BRPI1008930A2 - formulação moduladas pelo ph para liberação pulmonar - Google Patents

formulação moduladas pelo ph para liberação pulmonar

Info

Publication number
BRPI1008930A2
BRPI1008930A2 BRPI1008930A BRPI1008930A BRPI1008930A2 BR PI1008930 A2 BRPI1008930 A2 BR PI1008930A2 BR PI1008930 A BRPI1008930 A BR PI1008930A BR PI1008930 A BRPI1008930 A BR PI1008930A BR PI1008930 A2 BRPI1008930 A2 BR PI1008930A2
Authority
BR
Brazil
Prior art keywords
modulated
formulation
pulmonary release
pulmonary
release
Prior art date
Application number
BRPI1008930A
Other languages
English (en)
Inventor
David C Cipolla
Igor Gonda
Original Assignee
Aradigm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aradigm Corp filed Critical Aradigm Corp
Publication of BRPI1008930A2 publication Critical patent/BRPI1008930A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI1008930A 2009-02-18 2010-01-26 formulação moduladas pelo ph para liberação pulmonar BRPI1008930A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15355609P 2009-02-18 2009-02-18
PCT/US2010/022071 WO2010096242A1 (en) 2009-02-18 2010-01-26 Ph-modulated formulations for pulmonary delivery

Publications (1)

Publication Number Publication Date
BRPI1008930A2 true BRPI1008930A2 (pt) 2016-03-15

Family

ID=42560133

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1008930A BRPI1008930A2 (pt) 2009-02-18 2010-01-26 formulação moduladas pelo ph para liberação pulmonar

Country Status (10)

Country Link
US (3) US20100209538A1 (pt)
EP (1) EP2398462A4 (pt)
JP (2) JP5960434B2 (pt)
CN (2) CN102395356A (pt)
AU (1) AU2010216348B2 (pt)
BR (1) BRPI1008930A2 (pt)
CA (1) CA2752296C (pt)
HK (1) HK1219047A1 (pt)
RU (1) RU2606175C2 (pt)
WO (1) WO2010096242A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104208045A (zh) * 2013-05-29 2014-12-17 天津金耀集团有限公司 一种含有青霉素类抗生素、糖皮质激素的复方的吸入制剂
CN104208060A (zh) * 2013-05-29 2014-12-17 天津金耀集团有限公司 一种青霉素类抗生素的吸入制剂
CN108926570A (zh) * 2017-05-27 2018-12-04 上海颢峰医药科技有限公司 头孢类抗生素在制备预防/治疗肺动脉高压药物中的应用
IL278513B (en) 2018-05-07 2022-09-01 Pharmosa Biopharm Inc A pharmaceutical preparation for the controlled release of treprostinil
TWI757739B (zh) 2019-05-14 2022-03-11 國邑藥品科技股份有限公司 包含弱酸藥物之醫藥組成物及其用途
GB202006563D0 (en) * 2020-05-04 2020-06-17 Nicoventures Trading Ltd Aerosol generation
CN113257405B (zh) * 2021-06-24 2021-09-28 北京力耘柯创医学研究院 基于传感器采集营养数据的处理系统

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6004951A (en) * 1989-11-22 1999-12-21 Bernstein; Lawrence Richard Administration of gallium complexes of 3-hydroxy-4-pyrones to provide physiologically active gallium levels in a mammalian individual
DE69033606T2 (de) * 1990-01-12 2001-04-26 New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery Verfahren zur verbesserung der wundheilung und gewebeerneuerung
US5175006A (en) * 1990-09-21 1992-12-29 The Ohio State University Method of treating arthritis using gallium compounds
AU2672892A (en) * 1991-09-17 1993-04-27 Alcon Laboratories, Inc. Compositions containing quinolone antibiotics and sulfonate of polystyrol
US5497763A (en) * 1993-05-21 1996-03-12 Aradigm Corporation Disposable package for intrapulmonary delivery of aerosolized formulations
US7244714B1 (en) * 1998-06-12 2007-07-17 Aradigm Corporation Methods of delivering aerosolized polynucleotides to the respiratory tract
KR100595956B1 (ko) * 1998-08-21 2006-07-03 센주 세이야꾸 가부시키가이샤 수성액 제약학적 조성물
TR200401980T4 (tr) * 2001-07-02 2004-09-21 Chiesi Farmaceutici S.P.A. Aerosol olarak uygulama için en uygun hale getirilmiş tobramisin formülasyonu
JP2005530704A (ja) * 2002-03-05 2005-10-13 トランセイブ, インク. 細胞内感染を予防及び治療するための吸入システム
US20080261902A1 (en) * 2005-04-04 2008-10-23 Shenzhen Neptunus Pharmaceutical Co., Ltd. Pharmaceutical composition containing polydatin and its application
EP2594272B1 (en) * 2005-05-18 2018-07-11 Horizon Orphan LLC Aerosolized fluoroquinolones and uses thereof
US7838532B2 (en) * 2005-05-18 2010-11-23 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
MX2008010222A (es) * 2006-02-10 2008-10-17 Pari Pharma Gmbh Antibioticos nebulizados para terapia de inhalacion.
JP2009544716A (ja) * 2006-07-27 2009-12-17 ノバルティス アクチエンゲゼルシャフト 肺送達のためのインスリン含有エアロゾル化可能製剤
EP2056794A4 (en) * 2006-08-08 2012-12-26 Univ Texas MULTIPLE ADMINISTRATION OF ACTIVE SUBSTANCES
WO2008025560A1 (en) * 2006-09-01 2008-03-06 Pari Pharma Gmbh Methods for taste masking of nebulised compositions for nasal and pulmonary inhalation therapy
AU2008279129A1 (en) * 2007-07-24 2009-01-29 Nexbio, Inc. Technology for the preparation of microparticles

Also Published As

Publication number Publication date
JP5960434B2 (ja) 2016-08-02
JP6188173B2 (ja) 2017-08-30
JP2012518036A (ja) 2012-08-09
EP2398462A4 (en) 2012-07-25
US20100209538A1 (en) 2010-08-19
AU2010216348B2 (en) 2015-01-22
CN102395356A (zh) 2012-03-28
HK1219047A1 (zh) 2017-03-24
US20200297722A1 (en) 2020-09-24
US20160331744A1 (en) 2016-11-17
EP2398462A1 (en) 2011-12-28
WO2010096242A1 (en) 2010-08-26
RU2011138178A (ru) 2013-03-27
AU2010216348A1 (en) 2011-09-08
CN105362256A (zh) 2016-03-02
RU2606175C2 (ru) 2017-01-10
CA2752296A1 (en) 2010-08-26
JP2016164183A (ja) 2016-09-08
CA2752296C (en) 2018-09-11

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

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