simultaneously
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/14—Multiple stages of fermentation; Multiple types of microorganisms or re-use of microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01004—Cellulase (3.2.1.4), i.e. endo-1,4-beta-glucanase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01021—Beta-glucosidase (3.2.1.21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01091—Cellulose 1,4-beta-cellobiosidase (3.2.1.91)
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11698108P | 2008-11-21 | 2008-11-21 | |
| US61/116,981 | 2008-11-21 | ||
| PCT/US2009/065571 WO2010060056A2 (en) | 2008-11-21 | 2009-11-23 | Yeast expressing cellulases for simultaneous saccharification and fermentation using cellulose |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0921966A2 true BRPI0921966A2 (pt) | 2017-10-24 |
| BRPI0921966A8 BRPI0921966A8 (pt) | 2017-12-12 |
| BRPI0921966B1 BRPI0921966B1 (pt) | 2019-05-07 |
Family
ID=42198846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0921966-8A BRPI0921966B1 (pt) | 2008-11-21 | 2009-11-23 | Célula hospedeira de levedura termotolerante, método de fermentar celulose e cultura |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US9102955B2 (pt) |
| EP (1) | EP2361311B1 (pt) |
| CN (2) | CN108315272A (pt) |
| AU (1) | AU2009316309B2 (pt) |
| BR (1) | BRPI0921966B1 (pt) |
| CA (3) | CA2744495C (pt) |
| DK (1) | DK2361311T3 (pt) |
| ES (1) | ES2621181T3 (pt) |
| NZ (1) | NZ593469A (pt) |
| WO (1) | WO2010060056A2 (pt) |
Families Citing this family (61)
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| WO2009139839A1 (en) | 2008-05-11 | 2009-11-19 | Mascoma Corporation | Construction of protrophic/celluloytic yeast strains expressing tethered and secreted cellulases |
| ES2621181T3 (es) | 2008-11-21 | 2017-07-03 | Lallemand Hungary Liquidity Management Llc | Levaduras que expresan celulasas para la sacarificación y fermentación simultáneas utilizando celulosa |
| CN102666849A (zh) | 2009-10-26 | 2012-09-12 | 斯泰伦博斯大学 | 真菌纤维二糖水解酶2基因在酵母中的异源表达 |
| US20130071884A1 (en) | 2009-11-06 | 2013-03-21 | Agrivida, Inc. | Plants expressing cell wall degrading enzymes and expression vectors |
| WO2011140386A2 (en) | 2010-05-05 | 2011-11-10 | Mascoma Corporation | Detoxification of biomass derived acetate via metabolic conversion to ethanol, acetone, isopropanol, or ethyl acetate |
| EP2576762A4 (en) | 2010-06-03 | 2013-12-04 | Mascoma Corp | YEAST FOR THE EXPRESSION OF SACCHAROLYTIC ENZYMES FOR CONSOLIDATED BIOVERIC PROCESSING USING STARCH AND CELLULOSE |
| US10443068B2 (en) | 2010-06-25 | 2019-10-15 | Agrivida, Inc. | Plants with engineered endogenous genes |
| US9598700B2 (en) | 2010-06-25 | 2017-03-21 | Agrivida, Inc. | Methods and compositions for processing biomass with elevated levels of starch |
| ES2926521T3 (es) * | 2010-12-22 | 2022-10-26 | Neste Oyj | Un proceso integrado para producir biocombustibles |
| EP2668268B1 (en) | 2011-01-26 | 2017-05-31 | Novozymes A/S | Polypeptides having cellobiohydrolase activity and polynucleotides encoding same |
| MX2013007720A (es) | 2011-01-26 | 2013-08-09 | Novozymes As | Polipeptidos que tienen actividad celobiohidrolasa y polinucleotidos que codifican para los mismos. |
| AU2012225487B2 (en) | 2011-03-07 | 2017-04-06 | Agrivida, Inc. | Consolidated pretreatment and hydrolysis of plant biomass expressing cell wall degrading enzymes |
| CA2832279C (en) | 2011-04-05 | 2024-03-05 | Mascoma Corporation | Methods for the improvement of product yield and production in a microorganism through the addition of alternate electron acceptors |
| CN104039806A (zh) | 2011-11-10 | 2014-09-10 | 马斯科马公司 | 被加工为发酵木糖和阿拉伯糖的啤酒酵母的遗传修饰菌株 |
| US9708591B2 (en) | 2011-11-18 | 2017-07-18 | Novozymes Inc. | Polypeptides having endoglucanase activity and polynucleotides encoding same |
| US20140295475A1 (en) * | 2011-12-13 | 2014-10-02 | Danisco Us Inc. | Enzyme cocktails prepared from mixed cultures |
| BR112014015242B1 (pt) * | 2011-12-22 | 2023-01-31 | Novozymes, Inc | Polipeptídeo híbrido isolado, polinucleotídeo isolado,célula hospedeira, método de produção de um polipeptídeo híbrido, processos para degradação ou conversão de um material celulósico, para produção de um produto de fermentação, de fermentação de um material celulósico, formulação ou composição de cultura de células microbianas de caldo completo, e,célula hospedeira microbiana transgênica |
| JP2013169154A (ja) * | 2012-02-17 | 2013-09-02 | Toyota Motor Corp | セルロース系バイオマス分解増強活性ポリペプチド |
| US20140024064A1 (en) | 2012-07-23 | 2014-01-23 | Butamax(Tm) Advanced Biofuels Llc | Processes and systems for the production of fermentative alcohols |
| CN102851324A (zh) * | 2012-08-24 | 2013-01-02 | 太仓市周氏化学品有限公司 | 一种利用耐高温酵母同步糖化发酵产乙醇的方法 |
| BR112015005439A8 (pt) | 2012-09-12 | 2022-01-11 | Butamax Advanced Biofuels Llc | Método para recuperar um produto alcoólico de um caldo de fermentação e sistema |
| CA2887574A1 (en) | 2012-10-11 | 2014-04-17 | Butamax Advanced Biofuels Llc | Processes and systems for the production of fermentation products |
| MX2015005427A (es) * | 2012-10-31 | 2015-08-05 | Danisco Inc | Beta-glucosidasa de magnaporthe grisea. |
| WO2014070841A1 (en) * | 2012-10-31 | 2014-05-08 | Danisco Us Inc. | Compositions and methods of use |
| WO2014074895A2 (en) | 2012-11-09 | 2014-05-15 | Mascoma Corporation | Method for acetate consumption during ethanolic fermentation of cellulosic feedstocks |
| EP3290515A1 (en) | 2012-12-12 | 2018-03-07 | Danisco US Inc. | Variants of cellobiohydrolases |
| WO2014151805A2 (en) | 2013-03-15 | 2014-09-25 | Mascoma Corporation | Expression of beta-glucosidases for hydrolysis of lignocellulose and associated oligomers |
| US9850512B2 (en) | 2013-03-15 | 2017-12-26 | The Research Foundation For The State University Of New York | Hydrolysis of cellulosic fines in primary clarified sludge of paper mills and the addition of a surfactant to increase the yield |
| CN103409333B (zh) * | 2013-05-20 | 2015-01-28 | 山东大学 | 一株持续高效分泌β-葡萄糖苷酶的重组酿酒酵母菌株及其应用 |
| EP3453765A1 (en) * | 2013-06-12 | 2019-03-13 | Renescience A/S | Methods of processing municipal solid waste (msw) using microbial hydrolysis and fermentation and slurry resulting therefrom |
| DK3033413T4 (da) | 2013-08-15 | 2023-07-03 | Lallemand Hungary Liquidity Man Llc | Fremgangsmåder til forbedring af produktudbytte og produktion i en mikroorganisme gennem recirkulering af glycerol |
| WO2015042543A2 (en) * | 2013-09-20 | 2015-03-26 | The Trustees Of Columbia University In The City Of New York | Biofuel production enzymes and uses thereof |
| SG11201605046YA (en) | 2013-12-20 | 2016-07-28 | Hutchinson Fred Cancer Res | Tagged chimeric effector molecules and receptors thereof |
| CN103805673B (zh) * | 2014-03-01 | 2015-12-09 | 青岛科技大学 | 一种利用转基因酵母混合发酵生产秸秆乙醇的方法 |
| US9951363B2 (en) | 2014-03-14 | 2018-04-24 | The Research Foundation for the State University of New York College of Environmental Science and Forestry | Enzymatic hydrolysis of old corrugated cardboard (OCC) fines from recycled linerboard mill waste rejects |
| CN104046605A (zh) * | 2014-05-29 | 2014-09-17 | 中国科学院广州能源研究所 | 一种嗜温耐乙醇β-葡萄糖苷酶及其编码基因和应用 |
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| WO2016176652A2 (en) | 2015-04-29 | 2016-11-03 | Fred Hutchinson Cancer Research Center | Modified stem cells and uses thereof |
| US20180355318A1 (en) * | 2015-04-29 | 2018-12-13 | Fred Hutchinson Cancer Research Center | Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof |
| CN106086087B (zh) * | 2016-08-18 | 2025-08-26 | 吉林中之林农业科技有限公司 | 一种微生物共培养制备生物质单体的系统 |
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| EP3502126A1 (en) * | 2017-12-19 | 2019-06-26 | CIC nanoGUNE - Asociación Centro de Investigación Cooperativa en Nanociencias | Ancestral cellulases and uses thereof |
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| CN108823102B (zh) * | 2018-06-10 | 2021-09-03 | 东北农业大学 | 寒地秸秆腐熟真菌被孢霉菌株及其在水稻秸秆腐熟中的应用 |
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| CN118667828A (zh) * | 2024-05-23 | 2024-09-20 | 中国农业大学 | 自噬相关基因及其在玉米抗盐中的应用 |
| CN119799523B (zh) * | 2025-01-24 | 2026-02-06 | 佛山市海天(高明)调味食品有限公司 | 一株葡萄牙棒孢酵母yjht233及其应用 |
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| US5811381A (en) | 1996-10-10 | 1998-09-22 | Mark A. Emalfarb | Cellulase compositions and methods of use |
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2009
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- 2009-11-23 EP EP09828362.5A patent/EP2361311B1/en not_active Not-in-force
- 2009-11-23 CA CA2744495A patent/CA2744495C/en active Active
- 2009-11-23 CN CN201710766848.9A patent/CN108315272A/zh active Pending
- 2009-11-23 NZ NZ593469A patent/NZ593469A/xx not_active IP Right Cessation
- 2009-11-23 DK DK09828362.5T patent/DK2361311T3/en active
- 2009-11-23 CA CA2964245A patent/CA2964245C/en active Active
- 2009-11-23 US US13/130,549 patent/US9102955B2/en active Active
- 2009-11-23 CA CA3092340A patent/CA3092340A1/en active Pending
- 2009-11-23 AU AU2009316309A patent/AU2009316309B2/en not_active Ceased
- 2009-11-23 BR BRPI0921966-8A patent/BRPI0921966B1/pt active IP Right Grant
- 2009-11-23 WO PCT/US2009/065571 patent/WO2010060056A2/en not_active Ceased
- 2009-11-23 CN CN2009801537092A patent/CN102272303A/zh active Pending
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2015
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2018
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2020
- 2020-12-22 US US17/131,293 patent/US20210388398A1/en not_active Abandoned
Also Published As
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|---|---|
| NZ593469A (en) | 2012-12-21 |
| CA3092340A1 (en) | 2010-05-27 |
| CA2964245C (en) | 2020-10-27 |
| US20120129229A1 (en) | 2012-05-24 |
| US9988652B2 (en) | 2018-06-05 |
| BRPI0921966B1 (pt) | 2019-05-07 |
| EP2361311A4 (en) | 2013-03-27 |
| CA2744495A1 (en) | 2010-05-27 |
| CA2744495C (en) | 2017-05-30 |
| US20160010117A1 (en) | 2016-01-14 |
| CN108315272A (zh) | 2018-07-24 |
| WO2010060056A3 (en) | 2010-07-15 |
| BRPI0921966A8 (pt) | 2017-12-12 |
| US9102955B2 (en) | 2015-08-11 |
| EP2361311B1 (en) | 2017-01-18 |
| CN102272303A (zh) | 2011-12-07 |
| EP2361311A2 (en) | 2011-08-31 |
| WO2010060056A2 (en) | 2010-05-27 |
| AU2009316309A1 (en) | 2011-10-20 |
| US20180258449A1 (en) | 2018-09-13 |
| US20210388398A1 (en) | 2021-12-16 |
| DK2361311T3 (en) | 2017-04-24 |
| ES2621181T3 (es) | 2017-07-03 |
| AU2009316309B2 (en) | 2016-07-07 |
| CA2964245A1 (en) | 2010-05-27 |
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