BRPI0923433A2 - Síntese de compostos fucosilados - Google Patents

Síntese de compostos fucosilados

Info

Publication number
BRPI0923433A2
BRPI0923433A2 BRPI0923433-0A BRPI0923433A BRPI0923433A2 BR PI0923433 A2 BRPI0923433 A2 BR PI0923433A2 BR PI0923433 A BRPI0923433 A BR PI0923433A BR PI0923433 A2 BRPI0923433 A2 BR PI0923433A2
Authority
BR
Brazil
Prior art keywords
synthesis
fucosylated compounds
fucosylated
compounds
Prior art date
Application number
BRPI0923433-0A
Other languages
English (en)
Inventor
Eric Hüfner
Julia Parkot
Stefan Jennewein
Original Assignee
Jennewein Biotechnologie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40550215&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0923433(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Jennewein Biotechnologie Gmbh filed Critical Jennewein Biotechnologie Gmbh
Publication of BRPI0923433A2 publication Critical patent/BRPI0923433A2/pt
Publication of BRPI0923433B1 publication Critical patent/BRPI0923433B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
BRPI0923433-0A 2008-12-19 2009-12-18 Método para produzir uma célula geneticamente modificada tendo a capacidade de produzir compostos fucosilados e método para fazer um composto fucosilado BRPI0923433B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08172267 2008-12-19
EP08172267.0 2008-12-19
PCT/EP2009/067531 WO2010070104A1 (en) 2008-12-19 2009-12-18 Synthesis of fucosylated compounds

Publications (2)

Publication Number Publication Date
BRPI0923433A2 true BRPI0923433A2 (pt) 2015-08-11
BRPI0923433B1 BRPI0923433B1 (pt) 2021-06-01

Family

ID=40550215

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0923433-0A BRPI0923433B1 (pt) 2008-12-19 2009-12-18 Método para produzir uma célula geneticamente modificada tendo a capacidade de produzir compostos fucosilados e método para fazer um composto fucosilado

Country Status (14)

Country Link
US (2) US20110300584A1 (pt)
EP (1) EP2379708B1 (pt)
JP (1) JP5726751B2 (pt)
CN (1) CN102257128A (pt)
AU (1) AU2009329543B2 (pt)
BR (1) BRPI0923433B1 (pt)
CO (1) CO6362044A2 (pt)
IN (1) IN2011MU01050A (pt)
MX (1) MX2011006371A (pt)
MY (1) MY183602A (pt)
NZ (1) NZ593448A (pt)
RU (1) RU2584599C2 (pt)
SG (1) SG171814A1 (pt)
WO (1) WO2010070104A1 (pt)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG176651A1 (en) 2009-06-08 2012-01-30 Jennewein Biotechnologie Gmbh Hmo synthesis
AU2015215937B2 (en) * 2010-07-12 2017-03-16 Inbiose N.V. Metabolically engineered organisms for the production of added value bio-products
EP2439264B1 (en) * 2010-10-11 2015-06-03 Jennewein Biotechnologie GmbH Novel fucosyltransferases and their applications
CN102120999A (zh) * 2010-12-17 2011-07-13 天津科技大学 利用基因工程菌株耦合发酵合成人乳岩藻糖基化寡糖的方法
ES2804258T3 (es) 2010-12-31 2021-02-05 Abbott Lab Procedimientos para reducir la incidencia de estrés oxidativo usando oligosacáridos de leche humana, vitamina C y agentes antiinflamatorios
MY191538A (en) 2010-12-31 2022-06-30 Abbott Lab Human milk oligosaccharides to promote growth of beneficial bacteria
CA2822490C (en) 2010-12-31 2020-03-31 Abbott Laboratories Nutritional compositions comprising human milk oligosaccharides and nucleotides and uses thereof for treating and/or preventing enteric viral infection
ES2667393T3 (es) 2010-12-31 2018-05-10 Abbott Laboratories Oligosacáridos de leche humana para modular inflamación
MY166945A (en) 2010-12-31 2018-07-25 Abbott Lab Nutritional formulations including human milk oligosaccharides and long chain polyunsaturated polyunsaturated fatty acids and uses thereof
US8802650B2 (en) 2010-12-31 2014-08-12 Abbott Laboratories Methods of using human milk oligosaccharides for improving airway respiratory health
CN107019701B (zh) 2010-12-31 2020-07-28 雅培制药有限公司 使用人乳低聚糖来降低婴儿、幼儿或儿童的坏死性小肠结肠炎的发病率的方法
ES2439507T3 (es) * 2011-01-20 2014-01-23 Jennewein Biotechnologie Gmbh Fucosiltransferasas novedosas y sus aplicaciones
AU2012217650B9 (en) 2011-02-16 2017-09-14 Glycosyn LLC Biosynthesis of human milk oligosaccharides in engineered bacteria
JP5881035B2 (ja) * 2011-03-17 2016-03-09 国立研究開発法人産業技術総合研究所 酵母を用いた糖ヌクレオチドの合成法
JP2014509864A (ja) 2011-03-23 2014-04-24 グリコド Gdp−フコースを産生可能な酵母組換え細胞
NL2007268C2 (en) 2011-08-16 2013-02-19 Friesland Brands Bv Nutritional compositions comprising human milk oligosaccharides and uses thereof.
CA2846603A1 (en) 2011-08-29 2013-03-07 Abbott Laboratories Human milk oligosaccharides for preventing injury and/or promoting healing of the gastrointestinal tract
AU2012351501B2 (en) * 2011-12-16 2018-06-14 Inbiose N.V. Mutant microorganisms to synthesize colanic acid, mannosylated and/or fucosylated oligosaccharides
US9029136B2 (en) 2012-07-25 2015-05-12 Glycosyn LLC Alpha (1,2) fucosyltransferases suitable for use in the production of fucosylated oligosaccharides
WO2014048439A1 (en) 2012-09-25 2014-04-03 Glycom A/S Glycoconjugate synthesis
EP2728009B1 (en) 2012-10-31 2017-07-26 Jennewein Biotechnologie GmbH Process for producing monosaccharides
US9834574B2 (en) 2012-11-13 2017-12-05 Glycom A/S Crystalline 3-O-fucosyllactose
WO2014086373A1 (en) 2012-12-07 2014-06-12 Glycom A/S Crystallisation of human milk oligosaccharides (hmo)
WO2015032413A1 (en) * 2013-09-06 2015-03-12 Glycom A/S Fermentative production of oligosaccharides
US9902984B2 (en) 2013-09-06 2018-02-27 Glycom A/S Fermentative production of oligosaccharides
ES2875327T3 (es) 2013-09-10 2021-11-10 Chr Hansen Hmo Gmbh Producción de oligosacáridos
ES2701163T3 (es) 2014-01-20 2019-02-21 Jennewein Biotechnologie Gmbh Procedimiento para la purificación eficiente de oligosacáridos de la leche humana (HMO) neutros a partir de la fermentación microbiana
DE202015009782U1 (de) 2014-06-11 2020-02-10 Glycom A/S Trennung von 2'-O-Fucosyllactose aus Fermentationsbrühe
US11926858B2 (en) 2014-06-27 2024-03-12 Glycom A/S Oligosaccharide production
CN113684233B (zh) 2014-06-27 2024-11-29 格礼卡姆股份公司 寡糖的制备
US20170204443A1 (en) * 2014-07-14 2017-07-20 Basf Se Biotechnological production of lnt, lnnt and the fucosylated derivatives thereof
US10676770B2 (en) 2014-12-16 2020-06-09 Glycom A/S Separation of 2′-FL from a fermentation broth
WO2017101958A1 (en) 2015-12-18 2017-06-22 Glycom A/S Fermentative production of oligosaccharides
EP3506768B8 (en) 2016-08-31 2026-02-25 OligoScience Biotechnology GmbH Milk replacer composition comprising 2'-fucosyllactose for use in the treatment or prevention of gastro-intestinal diseases of production animals
EP3315610B1 (en) * 2016-10-29 2020-12-16 Jennewein Biotechnologie GmbH Process for the production of fucosylated oligosaccharides
US11214588B2 (en) 2017-06-30 2022-01-04 Glycom A/S Synthesis of oligosaccharides
EP3425052A1 (en) 2017-07-07 2019-01-09 Jennewein Biotechnologie GmbH Fucosyltransferases and their use in producing fucosylated oligosaccharides
CN119655445A (zh) 2017-07-12 2025-03-21 格礼卡姆股份公司 包含中性单糖或寡糖和酸性非碳水化合物组分的无定形混合物
CA3076920A1 (en) 2017-10-04 2019-04-11 The Regents Of The University Of California Immunomodulatory oligosaccharides
EP3486326A1 (en) 2017-11-21 2019-05-22 Jennewein Biotechnologie GmbH Method for the purification of n-acetylneuraminic acid from a fermentation broth
ES3040419T3 (en) 2017-12-08 2025-10-30 Chr Hansen Hmo Gmbh Spray-dried lacto-n-fucopentaose
EP3494807A1 (en) 2017-12-11 2019-06-12 Jennewein Biotechnologie GmbH Spray-dried sialyllactose
PL3494805T3 (pl) 2017-12-08 2025-10-06 Chr. Hansen HMO GmbH Suszone rozpyłowo tetrasacharydy
ES3039971T3 (en) 2017-12-08 2025-10-28 Chr Hansen Hmo Gmbh Spray-dried 3-fucosyllactose
AU2018380962B2 (en) 2017-12-08 2024-12-19 Chr. Hansen HMO GmbH Spray-dried lacto-N-fucopentaose
ES3026362T3 (en) 2018-02-08 2025-06-11 Chr Hansen Hmo Gmbh Spray-dried mixture of human milk oligosaccharides
EP3867258A1 (en) 2018-10-18 2021-08-25 Basf Se Method for obtaining crystalline 2'-fucosyllactose
CN113195730A (zh) 2018-12-19 2021-07-30 巴斯夫欧洲公司 从包含生物质和至少一种寡糖的溶液中分离生物质的方法
WO2021019104A2 (en) 2019-09-18 2021-02-04 Basf Se A production host for producing human milk oligosaccharides
CN110672756B (zh) * 2019-11-07 2020-12-29 江南大学 一种奶粉中2’-岩藻糖基乳糖含量的检测方法
WO2021094133A2 (en) 2019-11-13 2021-05-20 Basf Se Enzymatic hydrolysis of 2',3-difucosyllactose
WO2021122687A1 (en) 2019-12-19 2021-06-24 Basf Se Increasing space-time-yield, carbon-conversion-efficiency and carbon substrate flexibility in the production of fine chemicals
EP3848471A1 (en) 2020-01-10 2021-07-14 Chr. Hansen HMO GmbH Sequential fermentative production of oligosaccharides
KR20220154158A (ko) 2020-03-12 2022-11-21 글리콤 에이/에스 2'-fl의 결정화
EP3922727A1 (en) 2020-06-12 2021-12-15 Basf Se Method for separating biomass from a solution comprising biomass and at least one aroma compound
KR20230022867A (ko) 2020-06-12 2023-02-16 바스프 에스이 발효 브로스의 개선된 탈염 및 올리고당과 같은 정밀 화학물질의 정제
EP4179102A1 (en) 2020-07-13 2023-05-17 Glycom A/S Oligosaccharide production
EP4341277A1 (en) 2021-05-17 2024-03-27 DSM IP Assets B.V. Microbial strain expressing an invertase/sucrose hydrolase
PH12023553158A1 (en) 2021-05-20 2024-03-11 Chr Hansen As Sequential fermentative production of oligosaccharides
AU2023331862A1 (en) 2022-08-29 2025-02-13 Chr. Hansen A/S Process for the production of a purified human milk oligosaccharide derived from a microbial fermentation process

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2125092C1 (ru) * 1991-10-15 1999-01-20 Дзе Скриппс Рисерч Инститьют Способ получения фукозилированного углевода, способ получения фукозилированной сиалилированной углеводной молекулы, реакционная система in vitro
US6238894B1 (en) 1998-11-04 2001-05-29 Diane Taylor α1,2 fucosyltransferase
EP1131415A4 (en) 1998-11-18 2002-09-11 Neose Technologies Inc PRODUCTION OF CHEAP OLIGOSACCHARIDES
US20040058418A1 (en) * 2000-04-11 2004-03-25 Tetsuo Endo Alpha 1,2-fucosyltransferase and process for producing fucose-containing complex carbohydrate
ATE440959T1 (de) 2000-06-28 2009-09-15 Glycofi Inc Verfahren für die herstellung modifizierter glykoproteine
US20020132320A1 (en) 2001-01-10 2002-09-19 Wang Peng George Glycoconjugate synthesis using a pathway-engineered organism
WO2003018794A1 (fr) * 2001-08-24 2003-03-06 Kyowa Hakko Kogyo Co., Ltd. $g(a)-1,2-fucosyle transferase et adn codant pour celle-ci
FR2840920B1 (fr) * 2002-06-18 2006-06-23 Biochimie Appliquee Soc Nouveau microorganisme de la famille des enterobacteriaceae
EP2497478A3 (en) * 2003-12-05 2012-11-07 Children's Hospital Medical Center Oligosaccaride compositions and use thereof in the treatment of infection
US7326770B2 (en) * 2004-01-22 2008-02-05 Neose Technologies, Inc. H. pylori fucosyltransferases
US20080145899A1 (en) * 2004-09-17 2008-06-19 Neose Technologies Inc Production of Oligosaccharides By Microorganisms
WO2006135075A1 (en) * 2005-06-17 2006-12-21 Ajinomoto Co., Inc. A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family with enhanced expression of the fucpikur operon
AU2007222375B2 (en) * 2006-03-09 2012-12-20 Centre National De La Recherche Scientifique (Cnrs) Method of producing sialylated oligosaccharides
US20070221747A1 (en) 2006-03-22 2007-09-27 Siemens Vdo Automotive Corporation Super imposed signal for an actuator and heater of a fuel injector
CA2679732A1 (en) * 2007-03-07 2008-09-18 Glycofi, Inc. Production of glycoproteins with modified fucosylation

Also Published As

Publication number Publication date
MY183602A (en) 2021-03-02
IN2011MU01050A (pt) 2011-12-30
MX325472B (pt) 2014-11-20
HK1159173A1 (zh) 2012-07-27
CN102257128A (zh) 2011-11-23
EP2379708A1 (en) 2011-10-26
CO6362044A2 (es) 2012-01-20
AU2009329543B2 (en) 2015-04-16
SG171814A1 (en) 2011-07-28
RU2584599C2 (ru) 2016-05-20
US20190382737A1 (en) 2019-12-19
JP2012512643A (ja) 2012-06-07
RU2011129780A (ru) 2013-01-27
NZ593448A (en) 2012-06-29
WO2010070104A1 (en) 2010-06-24
AU2009329543A1 (en) 2010-06-24
EP2379708B1 (en) 2016-04-27
US11390855B2 (en) 2022-07-19
BRPI0923433B1 (pt) 2021-06-01
JP5726751B2 (ja) 2015-06-03
MX2011006371A (es) 2011-09-27
US20110300584A1 (en) 2011-12-08

Similar Documents

Publication Publication Date Title
EP2510089A4 (en) SYNTHESIS OF PRAZOL COMPOUNDS
EP2289050A4 (en) SHADER INTERFACES
DK2288375T3 (da) Pegylerede insulin-lispro-forbindelser
BRPI0920707A2 (pt) compostos
DK2242759T3 (da) Forbindelser
BRPI1013614A2 (pt) compostos substituídos de espiro-amida
DK2427449T3 (da) Vinylindazolylforbindelser
BR112012006859A2 (pt) compostos
EP2350110A4 (en) NEW STEVIOLGLYKOSIDE
EP2443946A4 (en) SPARE CIGARETTE
PT2260053E (pt) Análogos de oxitocina
BRPI1005525A2 (pt) compostos de azaazuleno
SMT201600045B (it) Composti tetraciclinici c7-fluoro sostituiti
UA18712S (uk) Шоколад
BRPI0820677A2 (pt) Misturas de compostos pesticidas
DK2297162T3 (da) Forbindelser
EP2349335A4 (en) LEVETIRACETAM IMMUNOASSAYS
ZA201100123B (en) Bromine-facilitated synthesis of fluoro-sulfur compounds
BRPI0916432A2 (pt) compostos
BRPI0911393A2 (pt) composto de 5-hidroxipirimidina-4-carboxamida
CU23884B1 (es) Derivados de dibenzotiazepina
DK2206698T3 (da) Ethynylindolforbindelser
BRPI0821567A2 (pt) Misturas de compostos pesticidas
BRPI0820650A2 (pt) Misturas de compostos pesticidas
FR2928356B1 (fr) Distributeur de comprimes

Legal Events

Date Code Title Description
B15K Others concerning applications: alteration of classification

Ipc: C12N 9/12 (2006.01), A23L 33/00 (2016.01), C12N 9/

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B09W Correction of the decision to grant [chapter 9.1.4 patent gazette]

Free format text: RETIFICACAO DA PUBLICACAO DEVIDO A I NCORRECOES NO QUADRO 1 DO PARECER DE DEFERIMENTO.

B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 18/12/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B25D Requested change of name of applicant approved

Owner name: CHR. HANSEN HMO GMBH (DE)