BRPI1008359A2 - método para produzir partículas de medicamento de tamanho de partícula pequeno - Google Patents
método para produzir partículas de medicamento de tamanho de partícula pequenoInfo
- Publication number
- BRPI1008359A2 BRPI1008359A2 BRPI1008359A BRPI1008359A BRPI1008359A2 BR PI1008359 A2 BRPI1008359 A2 BR PI1008359A2 BR PI1008359 A BRPI1008359 A BR PI1008359A BR PI1008359 A BRPI1008359 A BR PI1008359A BR PI1008359 A2 BRPI1008359 A2 BR PI1008359A2
- Authority
- BR
- Brazil
- Prior art keywords
- particle size
- small particle
- producing small
- medicine particles
- size medicine
- Prior art date
Links
- 239000002245 particle Substances 0.000 title 2
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102009008478A DE102009008478A1 (de) | 2009-02-11 | 2009-02-11 | Vorrichtung und Verfahren zur Herstellung pharmazeutisch hochfeiner Partikel sowie zur Beschichtung solcher Partikel in Mikroreaktoren |
| DE102009008478.9 | 2009-02-11 | ||
| PCT/DE2010/075015 WO2010091683A2 (de) | 2009-02-11 | 2010-02-11 | Vorrichtung und verfahren zur herstellung pharmazeutisch hochfeiner partikel sowie zur beschichtung solcher partikel in mikroreaktoren |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI1008359A2 true BRPI1008359A2 (pt) | 2016-02-23 |
| BRPI1008359B1 BRPI1008359B1 (pt) | 2021-01-12 |
| BRPI1008359B8 BRPI1008359B8 (pt) | 2021-05-25 |
Family
ID=42338614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1008359A BRPI1008359B8 (pt) | 2009-02-11 | 2010-02-11 | método para produzir partículas de medicamento de tamanho de partícula pequeno |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8697131B2 (pt) |
| EP (1) | EP2395978B1 (pt) |
| JP (1) | JP5624059B2 (pt) |
| KR (1) | KR101515263B1 (pt) |
| CN (2) | CN105125502A (pt) |
| BR (1) | BRPI1008359B8 (pt) |
| CA (1) | CA2751625C (pt) |
| DE (1) | DE102009008478A1 (pt) |
| WO (1) | WO2010091683A2 (pt) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ602674A (en) | 2010-03-22 | 2013-10-25 | Mjr Pharmjet Gmbh | Method and device for producing microparticles or nanoparticles |
| US20120167410A1 (en) * | 2010-12-21 | 2012-07-05 | Basf Se | Spray drying techniques |
| CN103127889B (zh) * | 2011-11-29 | 2016-01-13 | 北京大学 | 制备功能纳米粒子的减压诱导微射流混合法及其应用 |
| BR112015024868A2 (pt) | 2013-03-28 | 2017-07-18 | Instillo Gmbh | método para produzir dispersões e matérias sólidas através de precipitação, coprecipitação e processo de auto-organização controlados e método para produzir dispersões e matérias sólidas através de precipitação controlada, coprecipitação e processo de auto-organização em um reator de microjato |
| US9468626B2 (en) | 2014-03-13 | 2016-10-18 | Chiesi Farmaceutici S.P.A. | Melatonin-based formulations for parenteral administration |
| CA2947486C (en) | 2014-05-19 | 2023-09-26 | The Medicines Company | Clevidipine nanoparticles and pharmaceutical compositions thereof |
| CN104226211B (zh) * | 2014-09-17 | 2018-08-10 | 天津春发生物科技集团有限公司 | 一种生物-喷雾干燥法制备香精微胶囊的方法 |
| DE202015100863U1 (de) | 2015-02-23 | 2016-05-30 | Care Connection Gmbh | Behälter zur Applikation einer Tannin-enthaltenden Deodorant- oder Antitranspirantzusammensetzung |
| DE202015100862U1 (de) | 2015-02-23 | 2016-05-30 | Care Connection Gmbh | Tannin-Nanopartikel enthaltende Deodorant- oder Antitranspirantzusammensetzung |
| EP3270891A1 (en) * | 2015-03-17 | 2018-01-24 | Leon-Nanodrugs GmbH | Nanoparticles comprising a stabilized boronic acid compound |
| DE102016101232A1 (de) | 2016-01-25 | 2017-07-27 | Instillo Gmbh | Verfahren zum Herstellen von Emulsionen |
| DE102017110292B4 (de) | 2017-05-11 | 2020-06-10 | Instillo Gmbh | Verfahren zum Herstellen von Reaktionsprodukten |
| WO2019166322A1 (en) | 2018-03-02 | 2019-09-06 | Chiesi Farmaceutici S.P.A. | A pharmaceutical formulation for intraduodenal administration comprising melevodopa and carbidopa |
| CN110385124B (zh) * | 2018-04-16 | 2021-01-26 | 浙江大学 | 一种通过分段反应制备MnOx-CeO2混合氧化物催化剂的方法 |
| US10912326B2 (en) | 2018-08-22 | 2021-02-09 | Rachelle MACSWEENEY | Nanoformulations containing encapsulted omega-3 fatty acids |
| DE102019112382A1 (de) | 2019-05-13 | 2020-11-19 | MyBiotech GmbH | Verwendung eines MikroJet-Reaktors zum Zellaufschluss |
| CA3141534A1 (en) | 2019-05-23 | 2020-11-26 | Helm Ag | Nanoparticles comprising enzalutamide |
| EP3795646A1 (de) | 2019-12-19 | 2021-03-24 | nanoSaar Lab GmbH | Farb- und füllstoffpasten unter verwendung anorganischer partikel mit beschichteter oberfläche als spacer |
| EP3915544A1 (en) | 2020-05-25 | 2021-12-01 | Leon-Nanodrugs GmbH | Method for producing a liposome dispersion |
| EP4008322B1 (de) | 2020-05-25 | 2024-11-27 | leon-nanodrugs GmbH | Lecithin-partikel im nanometer bereich als wirkstoffträger zur parenteralen verabreichung |
| EP3915673A1 (de) | 2020-05-25 | 2021-12-01 | Leon-Nanodrugs GmbH | Verfahren zur überprüfung der funktionsfähigkeit einer anlage zur herstellung von nanopartikeln durch gezielte fällung aus übersättigten lösungen |
| EP3915546A1 (de) * | 2020-05-25 | 2021-12-01 | Leon-Nanodrugs GmbH | Verwendung von säure als lösungsmittel für präzipitationen |
| AU2022270938A1 (en) | 2021-05-05 | 2023-11-02 | Leon-Nanodrugs Gmbh | Methods for producing nanoparticle dispersions |
| EP4163006B8 (en) | 2021-10-11 | 2024-03-20 | leon-nanodrugs GmbH | Methods for validating an apparatus for producing nanoparticles |
| EP4198105A1 (en) | 2021-12-16 | 2023-06-21 | Seaborough IP I B.V. | Microjet reactor based synthesis of nanophosphors |
| CN114669085B (zh) * | 2022-01-28 | 2024-05-31 | 南京宁源科生物技术有限公司 | 一种药用颗粒的有机溶剂去除装置 |
| WO2025228668A1 (en) | 2024-05-03 | 2025-11-06 | Leon-Nanodrugs Gmbh | Method for manufacturing lipid nanoparticles |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2078447T3 (es) | 1990-06-15 | 1995-12-16 | Merck & Co Inc | Un procedimiento de cristalizacion para mejorar la estructura y el tamaño de los cristales. |
| DE19617085A1 (de) * | 1996-04-29 | 1997-10-30 | Bayer Ag | Verfahren zur Herstellung von feinstteiligen Kristallisationsprodukten |
| GB9828721D0 (en) * | 1998-12-24 | 1999-02-17 | Glaxo Group Ltd | Novel apparatus and process |
| JP2002540930A (ja) * | 1999-04-08 | 2002-12-03 | ペント ベルント | 化学的プロセスおよび物理的プロセスを実施するための方法および装置 |
| YU34501A (sh) | 2000-05-26 | 2003-10-31 | Pfizer Products Inc. | Postupak reaktivne kristalizacije radi povećanja veličine čestica |
| NZ526608A (en) | 2000-12-22 | 2006-06-30 | Baxter Int | Method for preparing submicron particle suspensions |
| US6884436B2 (en) | 2000-12-22 | 2005-04-26 | Baxter International Inc. | Method for preparing submicron particle suspensions |
| DE10214031A1 (de) | 2002-03-27 | 2004-02-19 | Pharmatech Gmbh | Verfahren zur Herstellung und Anwendung von Mikro- und Nanoteilchen durch aufbauende Mikronisation |
| US7041144B2 (en) * | 2003-03-04 | 2006-05-09 | Five Star Technologies, Inc. | Hydrodynamic cavitation crystallization process |
| US20060151899A1 (en) | 2003-08-06 | 2006-07-13 | Akira Kato | Process for producing drug ultramicroparticle and apparatus therefor |
| TWI371274B (en) * | 2003-10-23 | 2012-09-01 | Bristol Myers Squibb Co | Process for making sterile aripiprazole of desired mean particle size |
| DE102005048201A1 (de) | 2004-10-11 | 2006-04-20 | Penth, Bernd, Dr. | Kontinuierliche Fällung von nanoskaligen Produkten in Mikroreaktoren |
| DE102005011786A1 (de) | 2005-03-11 | 2006-09-14 | Pharmasol Gmbh | Verfahren zur Herstellung ultrafeiner Submicron-Suspensionen |
| DE102005017777A1 (de) | 2005-04-13 | 2006-10-19 | Pharmasol Gmbh | Verfahren zur schonenden Herstellung von hochfeinen Partikelsuspensionen |
| DE102005048021B3 (de) | 2005-10-06 | 2007-04-12 | Abb Patent Gmbh | Lokal bedienbares Automatisierungsgerät |
| DE102005053862A1 (de) | 2005-11-04 | 2007-05-10 | Pharmasol Gmbh | Verfahren und Vorrichtung zur Herstellung hochfeiner Partikel sowie zur Beschichtung solcher Partikel |
-
2009
- 2009-02-11 DE DE102009008478A patent/DE102009008478A1/de not_active Withdrawn
-
2010
- 2010-02-11 JP JP2011548532A patent/JP5624059B2/ja active Active
- 2010-02-11 CN CN201510359931.5A patent/CN105125502A/zh active Pending
- 2010-02-11 KR KR1020117021104A patent/KR101515263B1/ko active Active
- 2010-02-11 CA CA2751625A patent/CA2751625C/en active Active
- 2010-02-11 CN CN2010800073233A patent/CN102316853A/zh active Pending
- 2010-02-11 WO PCT/DE2010/075015 patent/WO2010091683A2/de not_active Ceased
- 2010-02-11 EP EP10710995.1A patent/EP2395978B1/de active Active
- 2010-02-11 US US13/138,389 patent/US8697131B2/en active Active
- 2010-02-11 BR BRPI1008359A patent/BRPI1008359B8/pt active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP2395978B1 (de) | 2015-05-27 |
| CA2751625A1 (en) | 2010-08-19 |
| CN102316853A (zh) | 2012-01-11 |
| DE102009008478A1 (de) | 2010-08-19 |
| CN105125502A (zh) | 2015-12-09 |
| BRPI1008359B1 (pt) | 2021-01-12 |
| KR101515263B1 (ko) | 2015-04-24 |
| KR20110118714A (ko) | 2011-10-31 |
| US20110294770A1 (en) | 2011-12-01 |
| CA2751625C (en) | 2014-10-14 |
| EP2395978A2 (de) | 2011-12-21 |
| JP5624059B2 (ja) | 2014-11-12 |
| US8697131B2 (en) | 2014-04-15 |
| JP2012517403A (ja) | 2012-08-02 |
| WO2010091683A2 (de) | 2010-08-19 |
| WO2010091683A3 (de) | 2010-10-21 |
| BRPI1008359B8 (pt) | 2021-05-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI1008359A2 (pt) | método para produzir partículas de medicamento de tamanho de partícula pequeno | |
| EP2545104A4 (en) | PARTICLES AND METHOD FOR THE PRODUCTION THEREOF | |
| CO6930351A2 (es) | Línea de proceso para la producción de particulas criodesecadas | |
| CO6930352A2 (es) | Línea de proceso para la producción de partículas criodesecadas | |
| PL2736837T3 (pl) | Sposób produkcji nanodrutów krzemowych | |
| SG11201400744XA (en) | Self-assembled nano-structure particle and method for preparing | |
| ZA201403625B (en) | Method for manufacturing spheroidal alumina particles | |
| SG2014004741A (en) | Particle breakup size apparatus | |
| BR112013008062A2 (pt) | métodos para produzir partículas de réplicon de bunyavírus | |
| PT2686026T (pt) | Partículas compósitas microestruturadas | |
| GB201109319D0 (en) | Fine particles | |
| ZA201206091B (en) | Methods for producing photosensitive microparticles | |
| EP2699670A4 (en) | PARTICLES SYNTHETIZED FROM CELLS | |
| ZA201309469B (en) | Process for producing inorganic particulate material | |
| EP2610338A4 (en) | PROCESS FOR PRODUCTION OF SUBSTANCE | |
| EP2707480A4 (en) | PSEUDOVIRAL PARTICLES (VLPs) AND PREPARATION METHOD THEREOF | |
| SG11201400287XA (en) | Methods for producing biocompatible materials | |
| EP2919898A4 (en) | PROCESS FOR PRODUCTION OF PARTICLES AND APPARATUS THEREFOR | |
| SMT202100198T1 (it) | Metodo e apparecchio per la preparazione di particelle di idrossodo di calcio | |
| SI2739725T1 (sl) | Postopek za čiščenje od virusov-podobnih delcev | |
| PT2570120T (pt) | Partículas revestidas e processo de produção de partículas revestidas | |
| ZA201404277B (en) | Process for making magnolol and derivatives thereof | |
| PT2550305T (pt) | Processo contínuo para preparar partículas de polifluoroacrilato | |
| EP2835686A4 (en) | FINE ELECTRETIC PARTICLES AND METHOD FOR THE PRODUCTION THEREOF | |
| SG11201401251TA (en) | Slurry and method for producing slurry |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25D | Requested change of name of applicant approved |
Owner name: INSTILLO GMBH (DE) |
|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 12/01/2021, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 11/02/2010 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |