BRPI0923433A2 - Síntese de compostos fucosilados - Google Patents

Síntese de compostos fucosilados

Info

Publication number
BRPI0923433A2
BRPI0923433A2 BRPI0923433-0A BRPI0923433A BRPI0923433A2 BR PI0923433 A2 BRPI0923433 A2 BR PI0923433A2 BR PI0923433 A BRPI0923433 A BR PI0923433A BR PI0923433 A2 BRPI0923433 A2 BR PI0923433A2
Authority
BR
Brazil
Prior art keywords
synthesis
fucosylated compounds
fucosylated
compounds
Prior art date
Application number
BRPI0923433-0A
Other languages
English (en)
Inventor
Eric Hüfner
Julia Parkot
Stefan Jennewein
Original Assignee
Jennewein Biotechnologie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40550215&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0923433(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Jennewein Biotechnologie Gmbh filed Critical Jennewein Biotechnologie Gmbh
Publication of BRPI0923433A2 publication Critical patent/BRPI0923433A2/pt
Publication of BRPI0923433B1 publication Critical patent/BRPI0923433B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
BRPI0923433-0A 2008-12-19 2009-12-18 Método para produzir uma célula geneticamente modificada tendo a capacidade de produzir compostos fucosilados e método para fazer um composto fucosilado BRPI0923433B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08172267.0 2008-12-19
EP08172267 2008-12-19
PCT/EP2009/067531 WO2010070104A1 (en) 2008-12-19 2009-12-18 Synthesis of fucosylated compounds

Publications (2)

Publication Number Publication Date
BRPI0923433A2 true BRPI0923433A2 (pt) 2015-08-11
BRPI0923433B1 BRPI0923433B1 (pt) 2021-06-01

Family

ID=40550215

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0923433-0A BRPI0923433B1 (pt) 2008-12-19 2009-12-18 Método para produzir uma célula geneticamente modificada tendo a capacidade de produzir compostos fucosilados e método para fazer um composto fucosilado

Country Status (14)

Country Link
US (2) US20110300584A1 (pt)
EP (1) EP2379708B1 (pt)
JP (1) JP5726751B2 (pt)
CN (1) CN102257128A (pt)
AU (1) AU2009329543B2 (pt)
BR (1) BRPI0923433B1 (pt)
CO (1) CO6362044A2 (pt)
IN (1) IN2011MU01050A (pt)
MX (1) MX2011006371A (pt)
MY (1) MY183602A (pt)
NZ (1) NZ593448A (pt)
RU (1) RU2584599C2 (pt)
SG (1) SG171814A1 (pt)
WO (1) WO2010070104A1 (pt)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2440661T3 (en) 2009-06-08 2018-03-12 Jennewein Biotechnologie Gmbh HMO synthesis
AU2015215937B2 (en) * 2010-07-12 2017-03-16 Inbiose N.V. Metabolically engineered organisms for the production of added value bio-products
EP2944690B1 (en) * 2010-10-11 2017-12-20 Jennewein Biotechnologie GmbH Novel fucosyltransferases and their applications
CN102120999A (zh) * 2010-12-17 2011-07-13 天津科技大学 利用基因工程菌株耦合发酵合成人乳岩藻糖基化寡糖的方法
MY196432A (en) * 2010-12-31 2023-04-10 Abbott Lab Methods Of Using Human Milk Oligosaccharides For Improving Airway Respiratory Health
DK2658399T4 (da) 2010-12-31 2024-03-25 Abbott Lab Ernæringssammensætninger omfattende humane mælkeoligosaccharider til anvendelse i behandling og/eller forebyggelse af enterisk rotavirus-infektion
BR112013016606A2 (pt) 2010-12-31 2016-09-27 Abbott Lab processos para redução de incidência de tensão oxidante usando oligossacarídeos de leite humano, vitamina c e agentes antiflamatórios
CA2822219C (en) 2010-12-31 2020-12-29 Abbott Laboratories Methods for decreasing the incidence of necrotizing enterocolitis in infants, toddlers, or children using human milk oligosaccharides
MY191538A (en) 2010-12-31 2022-06-30 Abbott Lab Human milk oligosaccharides to promote growth of beneficial bacteria
BR112013016903A2 (pt) 2010-12-31 2019-09-24 Abbott Lab oligossacarídeos de leite humano para modular inflamação
BR112013016587A2 (pt) 2010-12-31 2016-09-27 Abbott Lab formulações nutricionais incluindo oligossacarídeos de leite humano e antioxidantes e usos das mesmas
EP2479263B1 (en) * 2011-01-20 2013-11-27 Jennewein Biotechnologie GmbH Novel Fucosyltransferases and their applications
DE12746649T1 (de) * 2011-02-16 2016-09-29 Glycosyn LLC Biosynthese menschlicher milcholigosaccaride in manipulierten Bakterien
JP5881035B2 (ja) * 2011-03-17 2016-03-09 国立研究開発法人産業技術総合研究所 酵母を用いた糖ヌクレオチドの合成法
JP2014509864A (ja) 2011-03-23 2014-04-24 グリコド Gdp−フコースを産生可能な酵母組換え細胞
NL2007268C2 (en) 2011-08-16 2013-02-19 Friesland Brands Bv Nutritional compositions comprising human milk oligosaccharides and uses thereof.
HK1199607A1 (en) 2011-08-29 2015-07-10 Abbott Laboratories Human milk oligosaccharides for preventing injury and/or promoting healing of the gastrointestinal tract
EP3517631B9 (en) * 2011-12-16 2023-10-04 Inbiose N.V. Mutant microorganisms to synthesize ph sensitive molecules and organic acids
US9029136B2 (en) * 2012-07-25 2015-05-12 Glycosyn LLC Alpha (1,2) fucosyltransferases suitable for use in the production of fucosylated oligosaccharides
WO2014048439A1 (en) 2012-09-25 2014-04-03 Glycom A/S Glycoconjugate synthesis
EP2728009B1 (en) * 2012-10-31 2017-07-26 Jennewein Biotechnologie GmbH Process for producing monosaccharides
EP2943500B1 (en) * 2012-11-13 2017-11-08 Glycom A/S Crystalline 3-o-fucosyllactose
WO2014086373A1 (en) 2012-12-07 2014-06-12 Glycom A/S Crystallisation of human milk oligosaccharides (hmo)
WO2015032413A1 (en) * 2013-09-06 2015-03-12 Glycom A/S Fermentative production of oligosaccharides
DK3041946T4 (en) 2013-09-06 2025-11-03 Glycom As Fermentative production of oligosaccharides
PL2845905T3 (pl) 2013-09-10 2021-09-27 Chr. Hansen HMO GmbH Wytwarzanie oligosacharydów
EP2896628B1 (en) 2014-01-20 2018-09-19 Jennewein Biotechnologie GmbH Process for efficient purification of neutral human milk oligosaccharides (HMOs) from microbial fermentation
WO2015188834A1 (en) 2014-06-11 2015-12-17 Glycom A/S Separation of 2'-o-fucosyllactose from fermentation broth
ES3002778T3 (en) 2014-06-27 2025-03-07 Glycom As Oligosaccharide production
US11926858B2 (en) 2014-06-27 2024-03-12 Glycom A/S Oligosaccharide production
AU2015291487A1 (en) * 2014-07-14 2017-02-16 Basf Se Biotechnological production of LNT, LNnT and the fucosylated derivatives thereof
DK3233875T3 (en) 2014-12-16 2022-12-19 Glycom As Separation of 2'-fl from a fermentation broth
ES3011213T3 (en) 2015-12-18 2025-04-07 Glycom As Fermentative production of oligosaccharides
ES3060113T3 (en) 2016-08-31 2026-03-25 Oligoscience Biotechnology Gmbh Milk replacer composition comprising 2'-fucosyllactose for use in the treatment or prevention of gastro-intestinal diseases of production animals
ES2856749T3 (es) 2016-10-29 2021-09-28 Chr Hansen Hmo Gmbh Proceso para la producción de oligosacáridos fucosilados
WO2019003135A1 (en) 2017-06-30 2019-01-03 Glycom A/S PURIFICATION OF OLIGOSACCHARIDES
EP3425052A1 (en) 2017-07-07 2019-01-09 Jennewein Biotechnologie GmbH Fucosyltransferases and their use in producing fucosylated oligosaccharides
CN110914284B (zh) 2017-07-12 2025-01-07 格礼卡姆股份公司 包含中性单糖或寡糖和酸性非碳水化合物组分的无定形混合物
CN111356461A (zh) 2017-10-04 2020-06-30 加利福尼亚大学董事会 免疫调节性低聚糖
EP3486326A1 (en) 2017-11-21 2019-05-22 Jennewein Biotechnologie GmbH Method for the purification of n-acetylneuraminic acid from a fermentation broth
EP3494804B1 (en) 2017-12-08 2025-08-13 Chr. Hansen HMO GmbH Spray-dried 3-fucosyllactose
EP3524067B1 (en) 2018-02-08 2025-04-02 Chr. Hansen HMO GmbH Spray-dried mixture of human milk oligosaccharides
EP3494806B1 (en) 2017-12-08 2025-08-06 Chr. Hansen HMO GmbH Spray-dried lacto-n-fucopentaose
EP3494807A1 (en) 2017-12-11 2019-06-12 Jennewein Biotechnologie GmbH Spray-dried sialyllactose
SG11202004659QA (en) 2017-12-08 2020-06-29 Jennewein Biotechnologie Gmbh Spray-dried sialyllactose
EP3494805B1 (en) 2017-12-08 2025-08-13 Chr. Hansen HMO GmbH Spray-dried tetrasaccharides
AU2019362595B2 (en) 2018-10-18 2024-12-19 Basf Se Crystalline form II of 2'-O-fucosyllactose, process for its preparation, nutritional, cosmetic or pharmaceutical formulation containing the same
CA3122178A1 (en) 2018-12-19 2020-06-25 Basf Se Method for separating biomass from a solution comprising biomass and at least one oligosaccaride
WO2021019104A2 (en) 2019-09-18 2021-02-04 Basf Se A production host for producing human milk oligosaccharides
CN110672756B (zh) * 2019-11-07 2020-12-29 江南大学 一种奶粉中2’-岩藻糖基乳糖含量的检测方法
WO2021094133A2 (en) 2019-11-13 2021-05-20 Basf Se Enzymatic hydrolysis of 2',3-difucosyllactose
EP4077699A1 (en) 2019-12-19 2022-10-26 Basf Se Increasing space-time-yield, carbon-conversion-efficiency and carbon substrate flexibility in the production of fine chemicals
EP3848471A1 (en) 2020-01-10 2021-07-14 Chr. Hansen HMO GmbH Sequential fermentative production of oligosaccharides
CN115279778B (zh) 2020-03-12 2025-06-24 格礼卡姆股份公司 2’-fl的结晶
JP2023528657A (ja) 2020-06-12 2023-07-05 ビーエーエスエフ ソシエタス・ヨーロピア 発酵ブロスの改善された脱塩及び例えばオリゴ糖のファインケミカルの精製
EP3922727A1 (en) 2020-06-12 2021-12-15 Basf Se Method for separating biomass from a solution comprising biomass and at least one aroma compound
WO2022013143A1 (en) 2020-07-13 2022-01-20 Glycom A/S Oligosaccharide production
US20250320535A1 (en) 2021-05-17 2025-10-16 Dsm Ip Assets B.V. Novel technology to enable sucrose utilization in strains for biosynthetic production
AU2021446678A1 (en) 2021-05-20 2023-12-07 Chr. Hansen A/S Sequential fermentative production of oligosaccharides
JP2025528496A (ja) 2022-08-29 2025-08-28 クリスチャン・ハンセン・アクティーゼルスカブ 微生物発酵プロセスに由来する精製されたヒトミルクオリゴ糖の生産方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2125092C1 (ru) * 1991-10-15 1999-01-20 Дзе Скриппс Рисерч Инститьют Способ получения фукозилированного углевода, способ получения фукозилированной сиалилированной углеводной молекулы, реакционная система in vitro
US6238894B1 (en) 1998-11-04 2001-05-29 Diane Taylor α1,2 fucosyltransferase
CA2351022A1 (en) 1998-11-18 2000-05-25 Neose Technologies, Inc. Low cost manufacture of oligosaccharides
AU2001246894A1 (en) 2000-04-11 2001-10-23 Kyowa Hakko Kogyo Co. Ltd. Alpha1,2-fucosyltransferase and process for producing fucose-containing complex carbohydrate
ES2252261T3 (es) 2000-06-28 2006-05-16 Glycofi, Inc. Metodos para producir glicoproteinas modificadas.
US20020132320A1 (en) 2001-01-10 2002-09-19 Wang Peng George Glycoconjugate synthesis using a pathway-engineered organism
ATE468391T1 (de) * 2001-08-24 2010-06-15 Kyowa Hakko Bio Co Ltd Alpha-1,2-fucosyl-transferase und diese codierende dna
FR2840920B1 (fr) * 2002-06-18 2006-06-23 Biochimie Appliquee Soc Nouveau microorganisme de la famille des enterobacteriaceae
WO2005055944A2 (en) 2003-12-05 2005-06-23 Cincinnati Children's Hospital Medical Center Oligosaccharide compositions and use thereof in the treatment of infection
US7326770B2 (en) * 2004-01-22 2008-02-05 Neose Technologies, Inc. H. pylori fucosyltransferases
US20080145899A1 (en) * 2004-09-17 2008-06-19 Neose Technologies Inc Production of Oligosaccharides By Microorganisms
EP1899452B1 (en) * 2005-06-17 2010-10-20 Ajinomoto Co., Inc. A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family with enhanced expression of the fucpikur operon
WO2007101862A1 (en) * 2006-03-09 2007-09-13 Centre National De La Recherche Scientifique (Cnrs) Method of producing sialylated oligosaccharides
US20070221747A1 (en) 2006-03-22 2007-09-27 Siemens Vdo Automotive Corporation Super imposed signal for an actuator and heater of a fuel injector
AU2008227024A1 (en) * 2007-03-07 2008-09-18 Glycofi, Inc. Production of glycoproteins with modified fucosylation

Also Published As

Publication number Publication date
EP2379708A1 (en) 2011-10-26
US20190382737A1 (en) 2019-12-19
JP2012512643A (ja) 2012-06-07
NZ593448A (en) 2012-06-29
IN2011MU01050A (pt) 2011-12-30
HK1159173A1 (zh) 2012-07-27
CO6362044A2 (es) 2012-01-20
AU2009329543A1 (en) 2010-06-24
BRPI0923433B1 (pt) 2021-06-01
US11390855B2 (en) 2022-07-19
JP5726751B2 (ja) 2015-06-03
RU2011129780A (ru) 2013-01-27
SG171814A1 (en) 2011-07-28
CN102257128A (zh) 2011-11-23
EP2379708B1 (en) 2016-04-27
US20110300584A1 (en) 2011-12-08
AU2009329543B2 (en) 2015-04-16
WO2010070104A1 (en) 2010-06-24
RU2584599C2 (ru) 2016-05-20
MY183602A (en) 2021-03-02
MX325472B (pt) 2014-11-20
MX2011006371A (es) 2011-09-27

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Legal Events

Date Code Title Description
B15K Others concerning applications: alteration of classification

Ipc: C12N 9/12 (2006.01), A23L 33/00 (2016.01), C12N 9/

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B09W Correction of the decision to grant [chapter 9.1.4 patent gazette]

Free format text: RETIFICACAO DA PUBLICACAO DEVIDO A I NCORRECOES NO QUADRO 1 DO PARECER DE DEFERIMENTO.

B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 18/12/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B25D Requested change of name of applicant approved

Owner name: CHR. HANSEN HMO GMBH (DE)