BRPI0922083A2 - proteases compreendendo uma ou mais mutações combináveis - Google Patents
proteases compreendendo uma ou mais mutações combináveisInfo
- Publication number
- BRPI0922083A2 BRPI0922083A2 BRPI0922083A BRPI0922083A BRPI0922083A2 BR PI0922083 A2 BRPI0922083 A2 BR PI0922083A2 BR PI0922083 A BRPI0922083 A BR PI0922083A BR PI0922083 A BRPI0922083 A BR PI0922083A BR PI0922083 A2 BRPI0922083 A2 BR PI0922083A2
- Authority
- BR
- Brazil
- Prior art keywords
- proteases
- combinable mutations
- combinable
- mutations
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38609—Protease or amylase in solid compositions only
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38618—Protease or amylase in liquid compositions only
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38627—Preparations containing enzymes, e.g. protease or amylase containing lipase
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38636—Preparations containing enzymes, e.g. protease or amylase containing enzymes other than protease, amylase, lipase, cellulase, oxidase or reductase
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38645—Preparations containing enzymes, e.g. protease or amylase containing cellulase
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38654—Preparations containing enzymes, e.g. protease or amylase containing oxidase or reductase
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38663—Stabilised liquid enzyme compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38681—Chemically modified or immobilised enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21062—Subtilisin (3.4.21.62)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Detergent Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR122013014157-0A BR122013014157A2 (pt) | 2008-11-11 | 2009-11-10 | composições de limpeza compreendendo variantes de subtilisina de bacillus, bem como processo de limpeza |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11354508P | 2008-11-11 | 2008-11-11 | |
| US21880209P | 2009-06-19 | 2009-06-19 | |
| PCT/US2009/063837 WO2010056653A2 (en) | 2008-11-11 | 2009-11-10 | Proteases comprising one or more combinable mutations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0922083A2 true BRPI0922083A2 (pt) | 2017-05-30 |
Family
ID=41786712
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR122013014157-0A BR122013014157A2 (pt) | 2008-11-11 | 2009-11-10 | composições de limpeza compreendendo variantes de subtilisina de bacillus, bem como processo de limpeza |
| BRPI0922083A BRPI0922083A2 (pt) | 2008-11-11 | 2009-11-10 | proteases compreendendo uma ou mais mutações combináveis |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR122013014157-0A BR122013014157A2 (pt) | 2008-11-11 | 2009-11-10 | composições de limpeza compreendendo variantes de subtilisina de bacillus, bem como processo de limpeza |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US8753861B2 (pt) |
| EP (3) | EP2650354A3 (pt) |
| JP (3) | JP2012508031A (pt) |
| KR (1) | KR20110095260A (pt) |
| CN (4) | CN103122345A (pt) |
| AR (1) | AR074311A1 (pt) |
| BR (2) | BR122013014157A2 (pt) |
| CA (1) | CA2743302A1 (pt) |
| MX (1) | MX2011004802A (pt) |
| RU (1) | RU2560978C2 (pt) |
| WO (1) | WO2010056653A2 (pt) |
Families Citing this family (120)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2336092T3 (es) * | 2002-01-16 | 2010-04-08 | Genencor International, Inc. | Variantes de proteasas con multiples sustituciones. |
| US20090060933A1 (en) * | 2004-06-14 | 2009-03-05 | Estell David A | Proteases producing an altered immunogenic response and methods of making and using the same |
| US20090215663A1 (en) * | 2006-04-20 | 2009-08-27 | Novozymes A/S | Savinase variants having an improved wash performance on egg stains |
| US20100192985A1 (en) * | 2008-11-11 | 2010-08-05 | Wolfgang Aehle | Compositions and methods comprising serine protease variants |
| RU2560978C2 (ru) * | 2008-11-11 | 2015-08-20 | ДАНИСКО ЮЭс ИНК. | Протеазы, содержащие одну или несколько комбинируемых мутаций |
| PL2558573T3 (pl) * | 2010-04-15 | 2017-08-31 | Danisco Us Inc. | Kompozycje i sposoby obejmujące warianty proteazy |
| JP6448904B2 (ja) * | 2010-05-06 | 2019-01-09 | ダニスコ・ユーエス・インク | サブチリシン変異体を含む組成物及び方法 |
| EP2818543B8 (en) * | 2012-02-21 | 2018-03-07 | Bloomage Freda Biopharm Co., Ltd. | Bacillus, hyaluronic acid enzyme, and uses thereof |
| WO2014099525A1 (en) | 2012-12-21 | 2014-06-26 | Danisco Us Inc. | Paenibacillus curdlanolyticus amylase, and methods of use, thereof |
| CN104884614A (zh) | 2012-12-21 | 2015-09-02 | 丹尼斯科美国公司 | α-淀粉酶变体 |
| ES2676895T5 (es) | 2013-03-11 | 2022-04-27 | Danisco Us Inc | Variantes combinatorias de alfa-amilasa |
| WO2014173980A2 (en) * | 2013-04-23 | 2014-10-30 | Novozymes A/S | Liquid automatic dish washing detergent compositions |
| US20160108388A1 (en) | 2013-05-29 | 2016-04-21 | Danisco Us Inc. | Novel metalloproteases |
| EP3004342B1 (en) | 2013-05-29 | 2023-01-11 | Danisco US Inc. | Novel metalloproteases |
| WO2014194032A1 (en) | 2013-05-29 | 2014-12-04 | Danisco Us Inc. | Novel metalloproteases |
| WO2014194034A2 (en) | 2013-05-29 | 2014-12-04 | Danisco Us Inc. | Novel metalloproteases |
| CN104419651B (zh) * | 2013-08-19 | 2018-12-25 | 丰益(上海)生物技术研发中心有限公司 | 磷脂酶c及其产生菌株 |
| DE102013218253A1 (de) | 2013-09-12 | 2015-03-12 | Henkel Ag & Co. Kgaa | Festes Textilwaschmittel mit verbesserter Proteaseleistung |
| CN104560763B (zh) * | 2013-10-15 | 2018-12-25 | 丰益(上海)生物技术研发中心有限公司 | 产磷脂酶c的地衣芽孢杆菌及其产生的磷脂酶c |
| AR098006A1 (es) | 2013-10-15 | 2016-04-27 | Danisco Us Inc | Gránulo de arcilla |
| CN104560764B (zh) * | 2013-10-17 | 2018-12-25 | 丰益(上海)生物技术研发中心有限公司 | 产磷脂酶c的短小芽孢杆菌及其产生的磷脂酶c |
| HK1220221A1 (zh) | 2013-11-11 | 2017-04-28 | 艺康美国股份有限公司 | 多用途的酶洗涤剂和稳定使用溶液的方法 |
| BR112016010425B8 (pt) | 2013-11-11 | 2023-01-31 | Ecolab Usa Inc | Detergente concentrado para lavar utensílios e seu método de utilização |
| DK3068879T3 (da) | 2013-11-14 | 2020-03-16 | Danisco Us Inc | Stabile enzymer opnået ved glykeringsreduktion |
| DK3080262T3 (da) | 2013-12-13 | 2019-05-06 | Danisco Us Inc | Serinproteaser af bacillus-arter |
| EP3910057A1 (en) | 2013-12-13 | 2021-11-17 | Danisco US Inc. | Serine proteases of the bacillus gibsonii-clade |
| KR20160099629A (ko) | 2013-12-16 | 2016-08-22 | 이 아이 듀폰 디 네모아 앤드 캄파니 | 점도 조절제로서의 폴리 알파-1,3-글루칸 에테르의 사용 |
| ES2835703T3 (es) | 2013-12-18 | 2021-06-23 | Nutrition & Biosciences Usa 4 Inc | Eteres de poli alfa-1,3-glucano catiónicos |
| EP3097174A1 (en) | 2014-01-22 | 2016-11-30 | The Procter & Gamble Company | Method of treating textile fabrics |
| EP3097175B1 (en) | 2014-01-22 | 2018-10-17 | The Procter and Gamble Company | Fabric treatment composition |
| EP3097172A1 (en) | 2014-01-22 | 2016-11-30 | The Procter & Gamble Company | Method of treating textile fabrics |
| EP3097173B1 (en) | 2014-01-22 | 2020-12-23 | The Procter and Gamble Company | Fabric treatment composition |
| WO2015123323A1 (en) | 2014-02-14 | 2015-08-20 | E. I. Du Pont De Nemours And Company | Poly-alpha-1,3-1,6-glucans for viscosity modification |
| EP3116914B8 (en) | 2014-03-11 | 2021-04-21 | E. I. du Pont de Nemours and Company | Oxidized poly alpha-1,3-glucan as detergent builder |
| US20170096653A1 (en) | 2014-03-21 | 2017-04-06 | Danisco Us Inc. | Serine proteases of bacillus species |
| US9714403B2 (en) | 2014-06-19 | 2017-07-25 | E I Du Pont De Nemours And Company | Compositions containing one or more poly alpha-1,3-glucan ether compounds |
| EP3158043B1 (en) | 2014-06-19 | 2021-03-10 | Nutrition & Biosciences USA 4, Inc. | Compositions containing one or more poly alpha-1,3-glucan ether compounds |
| DK3207129T3 (da) | 2014-10-17 | 2020-02-24 | Danisco Us Inc | Serinproteaser af bacillus-arten |
| WO2016065238A1 (en) | 2014-10-24 | 2016-04-28 | Danisco Us Inc. | Method for producing alcohol by use of a tripeptidyl peptidase |
| DK3212662T3 (da) | 2014-10-27 | 2020-07-20 | Danisco Us Inc | Serinproteaser |
| EP3212783B1 (en) | 2014-10-27 | 2024-06-26 | Danisco US Inc. | Serine proteases |
| DK3212781T3 (da) | 2014-10-27 | 2019-12-16 | Danisco Us Inc | Serinproteaser |
| EP3957729A1 (en) | 2014-10-27 | 2022-02-23 | Danisco US Inc. | Serine proteases |
| CN107148472A (zh) | 2014-10-27 | 2017-09-08 | 丹尼斯科美国公司 | 芽孢杆菌属物种的丝氨酸蛋白酶 |
| BR112017010239A2 (pt) | 2014-11-17 | 2018-01-02 | Procter & Gamble | composições para liberação de agente de benefício |
| EP4530348A3 (en) * | 2014-12-15 | 2025-08-06 | Basf Se | Detergent composition comprising subtilase variants |
| WO2016096711A2 (en) | 2014-12-15 | 2016-06-23 | Novozymes A/S | Subtilase variants |
| CN108064306B (zh) | 2014-12-23 | 2022-11-01 | 营养与生物科学美国4公司 | 酶促产生的纤维素 |
| HUE039080T2 (hu) | 2015-04-29 | 2018-12-28 | Procter & Gamble | Textilkezelési módszer |
| DK3088506T3 (en) | 2015-04-29 | 2018-08-13 | Procter & Gamble | detergent |
| DK3088505T3 (da) | 2015-04-29 | 2020-08-03 | Procter & Gamble | Fremgangsmåde til behandling af et tekstilstof |
| EP3088504B1 (en) | 2015-04-29 | 2021-07-21 | The Procter & Gamble Company | Method of treating a fabric |
| CN107532116B (zh) | 2015-04-29 | 2021-05-07 | 宝洁公司 | 处理织物的方法 |
| CN107835855B (zh) | 2015-05-13 | 2022-05-13 | 丹尼斯科美国公司 | AprL-进化枝蛋白酶变体及其用途 |
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| FI3307427T3 (fi) | 2015-06-09 | 2023-11-09 | Danisco Us Inc | Osmoottiset puhkeavat kapselit |
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| EP4141113A1 (en) | 2015-11-05 | 2023-03-01 | Danisco US Inc | Paenibacillus sp. mannanases |
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| JP7045313B2 (ja) | 2015-11-13 | 2022-03-31 | ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー,インコーポレイテッド | 洗濯ケアおよび織物ケアにおいて使用するためのグルカン繊維組成物 |
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| WO2017173240A1 (en) | 2016-03-31 | 2017-10-05 | Gojo Industries, Inc. | Antimicrobial peptide stimulating cleansing composition |
| EP3436041B1 (en) | 2016-03-31 | 2023-05-24 | Gojo Industries, Inc. | Sanitizer composition with probiotic/prebiotic active ingredient |
| DE102016205670A1 (de) | 2016-04-06 | 2017-10-12 | Henkel Ag & Co. Kgaa | Neue Protease mit verbesserter Waschleistung |
| WO2017210295A1 (en) | 2016-05-31 | 2017-12-07 | Danisco Us Inc. | Protease variants and uses thereof |
| EP3472313B1 (en) | 2016-06-17 | 2022-08-31 | Danisco US Inc. | Protease variants and uses thereof |
| EP3535365A2 (en) | 2016-11-07 | 2019-09-11 | Danisco US Inc. | Laundry detergent composition |
| JP2020500860A (ja) | 2016-11-23 | 2020-01-16 | ゴジョ・インダストリーズ・インコーポレイテッド | プロバイオティック/プレバイオティックな有効成分を含む消毒薬組成物 |
| EP4001389A1 (en) | 2016-12-02 | 2022-05-25 | The Procter & Gamble Company | Cleaning compositions including enzymes |
| CA3044420C (en) | 2016-12-02 | 2022-03-22 | The Procter & Gamble Company | Cleaning compositions including enzymes |
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| JP2012508031A (ja) | 2012-04-05 |
| US8753861B2 (en) | 2014-06-17 |
| CN106399280A (zh) | 2017-02-15 |
| JP6120815B2 (ja) | 2017-04-26 |
| BR122013014157A2 (pt) | 2018-11-13 |
| US9096838B2 (en) | 2015-08-04 |
| CN106399280B (zh) | 2020-12-22 |
| CN103361196A (zh) | 2013-10-23 |
| RU2560978C2 (ru) | 2015-08-20 |
| KR20110095260A (ko) | 2011-08-24 |
| CA2743302A1 (en) | 2010-05-20 |
| EP3031894A1 (en) | 2016-06-15 |
| US20150065412A1 (en) | 2015-03-05 |
| AR074311A1 (es) | 2011-01-05 |
| JP2013236632A (ja) | 2013-11-28 |
| RU2011123739A (ru) | 2012-12-20 |
| WO2010056653A3 (en) | 2010-09-16 |
| EP2362896A2 (en) | 2011-09-07 |
| US20140308736A1 (en) | 2014-10-16 |
| CN102209775A (zh) | 2011-10-05 |
| CN103122345A (zh) | 2013-05-29 |
| JP2015015952A (ja) | 2015-01-29 |
| WO2010056653A2 (en) | 2010-05-20 |
| JP5893584B2 (ja) | 2016-03-23 |
| MX2011004802A (es) | 2011-06-16 |
| EP2650354A2 (en) | 2013-10-16 |
| EP2650354A3 (en) | 2014-02-12 |
| US20160010072A1 (en) | 2016-01-14 |
| CN103361196B (zh) | 2016-01-27 |
| US20120003718A1 (en) | 2012-01-05 |
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