BRPI0922710A2 - método para a produção de plaquetas - Google Patents

método para a produção de plaquetas

Info

Publication number
BRPI0922710A2
BRPI0922710A2 BRPI0922710A BRPI0922710A BRPI0922710A2 BR PI0922710 A2 BRPI0922710 A2 BR PI0922710A2 BR PI0922710 A BRPI0922710 A BR PI0922710A BR PI0922710 A BRPI0922710 A BR PI0922710A BR PI0922710 A2 BRPI0922710 A2 BR PI0922710A2
Authority
BR
Brazil
Prior art keywords
platelets
production
Prior art date
Application number
BRPI0922710A
Other languages
English (en)
Inventor
Claire Dunois-Larde
Dominique Baruch
Elisabeth Cramer-Borde
Original Assignee
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med filed Critical Inst Nat Sante Rech Med
Publication of BRPI0922710A2 publication Critical patent/BRPI0922710A2/pt
Publication of BRPI0922710A8 publication Critical patent/BRPI0922710A8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0644Platelets; Megakaryocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/125Stem cell factor [SCF], c-kit ligand [KL]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/145Thrombopoietin [TPO]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2521/00Culture process characterised by the use of hydrostatic pressure, flow or shear forces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
BRPI0922710A 2008-12-04 2009-12-04 método para a produção de plaquetas BRPI0922710A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08305881 2008-12-04
PCT/EP2009/066401 WO2010063823A1 (en) 2008-12-04 2009-12-04 Method for producing platelets

Publications (2)

Publication Number Publication Date
BRPI0922710A2 true BRPI0922710A2 (pt) 2016-01-05
BRPI0922710A8 BRPI0922710A8 (pt) 2018-06-26

Family

ID=40756593

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0922710A BRPI0922710A8 (pt) 2008-12-04 2009-12-04 método para a produção de plaquetas

Country Status (16)

Country Link
US (1) US9012221B2 (pt)
EP (1) EP2352815B1 (pt)
JP (1) JP5863459B2 (pt)
CN (2) CN104087552A (pt)
AU (1) AU2009324042B2 (pt)
BR (1) BRPI0922710A8 (pt)
CA (1) CA2745268C (pt)
CY (1) CY1117452T1 (pt)
DK (1) DK2352815T3 (pt)
ES (1) ES2569610T3 (pt)
HR (1) HRP20160404T8 (pt)
HU (1) HUE027112T2 (pt)
PL (1) PL2352815T3 (pt)
SI (1) SI2352815T1 (pt)
SM (1) SMT201600131B (pt)
WO (1) WO2010063823A1 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2828015C (en) * 2011-03-18 2020-06-16 New York Blood Center, Inc. Megakaryocyte and platelet production from stem cells
GB201210857D0 (en) 2012-06-19 2012-08-01 Cambridge Entpr Ltd Transcription factor mediated programming towards megakaryocytes
CN114558032B (zh) 2012-12-21 2025-07-29 安斯泰来再生医药协会 由多能干细胞制备血小板的方法及其组合物
WO2014107240A1 (en) 2013-01-03 2014-07-10 Brigham And Women's Hospital, Inc. System and method for a biomimetic fluid processing
CA2930131A1 (en) * 2013-11-19 2015-05-28 Platod Fluidic device for producing platelets
JP2015181406A (ja) * 2014-03-24 2015-10-22 東レエンジニアリング株式会社 血小板産生装置および血小板産生方法
CA2944314C (en) * 2014-03-31 2023-09-19 Brigham And Women's Hospital, Inc. Systems and methods for biomimetic fluid processing
US10538738B2 (en) * 2014-05-19 2020-01-21 Eleftherios Papoutsakis Megakaryocytic particles and microparticles for cell therapy and fate modification of stem and progenitor cells
EP3294871B1 (en) 2015-05-12 2026-04-29 HemostOD SA Combination of pharmacological and microfluidic features for improved platelets production
HK1248762A1 (zh) * 2015-06-16 2018-10-19 国立大学法人京都大学 高功能性血小板的制造方法
JP6859351B2 (ja) * 2015-09-08 2021-04-14 ブリガム・アンド・ウイミンズ・ホスピタル・インコーポレイテッド 血小板を産生するためのシステムおよび方法
CA2998463A1 (en) 2015-09-15 2017-03-23 Megakaryon Corporation Method for manufacturing platelets by rotary stirring culture method
AU2016338030A1 (en) * 2015-10-14 2018-04-26 Megakaryon Corporation Method for producing purified platelets
DK3372674T3 (da) * 2015-11-02 2020-10-12 Megakaryon Corp Fremgangsmåde til fremstilling af blodplader under anvendelse af røreindretning med frem- og tilbagegående rørebevægelse
WO2018237061A1 (en) * 2017-06-20 2018-12-27 Northwestern University Microfluidic platelet bioreactor device and systems
MX2020007071A (es) 2018-01-05 2020-11-11 Platelet Biogenesis Inc Composiciones y metodos para producir megacariocitos.
EP3813853A4 (en) 2018-06-29 2022-04-06 Platelet Biogenesis, Inc. DELIVERY COMPOSITIONS AND METHODS OF USE
BR112021000996A2 (pt) 2018-07-19 2021-04-20 Platelet Biogenesis, Inc. biorreator de recirculação empilhado
FR3101885B1 (fr) * 2019-10-11 2024-11-08 Francais Du Sang Ets Systeme pour la liberation de plaquettes et procede de liberation de plaquettes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4344560A (en) * 1979-11-02 1982-08-17 Asahi Kasei Kogyo Kabushiki Kaisha Container, apparatus and method for separating platelets
DE19956156A1 (de) * 1999-11-23 2001-06-13 Univ Eberhard Karls Verfahren zur Aufbereitung eines Präparates von Thrombozyten und Thrombozytenpräparat
EP1369128A1 (en) * 2002-06-07 2003-12-10 Procorde GmbH Inhibitors of glycoprotein VI and their therapeutic use
AU2005302258B2 (en) * 2004-11-01 2010-10-21 Wisconsin Alumni Research Foundation Platelets from stem cells
CA2593328C (en) * 2005-01-14 2018-02-06 Ablynx N.V. Methods and assays for distinguishing between different forms of diseases and disorders characterized by thrombocytopenia and/or by spontaneous interaction between von willebrand factor (vwf) and platelets
JP5419076B2 (ja) * 2008-05-15 2014-02-19 旭化成メディカル株式会社 血小板の誘導方法

Also Published As

Publication number Publication date
EP2352815B1 (en) 2016-02-10
SMT201600131B (it) 2016-07-01
JP5863459B2 (ja) 2016-02-16
SI2352815T1 (sl) 2016-10-28
DK2352815T3 (en) 2016-05-17
BRPI0922710A8 (pt) 2018-06-26
JP2012510804A (ja) 2012-05-17
WO2010063823A1 (en) 2010-06-10
CN104087552A (zh) 2014-10-08
US9012221B2 (en) 2015-04-21
HUE027112T2 (en) 2016-08-29
PL2352815T3 (pl) 2016-07-29
CA2745268C (en) 2018-11-13
US20120014933A1 (en) 2012-01-19
CN102300984A (zh) 2011-12-28
CN102300984B (zh) 2014-06-04
CA2745268A1 (en) 2010-06-10
CY1117452T1 (el) 2017-04-26
AU2009324042A1 (en) 2011-07-07
HRP20160404T8 (hr) 2016-07-01
AU2009324042B2 (en) 2014-12-04
EP2352815A1 (en) 2011-08-10
HRP20160404T1 (hr) 2016-06-17
ES2569610T3 (es) 2016-05-11
HK1165491A1 (en) 2012-10-05

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law
B07E Notice of approval relating to section 229 industrial property law
B06U Preliminary requirement: requests with searches performed by other patent offices: suspension of the patent application procedure
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements