BRPI1008562A2 - derivados de 3-benzofuranil-indol-2-ona-3-acetamino piperazinas substituídos, o respectivo preparo e a respectiva aplicação em terapêutica - Google Patents
derivados de 3-benzofuranil-indol-2-ona-3-acetamino piperazinas substituídos, o respectivo preparo e a respectiva aplicação em terapêuticaInfo
- Publication number
- BRPI1008562A2 BRPI1008562A2 BRPI1008562A BRPI1008562A BRPI1008562A2 BR PI1008562 A2 BRPI1008562 A2 BR PI1008562A2 BR PI1008562 A BRPI1008562 A BR PI1008562A BR PI1008562 A BRPI1008562 A BR PI1008562A BR PI1008562 A2 BRPI1008562 A2 BR PI1008562A2
- Authority
- BR
- Brazil
- Prior art keywords
- acetamino
- indol
- benzofuranyl
- substituted
- preparation
- Prior art date
Links
- IFBARXMKIVQPAL-UHFFFAOYSA-N 3-(1-benzofuran-2-yl)indol-2-one;n-piperazin-2-ylacetamide Chemical class CC(=O)NC1CNCCN1.C1=CC=C2OC(C3=C4C=CC=CC4=NC3=O)=CC2=C1 IFBARXMKIVQPAL-UHFFFAOYSA-N 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0900620A FR2941946B1 (fr) | 2009-02-12 | 2009-02-12 | Derives de 3-benzofuranyl-indol-2-one-3-acetamidopiperazines substitues, leur preparation et leur application en therapeutique |
| PCT/FR2010/050206 WO2010092288A1 (fr) | 2009-02-12 | 2010-02-09 | Derives de 3-benzofuranyl-indol-2-one-3-acetamidopiperazines substitues, leur preparation et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1008562A2 true BRPI1008562A2 (pt) | 2017-06-06 |
Family
ID=40756656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1008562A BRPI1008562A2 (pt) | 2009-02-12 | 2010-02-09 | derivados de 3-benzofuranil-indol-2-ona-3-acetamino piperazinas substituídos, o respectivo preparo e a respectiva aplicação em terapêutica |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20110312972A1 (pt) |
| EP (1) | EP2396319B1 (pt) |
| JP (1) | JP5694958B2 (pt) |
| KR (1) | KR20110118157A (pt) |
| CN (1) | CN102361864B (pt) |
| AR (1) | AR075398A1 (pt) |
| AU (1) | AU2010212704B2 (pt) |
| BR (1) | BRPI1008562A2 (pt) |
| CA (1) | CA2752198C (pt) |
| FR (1) | FR2941946B1 (pt) |
| IL (1) | IL214544A0 (pt) |
| JO (1) | JO2851B1 (pt) |
| MX (1) | MX2011008546A (pt) |
| MY (1) | MY152069A (pt) |
| RU (1) | RU2542980C2 (pt) |
| SG (1) | SG173623A1 (pt) |
| TW (1) | TWI461421B (pt) |
| UY (1) | UY32448A (pt) |
| WO (1) | WO2010092288A1 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2941946B1 (fr) | 2009-02-12 | 2011-03-25 | Sanofi Aventis | Derives de 3-benzofuranyl-indol-2-one-3-acetamidopiperazines substitues, leur preparation et leur application en therapeutique |
| FR2941947B1 (fr) * | 2009-02-12 | 2011-03-25 | Sanofi Aventis | Derives de 3-benzofuranyl-indol-2-one subtitues en 3, leur preparation et leur application en therapeutique |
| US20110105389A1 (en) | 2009-10-30 | 2011-05-05 | Hoveyda Hamid R | Macrocyclic Ghrelin Receptor Antagonists and Inverse Agonists and Methods of Using the Same |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2714378B1 (fr) | 1993-12-24 | 1996-03-15 | Sanofi Sa | Dérivés de l'indol-2-one substitués en 3 par un groupe azoté, leur préparation, les compositions pharmaceutiques en contenant. |
| CN1161333C (zh) * | 1998-08-20 | 2004-08-11 | 住友制药株式会社 | 作为生长激素释放剂的2-羟基吲哚衍生物 |
| NZ517900A (en) * | 1999-08-23 | 2003-08-29 | Solvay Pharm Bv | Phenylpiperazines useful as serotonin reuptake inhibitors |
| EP1303269B1 (en) * | 2000-06-29 | 2005-12-07 | NeuroSearch A/S | Use of 3-substituted oxindole derivatives as kcnq potassium channel modulators |
| WO2002060878A1 (fr) * | 2001-01-30 | 2002-08-08 | Sumitomo Pharmaceuticals Co., Ltd. | Derives de benzimidazolidinone |
| FR2827604B1 (fr) | 2001-07-17 | 2003-09-19 | Sanofi Synthelabo | Nouveaux derives de 1-phenylsulfonyl-1,3-dihydro-2h-indol-2- one, un procede pour leur preparation et les compositions pharmaceutiques en contenant |
| US20050070718A1 (en) * | 2003-09-30 | 2005-03-31 | Abbott Gmbh & Co. Kg | Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them |
| JPWO2005035498A1 (ja) * | 2003-10-08 | 2006-12-21 | 住友製薬株式会社 | 含窒素二環性化合物の摂食調節剤としての用途 |
| TWI391387B (zh) * | 2004-05-12 | 2013-04-01 | Eisai R&D Man Co Ltd | 具有哌啶環之吲哚衍生物 |
| JPWO2007032371A1 (ja) * | 2005-09-14 | 2009-03-19 | 大日本住友製薬株式会社 | 摂食調節剤としてのオキシインドール誘導体 |
| FR2920023B1 (fr) * | 2007-08-16 | 2013-02-08 | Sanofi Aventis | Derives de l'indol-2-one disubstitues en 3, leur preparation et leur application en therapeutique |
| FR2941946B1 (fr) | 2009-02-12 | 2011-03-25 | Sanofi Aventis | Derives de 3-benzofuranyl-indol-2-one-3-acetamidopiperazines substitues, leur preparation et leur application en therapeutique |
| FR2941947B1 (fr) * | 2009-02-12 | 2011-03-25 | Sanofi Aventis | Derives de 3-benzofuranyl-indol-2-one subtitues en 3, leur preparation et leur application en therapeutique |
-
2009
- 2009-02-12 FR FR0900620A patent/FR2941946B1/fr not_active Expired - Fee Related
-
2010
- 2010-02-09 KR KR1020117020970A patent/KR20110118157A/ko not_active Withdrawn
- 2010-02-09 US US13/201,141 patent/US20110312972A1/en not_active Abandoned
- 2010-02-09 MX MX2011008546A patent/MX2011008546A/es active IP Right Grant
- 2010-02-09 SG SG2011057551A patent/SG173623A1/en unknown
- 2010-02-09 JP JP2011549642A patent/JP5694958B2/ja not_active Expired - Fee Related
- 2010-02-09 EP EP10708306.5A patent/EP2396319B1/fr active Active
- 2010-02-09 CN CN201080012865.XA patent/CN102361864B/zh not_active Expired - Fee Related
- 2010-02-09 BR BRPI1008562A patent/BRPI1008562A2/pt not_active Application Discontinuation
- 2010-02-09 WO PCT/FR2010/050206 patent/WO2010092288A1/fr not_active Ceased
- 2010-02-09 AU AU2010212704A patent/AU2010212704B2/en not_active Ceased
- 2010-02-09 MY MYPI2011003748 patent/MY152069A/en unknown
- 2010-02-09 RU RU2011137408/04A patent/RU2542980C2/ru not_active IP Right Cessation
- 2010-02-09 CA CA2752198A patent/CA2752198C/fr not_active Expired - Fee Related
- 2010-02-10 JO JO201042A patent/JO2851B1/en active
- 2010-02-11 AR ARP100100378A patent/AR075398A1/es unknown
- 2010-02-11 TW TW099104420A patent/TWI461421B/zh not_active IP Right Cessation
- 2010-02-12 UY UY0001032448A patent/UY32448A/es not_active Application Discontinuation
-
2011
- 2011-08-09 IL IL214544A patent/IL214544A0/en unknown
-
2016
- 2016-11-10 US US15/348,834 patent/US9889130B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| TWI461421B (zh) | 2014-11-21 |
| UY32448A (es) | 2010-09-30 |
| JP5694958B2 (ja) | 2015-04-01 |
| MX2011008546A (es) | 2011-11-18 |
| AU2010212704B2 (en) | 2015-11-12 |
| KR20110118157A (ko) | 2011-10-28 |
| FR2941946A1 (fr) | 2010-08-13 |
| EP2396319B1 (fr) | 2013-07-17 |
| MY152069A (en) | 2014-08-15 |
| CN102361864A (zh) | 2012-02-22 |
| AR075398A1 (es) | 2011-03-30 |
| RU2542980C2 (ru) | 2015-02-27 |
| JO2851B1 (en) | 2015-03-15 |
| CN102361864B (zh) | 2015-11-25 |
| US9889130B2 (en) | 2018-02-13 |
| AU2010212704A1 (en) | 2011-09-01 |
| US20170119761A1 (en) | 2017-05-04 |
| US20110312972A1 (en) | 2011-12-22 |
| CA2752198A1 (fr) | 2010-08-19 |
| TW201041877A (en) | 2010-12-01 |
| RU2011137408A (ru) | 2013-03-20 |
| JP2012517460A (ja) | 2012-08-02 |
| IL214544A0 (en) | 2011-09-27 |
| EP2396319A1 (fr) | 2011-12-21 |
| CA2752198C (fr) | 2017-05-30 |
| HK1164861A1 (en) | 2012-09-28 |
| WO2010092288A1 (fr) | 2010-08-19 |
| SG173623A1 (en) | 2011-09-29 |
| FR2941946B1 (fr) | 2011-03-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |