DK2397480T3 - Diazepindionderivat - Google Patents
DiazepindionderivatInfo
- Publication number
- DK2397480T3 DK2397480T3 DK10741334.6T DK10741334T DK2397480T3 DK 2397480 T3 DK2397480 T3 DK 2397480T3 DK 10741334 T DK10741334 T DK 10741334T DK 2397480 T3 DK2397480 T3 DK 2397480T3
- Authority
- DK
- Denmark
- Prior art keywords
- diazepindion
- derivatives
- diazepindion derivatives
- Prior art date
Links
- RTXTUGWLUYJQCG-UHFFFAOYSA-N 1h-diazepine-6,7-dione Chemical class O=C1C=CC=NNC1=O RTXTUGWLUYJQCG-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009032705 | 2009-02-16 | ||
| PCT/JP2010/052571 WO2010093061A1 (ja) | 2009-02-16 | 2010-02-15 | ジアゼピンジオン誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2397480T3 true DK2397480T3 (da) | 2013-09-02 |
Family
ID=42561898
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10741334.6T DK2397480T3 (da) | 2009-02-16 | 2010-02-15 | Diazepindionderivat |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8470814B2 (da) |
| EP (1) | EP2397480B1 (da) |
| JP (1) | JP5592278B2 (da) |
| KR (1) | KR101727761B1 (da) |
| CN (1) | CN102395577B (da) |
| CA (1) | CA2789641C (da) |
| DK (1) | DK2397480T3 (da) |
| ES (1) | ES2432265T3 (da) |
| PL (1) | PL2397480T3 (da) |
| WO (1) | WO2010093061A1 (da) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012008478A1 (ja) * | 2010-07-13 | 2012-01-19 | 日本ケミファ株式会社 | Ｐ２ｘ４受容体拮抗剤 |
| WO2012014910A1 (ja) * | 2010-07-29 | 2012-02-02 | 日本ケミファ株式会社 | Ｐ２ｘ４受容体拮抗剤 |
| US9115123B2 (en) * | 2010-11-05 | 2015-08-25 | Kyushu University | Preventive or therapeutic agent for pain associated with herpes zoster in acute phase |
| ES2653244T3 (es) * | 2011-05-25 | 2018-02-06 | Nippon Chemiphar Co., Ltd. | Agente profiláctico o terapéutico para dolor neuropático asociado al Síndrome de Guillain-Barré |
| DK2803662T3 (da) | 2012-01-13 | 2017-05-01 | Nippon Chemiphar Co | P2X4-receptorantagonist |
| US10150744B2 (en) | 2013-07-12 | 2018-12-11 | Nippon Chemiphar Co., Ltd | P2X4 receptor antagonist |
| CA2921203C (en) | 2013-07-12 | 2021-07-27 | Nippon Chemiphar Co., Ltd. | Diazepinedione derivatives and compositions thereof useful as p2x4 receptor antagonist |
| BR112016025450A2 (pt) | 2014-05-02 | 2017-12-12 | Medimmune Ltd | moduladores de canais de íons e usos dos mesmos |
| CN109414503A (zh) * | 2016-04-28 | 2019-03-01 | 日本化学药品株式会社 | 用于多发性硬化症的治疗的医药品 |
| US10695355B2 (en) * | 2017-03-30 | 2020-06-30 | University Of Connecticut | Methods for pharmacologic treatment of stroke |
| JP7374882B2 (ja) * | 2018-03-14 | 2023-11-07 | 日本ケミファ株式会社 | 咳嗽の治療のための医薬 |
| EP3848051A4 (en) * | 2018-09-03 | 2022-06-08 | Nippon Chemiphar Co., Ltd. | DRUG TARGETING DIABETIC PERIPHERAL NEUROPATHY |
| JP2022163241A (ja) * | 2019-09-13 | 2022-10-26 | 日本ケミファ株式会社 | Ｐ２ｘ４受容体拮抗剤 |
| AU2020439775A1 (en) * | 2020-03-30 | 2022-11-03 | Nippon Chemiphar Co., Ltd. | Medicament for use in preventing or treating irritable bowel syndrome or inflammatory bowel disease |
| AU2021301158A1 (en) * | 2020-06-30 | 2022-12-15 | Bayer Aktiengesellschaft | Use of N-phenylacetamides having P2X4 receptor antagonistic activity for treating certain ocular disorders |
| JP7621619B2 (ja) | 2020-08-03 | 2025-01-27 | 日本ケミファ株式会社 | アレルギー反応に伴う症状の予防若しくは抑制又は治療用の医薬組成物 |
| IT202100025124A1 (it) | 2021-09-30 | 2023-03-30 | Univ Degli Studi Di Firenze | Medicamento per uso nel prevenire o trattare il dolore nocicettivo e/o viscerale |
| EP4410310A4 (en) | 2021-09-30 | 2025-10-22 | Nippon Chemiphar Co | PROPHYLACTIC OR THERAPEUTIC AGENT FOR RESPIRATORY DISEASES |
| JP2025041993A (ja) * | 2022-02-17 | 2025-03-27 | 国立大学法人鳥取大学 | 子宮内膜症又は子宮腺筋症の予防又は治療剤 |
| AU2023244778A1 (en) | 2022-03-31 | 2024-10-17 | Nippon Chemiphar Co., Ltd. | Pharmaceutical composition for preventing or suppressing or treating symptoms accompanying pseudo-allergic reactions |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4969105A (en) | 1988-05-02 | 1990-11-06 | Ingersoll-Rand Company | Gasket compression control method having tension-related feedback |
| DE10312969A1 (de) * | 2003-03-24 | 2004-10-07 | Bayer Healthcare Ag | Benzofuro-1,4-diazepin-2-on-Derivate |
| CA2444161A1 (en) | 2003-10-01 | 2005-04-01 | Japan Health Sciences Foundation | A screening method of drug for treatment of neuropathic pain |
| JP2009057281A (ja) | 2005-12-19 | 2009-03-19 | Nippon Chemiphar Co Ltd | Ｐ２ｘ４受容体拮抗剤 |
| JP2009062278A (ja) * | 2005-12-29 | 2009-03-26 | Nippon Chemiphar Co Ltd | Ｐ２ｘ４受容体拮抗剤 |
| JPWO2008023847A1 (ja) | 2006-08-25 | 2010-01-14 | 日本ケミファ株式会社 | Ｐ２ｘ４受容体拮抗剤 |
-
2010
- 2010-02-15 DK DK10741334.6T patent/DK2397480T3/da active
- 2010-02-15 KR KR1020117021273A patent/KR101727761B1/ko not_active Expired - Fee Related
- 2010-02-15 ES ES10741334T patent/ES2432265T3/es active Active
- 2010-02-15 EP EP10741334.6A patent/EP2397480B1/en active Active
- 2010-02-15 WO PCT/JP2010/052571 patent/WO2010093061A1/ja not_active Ceased
- 2010-02-15 US US13/148,728 patent/US8470814B2/en not_active Expired - Fee Related
- 2010-02-15 CA CA2789641A patent/CA2789641C/en active Active
- 2010-02-15 JP JP2010550574A patent/JP5592278B2/ja active Active
- 2010-02-15 PL PL10741334T patent/PL2397480T3/pl unknown
- 2010-02-15 CN CN201080017261.4A patent/CN102395577B/zh not_active Expired - Fee Related
-
2013
- 2013-06-19 US US13/921,382 patent/US8778933B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20130281441A1 (en) | 2013-10-24 |
| EP2397480A4 (en) | 2012-07-25 |
| KR20110120939A (ko) | 2011-11-04 |
| PL2397480T3 (pl) | 2014-01-31 |
| WO2010093061A1 (ja) | 2010-08-19 |
| CN102395577A (zh) | 2012-03-28 |
| CN102395577B (zh) | 2014-04-23 |
| JP5592278B2 (ja) | 2014-09-17 |
| CA2789641A1 (en) | 2010-08-19 |
| US8778933B2 (en) | 2014-07-15 |
| US8470814B2 (en) | 2013-06-25 |
| KR101727761B1 (ko) | 2017-04-17 |
| EP2397480A1 (en) | 2011-12-21 |
| CA2789641C (en) | 2018-03-13 |
| EP2397480B1 (en) | 2013-08-14 |
| ES2432265T3 (es) | 2013-12-02 |
| JPWO2010093061A1 (ja) | 2012-08-16 |
| US20110319610A1 (en) | 2011-12-29 |
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