BRPI1008692A2 - moléculas de anticorpos tendo especificidade para ox40 humano. - Google Patents

moléculas de anticorpos tendo especificidade para ox40 humano.

Info

Publication number
BRPI1008692A2
BRPI1008692A2 BRPI1008692A BRPI1008692A BRPI1008692A2 BR PI1008692 A2 BRPI1008692 A2 BR PI1008692A2 BR PI1008692 A BRPI1008692 A BR PI1008692A BR PI1008692 A BRPI1008692 A BR PI1008692A BR PI1008692 A2 BRPI1008692 A2 BR PI1008692A2
Authority
BR
Brazil
Prior art keywords
specificity
human
antibody molecules
antibody
molecules
Prior art date
Application number
BRPI1008692A
Other languages
English (en)
Inventor
Alastair Griffiths Lawson
Andrew George Popplewell
Andrew Malcolm Nesbitt
Diana Shpektor
Stephen Graham Shaw
Yi Zhang
Original Assignee
Ucb Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42634416&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI1008692(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ucb Pharma Sa filed Critical Ucb Pharma Sa
Publication of BRPI1008692A2 publication Critical patent/BRPI1008692A2/pt
Publication of BRPI1008692B1 publication Critical patent/BRPI1008692B1/pt
Publication of BRPI1008692B8 publication Critical patent/BRPI1008692B8/pt

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    • C—CHEMISTRY; METALLURGY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K2317/55—Fab or Fab'
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    • C07K—PEPTIDES
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Animal Behavior & Ethology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Epidemiology (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
BRPI1008692A 2009-02-17 2010-02-17 anticorpo antagonista tendo especificidade para ox40 humano, sequência de dna isolado, vetor de clonagem ou de expressão, célula hospedeira, processo para a produção do referido anticorpo, composição farmacêutica, uso do 5 referido anticorpo e proteína de fusão BRPI1008692B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15303809P 2009-02-17 2009-02-17
US61/153,038 2009-02-17
PCT/US2010/024377 WO2010096418A2 (en) 2009-02-17 2010-02-17 Antibody molecules having specificity for human ox40

Publications (3)

Publication Number Publication Date
BRPI1008692A2 true BRPI1008692A2 (pt) 2016-03-08
BRPI1008692B1 BRPI1008692B1 (pt) 2020-10-27
BRPI1008692B8 BRPI1008692B8 (pt) 2021-05-25

Family

ID=42634416

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1008692A BRPI1008692B8 (pt) 2009-02-17 2010-02-17 anticorpo antagonista tendo especificidade para ox40 humano, sequência de dna isolado, vetor de clonagem ou de expressão, célula hospedeira, processo para a produção do referido anticorpo, composição farmacêutica, uso do 5 referido anticorpo e proteína de fusão

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US (3) US8614295B2 (pt)
EP (1) EP2398498B1 (pt)
JP (2) JP5782385B2 (pt)
KR (1) KR101761929B1 (pt)
CN (1) CN102741287B (pt)
AR (1) AR075504A1 (pt)
AU (1) AU2010216152B2 (pt)
BR (1) BRPI1008692B8 (pt)
CA (1) CA2751477C (pt)
CL (1) CL2011001994A1 (pt)
CO (1) CO6410312A2 (pt)
CY (1) CY1121431T1 (pt)
DK (1) DK2398498T3 (pt)
EA (1) EA037792B1 (pt)
ES (1) ES2699716T3 (pt)
HR (1) HRP20181932T1 (pt)
HU (1) HUE042114T2 (pt)
IL (1) IL214282A (pt)
LT (1) LT2398498T (pt)
MA (1) MA33122B1 (pt)
MX (1) MX2011008697A (pt)
MY (1) MY157473A (pt)
NZ (1) NZ594315A (pt)
PE (1) PE20120211A1 (pt)
PL (1) PL2398498T3 (pt)
PT (1) PT2398498T (pt)
SG (3) SG173620A1 (pt)
SI (1) SI2398498T1 (pt)
TN (1) TN2011000374A1 (pt)
TW (1) TWI476281B (pt)
UA (1) UA107341C2 (pt)
UY (1) UY32451A (pt)
WO (1) WO2010096418A2 (pt)
ZA (1) ZA201105500B (pt)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2398498B1 (en) * 2009-02-17 2018-09-05 UCB Biopharma SPRL Antibody molecules having specificity for human ox40
GB0920127D0 (en) 2009-11-17 2009-12-30 Ucb Pharma Sa Antibodies
PL2609118T3 (pl) 2010-08-23 2017-07-31 Board Of Regents, The University Of Texas System Przeciwciała anty-OX40 i sposoby ich stosowania
JP6093712B2 (ja) 2010-12-22 2017-03-08 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー インターロイキン２のスーパーアゴニストおよびアンタゴニスト
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Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2762 DE 12-12-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.