DK2397480T3 - Diazepindionderivat - Google Patents

Diazepindionderivat

Info

Publication number
DK2397480T3
DK2397480T3 DK10741334.6T DK10741334T DK2397480T3 DK 2397480 T3 DK2397480 T3 DK 2397480T3 DK 10741334 T DK10741334 T DK 10741334T DK 2397480 T3 DK2397480 T3 DK 2397480T3
Authority
DK
Denmark
Prior art keywords
diazepindion
derivatives
diazepindion derivatives
Prior art date
Application number
DK10741334.6T
Other languages
English (en)
Inventor
Shogo Sakuma
Toshihiro Takahashi
Masatoshi Ushioda
Toshiyasu Imai
Kazuhide Inoue
Original Assignee
Nippon Chemiphar Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co filed Critical Nippon Chemiphar Co
Application granted granted Critical
Publication of DK2397480T3 publication Critical patent/DK2397480T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK10741334.6T 2009-02-16 2010-02-15 Diazepindionderivat DK2397480T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009032705 2009-02-16
PCT/JP2010/052571 WO2010093061A1 (ja) 2009-02-16 2010-02-15 ジアゼピンジオン誘導体

Publications (1)

Publication Number Publication Date
DK2397480T3 true DK2397480T3 (da) 2013-09-02

Family

ID=42561898

Family Applications (1)

Application Number Title Priority Date Filing Date
DK10741334.6T DK2397480T3 (da) 2009-02-16 2010-02-15 Diazepindionderivat

Country Status (10)

Country Link
US (2) US8470814B2 (da)
EP (1) EP2397480B1 (da)
JP (1) JP5592278B2 (da)
KR (1) KR101727761B1 (da)
CN (1) CN102395577B (da)
CA (1) CA2789641C (da)
DK (1) DK2397480T3 (da)
ES (1) ES2432265T3 (da)
PL (1) PL2397480T3 (da)
WO (1) WO2010093061A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103080094B (zh) * 2010-07-13 2015-06-24 日本化学医药株式会社 P2x4受体拮抗剂
CA2809113C (en) * 2010-07-29 2019-01-15 Nippon Chemiphar Co., Ltd. P2x4 receptor antagonist
EP2636414A4 (en) * 2010-11-05 2014-04-02 Univ Kyushu Preventive or therapeutic agent for pain associated with herpes zoster in acute phase
ES2653244T3 (es) * 2011-05-25 2018-02-06 Nippon Chemiphar Co., Ltd. Agente profiláctico o terapéutico para dolor neuropático asociado al Síndrome de Guillain-Barré
WO2013105608A1 (ja) 2012-01-13 2013-07-18 日本ケミファ株式会社 P2x4受容体拮抗剤
JP6357475B2 (ja) * 2013-07-12 2018-07-11 日本ケミファ株式会社 P2x4受容体拮抗剤
EP3564217B1 (en) * 2013-07-12 2021-01-27 Nippon Chemiphar Co., Ltd. P2x4 receptor antagonist
ES2899754T3 (es) 2014-05-02 2022-03-14 Medimmune Ltd Moduladores de canales iónicos y usos de los mismos
CN122272595A (zh) * 2016-04-28 2026-06-26 日本化学药品株式会社 用于多发性硬化症的治疗的医药品
US10695355B2 (en) * 2017-03-30 2020-06-30 University Of Connecticut Methods for pharmacologic treatment of stroke
JP7374882B2 (ja) * 2018-03-14 2023-11-07 日本ケミファ株式会社 咳嗽の治療のための医薬
JP7541483B2 (ja) 2018-09-03 2024-08-28 日本ケミファ株式会社 糖尿病性末梢神経障害のための医薬
JP2022163241A (ja) * 2019-09-13 2022-10-26 日本ケミファ株式会社 P2x4受容体拮抗剤
EP4129296B1 (en) * 2020-03-30 2025-10-22 Nippon Chemiphar Co., Ltd. Drug for prevention or treatment of irritable bowel syndrome or inflammatory bowel disease
WO2022002860A1 (en) 2020-06-30 2022-01-06 Bayer Aktiengesellschaft Use of n-phenylacetamides having p2x4 receptor antagonistic activity for treating certain ocular disorders
CN116437928B (zh) 2020-08-03 2026-06-19 日本化学药品株式会社 用于预防、抑制或治疗伴随着过敏反应的症状的医药组合物
IT202100025124A1 (it) 2021-09-30 2023-03-30 Univ Degli Studi Di Firenze Medicamento per uso nel prevenire o trattare il dolore nocicettivo e/o viscerale
EP4410310A4 (en) 2021-09-30 2025-10-22 Nippon Chemiphar Co PROPHYLACTIC OR THERAPEUTIC AGENT FOR RESPIRATORY DISEASES
JP2025041993A (ja) * 2022-02-17 2025-03-27 国立大学法人鳥取大学 子宮内膜症又は子宮腺筋症の予防又は治療剤
AU2023244778A1 (en) 2022-03-31 2024-10-17 Nippon Chemiphar Co., Ltd. Pharmaceutical composition for preventing or suppressing or treating symptoms accompanying pseudo-allergic reactions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4969105A (en) 1988-05-02 1990-11-06 Ingersoll-Rand Company Gasket compression control method having tension-related feedback
DE10312969A1 (de) * 2003-03-24 2004-10-07 Bayer Healthcare Ag Benzofuro-1,4-diazepin-2-on-Derivate
US20050074819A1 (en) 2003-10-01 2005-04-07 Japan Health Sciences Foundation Screening method of drug for treatment of neuropathic pain
JP2009057281A (ja) 2005-12-19 2009-03-19 Nippon Chemiphar Co Ltd P2x4受容体拮抗剤
JP2009062278A (ja) 2005-12-29 2009-03-26 Nippon Chemiphar Co Ltd P2x4受容体拮抗剤
US20100256123A1 (en) 2006-08-25 2010-10-07 Nippon Chemiphar Co., Ltd. P2x4 receptor antagonist

Also Published As

Publication number Publication date
JP5592278B2 (ja) 2014-09-17
US20130281441A1 (en) 2013-10-24
KR101727761B1 (ko) 2017-04-17
CA2789641C (en) 2018-03-13
PL2397480T3 (pl) 2014-01-31
US8470814B2 (en) 2013-06-25
EP2397480A1 (en) 2011-12-21
CN102395577B (zh) 2014-04-23
CN102395577A (zh) 2012-03-28
WO2010093061A1 (ja) 2010-08-19
EP2397480A4 (en) 2012-07-25
KR20110120939A (ko) 2011-11-04
CA2789641A1 (en) 2010-08-19
EP2397480B1 (en) 2013-08-14
ES2432265T3 (es) 2013-12-02
JPWO2010093061A1 (ja) 2012-08-16
US8778933B2 (en) 2014-07-15
US20110319610A1 (en) 2011-12-29

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