BRPI1008660A2 - derivados de n-[(2-aza-biciclo[2.1.1] hex-1-il)-aril-metil]benzamida, sua preparação e sua aplicação em teraêutica - Google Patents

derivados de n-[(2-aza-biciclo[2.1.1] hex-1-il)-aril-metil]benzamida, sua preparação e sua aplicação em teraêutica

Info

Publication number
BRPI1008660A2
BRPI1008660A2 BRPI1008660A BRPI1008660A BRPI1008660A2 BR PI1008660 A2 BRPI1008660 A2 BR PI1008660A2 BR PI1008660 A BRPI1008660 A BR PI1008660A BR PI1008660 A BRPI1008660 A BR PI1008660A BR PI1008660 A2 BRPI1008660 A2 BR PI1008660A2
Authority
BR
Brazil
Prior art keywords
arylmethyl
aza
bicyclo
hex
therapeutics
Prior art date
Application number
BRPI1008660A
Other languages
English (en)
Inventor
Abdel-Kader Mafroud
Geneviéve Estenne-Bouhtou
Gihad Dargazanli
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of BRPI1008660A2 publication Critical patent/BRPI1008660A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
BRPI1008660A 2009-02-10 2010-02-09 derivados de n-[(2-aza-biciclo[2.1.1] hex-1-il)-aril-metil]benzamida, sua preparação e sua aplicação em teraêutica BRPI1008660A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0900578A FR2941953B1 (fr) 2009-02-10 2009-02-10 Derives de n-°(2-aza-bicyclo°2.1.1!hex-1-yl)-benzamide, leur preparation et leur application en therapeutique
PCT/FR2010/050203 WO2010092286A1 (fr) 2009-02-10 2010-02-09 Derives de n-[(2-aza-bicyclo[2.1.1]hex-1-yl]-aryl-methyl]-benzamide, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
BRPI1008660A2 true BRPI1008660A2 (pt) 2016-03-08

Family

ID=40935627

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1008660A BRPI1008660A2 (pt) 2009-02-10 2010-02-09 derivados de n-[(2-aza-biciclo[2.1.1] hex-1-il)-aril-metil]benzamida, sua preparação e sua aplicação em teraêutica

Country Status (17)

Country Link
US (1) US20120071536A1 (pt)
EP (1) EP2396334A1 (pt)
JP (1) JP2012517411A (pt)
KR (1) KR20110118812A (pt)
CN (1) CN102388049A (pt)
AR (1) AR075379A1 (pt)
AU (1) AU2010212702A1 (pt)
BR (1) BRPI1008660A2 (pt)
CA (1) CA2751863A1 (pt)
FR (1) FR2941953B1 (pt)
IL (1) IL214490A0 (pt)
MX (1) MX2011008447A (pt)
RU (1) RU2011137463A (pt)
SG (1) SG173606A1 (pt)
TW (1) TW201036979A (pt)
UY (1) UY32428A (pt)
WO (1) WO2010092286A1 (pt)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2861070B1 (fr) * 2003-10-17 2006-01-06 Sanofi Synthelabo Derives de n-[phenyl(pyrrolidin-2-yl)methyl]benzamide et n-[(azepan-2-yl)phenylmethyl]benzamide, leur preparation et leur application en therapeutique
FR2861076B1 (fr) * 2003-10-17 2006-01-06 Sanofi Synthelabo Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique
WO2005058317A1 (en) * 2003-12-18 2005-06-30 Glaxo Group Limited Glycine transporter-1 inhibirors
AU2006309050B2 (en) * 2005-10-28 2012-08-16 Merck Sharp & Dohme Corp. Piperidine glycine transporter inhibitors
WO2009013535A1 (en) * 2007-07-23 2009-01-29 Astrazeneca Ab 2-azabicyclo(2.2.2)octane derivatives as modulators of the glycine transporter i receptor

Also Published As

Publication number Publication date
FR2941953A1 (fr) 2010-08-13
TW201036979A (en) 2010-10-16
RU2011137463A (ru) 2013-03-20
FR2941953B1 (fr) 2011-04-08
JP2012517411A (ja) 2012-08-02
US20120071536A1 (en) 2012-03-22
EP2396334A1 (fr) 2011-12-21
KR20110118812A (ko) 2011-11-01
CA2751863A1 (fr) 2010-08-19
AR075379A1 (es) 2011-03-30
WO2010092286A1 (fr) 2010-08-19
AU2010212702A1 (en) 2011-09-01
UY32428A (es) 2010-09-30
CN102388049A (zh) 2012-03-21
IL214490A0 (en) 2011-09-27
MX2011008447A (es) 2011-11-29
SG173606A1 (en) 2011-09-29

Similar Documents

Publication Publication Date Title
NO20091424L (no) Substituerte amider, fremgangsmåte for fremstilling derav og anvendelse derav
NO20091426L (no) Substituerte amider, fremgangsmåte for fremstilling derav og anvendelse derav
NO2017002I1 (no) Cobicistat eller farmasøytisk akseptabelt salt derav og atazanavir eller farmasøytisk akseptabelt salt derav, spesielt atazanavirsulfat
IT1392423B1 (it) Struttura di guanto, in particolare da motociclismo, e metodo per la sua realizzazione.
BRPI1015967A2 (pt) "unidade de dobradiça, e, peça de mobília."
DK2254927T3 (da) Fugte- og dispergeringsmidler, disses fremstilling og anvendelse
BRPI1014914A2 (pt) Composição contendo trehalulose, sua preparação e uso
BRPI0818144A2 (pt) Produção de termolisin e variantes deste, e uso em detergentes líquidos
BRPI0905663A2 (pt) "emulsão estável, processo de preparação da emulsão estável e uso emulsão"
FR2884516B1 (fr) Antagonistes npy, preparation et utilisations
BRPI0912807A2 (pt) produto de aço inoxidável, uso do produto e método de sua fabricação
UY33079A (es) Derivados de difenil -pirazolopiridinas, su preparación y su aplicación en terapeutica
BRPI0915552A2 (pt) derivados de ciclosporina, seu uso e sua composição farmacêutica
BRPI0814931A2 (pt) Composto com atividade contra hcv, sua composição e seu uso
BRPI0909828A2 (pt) corantes dispersos de azopiridona, sua preparação e uso
BRPI0822223A2 (pt) Derivados de imidazo [1,2-alfa] piridina-2-carboxamidas, sua preparação e sua aplicação em terapêutica
BRPI1011822A2 (pt) "compostos de 3-substituída-8-substituída-3h-imidazo[5,1-d][1,2,3,5-tetrazin-4-ona e sua aplicação"
BRPI0907486A2 (pt) Triazolpiridazinas como inibidores de par1, sua produção e uso como medicamentos
IL193384A0 (en) Substituted prolinamides, their preparation and their use as pharmaceuticals
BRPI1008147A2 (pt) composição de xampu concentrado e xampu centrado
IL195207A0 (en) Aryl-and heteroaryl-ethyl-acylguanidine derivatives, their preparation and their application in therapeutics
DK2310383T3 (da) 2-oxo-alkyl-1-piperazin-2-onderivater, fremstilling deraf og terapeutisk anvendelse deraf
BRPI0821482A2 (pt) 3-n-fenil-1,3,4-oxadiazolona 5-o-substituída, seu uso, sua composição e seu processo de preparação
BRPI0821991A2 (pt) Derivados de 2-heteroaroil-imidazo[1,2-alfa] piridina, sua preparação e sua aplicação em terapêutica
BRPI1008660A2 (pt) derivados de n-[(2-aza-biciclo[2.1.1] hex-1-il)-aril-metil]benzamida, sua preparação e sua aplicação em teraêutica

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]