BRPI0923165A8 - método para a produção de uma solução contendo polissacarídeos capsulares de streptococcus pneumoniae isolados de alto peso molecular, bem como solução contendo os referidos polissacarídeos - Google Patents

método para a produção de uma solução contendo polissacarídeos capsulares de streptococcus pneumoniae isolados de alto peso molecular, bem como solução contendo os referidos polissacarídeos

Info

Publication number
BRPI0923165A8
BRPI0923165A8 BRPI0923165A BRPI0923165A BRPI0923165A8 BR PI0923165 A8 BRPI0923165 A8 BR PI0923165A8 BR PI0923165 A BRPI0923165 A BR PI0923165A BR PI0923165 A BRPI0923165 A BR PI0923165A BR PI0923165 A8 BRPI0923165 A8 BR PI0923165A8
Authority
BR
Brazil
Prior art keywords
solution containing
polysaccharides
producing
molecular weight
well
Prior art date
Application number
BRPI0923165A
Other languages
English (en)
Inventor
Heather Crinean Jean
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of BRPI0923165A2 publication Critical patent/BRPI0923165A2/pt
Publication of BRPI0923165A8 publication Critical patent/BRPI0923165A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00—Applications
    • C08L2203/02—Applications for biomedical use

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
BRPI0923165A 2008-12-18 2009-12-17 método para a produção de uma solução contendo polissacarídeos capsulares de streptococcus pneumoniae isolados de alto peso molecular, bem como solução contendo os referidos polissacarídeos BRPI0923165A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13857008P 2008-12-18 2008-12-18
PCT/US2009/068424 WO2010080484A1 (en) 2008-12-18 2009-12-17 Method for controlling streptococcus pneumoniae polysaccharide molecular weight using carbon

Publications (2)

Publication Number Publication Date
BRPI0923165A2 BRPI0923165A2 (pt) 2016-02-10
BRPI0923165A8 true BRPI0923165A8 (pt) 2017-09-12

Family

ID=41666441

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0923165A BRPI0923165A8 (pt) 2008-12-18 2009-12-17 método para a produção de uma solução contendo polissacarídeos capsulares de streptococcus pneumoniae isolados de alto peso molecular, bem como solução contendo os referidos polissacarídeos

Country Status (18)

Country Link
US (4) US20100160622A1 (pt)
EP (1) EP2385981B1 (pt)
JP (2) JP5789514B2 (pt)
KR (1) KR101307703B1 (pt)
CN (1) CN102257127B (pt)
AU (1) AU2009335824B2 (pt)
BR (1) BRPI0923165A8 (pt)
CA (1) CA2743708C (pt)
DK (1) DK2385981T3 (pt)
ES (1) ES2749952T3 (pt)
HU (1) HUE046859T2 (pt)
IL (1) IL213215A (pt)
MX (1) MX346071B (pt)
PL (1) PL2385981T3 (pt)
PT (1) PT2385981T (pt)
RU (1) RU2524436C2 (pt)
SI (1) SI2385981T1 (pt)
WO (1) WO2010080484A1 (pt)

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KR101515078B1 (ko) 2005-12-22 2015-04-24 글락소스미스클라인 바이오로지칼즈 에스.에이. 백신
BRPI0922981A8 (pt) * 2008-12-18 2019-11-26 Wyeth Llc método para o controle do peso molecular polissacarídeo para o sorotipo 19a de streptococcus pneumoniae
US20120052088A1 (en) 2009-04-30 2012-03-01 Coley Pharmaceutical Group, Inc. Pneumococcal vaccine and uses thereof
WO2011151841A1 (en) * 2010-05-31 2011-12-08 Panacea Biotec Limited Fermentation process for streptococcus pneumoniae
US11951165B2 (en) 2016-12-30 2024-04-09 Vaxcyte, Inc. Conjugated vaccine carrier proteins
CN110366428B (zh) 2016-12-30 2024-05-17 Vaxcyte公司 具有非天然氨基酸的多肽-抗原缀合物
EP4656208A3 (en) 2017-01-31 2026-03-04 Merck Sharp & Dohme LLC Methods for making polysaccharide-protein conjugates
JP7680185B2 (ja) 2017-02-24 2025-05-20 メルク・シャープ・アンド・ドーム・エルエルシー 肺炎連鎖球菌多糖－タンパク質コンジュゲートの免疫原性の増強
MX394768B (es) 2017-09-07 2025-03-21 Merck Sharp & Dohme Llc Polisacaridos neumococicos y su uso en conjugados de polisacarido inmunogenico con proteina.
MX394767B (es) 2017-09-07 2025-03-24 Merck Sharp & Dohme Llc Polisacaridos neumococicos y su uso en conjugados de polisacarido inmunogenico con proteina transportadora.
CN107746825A (zh) * 2017-11-30 2018-03-02 成都欧林生物科技股份有限公司 利于肺炎链球菌快速增殖的培养基
CN108004160A (zh) * 2017-11-30 2018-05-08 成都欧林生物科技股份有限公司 含有中药材的菌种培养基的制备方法
ES3058336T3 (es) 2017-12-06 2026-03-10 Merck Sharp & Dohme Llc Composiciones que comprenden conjugados polisacárido-proteína de Streptococcus pneumoniae y métodos de uso de los mismos
EP3787673A4 (en) 2018-04-30 2022-04-27 Merck Sharp & Dohme Corp. Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates
EP3788143B1 (en) 2018-04-30 2023-06-28 Merck Sharp & Dohme LLC Methods for providing a homogenous solution of lyophilized mutant diptheria toxin in dimethylsulfoxide
US12144855B2 (en) 2018-04-30 2024-11-19 Merck Sharp & Dohme Llc Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates from lyospheres
CN112969474A (zh) 2018-09-12 2021-06-15 艾芬尼维克斯公司 多价肺炎球菌疫苗
CN113423815A (zh) * 2018-12-06 2021-09-21 创赏有限公司 非动物来源培养基上的细菌生长
CR20210333A (es) 2018-12-19 2021-08-18 Merck Sharp & Dohme Composiciones que comprenden conjugados de polisacárido de streptococcus pneumoniae con proteína y sus métodos de uso

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CA1115210A (en) 1977-11-28 1981-12-29 Dennis J. Carlo Pneumococcal vaccine
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US4242501A (en) 1979-08-08 1980-12-30 American Cyanamid Company Purification of pneumococcal capsular polysaccharides
FR2495939B1 (fr) 1980-12-11 1985-10-11 Merieux Inst Procede de purification de polyosides de streptococcus pneumoniae et vaccin a base de polyosides ainsi purifies
BE889979A (fr) 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation
US4686102A (en) * 1984-04-12 1987-08-11 American Cyanamid Company Multivalent pneumococcal vaccine and preparation thereof
CA2059692C (en) * 1991-01-28 2004-11-16 Peter J. Kniskern Pneumoccoccal polysaccharide conjugate vaccine
CA2059693C (en) * 1991-01-28 2003-08-19 Peter J. Kniskern Polysaccharide antigens from streptococcus pneumoniae
US5714354A (en) * 1995-06-06 1998-02-03 American Home Products Corporation Alcohol-free pneumococcal polysaccharide purification process
US5656206A (en) * 1995-06-14 1997-08-12 Transitions Optical, Inc. Substituted naphthopyrans
US6146902A (en) 1998-12-29 2000-11-14 Aventis Pasteur, Inc. Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions
AU2001245795B2 (en) 2000-03-16 2005-07-28 The Children's Hospital Of Philadelphia Modulating production of pneumococcal capsular polysaccharide
US6743610B2 (en) * 2001-03-30 2004-06-01 The University Of Chicago Method to produce succinic acid from raw hydrolysates
US7741092B2 (en) * 2002-10-31 2010-06-22 Verenium Corporation Amylases, nucleic acids encoding them and methods for making and using them
US7320874B2 (en) * 2003-07-08 2008-01-22 Aventis Pasteur Sa Assaying the teichoic acids of gram+ bacteria
DE602004025951D1 (de) * 2003-09-11 2010-04-22 Staat Der Nederlanden Vert Doo Verfahren zur herstellung eines kapselpolysaccharids zur verwendung in konjugat-impfstoffen
US20070184072A1 (en) 2005-04-08 2007-08-09 Wyeth Multivalent pneumococcal polysaccharide-protein conjugate composition
CN101155833B (zh) 2005-04-08 2011-04-20 惠氏公司 通过pH操作将污染物与肺炎链球菌多糖分离
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EP3311836A1 (en) * 2005-04-08 2018-04-25 Wyeth LLC Multivalent pneumococcal polysaccharide-protein conjugate composition
US7709001B2 (en) * 2005-04-08 2010-05-04 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
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DK2074221T3 (da) 2006-10-10 2010-09-06 Wyeth Llc Forbedrede fremgangsmåder til separation af streptococcus pneumoniae type 3 polysakkarider
CN101663327B (zh) * 2007-03-23 2014-05-07 惠氏公司 产生肺炎链球菌(streptococcus pneumoniae)荚膜多糖的缩短的纯化方法
CA2690708A1 (en) * 2007-06-26 2008-12-31 Glaxosmithkline Biologicals S.A. Vaccine
BRPI0922981A8 (pt) * 2008-12-18 2019-11-26 Wyeth Llc método para o controle do peso molecular polissacarídeo para o sorotipo 19a de streptococcus pneumoniae

Also Published As

Publication number Publication date
CN102257127A (zh) 2011-11-23
RU2011124143A (ru) 2013-01-27
HUE046859T2 (hu) 2020-03-30
AU2009335824B2 (en) 2013-07-04
MX346071B (es) 2017-03-02
PL2385981T3 (pl) 2020-01-31
IL213215A (en) 2017-08-31
US20100160622A1 (en) 2010-06-24
WO2010080484A1 (en) 2010-07-15
JP2015144614A (ja) 2015-08-13
JP6095715B2 (ja) 2017-03-15
US20170224802A1 (en) 2017-08-10
DK2385981T3 (da) 2019-10-21
ES2749952T3 (es) 2020-03-24
EP2385981B1 (en) 2019-09-04
SI2385981T1 (sl) 2019-11-29
EP2385981A1 (en) 2011-11-16
CA2743708C (en) 2018-01-09
RU2524436C2 (ru) 2014-07-27
PT2385981T (pt) 2019-10-28
KR20110091548A (ko) 2011-08-11
IL213215A0 (en) 2011-07-31
US11376315B2 (en) 2022-07-05
JP2012512659A (ja) 2012-06-07
AU2009335824A1 (en) 2010-07-15
JP5789514B2 (ja) 2015-10-07
KR101307703B1 (ko) 2013-09-11
US20200323974A1 (en) 2020-10-15
US20150376667A1 (en) 2015-12-31
HK1163737A1 (en) 2012-09-14
CN102257127B (zh) 2014-01-01
MX2011006431A (es) 2011-07-19
BRPI0923165A2 (pt) 2016-02-10
CA2743708A1 (en) 2010-07-15

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B25G Requested change of headquarter approved

Owner name: WYETH LLC (US)