BRPI0814931A2 - Composto com atividade contra hcv, sua composição e seu uso - Google Patents

Composto com atividade contra hcv, sua composição e seu uso

Info

Publication number: BRPI0814931A2
Authority: BR; Brazil
Prior art keywords: composite; composition; hcv activity; hcv; activity
Prior art date: 2007-08-09

Application number

BRPI0814931-3A2A

Other languages

English (en)

Inventor

Scott W Martins

Carl P Bergstrom

Robert G Gentles

Kap-Sun Yeung

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-08-09

Filing date

2008-08-01

Publication date

2015-02-03

2008-08-01 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

2015-02-03 Publication of BRPI0814931A2 publication Critical patent/BRPI0814931A2/pt

Links

239000002131 composite material Substances 0.000 title 1
239000000203 mixture Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

BRPI0814931-3A2A 2007-08-09 2008-08-01 Composto com atividade contra hcv, sua composição e seu uso BRPI0814931A2 (pt)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US95481407P	2007-08-09	2007-08-09
US4994408P	2008-05-02	2008-05-02
US12/180,994 US7652004B2 (en)	2007-08-09	2008-07-28	Compounds for the treatment of hepatitis C
PCT/US2008/071881 WO2009029384A2 (en)	2007-08-09	2008-08-01	Compounds for the treatment of hepatitis c

Publications (1)

Publication Number	Publication Date
BRPI0814931A2 true BRPI0814931A2 (pt)	2015-02-03

Family

ID=40261456

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0814931-3A2A BRPI0814931A2 (pt)	2007-08-09	2008-08-01	Composto com atividade contra hcv, sua composição e seu uso

Country Status (18)

Country	Link
US (1)	US7652004B2 (pt)
EP (1)	EP2183252B1 (pt)
JP (1)	JP5465670B2 (pt)
KR (1)	KR20100066492A (pt)
CN (1)	CN101821267B (pt)
AR (1)	AR067897A1 (pt)
AU (1)	AU2008293845B2 (pt)
BR (1)	BRPI0814931A2 (pt)
CA (1)	CA2695781A1 (pt)
CL (1)	CL2008002353A1 (pt)
CO (1)	CO6251359A2 (pt)
EA (1)	EA015978B1 (pt)
MX (1)	MX2010001416A (pt)
NZ (1)	NZ583149A (pt)
PE (1)	PE20090618A1 (pt)
TW (1)	TW200906418A (pt)
WO (1)	WO2009029384A2 (pt)
ZA (1)	ZA201000923B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1688420A4 (en) *	2003-11-19	2008-10-22	Japan Tobacco Inc	5-5 LOW-CONDENSED HETEROCYCLIC COMPOUND AND THEIR USE AS HCV POLYMERASE INHIBITOR
US20070049593A1 (en)	2004-02-24	2007-03-01	Japan Tobacco Inc.	Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor
US7659263B2 (en)	2004-11-12	2010-02-09	Japan Tobacco Inc.	Thienopyrrole compound and use thereof as HCV polymerase inhibitor
US8143243B2 (en) *	2007-08-09	2012-03-27	Bristol-Myers Squibb Company	Compounds for the treatment of hepatitis C
AU2007361468A1 (en) *	2007-11-20	2009-05-28	Bristol-Myers Squibb Company	Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors
US8129367B2 (en) *	2007-11-21	2012-03-06	Bristol-Myers Squibb Company	Compounds for the treatment of Hepatitis C
ATE531373T1 (de)	2008-03-27	2011-11-15	Bristol Myers Squibb Co	Aromatische heterocyclische kondensierte indolobenzadiazepin-hcv-ns5b-inhibitoren
US8133884B2 (en) *	2008-05-06	2012-03-13	Bristol-Myers Squibb Company	Compounds for the treatment of hepatitis C
JP2012517468A (ja) *	2009-02-11	2012-08-02	ブリストル−マイヤーズスクイブカンパニー	Ｃ型肝炎治療のための化合物
CN106986862A (zh)	2010-12-22	2017-07-28	Abbvie 公司	丙型肝炎抑制剂及其用途
WO2012176717A1 (ja) *	2011-06-22	2012-12-27	セントラル硝子株式会社	ピラゾール化合物の製造方法
JP5915004B2 (ja) *	2011-06-22	2016-05-11	セントラル硝子株式会社	ピラゾール化合物の製造方法
CA2879398A1 (en) *	2012-07-18	2014-01-23	Bristol-Myers Squibb Holdings Ireland Unlimited Company	Novel methods and intermediates for the preparation of (4bs,5ar)-12-cyclohexyl-n-(n,n-dimethylsulfamoyl)-3-methoxy-5a-((1r,5s)-3-methyl-3,8-diazabicyclo[3.2.1]octane-8-carbonyl)-4b,5,5a,6-tetrahydrobenzo [3,4]cyclopropa[5,6]azepino[1,2-a]indole-9-carboxamide

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT1719773E (pt)	2004-02-24	2009-06-03	Japan Tobacco Inc	Compostos heterotetracíclicos fundidos e a sua utilização como inibidores da polimerase do hcv
US7153848B2 (en)	2004-08-09	2006-12-26	Bristol-Myers Squibb Company	Inhibitors of HCV replication
CA2585084A1 (en)	2004-10-26	2006-05-04	Immacolata Conte	Tetracyclic indole derivatives as antiviral agents
GB0518390D0 (en)	2005-09-09	2005-10-19	Angeletti P Ist Richerche Bio	Therapeutic compounds
US7399758B2 (en) *	2005-09-12	2008-07-15	Meanwell Nicholas A	Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors
US7473688B2 (en)	2005-09-13	2009-01-06	Bristol-Myers Squibb Company	Indolobenzazepine HCV NS5B inhibitors
US7456165B2 (en)	2006-02-08	2008-11-25	Bristol-Myers Squibb Company	HCV NS5B inhibitors
GB0608928D0 (en)	2006-05-08	2006-06-14	Angeletti P Ist Richerche Bio	Therapeutic agents
US7456166B2 (en)	2006-05-17	2008-11-25	Bristol-Myers Squibb Company	Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors
US7521441B2 (en)	2006-05-22	2009-04-21	Bristol-Myers Squibb Company	Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors
ES2343914T3 (es)	2006-05-25	2010-08-12	Bristol-Myers Squibb Company	Inhibidores de ns5b de hcv de indolobenzazepina condensada con ciclopropilo.
WO2007140200A2 (en)	2006-05-25	2007-12-06	Bristol-Myers Squibb Company	Cyclopropyl fused indolobenzazepine hcv ns5b inhibitors
US7452876B2 (en)	2006-06-08	2008-11-18	Bristol-Myers Squibb Company	Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors
US7541351B2 (en)	2007-01-11	2009-06-02	Bristol-Myers Squibb Company	Compounds for the treatment of hepatitis C
US7517872B2 (en)	2007-02-22	2009-04-14	Bristol-Myers Squibb Company	Compounds for the treatment of hepatitis C
US7541353B2 (en)	2007-03-14	2009-06-02	Bristol-Myers Squibb Company	Compounds for the treatment of hepatitis C
US7547690B2 (en)	2007-03-14	2009-06-16	Bristol-Myers Squibb Company	Compounds for the treatment of Hepatitis C
US7538102B2 (en)	2007-03-14	2009-05-26	Bristol-Myers Squibb Company	Compounds for the treatment of Hepatitis C
US7521444B2 (en)	2007-03-14	2009-04-21	Bristol-Myers Squibb Company	Compounds for the treatment of hepatitis C
US7538103B2 (en)	2007-03-15	2009-05-26	Bristol-Myers Squibb Company	Compounds for the treatment of hepatitis C

2008
- 2008-07-28 US US12/180,994 patent/US7652004B2/en active Active
- 2008-08-01 CN CN2008801108622A patent/CN101821267B/zh not_active Expired - Fee Related
- 2008-08-01 JP JP2010520215A patent/JP5465670B2/ja not_active Expired - Fee Related
- 2008-08-01 CA CA2695781A patent/CA2695781A1/en not_active Abandoned
- 2008-08-01 WO PCT/US2008/071881 patent/WO2009029384A2/en not_active Ceased
- 2008-08-01 NZ NZ583149A patent/NZ583149A/en not_active IP Right Cessation
- 2008-08-01 AU AU2008293845A patent/AU2008293845B2/en not_active Ceased
- 2008-08-01 EP EP08828571.3A patent/EP2183252B1/en not_active Not-in-force
- 2008-08-01 KR KR1020107005086A patent/KR20100066492A/ko not_active Withdrawn
- 2008-08-01 EA EA201000277A patent/EA015978B1/ru not_active IP Right Cessation
- 2008-08-01 BR BRPI0814931-3A2A patent/BRPI0814931A2/pt not_active IP Right Cessation
- 2008-08-01 MX MX2010001416A patent/MX2010001416A/es active IP Right Grant
- 2008-08-08 PE PE2008001327A patent/PE20090618A1/es not_active Application Discontinuation
- 2008-08-08 CL CL200802353A patent/CL2008002353A1/es unknown
- 2008-08-08 AR ARP080103488A patent/AR067897A1/es unknown
- 2008-08-08 TW TW097130410A patent/TW200906418A/zh unknown
2010
- 2010-02-03 CO CO10011252A patent/CO6251359A2/es not_active Application Discontinuation
- 2010-02-08 ZA ZA2010/00923A patent/ZA201000923B/en unknown

Also Published As

Publication number	Publication date
CO6251359A2 (es)	2011-02-21
EP2183252B1 (en)	2015-01-14
JP2010535787A (ja)	2010-11-25
JP5465670B2 (ja)	2014-04-09
CN101821267A (zh)	2010-09-01
EA015978B1 (ru)	2012-01-30
CL2008002353A1 (es)	2008-10-24
ZA201000923B (en)	2011-04-28
US7652004B2 (en)	2010-01-26
MX2010001416A (es)	2010-03-01
EA201000277A1 (ru)	2010-06-30
CN101821267B (zh)	2013-07-10
AR067897A1 (es)	2009-10-28
AU2008293845A1 (en)	2009-03-05
EP2183252A2 (en)	2010-05-12
US20090074715A1 (en)	2009-03-19
PE20090618A1 (es)	2009-05-16
TW200906418A (en)	2009-02-16
WO2009029384A2 (en)	2009-03-05
KR20100066492A (ko)	2010-06-17
NZ583149A (en)	2011-07-29
WO2009029384A3 (en)	2009-05-28
CA2695781A1 (en)	2009-03-05
AU2008293845B2 (en)	2013-02-14

Legal Events

Date	Code	Title	Description
2016-09-20	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 8A ANUIDADE.
2017-01-10	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

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