BRPI0923498A2 - amidos de diidropiridona como moduladores de p2x7 - Google Patents
amidos de diidropiridona como moduladores de p2x7Info
- Publication number
- BRPI0923498A2 BRPI0923498A2 BRPI0923498A BRPI0923498A BRPI0923498A2 BR PI0923498 A2 BRPI0923498 A2 BR PI0923498A2 BR PI0923498 A BRPI0923498 A BR PI0923498A BR PI0923498 A BRPI0923498 A BR PI0923498A BR PI0923498 A2 BRPI0923498 A2 BR PI0923498A2
- Authority
- BR
- Brazil
- Prior art keywords
- dihydropyridone
- starches
- modulators
- dihydropyridone starches
- Prior art date
Links
- ZPOODPZCZLCUAN-UHFFFAOYSA-N 3,4-dihydro-1h-pyridin-2-one Chemical compound O=C1CCC=CN1 ZPOODPZCZLCUAN-UHFFFAOYSA-N 0.000 title 1
- 229920002472 Starch Polymers 0.000 title 1
- 235000019698 starch Nutrition 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20348208P | 2008-12-23 | 2008-12-23 | |
| PCT/EP2009/067026 WO2010072597A1 (en) | 2008-12-23 | 2009-12-14 | Dihydropyridone amides as p2x7 modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0923498A2 true BRPI0923498A2 (pt) | 2019-09-24 |
Family
ID=41664810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0923498A BRPI0923498A2 (pt) | 2008-12-23 | 2009-12-14 | amidos de diidropiridona como moduladores de p2x7 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8372865B2 (pt) |
| EP (1) | EP2385939A1 (pt) |
| JP (1) | JP5478637B2 (pt) |
| KR (1) | KR101381074B1 (pt) |
| CN (1) | CN102264723B (pt) |
| AR (1) | AR074843A1 (pt) |
| AU (1) | AU2009331659B2 (pt) |
| BR (1) | BRPI0923498A2 (pt) |
| CA (1) | CA2745864A1 (pt) |
| IL (1) | IL213417A0 (pt) |
| MX (1) | MX2011006232A (pt) |
| SG (1) | SG172336A1 (pt) |
| TW (1) | TW201028396A (pt) |
| WO (1) | WO2010072597A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2783236C (en) | 2009-12-08 | 2020-03-10 | Vanderbilt University | Improved methods and compositions for vein harvest and autografting |
| WO2015099107A1 (ja) | 2013-12-26 | 2015-07-02 | 塩野義製薬株式会社 | 含窒素６員環誘導体およびそれらを含有する医薬組成物 |
| JP6759514B2 (ja) | 2014-08-01 | 2020-09-23 | ヌエヴォリューション・アクティーゼルスカブＮｕｅｖｏｌｕｔｉｏｎ Ａ／Ｓ | ブロモドメインに対して活性な化合物 |
| US10774051B2 (en) | 2015-04-24 | 2020-09-15 | Shionogi & Co., Ltd. | 6-membered heterocyclic derivatives and pharmaceutical composition comprising the same |
| KR20180134860A (ko) | 2016-02-15 | 2018-12-19 | 체엠엠 - 포르슝스첸트룸 퓨어 몰레쿨라레 메디친 게엠베하 | 암의 치료를 위한 taf1 억제제 |
| WO2018074390A1 (ja) | 2016-10-17 | 2018-04-26 | 塩野義製薬株式会社 | 二環性含窒素複素環誘導体およびそれらを含有する医薬組成物 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2051705A1 (en) * | 1990-06-19 | 1991-12-20 | Kiyoaki Katano | Pyridine derivatives having angiotensin ii antagonism |
| CZ403592A3 (en) | 1992-02-20 | 1993-12-15 | Hoechst Ag | Arylcarbonylaminoalkyldihydrooxopyridines, process of their preparation and their use |
| DE4206045A1 (de) | 1992-02-27 | 1993-09-02 | Bayer Ag | Sulfonylbenzyl substituierte pyridone |
| DE4215587A1 (de) | 1992-05-12 | 1993-11-18 | Bayer Ag | Sulfonylbenzyl-substituierte Benzo- und Pyridopyridone |
| SE9704544D0 (sv) * | 1997-12-05 | 1997-12-05 | Astra Pharma Prod | Novel compounds |
| TR200002182T2 (tr) | 1998-01-27 | 2000-12-21 | Aventis Pharmaceuticals Products Inc. | İkame edilmiş aksozaherosayklil faktör xa inhibitörleri |
| ES2320973T3 (es) | 2000-06-12 | 2009-06-01 | EISAI R&D MANAGEMENT CO., LTD. | Compuestos de 1,2-dihidropiridina, procedimiento para su preparacion y uso de los mismos. |
| GB0129260D0 (en) | 2001-12-06 | 2002-01-23 | Eisai London Res Lab Ltd | Pharmaceutical compositions and their uses |
| JP2005170790A (ja) | 2002-01-09 | 2005-06-30 | Ajinomoto Co Inc | Ｎ−アルキルスルフォニル置換アミド誘導体 |
| JP4857128B2 (ja) * | 2004-02-20 | 2012-01-18 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | 新規な化合物 |
| SA05260265A (ar) | 2004-08-30 | 2005-12-03 | استرازينيكا ايه بي | مركبات جديدة |
| FR2878528B1 (fr) | 2004-11-29 | 2008-05-16 | Aventis Pharma Sa | 2-alcoxy-3,4,5-trihydroxy-alkylamides, leur preparation, compositions les contenant et utilisation |
| AU2006232517A1 (en) | 2005-04-04 | 2006-10-12 | Eisai R&D Management Co., Ltd. | Dihydropyridine compounds and compositions for headaches |
| BRPI0607913A2 (pt) | 2005-04-08 | 2010-03-23 | Eisai R&D Man Co Ltd | agente terapÊutico para discinesia |
| US7880004B2 (en) | 2005-09-15 | 2011-02-01 | Bristol-Myers Squibb Company | Met kinase inhibitors |
| WO2008104472A1 (en) | 2007-02-28 | 2008-09-04 | F. Hoffmann-La Roche Ag | 2, 4 -diaminopyrimidine derivatives and their use as p2x antagonists or as prodrugs thereof |
| GB0705882D0 (en) * | 2007-03-27 | 2007-05-02 | Glaxo Group Ltd | Novel compounds |
| EP2139858A1 (en) * | 2007-03-28 | 2010-01-06 | Glaxo Group Limited | Piperidinone carboxamide derivatives as p2x7 modulators |
| WO2008119685A2 (en) * | 2007-03-29 | 2008-10-09 | Glaxo Group Limited | Oxazolidine and morpholine carboxamide derivatives as p2x7 modulators |
| US20100056595A1 (en) * | 2007-04-11 | 2010-03-04 | Glaxo Group Limited | Pyrazole Derivatives as P2X7 Modulators |
| EP2391604A1 (en) * | 2008-12-23 | 2011-12-07 | F. Hoffmann-La Roche AG | Dihydropyridone amides as p2x7 modulators |
-
2009
- 2009-12-14 CN CN200980152176.6A patent/CN102264723B/zh not_active Expired - Fee Related
- 2009-12-14 BR BRPI0923498A patent/BRPI0923498A2/pt not_active IP Right Cessation
- 2009-12-14 AU AU2009331659A patent/AU2009331659B2/en not_active Ceased
- 2009-12-14 SG SG2011045945A patent/SG172336A1/en unknown
- 2009-12-14 JP JP2011542760A patent/JP5478637B2/ja not_active Expired - Fee Related
- 2009-12-14 WO PCT/EP2009/067026 patent/WO2010072597A1/en not_active Ceased
- 2009-12-14 KR KR1020117014366A patent/KR101381074B1/ko not_active Expired - Fee Related
- 2009-12-14 EP EP09775181A patent/EP2385939A1/en not_active Withdrawn
- 2009-12-14 MX MX2011006232A patent/MX2011006232A/es active IP Right Grant
- 2009-12-14 CA CA2745864A patent/CA2745864A1/en not_active Abandoned
- 2009-12-15 US US12/637,984 patent/US8372865B2/en not_active Expired - Fee Related
- 2009-12-21 TW TW098143978A patent/TW201028396A/zh unknown
- 2009-12-22 AR ARP090105035A patent/AR074843A1/es unknown
-
2011
- 2011-06-06 IL IL213417A patent/IL213417A0/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009331659B2 (en) | 2015-09-03 |
| CN102264723B (zh) | 2014-12-10 |
| KR101381074B1 (ko) | 2014-04-11 |
| IL213417A0 (en) | 2011-07-31 |
| KR20110086768A (ko) | 2011-07-29 |
| AR074843A1 (es) | 2011-02-16 |
| US8372865B2 (en) | 2013-02-12 |
| EP2385939A1 (en) | 2011-11-16 |
| TW201028396A (en) | 2010-08-01 |
| JP5478637B2 (ja) | 2014-04-23 |
| JP2012513433A (ja) | 2012-06-14 |
| WO2010072597A1 (en) | 2010-07-01 |
| MX2011006232A (es) | 2011-06-24 |
| CA2745864A1 (en) | 2010-07-01 |
| CN102264723A (zh) | 2011-11-30 |
| SG172336A1 (en) | 2011-07-28 |
| US20100160373A1 (en) | 2010-06-24 |
| AU2009331659A1 (en) | 2011-06-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2420634A4 (en) | CONNECTOR | |
| BRPI1010210A2 (pt) | membro de fixação arqueado | |
| BRPI0921327A2 (pt) | Combinação de herbicida-protetor | |
| BRPI1012353A2 (pt) | montagem de bucha | |
| PT2496567T (pt) | Novos moduladores de quinase benzopiran | |
| BRPI1012549A2 (pt) | moduladores do regulador da condutância da transmembrana de fibrose | |
| BRPI0919625A2 (pt) | piriridina, piridina bicíclica e análogos relacionados como moduladores de sirtuína | |
| EP2406768A4 (en) | DISTRIBUTION BACKBONE | |
| BRPI0809930A2 (pt) | Derivados de carboxamida imidazolidina como moduladores de p2x7 | |
| BRPI1008939A2 (pt) | 2-mercaptoquinolina-3-carboxamidas substituídas como moduladores de kncq2/3. | |
| BR112013015260A2 (pt) | derivados de enxofre como moduladores de receptor de quimiocina | |
| BRPI0822058A2 (pt) | Derivados de 5-oxo-3-pirrolidinacarboxamida como moduladores de p2x7 | |
| CU23870B1 (es) | Derivados de ciclopropilamida como moduladores h3 | |
| BRPI0906959A2 (pt) | Variantes de celulase com inibição reduzida por glicose | |
| EP2474324A4 (en) | COATING COMPOSITION | |
| BRPI0924059A2 (pt) | Didro piridona amidas como moduladores de p2x7 | |
| BRPI0821498A2 (pt) | Estrutura de queimador | |
| EP2259958A4 (en) | LINKAGE | |
| BRPI1009428A2 (pt) | 3-aminoisoxazolopiridina substituída como moduladores de kcnq2/3 | |
| EP2310699A4 (en) | WASHER | |
| BR112013013883A2 (pt) | fibras de degradação controlada | |
| BRPI0822525A2 (pt) | gerar mapas de sites | |
| FR2947857B1 (fr) | Agencement de deshuileur | |
| EP2334424A4 (en) | VISCOSITY REDUCTION | |
| BR112013011865A2 (pt) | moduladores de gpr119 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |