BRPI0924653A2 - composto de ferro-oligossacarídeo estável - Google Patents

composto de ferro-oligossacarídeo estável

Info

Publication number: BRPI0924653A2
Authority: BR; Brazil
Prior art keywords: oligosaccharide compound; stable iron; iron oligosaccharide; stable; compound
Prior art date: 2009-03-25

Application number

BRPI0924653A

Other languages

English (en)

Inventor

Hans Andreasen

Original Assignee

Pharmacosmos Holding As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-03-25

Filing date

2009-03-25

Publication date

2016-01-26

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41350678&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0924653(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-03-25 Application filed by Pharmacosmos Holding As filed Critical Pharmacosmos Holding As

2016-01-26 Publication of BRPI0924653A2 publication Critical patent/BRPI0924653A2/pt

2019-10-08 Publication of BRPI0924653B1 publication Critical patent/BRPI0924653B1/pt

2021-05-25 Publication of BRPI0924653B8 publication Critical patent/BRPI0924653B8/pt

Links

XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 title 1
229910052742 iron Inorganic materials 0.000 title 1
-1 iron oligosaccharide compound Chemical class 0.000 title 1
229920001542 oligosaccharide Polymers 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/721—Dextrans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Chemistry (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Bioinformatics & Cheminformatics (AREA)
Materials Engineering (AREA)
Polymers & Plastics (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Hematology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Nutrition Science (AREA)
Dermatology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Optical Recording Or Reproduction (AREA)

BRPI0924653A 2009-03-25 2009-03-25 composto de ferro-oligossacarídeo, composição e uso de deste composto BRPI0924653B8 (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/DK2009/050069 WO2010108493A1 (en)	2009-03-25	2009-03-25	A stable iron oligosaccharide compound

Publications (3)

Publication Number	Publication Date
BRPI0924653A2 true BRPI0924653A2 (pt)	2016-01-26
BRPI0924653B1 BRPI0924653B1 (pt)	2019-10-08
BRPI0924653B8 BRPI0924653B8 (pt)	2021-05-25

Family

ID=41350678

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0924653A BRPI0924653B8 (pt)	2009-03-25	2009-03-25	composto de ferro-oligossacarídeo, composição e uso de deste composto

Country Status (25)

Country	Link
US (8)	US8815301B2 (pt)
EP (4)	EP3821910B1 (pt)
JP (1)	JP5426010B2 (pt)
KR (1)	KR101580348B1 (pt)
CN (3)	CN109700828A (pt)
AU (1)	AU2009342799B2 (pt)
BR (1)	BRPI0924653B8 (pt)
CA (1)	CA2756580A1 (pt)
CY (2)	CY1118725T1 (pt)
DK (2)	DK2411053T3 (pt)
EA (1)	EA023917B1 (pt)
ES (3)	ES3009818T3 (pt)
HR (3)	HRP20250214T1 (pt)
HU (2)	HUE052617T2 (pt)
LT (2)	LT3156075T (pt)
MX (1)	MX2011009936A (pt)
NZ (1)	NZ595597A (pt)
PH (1)	PH12015500891B1 (pt)
PL (3)	PL2411053T3 (pt)
PT (2)	PT3156075T (pt)
RS (2)	RS55700B1 (pt)
SI (2)	SI3156075T1 (pt)
UA (1)	UA103373C2 (pt)
WO (1)	WO2010108493A1 (pt)
ZA (1)	ZA201107431B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT1973549T (pt)	2006-01-06	2016-10-25	Luitpold Pharm Inc	Métodos e composições para administração de ferro
CN109700828A (zh)	2009-03-25	2019-05-03	法码科思莫斯控股有限公司	稳定的铁寡糖复合物
CN103626807B (zh) *	2013-11-20	2017-07-07	青岛国风药业股份有限公司	一种多糖铁复合物的制备方法及其质量检测方法
CZ2014451A3 (cs) *	2014-06-30	2016-01-13	Contipro Pharma A.S.	Protinádorová kompozice na bázi kyseliny hyaluronové a anorganických nanočástic, způsob její přípravy a použití
WO2016066172A1 (en) *	2014-10-27	2016-05-06	Pharmacosmos Holding A/S	Treatment or prevention of anaemia in pregnant non-human mammals
BR112017028025B1 (pt) *	2015-06-22	2023-04-18	Pharmacosmos Holding A/S	Usos de um complexo de ferro-carboidrato para o tratamento ou prevenção de uma deficiência de ferro de um feto ou de um bebê
CA2932075C (en) *	2015-09-01	2020-11-17	Particle Dynamics International, Llc	Iron-polysaccharide complexes and methods for the preparation thereof
US10258647B2 (en)	2015-09-01	2019-04-16	Particle Dynamics International, Llc	Iron-polysaccharide complexes and methods for the preparation thereof
CN105908611A (zh) *	2016-06-12	2016-08-31	天津康远工程机械有限公司	具有清洗功能的自动找平双层预应力烫平板
EP3450443A1 (en)	2017-08-29	2019-03-06	Jennewein Biotechnologie GmbH	Process for purifying sialylated oligosaccharides
ES3009466T3 (en)	2017-09-11	2025-03-27	Pharmacosmos Holding As	Iron complex compounds for therapeutic use
CN109646454A (zh) *	2018-12-29	2019-04-19	博瑞生物医药（苏州）股份有限公司	异麦芽糖酐铁1000的制备方法
SG11202107050RA (en) *	2019-01-10	2021-07-29	Pharmacosmos Holding As	Treating iron deficiency in subjects at risk of cardiovascular adverse events and iron for the management of atrial fibrillation
EA202191858A1 (ru)	2019-06-12	2021-11-12	Фармакосмос Холдинг А/С	Лечение дефицита железа у субъектов с риском нежелательных явлений со стороны сердечно-сосудистой системы и железо для лечения фибрилляции предсердий
US11447513B2 (en) *	2020-02-12	2022-09-20	Rk Pharma Inc.	Purification process of ferric carboxymaltose
CA3226771A1 (en)	2021-08-03	2023-02-09	Pharmacosmos Holding A/S	Iron complex compounds for subcutaneous use in therapy of iron deficiency in companion animals
WO2024069644A1 (en) *	2022-09-30	2024-04-04	West Bengal Chemical Industries Limited	A pharmaceutically acceptable ferric carboxymaltose and preparation thereof
CN116726045B (zh) *	2023-06-30	2024-03-19	重庆汉佩生物科技有限公司	一种氟雷拉纳组合物
CN116672360B (zh) *	2023-06-30	2024-05-14	重庆汉佩生物科技有限公司	一种妥曲珠利与葡庚糖酐铁的组合物
WO2025215563A2 (en) *	2024-04-11	2025-10-16	Rk Pharma Inc	Preparation of stable ferric derisomaltose
WO2026017901A1 (en)	2024-07-18	2026-01-22	Malian Biologicals Gmbh	Iron supplementation in neurodevelopmental or psychiatric disorder

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CA623412A (en)		1961-07-04	Muller Arthur	Iron polyisomaltose complexes for therapeutical application
CA623411A (en)		1961-07-04	Muller Arthur	Process for the manufacture of iron-polyisomaltose complex for therapeutical purposes
US2807610A (en) *	1952-02-15	1957-09-24	Baker Chem Co J T	Hydrogenated dextran
US3100202A (en)	1960-06-17	1963-08-06	Muller Arthur	Process for preparing an iron hydroxide polyisomaltose complex and the resulting product
US3076798A (en)	1961-02-23	1963-02-05	Hausmann Lab Ltd	Process for preparing a ferric hydroxide polymaltose complex
DE1293144B (de)	1964-11-04	1969-04-24	Hausmann Ag Labor	Verfahren zur Herstellung von Komplexverbindungen des Eisens mit Sorbit, Gluconsaeure und einem Oligosaccharid
US3639588A (en)	1966-10-22	1972-02-01	Fisons Pharmaceuticals Ltd	Pharmaceutical compositions containing ferric hydroxide complexed with dextran or dextrin heptonic acids
GB1594697A (en) *	1977-04-19	1981-08-05	Pharmacia Ab	Oligosaccharide compositions for parenteral use
DE3026868C2 (de)	1980-07-16	1986-03-13	Laboratorien Hausmann AG, St. Gallen	Verfahren zur Herstellung von Eisen(III)hydroxid-Dextran-Komplexen und sie enthaltende pharmazeutische sterile wäßrige Lösung
US4518581A (en) *	1981-11-02	1985-05-21	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	Imparting low- or anti-cariogenic property to orally-usable products
DE3422249A1 (de)	1984-06-15	1985-12-19	Pfeifer & Langen, 5000 Köln	Wasserloesliches eisendextran und verfahren zu seiner herstellung
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US6219440B1 (en)	1997-01-17	2001-04-17	The University Of Connecticut	Method and apparatus for modeling cellular structure and function
DK172860B1 (da)	1998-03-25	1999-08-16	Pharmacosmos Holding As	Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman
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DE10249552A1 (de)	2002-10-23	2004-05-13	Vifor (International) Ag	Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel
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SI1848446T1 (sl) *	2005-02-09	2010-01-29	Vifor Int Ag	Uporaba Ĺľelezove(III)-kompleksne spojine
ITMO20050056A1 (it)	2005-03-15	2006-09-16	Biofer Spa	Processo per la preparazione di complessi del ferro trivalente con zuccheri mono-, di- e polisaccaridi.
CN100528237C (zh) *	2005-04-26	2009-08-19	重庆医药工业研究院有限责任公司	多核的氢氧化铁-糖复合物的制备方法
EP1757299A1 (de)	2005-08-25	2007-02-28	Vifor (International) Ag	Eisen(III)-Komplexverbindungen zur Behandlung von Eisenmangel-Zuständen bei Patienten mit chronisch-entzündlicher Darmerkrankung
PT1973549T (pt)	2006-01-06	2016-10-25	Luitpold Pharm Inc	Métodos e composições para administração de ferro
EP1997833A1 (de)	2007-05-29	2008-12-03	Vifor (International) Ag	Wasserlösliche Eisen-Kohlenhydratderivat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel
CN109700828A (zh)	2009-03-25	2019-05-03	法码科思莫斯控股有限公司	稳定的铁寡糖复合物
US20150202224A1 (en)	2012-07-27	2015-07-23	Luitpold Pharmaceuticals, Inc.	Method of treating iron deficiency anemia
WO2014071194A2 (en)	2012-11-01	2014-05-08	Katz Robert S	Methods for treating fibromyalgia
AU2013351058B2 (en)	2012-11-30	2017-03-16	Pharmacosmos Holding A/S	Cryoprotecting agent, cryoprotecting and cryopreserved compositions, uses thereof, and methods of cryopreservation

2009
- 2009-03-25 CN CN201810296939.5A patent/CN109700828A/zh active Pending
- 2009-03-25 HU HUE16201189A patent/HUE052617T2/hu unknown
- 2009-03-25 SI SI200932104T patent/SI3156075T1/sl unknown
- 2009-03-25 LT LTEP16201189.4T patent/LT3156075T/lt unknown
- 2009-03-25 EP EP20200455.2A patent/EP3821910B1/en active Active
- 2009-03-25 HR HRP20250214TT patent/HRP20250214T1/hr unknown
- 2009-03-25 DK DK09776213.2T patent/DK2411053T3/en active
- 2009-03-25 ES ES20200455T patent/ES3009818T3/es active Active
- 2009-03-25 BR BRPI0924653A patent/BRPI0924653B8/pt active IP Right Grant
- 2009-03-25 PT PT162011894T patent/PT3156075T/pt unknown
- 2009-03-25 AU AU2009342799A patent/AU2009342799B2/en active Active
- 2009-03-25 SI SI200931621A patent/SI2411053T1/sl unknown
- 2009-03-25 EA EA201190214A patent/EA023917B1/ru not_active IP Right Cessation
- 2009-03-25 PL PL09776213T patent/PL2411053T3/pl unknown
- 2009-03-25 CN CN2009801582967A patent/CN102361651A/zh active Pending
- 2009-03-25 ES ES16201189T patent/ES2840074T3/es active Active
- 2009-03-25 CN CN201810292732.0A patent/CN108752395A/zh active Pending
- 2009-03-25 DK DK16201189.4T patent/DK3156075T3/da active
- 2009-03-25 US US13/138,669 patent/US8815301B2/en active Active
- 2009-03-25 CA CA2756580A patent/CA2756580A1/en not_active Abandoned
- 2009-03-25 EP EP16201189.4A patent/EP3156075B1/en active Active
- 2009-03-25 HR HRP20170230TT patent/HRP20170230T1/hr unknown
- 2009-03-25 EP EP24221302.3A patent/EP4545137A3/en active Pending
- 2009-03-25 PL PL16201189T patent/PL3156075T3/pl unknown
- 2009-03-25 RS RS20170157A patent/RS55700B1/sr unknown
- 2009-03-25 JP JP2012501133A patent/JP5426010B2/ja active Active
- 2009-03-25 UA UAA201111767A patent/UA103373C2/ru unknown
- 2009-03-25 ES ES09776213.2T patent/ES2617658T3/es active Active
- 2009-03-25 HU HUE09776213A patent/HUE030866T2/en unknown
- 2009-03-25 NZ NZ595597A patent/NZ595597A/xx unknown
- 2009-03-25 WO PCT/DK2009/050069 patent/WO2010108493A1/en not_active Ceased
- 2009-03-25 LT LTEP09776213.2T patent/LT2411053T/lt unknown
- 2009-03-25 PT PT97762132T patent/PT2411053T/pt unknown
- 2009-03-25 KR KR1020117025035A patent/KR101580348B1/ko active Active
- 2009-03-25 EP EP09776213.2A patent/EP2411053B1/en active Active
- 2009-03-25 MX MX2011009936A patent/MX2011009936A/es active IP Right Grant
- 2009-03-25 PL PL20200455.2T patent/PL3821910T3/pl unknown
- 2009-03-25 RS RS20201417A patent/RS61104B1/sr unknown
2011
- 2011-10-11 ZA ZA2011/07431A patent/ZA201107431B/en unknown
2014
- 2014-06-18 US US14/307,957 patent/US9439969B2/en active Active
- 2014-06-18 US US14/308,198 patent/US20140364598A1/en not_active Abandoned
2015
- 2015-04-21 PH PH12015500891A patent/PH12015500891B1/en unknown
2016
- 2016-07-28 US US15/222,306 patent/US10865255B2/en active Active
2017
- 2017-02-20 CY CY20171100226T patent/CY1118725T1/el unknown
2018
- 2018-11-02 US US16/178,943 patent/US10414831B2/en active Active
2020
- 2020-10-29 US US17/083,366 patent/US12030962B2/en active Active
- 2020-11-30 HR HRP20201903TT patent/HRP20201903T1/hr unknown
- 2020-12-23 CY CY20201101214T patent/CY1123651T1/el unknown
2021
- 2021-01-06 US US17/142,442 patent/US11851504B2/en active Active
2024
- 2024-06-06 US US18/735,261 patent/US20250026864A1/en active Pending

Also Published As

Publication number	Publication date
UA103373C2 (ru)	2013-10-10
US20210108004A1 (en)	2021-04-15
ES2840074T3 (es)	2021-07-06
HUE052617T2 (hu)	2021-05-28
PT3156075T (pt)	2021-01-05
ES2617658T3 (es)	2017-06-19
CN102361651A (zh)	2012-02-22
EP3821910A1 (en)	2021-05-19
CY1123651T1 (el)	2022-03-24
US20210130505A1 (en)	2021-05-06
US12030962B2 (en)	2024-07-09
PT2411053T (pt)	2017-02-15
US20120010166A1 (en)	2012-01-12
CY1118725T1 (el)	2017-07-12
HK1164138A1 (en)	2012-09-21
CA2756580A1 (en)	2010-09-30
EP3156075A1 (en)	2017-04-19
HRP20201903T1 (hr)	2021-01-22
AU2009342799A1 (en)	2011-11-03
US20160333118A1 (en)	2016-11-17
KR20120016063A (ko)	2012-02-22
CN108752395A (zh)	2018-11-06
RS61104B1 (sr)	2020-12-31
EP3821910C0 (en)	2024-12-25
PL2411053T3 (pl)	2017-06-30
LT2411053T (lt)	2017-04-10
EP4545137A2 (en)	2025-04-30
HRP20250214T1 (hr)	2025-04-25
DK2411053T3 (en)	2017-02-20
KR101580348B1 (ko)	2016-01-04
US9439969B2 (en)	2016-09-13
CN109700828A (zh)	2019-05-03
US20190135947A1 (en)	2019-05-09
US11851504B2 (en)	2023-12-26
US20140364598A1 (en)	2014-12-11
MX2011009936A (es)	2011-10-06
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