BRPI0925048A2 - Módulo para produção de comprimidos e método para a produção contínua de comprimidos - Google Patents
Módulo para produção de comprimidos e método para a produção contínua de comprimidosInfo
- Publication number
- BRPI0925048A2 BRPI0925048A2 BRPI0925048-4A BRPI0925048A BRPI0925048A2 BR PI0925048 A2 BRPI0925048 A2 BR PI0925048A2 BR PI0925048 A BRPI0925048 A BR PI0925048A BR PI0925048 A2 BRPI0925048 A2 BR PI0925048A2
- Authority
- BR
- Brazil
- Prior art keywords
- tablet production
- continuous
- production method
- module
- production module
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
- B29B13/00—Conditioning or physical treatment of the material to be shaped
- B29B13/06—Conditioning or physical treatment of the material to be shaped by drying
- B29B13/065—Conditioning or physical treatment of the material to be shaped by drying of powder or pellets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
- B29B7/00—Mixing; Kneading
- B29B7/30—Mixing; Kneading continuous, with mechanical mixing or kneading devices
- B29B7/34—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices
- B29B7/38—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary
- B29B7/46—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with more than one shaft
- B29B7/48—Mixing; Kneading continuous, with mechanical mixing or kneading devices with movable mixing or kneading devices rotary with more than one shaft with intermeshing devices, e.g. screws
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
- B29B7/00—Mixing; Kneading
- B29B7/30—Mixing; Kneading continuous, with mechanical mixing or kneading devices
- B29B7/58—Component parts, details or accessories; Auxiliary operations
- B29B7/72—Measuring, controlling or regulating
- B29B7/726—Measuring properties of mixture, e.g. temperature or density
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/02—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/32—Component parts, details or accessories; Auxiliary operations
- B29C43/34—Feeding the material to the mould or the compression means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/32—Component parts, details or accessories; Auxiliary operations
- B29C43/50—Removing moulded articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/32—Component parts, details or accessories; Auxiliary operations
- B29C43/58—Measuring, controlling or regulating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
- B30B11/005—Control arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B30—PRESSES
- B30B—PRESSES IN GENERAL
- B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
- B30B15/30—Feeding material to presses
- B30B15/302—Feeding material in particulate or plastic state to moulding presses
- B30B15/308—Feeding material in particulate or plastic state to moulding presses in a continuous manner, e.g. for roller presses, screw extrusion presses
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/32—Component parts, details or accessories; Auxiliary operations
- B29C43/58—Measuring, controlling or regulating
- B29C2043/5833—Measuring, controlling or regulating movement of moulds or mould parts, e.g. opening or closing, actuating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/0005—Condition, form or state of moulded material or of the material to be shaped containing compounding ingredients
- B29K2105/0035—Medical or pharmaceutical agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/25—Solid
- B29K2105/251—Particles, powder or granules
Landscapes
- Mechanical Engineering (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2009/051885 WO2010128359A1 (en) | 2009-05-07 | 2009-05-07 | Tablet production module and method for continuous production of tablets |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0925048A2 true BRPI0925048A2 (pt) | 2015-08-04 |
| BRPI0925048B1 BRPI0925048B1 (pt) | 2019-07-09 |
| BRPI0925048B8 BRPI0925048B8 (pt) | 2021-06-22 |
Family
ID=41479620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0925048A BRPI0925048B8 (pt) | 2009-05-07 | 2009-05-07 | módulo para produção de comprimidos e método para a produção contínua de comprimidos |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9713575B2 (pt) |
| EP (1) | EP2427166B1 (pt) |
| JP (1) | JP2012525895A (pt) |
| CN (1) | CN102438578A (pt) |
| BR (1) | BRPI0925048B8 (pt) |
| DK (1) | DK2427166T3 (pt) |
| ES (1) | ES2441446T3 (pt) |
| HR (1) | HRP20131155T1 (pt) |
| PT (1) | PT2427166E (pt) |
| WO (1) | WO2010128359A1 (pt) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1945632B1 (en) | 2005-11-08 | 2013-09-18 | Vertex Pharmaceuticals Incorporated | Heterocyclic modulators of atp-binding cassette transporters |
| US8969386B2 (en) | 2007-05-09 | 2015-03-03 | Vertex Pharmaceuticals Incorporated | Modulators of CFTR |
| SI2225230T1 (sl) | 2007-12-07 | 2017-03-31 | Vertex Pharmaceuticals Incorporated | Trdne oblike 3-(6-(1-2,2-difluorobenzo(d)(1,3)dioxol-5-il)ciklopropan- karboksamido)-3-metilpiridin-2-il) benzojske kisline |
| EP2639224B1 (en) | 2007-12-07 | 2016-08-24 | Vertex Pharmaceuticals Incorporated | Process for producing cycloalkylcarboxiamido-pyridine benzoic acids |
| NZ720282A (en) | 2008-02-28 | 2017-12-22 | Vertex Pharma | Heteroaryl derivatives as cftr modulators |
| HRP20211752T1 (hr) | 2010-04-07 | 2022-02-18 | Vertex Pharmaceuticals Incorporated | Farmaceutski pripravci 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioksol-5-il)ciklopropankarboksamido)-3-metilpiridin-2-il)benzojeve kiseline i njihova primjena |
| WO2013112804A1 (en) * | 2012-01-25 | 2013-08-01 | Vertex Pharmaceuticals Incorporated | Formulations of 3-(6-(1-(2.2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid |
| US20150183531A1 (en) * | 2012-06-04 | 2015-07-02 | Bart Peter Verhoest | Feeder Unit, a Feeder Module Comprising a plurality of Feeder Units, and Method for Discharging a Constant Mass Flow of One or More Powders Into a Receiving Container |
| WO2013182870A1 (en) | 2012-06-04 | 2013-12-12 | Gea Process Engineering Nv | Feeder module and method for providing a mixture of one or more powders to a receiving container |
| WO2014207510A1 (en) | 2013-06-27 | 2014-12-31 | Gea Process Engineering Nv | Method for continuous production of tablets, tabletting system for carrying out the method, and use of the tabletting system for the production of tablets of at least two ingredients containing particles with a significant difference in particle size |
| US10260807B2 (en) | 2013-07-05 | 2019-04-16 | Freund Corporation | Drying device and continuous granule production system |
| JP6963896B2 (ja) * | 2013-11-12 | 2021-11-10 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | Cftr媒介性疾患の処置のための医薬組成物を調製する方法 |
| US10780410B2 (en) | 2014-08-15 | 2020-09-22 | Massachusetts Institute Of Technology | Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients |
| PT3221692T (pt) | 2014-11-18 | 2021-09-10 | Vertex Pharma | Processo de realização de testagem de alta produtividade por cromatografia líquida de alta eficiência |
| JP6606747B2 (ja) | 2015-06-15 | 2019-11-20 | 株式会社菊水製作所 | 粉体混合供給装置及びこれを用いた粉体圧縮成形機 |
| DE102015116565B4 (de) | 2015-09-30 | 2018-03-01 | Fette Compacting Gmbh | Verfahren zum Betreiben einer Rundläufer-Tablettenpresse und Rundläufer-Tablettenpresse |
| US10689873B2 (en) | 2016-03-10 | 2020-06-23 | Lonza Ltd | Customizable facility |
| WO2017156420A1 (en) | 2016-03-10 | 2017-09-14 | Lonza Ltd | Customizable facility |
| JP6681756B2 (ja) * | 2016-03-16 | 2020-04-15 | 株式会社菊水製作所 | 回転式粉体圧縮成形機の制御装置 |
| JP6775311B2 (ja) * | 2016-03-29 | 2020-10-28 | 株式会社菊水製作所 | 成形品製造システム |
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| JP6681764B2 (ja) * | 2016-03-29 | 2020-04-15 | 株式会社菊水製作所 | 成形品製造システム |
| EP3452220A4 (en) | 2016-05-02 | 2020-01-01 | Massachusetts Institute of Technology | RECONFIGURABLE MULTI-STAGE CHEMICAL SYNTHESIS SYSTEM AND COMPONENTS AND RELATED METHODS |
| JP6792001B2 (ja) * | 2016-07-01 | 2020-11-25 | メディシナル バイオコンバージェンス リサーチ センター | アミノアシルtRNA合成酵素関連タンパク質発現水準を利用した甲状腺瀘胞癌診断用組成物と診断マーカー検出方法 |
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| EP3684322B1 (en) * | 2017-09-21 | 2022-04-20 | F. Hoffmann-La Roche AG | Pharmaceutical manufacturing installation and method of manufacturing of a pharmaceutical product |
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| GB2578272B (en) * | 2018-07-10 | 2023-03-29 | Innopharma Res Limited | Apparatus and method for the production of solid dosage forms |
| ES2953293T3 (es) * | 2018-08-07 | 2023-11-10 | Norton Waterford Ltd | Aplicación de espectroscopia Raman para la fabricación de polvos para inhalación |
| US20220054359A1 (en) * | 2018-11-24 | 2022-02-24 | Scitech Centre | Continuous Production of Filled Capsules and Method Thereof |
| WO2020143864A1 (de) * | 2019-01-07 | 2020-07-16 | Nuuvera Deutschland GmbH | Vorrichtung für die tablettierung einer pulverförmigen, flüssigen, pastösen, verkapselten oder granularen wirkstoffzusammensetzung |
| JP7300708B2 (ja) * | 2019-04-01 | 2023-06-30 | 株式会社菊水製作所 | 粉体を用いる処理システム及びその制御方法 |
| EP3756640A1 (en) * | 2019-06-26 | 2020-12-30 | Fette Compacting GmbH | System and method for continuous production of solid dosage forms |
| DE102019218379A1 (de) * | 2019-11-27 | 2021-05-27 | Glatt Ingenieurtechnik Gesellschaft mit beschränkter Haftung | Modulare Anlage und Verfahren zur Herstellung von Arzneiformschüttgut |
| DE102020115777A1 (de) * | 2020-06-16 | 2021-12-16 | Fette Compacting Gmbh | Verfahren zur Produktverfolgung in einer Anlage |
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| EP4005663B1 (en) | 2020-11-26 | 2026-04-01 | Fette Compacting GmbH | Powder blender for a system for continuous processing of powder products |
| DE102021109944B4 (de) * | 2021-04-20 | 2023-02-23 | Fette Compacting Gmbh | System zum kontinuierlichen Verarbeiten von pulverförmigen Produkten |
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-
2009
- 2009-05-07 EP EP09786382.3A patent/EP2427166B1/en not_active Revoked
- 2009-05-07 ES ES09786382.3T patent/ES2441446T3/es active Active
- 2009-05-07 JP JP2012509101A patent/JP2012525895A/ja active Pending
- 2009-05-07 WO PCT/IB2009/051885 patent/WO2010128359A1/en not_active Ceased
- 2009-05-07 HR HRP20131155AT patent/HRP20131155T1/hr unknown
- 2009-05-07 US US13/319,023 patent/US9713575B2/en active Active
- 2009-05-07 BR BRPI0925048A patent/BRPI0925048B8/pt not_active IP Right Cessation
- 2009-05-07 CN CN2009801590959A patent/CN102438578A/zh active Pending
- 2009-05-07 DK DK09786382.3T patent/DK2427166T3/da active
- 2009-05-07 PT PT97863823T patent/PT2427166E/pt unknown
-
2016
- 2016-07-07 US US15/204,222 patent/US10016340B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010128359A1 (en) | 2010-11-11 |
| PT2427166E (pt) | 2014-01-20 |
| ES2441446T3 (es) | 2014-02-04 |
| US20160310365A1 (en) | 2016-10-27 |
| JP2012525895A (ja) | 2012-10-25 |
| US9713575B2 (en) | 2017-07-25 |
| EP2427166B1 (en) | 2013-10-16 |
| US20120061869A1 (en) | 2012-03-15 |
| DK2427166T3 (da) | 2014-01-27 |
| HRP20131155T1 (hr) | 2014-02-28 |
| CN102438578A (zh) | 2012-05-02 |
| BRPI0925048B8 (pt) | 2021-06-22 |
| US10016340B2 (en) | 2018-07-10 |
| EP2427166A1 (en) | 2012-03-14 |
| BRPI0925048B1 (pt) | 2019-07-09 |
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