BRPI1009263A2 - alfa-amilases relacionadas com cepa de bacillus megaterium dsm90 e métodos de uso das mesmas. - Google Patents

alfa-amilases relacionadas com cepa de bacillus megaterium dsm90 e métodos de uso das mesmas.

Info

Publication number
BRPI1009263A2
BRPI1009263A2 BRPI1009263A BRPI1009263A BRPI1009263A2 BR PI1009263 A2 BRPI1009263 A2 BR PI1009263A2 BR PI1009263 A BRPI1009263 A BR PI1009263A BR PI1009263 A BRPI1009263 A BR PI1009263A BR PI1009263 A2 BRPI1009263 A2 BR PI1009263A2
Authority
BR
Brazil
Prior art keywords
dsm90
alpha
strain
methods
bacillus megaterium
Prior art date
Application number
BRPI1009263A
Other languages
English (en)
Inventor
Brian E Jones
Marc Kolkman
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Publication of BRPI1009263A2 publication Critical patent/BRPI1009263A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01001—Alpha-amylase (3.2.1.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BRPI1009263A 2009-03-10 2010-02-24 alfa-amilases relacionadas com cepa de bacillus megaterium dsm90 e métodos de uso das mesmas. BRPI1009263A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15895009P 2009-03-10 2009-03-10
PCT/US2010/025174 WO2010104675A1 (en) 2009-03-10 2010-02-24 Bacillus megaterium strain dsm90-related alpha-amylases, and methods of use, thereof

Publications (1)

Publication Number Publication Date
BRPI1009263A2 true BRPI1009263A2 (pt) 2015-10-06

Family

ID=42112218

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1009263A BRPI1009263A2 (pt) 2009-03-10 2010-02-24 alfa-amilases relacionadas com cepa de bacillus megaterium dsm90 e métodos de uso das mesmas.

Country Status (5)

Country Link
US (1) US20120172275A1 (pt)
EP (1) EP2406373B1 (pt)
CN (1) CN102341495A (pt)
BR (1) BRPI1009263A2 (pt)
WO (1) WO2010104675A1 (pt)

Families Citing this family (234)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102304540B (zh) * 2011-08-26 2013-10-09 华东理工大学 一种在里氏木霉分泌表达外源蛋白的表达设备及其应用
CN110777132B (zh) * 2013-03-11 2024-03-22 丹尼斯科美国公司 α-淀粉酶组合变体
EP2997143A1 (en) 2013-05-17 2016-03-23 Novozymes A/S Polypeptides having alpha amylase activity
WO2014194054A1 (en) 2013-05-29 2014-12-04 Danisco Us Inc. Novel metalloproteases
US20160160202A1 (en) 2013-05-29 2016-06-09 Danisco Us Inc. Novel metalloproteases
EP4159854A1 (en) 2013-05-29 2023-04-05 Danisco US Inc Novel metalloproteases
WO2014194117A2 (en) 2013-05-29 2014-12-04 Danisco Us Inc. Novel metalloproteases
CN118813589A (zh) 2013-06-06 2024-10-22 诺维信公司 α-淀粉酶变体以及对其进行编码的多核苷酸
CN105358686A (zh) 2013-07-29 2016-02-24 诺维信公司 蛋白酶变体以及对其进行编码的多核苷酸
CN105358684A (zh) 2013-07-29 2016-02-24 诺维信公司 蛋白酶变体以及对其进行编码的多核苷酸
US20160160199A1 (en) * 2013-10-03 2016-06-09 Danisco Us Inc. Alpha-amylases from exiguobacterium, and methods of use, thereof
EP3514230B1 (en) 2013-12-13 2021-09-22 Danisco US Inc. Serine proteases of bacillus species
WO2015089447A1 (en) 2013-12-13 2015-06-18 Danisco Us Inc. Serine proteases of the bacillus gibsonii-clade
AU2014366222B2 (en) 2013-12-16 2018-07-19 Nutrition & Biosciences USA 4, Inc. Use of poly alpha-1,3-glucan ethers as viscosity modifiers
JP6559139B2 (ja) 2013-12-18 2019-08-14 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ カチオン性ポリα−１，３−グルカンエーテル
US20150232785A1 (en) 2014-02-14 2015-08-20 E I Du Pont De Nemours And Company Polysaccharides for viscosity modification
ES2734726T3 (es) 2014-03-11 2019-12-11 Du Pont Poli alfa-1,2-glucano oxidado como reforzante de detergente
JP6585698B2 (ja) 2014-03-21 2019-10-02 ダニスコ・ユーエス・インク バチルス（Ｂａｃｉｌｌｕｓ）種のセリンプロテアーゼ
WO2015150457A1 (en) 2014-04-01 2015-10-08 Novozymes A/S Polypeptides having alpha amylase activity
US20170121695A1 (en) 2014-06-12 2017-05-04 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
EP3158043B1 (en) 2014-06-19 2021-03-10 Nutrition & Biosciences USA 4, Inc. Compositions containing one or more poly alpha-1,3-glucan ether compounds
US9714403B2 (en) 2014-06-19 2017-07-25 E I Du Pont De Nemours And Company Compositions containing one or more poly alpha-1,3-glucan ether compounds
US10626388B2 (en) 2014-07-04 2020-04-21 Novozymes A/S Subtilase variants and polynucleotides encoding same
EP3878960A1 (en) 2014-07-04 2021-09-15 Novozymes A/S Subtilase variants and polynucleotides encoding same
EP3207129B1 (en) 2014-10-17 2019-11-20 Danisco US Inc. Serine proteases of bacillus species
WO2016069552A1 (en) 2014-10-27 2016-05-06 Danisco Us Inc. Serine proteases
EP3212781B1 (en) 2014-10-27 2019-09-18 Danisco US Inc. Serine proteases
EP3957729A1 (en) 2014-10-27 2022-02-23 Danisco US Inc. Serine proteases
WO2016069544A1 (en) 2014-10-27 2016-05-06 Danisco Us Inc. Serine proteases
US20180010074A1 (en) 2014-10-27 2018-01-11 Danisco Us Inc. Serine proteases of bacillus species
WO2016079110A2 (en) 2014-11-19 2016-05-26 Novozymes A/S Use of enzyme for cleaning
EP3690037A1 (en) 2014-12-04 2020-08-05 Novozymes A/S Subtilase variants and polynucleotides encoding same
CN107002049A (zh) 2014-12-16 2017-08-01 诺维信公司 具有n‑乙酰基葡萄糖胺氧化酶活性的多肽
DK3234093T3 (da) 2014-12-19 2020-08-17 Novozymes As Proteasevarianter og polynukleotider, som koder for dem
DK3234123T3 (da) 2014-12-19 2020-08-24 Novozymes As Proteasevarianter og polynukleotider, som koder for dem
JP2018512109A (ja) 2014-12-23 2018-05-17 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ 酵素により製造されるセルロース
EP3294884B1 (en) 2015-05-13 2021-01-27 Danisco US Inc. Aprl-clade protease variants and uses thereof
EP3287513A1 (en) 2015-06-04 2018-02-28 The Procter & Gamble Company Hand dishwashing liquid detergent composition
ES2712459T3 (es) 2015-06-04 2019-05-13 Procter & Gamble Composición detergente líquida para lavado de vajillas a mano
EP3101102B2 (en) 2015-06-05 2023-12-13 The Procter & Gamble Company Compacted liquid laundry detergent composition
EP3101107B1 (en) 2015-06-05 2019-04-24 The Procter and Gamble Company Compacted liquid laundry detergent composition
PL3101100T3 (pl) 2015-06-05 2018-07-31 The Procter And Gamble Company Zagęszczone płynne kompozycje detergentowe do prania
FI3307427T3 (fi) 2015-06-09 2023-11-09 Danisco Us Inc Osmoottiset puhkeavat kapselit
WO2016201069A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc Low-density enzyme-containing particles
WO2016201040A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc. Water-triggered enzyme suspension
EP4234693A3 (en) 2015-06-17 2023-11-01 Danisco US Inc Bacillus gibsonii-clade serine proteases
WO2016202785A1 (en) 2015-06-17 2016-12-22 Novozymes A/S Container
EP3106508B1 (en) 2015-06-18 2019-11-20 Henkel AG & Co. KGaA Detergent composition comprising subtilase variants
EP3872175A1 (en) 2015-06-18 2021-09-01 Novozymes A/S Subtilase variants and polynucleotides encoding same
EP3317388B1 (en) 2015-06-30 2019-11-13 Novozymes A/S Laundry detergent composition, method for washing and use of composition
EP3350323B1 (en) 2015-09-17 2021-04-14 Novozymes A/S Polypeptides having xanthan degrading activity and polynucleotides encoding same
KR20180053365A (ko) 2015-09-17 2018-05-21 헨켈 아게 운트 코. 카게아아 크산탄 분해 활성을 갖는 폴리펩티드를 포함하는 세제 조성물
CA2996749C (en) 2015-10-28 2023-10-10 Novozymes A/S Detergent composition comprising amylase and protease variants
WO2017079751A1 (en) 2015-11-05 2017-05-11 Danisco Us Inc Paenibacillus sp. mannanases
WO2017079756A1 (en) 2015-11-05 2017-05-11 Danisco Us Inc Paenibacillus and bacillus spp. mannanases
JP7045313B2 (ja) 2015-11-13 2022-03-31 ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー，インコーポレイテッド 洗濯ケアおよび織物ケアにおいて使用するためのグルカン繊維組成物
WO2017083229A1 (en) 2015-11-13 2017-05-18 E. I. Du Pont De Nemours And Company Glucan fiber compositions for use in laundry care and fabric care
JP6997706B2 (ja) 2015-11-13 2022-01-18 ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー，インコーポレイテッド 洗濯ケアおよび織物ケアにおいて使用するためのグルカン繊維組成物
EP3387124B1 (en) 2015-12-09 2021-05-19 Danisco US Inc. Alpha-amylase combinatorial variants
US20180362946A1 (en) 2015-12-18 2018-12-20 Danisco Us Inc. Polypeptides with endoglucanase activity and uses thereof
DE102016201643A1 (de) * 2016-02-03 2017-08-03 Henkel Ag & Co. Kgaa Verbesserte Waschleistung durch eine alpha-Amylase aus Bacillus cereus
WO2017174769A2 (en) 2016-04-08 2017-10-12 Novozymes A/S Detergent compositions and uses of the same
CA3022875A1 (en) 2016-05-03 2017-11-09 Danisco Us Inc Protease variants and uses thereof
BR112018072586A2 (pt) 2016-05-05 2019-02-19 Danisco Us Inc variantes de protease e usos das mesmas
US11661567B2 (en) 2016-05-31 2023-05-30 Danisco Us Inc. Protease variants and uses thereof
EP3464582A1 (en) 2016-06-03 2019-04-10 Novozymes A/S Subtilase variants and polynucleotides encoding same
MX2018015559A (es) 2016-06-17 2019-06-06 Danisco Us Inc Variantes de proteasa y sus usos.
US11001787B2 (en) 2016-06-23 2021-05-11 Novozymes A/S Use of enzymes, composition and method for removing soil
CN117721095A (zh) 2016-06-30 2024-03-19 诺维信公司 脂肪酶变体及包含表面活性剂和脂肪酶变体的组合物
EP3284805B1 (en) 2016-08-17 2020-02-19 The Procter & Gamble Company Cleaning composition comprising enzymes
CN110023474A (zh) 2016-09-29 2019-07-16 诺维信公司 酶用于洗涤的用途、洗涤方法和器皿洗涤组合物
EP3535365A2 (en) 2016-11-07 2019-09-11 Danisco US Inc. Laundry detergent composition
US20190292494A1 (en) 2016-12-01 2019-09-26 Basf Se Stabilization of enzymes in compositions
WO2018108865A1 (en) 2016-12-12 2018-06-21 Novozymes A/S Use of polypeptides
US20200392477A1 (en) 2016-12-21 2020-12-17 Danisco Us Inc. Protease variants and uses thereof
EP4424805A3 (en) 2016-12-21 2024-11-20 Danisco Us Inc Bacillus gibsonii-clade serine proteases
WO2018169750A1 (en) 2017-03-15 2018-09-20 Danisco Us Inc Trypsin-like serine proteases and uses thereof
WO2018178061A1 (en) 2017-03-31 2018-10-04 Novozymes A/S Polypeptides having rnase activity
US11180720B2 (en) 2017-03-31 2021-11-23 Novozymes A/S Polypeptides having DNase activity
US20200040283A1 (en) 2017-03-31 2020-02-06 Danisco Us Inc Delayed release enzyme formulations for bleach-containing detergents
CN110651041A (zh) 2017-03-31 2020-01-03 诺维信公司 具有dna酶活性的多肽
WO2018177936A1 (en) 2017-03-31 2018-10-04 Novozymes A/S Polypeptides having dnase activity
WO2018185048A1 (en) 2017-04-03 2018-10-11 Novozymes A/S Recovery process
EP3607041A1 (en) 2017-04-04 2020-02-12 Novozymes A/S Glycosyl hydrolases
WO2018185150A1 (en) 2017-04-04 2018-10-11 Novozymes A/S Polypeptides
CA3058520A1 (en) 2017-04-06 2018-10-11 Novozymes A/S Detergent compositions and uses thereof
JP7032430B2 (ja) 2017-04-06 2022-03-08 ノボザイムス アクティーゼルスカブ クリーニング組成物及びその使用
WO2018184818A1 (en) 2017-04-06 2018-10-11 Novozymes A/S Cleaning compositions and uses thereof
EP3607042A1 (en) 2017-04-06 2020-02-12 Novozymes A/S Cleaning compositions and uses thereof
EP3607037A1 (en) 2017-04-06 2020-02-12 Novozymes A/S Cleaning compositions and uses thereof
US20200190437A1 (en) 2017-04-06 2020-06-18 Novozymes A/S Cleaning compositions and uses thereof
CN110709499A (zh) 2017-04-06 2020-01-17 诺维信公司 清洁组合物及其用途
EP3607043A1 (en) 2017-04-06 2020-02-12 Novozymes A/S Cleaning compositions and uses thereof
JP7680825B2 (ja) 2017-06-30 2025-05-21 ダニスコ・ユーエス・インク 低凝集の酵素含有粒子
MX2020002953A (es) 2017-09-20 2020-07-22 Novozymes As Uso de enzimas para mejorar la absorcion de agua y/o la blancura.
WO2019076800A1 (en) 2017-10-16 2019-04-25 Novozymes A/S CLEANING COMPOSITIONS AND USES THEREOF
EP4379029A1 (en) 2017-11-01 2024-06-05 Novozymes A/S Polypeptides and compositions comprising such polypeptides
CN111479919A (zh) 2017-11-01 2020-07-31 诺维信公司 多肽以及包含此类多肽的组合物
DE102017125560A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine iii enthalten
WO2019086532A1 (en) 2017-11-01 2019-05-09 Novozymes A/S Methods for cleaning medical devices
US20210071118A1 (en) 2017-11-29 2021-03-11 Basf Se Compositions, their manufacture and use
WO2019108599A1 (en) 2017-11-29 2019-06-06 Danisco Us Inc Subtilisin variants having improved stability
CN111742041B (zh) 2017-12-21 2023-06-06 丹尼斯科美国公司 包含耐热干燥剂的含酶的热熔细粒
US11560342B2 (en) 2018-01-03 2023-01-24 Monsanto Technology, Llc Bacillus isolates and uses thereof
MX2020008302A (es) 2018-02-08 2020-10-14 Danisco Us Inc Partículas de matriz de cera térmicamente resistentes para encapsulación de enzimas.
EP3768835A1 (en) 2018-03-23 2021-01-27 Novozymes A/S Subtilase variants and compositions comprising same
WO2019201793A1 (en) 2018-04-17 2019-10-24 Novozymes A/S Polypeptides comprising carbohydrate binding activity in detergent compositions and their use in reducing wrinkles in textile or fabric.
CN112368375A (zh) 2018-04-26 2021-02-12 巴斯夫欧洲公司 脂肪酶
EP3788145A1 (en) 2018-05-03 2021-03-10 Basf Se Amylase enzymes
WO2019238761A1 (en) 2018-06-15 2019-12-19 Basf Se Water soluble multilayer films containing wash active chemicals and enzymes
EP3799601A1 (en) 2018-06-19 2021-04-07 Danisco US Inc. Subtilisin variants
WO2019245704A1 (en) 2018-06-19 2019-12-26 Danisco Us Inc Subtilisin variants
CN112368363A (zh) 2018-06-28 2021-02-12 诺维信公司 洗涤剂组合物及其用途
EP3814489A1 (en) 2018-06-29 2021-05-05 Novozymes A/S Subtilase variants and compositions comprising same
EP3814473A1 (en) 2018-06-29 2021-05-05 Novozymes A/S Detergent compositions and uses thereof
CN112352039B (zh) 2018-07-02 2022-11-15 诺维信公司 清洁组合物及其用途
WO2020007875A1 (en) 2018-07-03 2020-01-09 Novozymes A/S Cleaning compositions and uses thereof
WO2020008024A1 (en) 2018-07-06 2020-01-09 Novozymes A/S Cleaning compositions and uses thereof
EP3818140A1 (en) 2018-07-06 2021-05-12 Novozymes A/S Cleaning compositions and uses thereof
US20210189295A1 (en) 2018-08-30 2021-06-24 Danisco Us Inc Enzyme-containing granules
WO2020068486A1 (en) 2018-09-27 2020-04-02 Danisco Us Inc Compositions for medical instrument cleaning
US20210340466A1 (en) 2018-10-01 2021-11-04 Novozymes A/S Detergent compositions and uses thereof
WO2020070014A1 (en) 2018-10-02 2020-04-09 Novozymes A/S Cleaning composition comprising anionic surfactant and a polypeptide having rnase activity
WO2020070209A1 (en) 2018-10-02 2020-04-09 Novozymes A/S Cleaning composition
CN112969788A (zh) 2018-10-02 2021-06-15 诺维信公司 用于清洁的核酸内切酶1核糖核酸酶
US20230287306A1 (en) 2018-10-02 2023-09-14 Novozymes A/S Cleaning Composition
WO2020070249A1 (en) 2018-10-03 2020-04-09 Novozymes A/S Cleaning compositions
EP3861008A1 (en) 2018-10-03 2021-08-11 Novozymes A/S Polypeptides having alpha-mannan degrading activity and polynucleotides encoding same
US20210395651A1 (en) 2018-10-05 2021-12-23 Basf Se Compounds stabilizing hydrolases in liquids
MX2021003930A (es) 2018-10-05 2021-06-04 Basf Se Compuestos estabilizadores de hidrolasas en liquidos.
EP3677676A1 (en) 2019-01-03 2020-07-08 Basf Se Compounds stabilizing amylases in liquids
EP3861114A1 (en) 2018-10-05 2021-08-11 Basf Se Compounds stabilizing amylases in liquids
WO2020074545A1 (en) 2018-10-11 2020-04-16 Novozymes A/S Cleaning compositions and uses thereof
EP3647397A1 (en) 2018-10-31 2020-05-06 Henkel AG & Co. KGaA Cleaning compositions containing dispersins iv
EP3647398B1 (en) 2018-10-31 2024-05-15 Henkel AG & Co. KGaA Cleaning compositions containing dispersins v
US12509672B2 (en) 2018-11-28 2025-12-30 Danisco Us Inc. Subtilisin variants having improved stability
EP3891277A1 (en) 2018-12-03 2021-10-13 Novozymes A/S Powder detergent compositions
WO2020114965A1 (en) 2018-12-03 2020-06-11 Novozymes A/S LOW pH POWDER DETERGENT COMPOSITION
WO2020127775A1 (en) 2018-12-21 2020-06-25 Novozymes A/S Detergent pouch comprising metalloproteases
US11959111B2 (en) 2018-12-21 2024-04-16 Novozymes A/S Polypeptides having peptidoglycan degrading activity and polynucleotides encoding same
WO2020169564A1 (en) 2019-02-20 2020-08-27 Basf Se Industrial fermentation process for bacillus using defined medium and trace element feed
MX2021010110A (es) 2019-02-20 2021-09-21 Basf Se Proceso de fermentacion industrial para bacillus mediante el uso de medio definido y alimentacion de magnesio.
EP3702452A1 (en) 2019-03-01 2020-09-02 Novozymes A/S Detergent compositions comprising two proteases
EP3942032A1 (en) 2019-03-21 2022-01-26 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
WO2020193534A2 (en) 2019-03-25 2020-10-01 Basf Se Amylase enzymes
EP3947665A2 (en) 2019-03-25 2022-02-09 Basf Se Amylase enzymes
WO2020193532A1 (en) 2019-03-25 2020-10-01 Basf Se Cleaning composition having amylase enzymes
WO2020229480A1 (en) 2019-05-14 2020-11-19 Basf Se Compounds stabilizing hydrolases in liquids
CN114174504A (zh) 2019-05-24 2022-03-11 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
CN114174486A (zh) 2019-06-06 2022-03-11 丹尼斯科美国公司 用于清洁的方法和组合物
US12146171B2 (en) 2019-06-13 2024-11-19 Basf Se Method of recovering a protein from fermentation broth using a divalent cation
PL3959326T3 (pl) 2019-07-05 2023-10-09 Basf Se Przemysłowy sposób fermentacji dla komórek bakteryjnych z wykorzystaniem kultury wstępnej okresowej z zasilaniem
US20220403298A1 (en) 2019-07-12 2022-12-22 Novozymes A/S Enzymatic emulsions for detergents
WO2021032881A1 (en) 2019-08-22 2021-02-25 Basf Se Amylase variants
US20220315866A1 (en) 2019-09-19 2022-10-06 Novozymes A/S Detergent Composition
EP4038170A1 (en) 2019-10-03 2022-08-10 Novozymes A/S Polypeptides comprising at least two carbohydrate binding domains
BR112022006082A2 (pt) 2019-10-18 2022-06-21 Basf Se Preparação enzimática, formulação de detergente, e, uso de pelo menos um diol
BR112021021050A2 (pt) 2019-11-29 2022-09-13 Basf Se Composição, uso de uma composição, polímero, processo para preparar polímeros, e, método para melhorar o desempenho de limpeza de uma composição líquida de detergente
WO2021115912A1 (en) 2019-12-09 2021-06-17 Basf Se Formulations comprising a hydrophobically modified polyethyleneimine and one or more enzymes
EP4077621A2 (en) 2019-12-20 2022-10-26 Henkel AG & Co. KGaA Cleaning compositions comprising dispersins viii
EP4077656A2 (en) 2019-12-20 2022-10-26 Novozymes A/S Polypeptides having proteolytic activity and use thereof
CN114829562A (zh) 2019-12-20 2022-07-29 汉高股份有限及两合公司 包含分散蛋白vi的清洁组合物
CN114829564A (zh) 2019-12-20 2022-07-29 汉高股份有限及两合公司 包含分散蛋白和糖酶的清洁组合物
EP4077617B1 (en) 2019-12-20 2026-03-18 Novozymes A/S Stabilized liquid boron-free enzyme compositions
WO2021214059A1 (en) 2020-04-21 2021-10-28 Novozymes A/S Cleaning compositions comprising polypeptides having fructan degrading activity
WO2021239818A1 (en) 2020-05-26 2021-12-02 Novozymes A/S Subtilase variants and compositions comprising same
CN115836125A (zh) 2020-06-24 2023-03-21 诺维信公司 纤维素酶用于从纺织品去除尘螨的用途
EP3936593A1 (en) 2020-07-08 2022-01-12 Henkel AG & Co. KGaA Cleaning compositions and uses thereof
WO2022008732A1 (en) 2020-07-10 2022-01-13 Basf Se Enhancing the activity of antimicrobial preservatives
US20240034960A1 (en) 2020-08-27 2024-02-01 Danisco Us Inc Enzymes and enzyme compositions for cleaning
EP4204547A1 (en) 2020-08-28 2023-07-05 Novozymes A/S Protease variants with improved solubility
CN116096731A (zh) 2020-09-22 2023-05-09 巴斯夫欧洲公司 蛋白酶和蛋白酶抑制剂与第二酶的改进的组合
EP4217367A1 (en) 2020-09-22 2023-08-02 Basf Se Liquid composition comprising peptide aldehyde
US20250346879A1 (en) 2020-10-07 2025-11-13 Novozymes A/S Alpha-amylase variants
WO2022084303A2 (en) 2020-10-20 2022-04-28 Novozymes A/S Use of polypeptides having dnase activity
EP4015629A1 (en) 2020-12-18 2022-06-22 Basf Se Polymer mixtures for increasing stability and performance of hydrolase-containing detergents
EP4032966A1 (en) 2021-01-22 2022-07-27 Novozymes A/S Liquid enzyme composition with sulfite scavenger
EP4284906A1 (en) 2021-01-29 2023-12-06 Danisco US Inc. Compositions for cleaning and methods related thereto
CN116829709A (zh) 2021-02-12 2023-09-29 诺维信公司 α-淀粉酶变体
US20250075152A1 (en) 2021-02-12 2025-03-06 Novozymes A/S Stabilized biological detergents
JP2024508766A (ja) 2021-02-22 2024-02-28 ベーアーエスエフ・エスエー アミラーゼバリアント
EP4047088A1 (en) 2021-02-22 2022-08-24 Basf Se Amylase variants
US20240301328A1 (en) 2021-03-12 2024-09-12 Novozymes A/S Polypeptide variants
WO2022268885A1 (en) 2021-06-23 2022-12-29 Novozymes A/S Alpha-amylase polypeptides
US20240294888A1 (en) 2021-06-30 2024-09-05 Danisco Us Inc. Variant enzymes and uses thereof
EP4396320A2 (en) 2021-09-03 2024-07-10 Danisco US Inc. Laundry compositions for cleaning
CN117957318A (zh) 2021-09-13 2024-04-30 丹尼斯科美国公司 含有生物活性物质的颗粒
US20250051748A1 (en) 2021-12-16 2025-02-13 Danisco Us Inc. Subtilisin variants and methods of use
CN118679252A (zh) 2021-12-16 2024-09-20 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
EP4448750A2 (en) 2021-12-16 2024-10-23 Danisco US Inc. Subtilisin variants and uses thereof
US20250132404A1 (en) 2021-12-21 2025-04-24 Basf Se Battery passport
EP4206309A1 (en) 2021-12-30 2023-07-05 Novozymes A/S Protein particles with improved whiteness
CN118974227A (zh) 2022-03-01 2024-11-15 丹尼斯科美国公司 用于清洁的酶和酶组合物
JP2025507844A (ja) 2022-03-02 2025-03-21 ノボザイムス アクティーゼルスカブ 洗剤の持続可能性の改善のためのキシログルカナーゼの使用
CA3257053A1 (en) 2022-05-14 2023-11-23 Novozymes A/S COMPOSITIONS AND METHODS FOR THE PREVENTION, TREATMENT, SUPPRESSION AND/OR ELIMINATION OF PHYTOPATHOGENIC INFESTATIONS AND INFECTIONS
CN119487167A (zh) 2022-06-21 2025-02-18 丹尼斯科美国公司 用于清洁的包含具有嗜热菌蛋白酶活性的多肽的组合物和方法
WO2024012894A1 (en) 2022-07-15 2024-01-18 Basf Se Alkanolamine formates for enzyme stabilization in liquid formulations
US20260055347A1 (en) 2022-08-11 2026-02-26 Basf Se Amylase variants
CN119677846A (zh) 2022-08-11 2025-03-21 巴斯夫欧洲公司 淀粉酶变体
WO2024050339A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. Mannanase variants and methods of use
EP4581138A1 (en) 2022-09-02 2025-07-09 Danisco US Inc. Subtilisin variants and methods related thereto
WO2024094735A1 (en) 2022-11-04 2024-05-10 Basf Se Polypeptides having protease activity for use in detergent compositions
CN120693402A (zh) 2022-11-04 2025-09-23 巴斯夫欧洲公司 用于在洗涤剂组合物中使用的具有蛋白酶活性的多肽
WO2024094733A1 (en) 2022-11-04 2024-05-10 Basf Se Polypeptides having protease activity for use in detergent compositions
EP4615968A1 (en) 2022-11-09 2025-09-17 Danisco US Inc. Subtilisin variants and methods of use
CN120989059A (zh) 2022-12-05 2025-11-21 诺维信公司 蛋白酶变体以及编码其的多核苷酸
EP4389864A1 (en) 2022-12-20 2024-06-26 Basf Se Cutinases
CN120344647A (zh) 2022-12-23 2025-07-18 诺维信公司 包含过氧化氢酶和淀粉酶的洗涤剂组合物
EP4646473A1 (en) 2023-01-05 2025-11-12 Basf Se Use of foldases to improve heterologous expression of secreted molecules
EP4655371A1 (en) 2023-01-23 2025-12-03 Novozymes A/S Cleaning compositions and uses thereof
EP4658776A1 (en) 2023-02-01 2025-12-10 Danisco US Inc. Subtilisin variants and methods of use
EP4410938A1 (en) 2023-02-02 2024-08-07 AMSilk GmbH Automatic dishwashing composition comprising a structural polypeptide
CN120712348A (zh) 2023-03-06 2025-09-26 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
EP4680013A1 (en) 2023-03-16 2026-01-21 Nutrition & Biosciences USA 4, Inc. Brevibacillus fermentate extracts for cleaning and malodor control and use thereof
WO2024213755A1 (en) 2023-04-14 2024-10-17 Basf Se Porous starch
CN121039261A (zh) 2023-04-26 2025-11-28 诺维信公司 清洁组合物和清洁方法
EP4461796A1 (en) 2023-05-10 2024-11-13 Novozymes A/S Detergent composition comprising laccase
EP4461795A1 (en) 2023-05-10 2024-11-13 Novozymes A/S Detergent composition comprising laccase
MX2025014975A (es) 2023-06-13 2026-02-03 Basf Se Composiciones de limpieza estabilizadas que comprenden edds y enzimas y su uso
WO2025071996A1 (en) 2023-09-28 2025-04-03 Danisco Us Inc. Variant cutinase enzymes with improved solubility and uses thereof
WO2025085351A1 (en) 2023-10-20 2025-04-24 Danisco Us Inc. Subtilisin variants and methods of use
WO2025088003A1 (en) 2023-10-24 2025-05-01 Novozymes A/S Use of xyloglucanase for replacement of optical brightener
WO2025093368A1 (en) 2023-11-02 2025-05-08 Basf Se Enzyme stabilization in compositions containing a protease inhibitor
WO2025132258A1 (en) 2023-12-20 2025-06-26 Basf Se Stabilized enzyme composition comprising a protease
WO2025153046A1 (en) 2024-01-19 2025-07-24 Novozymes A/S Detergent compositions and uses thereof
WO2025202379A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
EP4624572A1 (en) 2024-03-27 2025-10-01 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202374A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202369A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202370A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025202372A1 (en) 2024-03-27 2025-10-02 Basf Se Polypeptides having protease activity for use in detergent compositions
WO2025257254A1 (en) 2024-06-12 2025-12-18 Novozymes A/S Lipases and lipase variants and the use thereof
WO2026024921A1 (en) 2024-07-25 2026-01-29 The Procter & Gamble Company Detergent composition comprising a subtilisin variant and methods of use
WO2026050315A1 (en) 2024-08-29 2026-03-05 Danisco Us Inc. Subtilisin variants and methods of use

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1372034A (en) 1970-12-31 1974-10-30 Unilever Ltd Detergent compositions
GB1483591A (en) 1973-07-23 1977-08-24 Novo Industri As Process for coating water soluble or water dispersible particles by means of the fluid bed technique
GB1590432A (en) 1976-07-07 1981-06-03 Novo Industri As Process for the production of an enzyme granulate and the enzyme granuate thus produced
DK187280A (da) 1980-04-30 1981-10-31 Novo Industri As Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode
DK263584D0 (da) 1984-05-29 1984-05-29 Novo Industri As Enzymholdige granulater anvendt som detergentadditiver
JPH0697997B2 (ja) 1985-08-09 1994-12-07 ギスト ブロカデス ナ−ムロ−ゼ フエンノ−トチヤツプ 新規の酵素的洗浄剤添加物
EG18543A (en) 1986-02-20 1993-07-30 Albright & Wilson Protected enzyme systems
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
US4810414A (en) 1986-08-29 1989-03-07 Novo Industri A/S Enzymatic detergent additive
NZ221627A (en) 1986-09-09 1993-04-28 Genencor Inc Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios
EP0305216B1 (en) 1987-08-28 1995-08-02 Novo Nordisk A/S Recombinant Humicola lipase and process for the production of recombinant humicola lipases
JPS6474992A (en) 1987-09-16 1989-03-20 Fuji Oil Co Ltd Dna sequence, plasmid and production of lipase
DK6488D0 (da) 1988-01-07 1988-01-07 Novo Industri As Enzymer
DE68924654T2 (de) 1988-01-07 1996-04-04 Novonordisk As Spezifische Protease.
JP3079276B2 (ja) 1988-02-28 2000-08-21 天野製薬株式会社 組換え体ｄｎａ、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法
US5776757A (en) 1988-03-24 1998-07-07 Novo Nordisk A/S Fungal cellulase composition containing alkaline CMC-endoglucanase and essentially no cellobiohydrolase and method of making thereof
JP2728531B2 (ja) 1988-03-24 1998-03-18 ノボ ノルディスク アクティーゼルスカブ セルラーゼ調製品
GB8915658D0 (en) 1989-07-07 1989-08-23 Unilever Plc Enzymes,their production and use
DE59101948D1 (de) 1990-04-14 1994-07-21 Kali Chemie Ag Alkalische bacillus-lipasen, hierfür codierende dna-sequenzen sowie bacilli, die diese lipasen produzieren.
DK115890D0 (da) 1990-05-09 1990-05-09 Novo Nordisk As Enzym
AU639570B2 (en) 1990-05-09 1993-07-29 Novozymes A/S A cellulase preparation comprising an endoglucanase enzyme
EP0548228B1 (en) 1990-09-13 1998-08-12 Novo Nordisk A/S Lipase variants
DE69126879T2 (de) 1990-09-28 1998-02-19 The Procter & Gamble Co., Cincinnati, Ohio Polyhydroxyfettsäureamidtenside zur erhöhung der enzymleistung
ES2174820T3 (es) 1991-01-16 2002-11-16 Procter & Gamble Composiciones detergentes compactas con celulasa de alta actividad.
PL170474B1 (pl) 1991-04-30 1996-12-31 Procter & Gamble C iekla kom pozycja detergentow a PL PL PL
EP0511456A1 (en) 1991-04-30 1992-11-04 The Procter & Gamble Company Liquid detergents with aromatic borate ester to inhibit proteolytic enzyme
KR100258460B1 (ko) 1991-05-01 2000-06-01 한센 핀 베네드 안정화 효소 및 세제 조성물
DK72992D0 (da) 1992-06-01 1992-06-01 Novo Nordisk As Enzym
DK88892D0 (da) 1992-07-06 1992-07-06 Novo Nordisk As Forbindelse
KR100303619B1 (ko) 1992-10-06 2001-11-22 피아 스타르 셀룰라제변이체
US5281526A (en) 1992-10-20 1994-01-25 Solvay Enzymes, Inc. Method of purification of amylase by precipitation with a metal halide and 4-hydroxybenzic acid or a derivative thereof
JP3618748B2 (ja) 1993-04-27 2005-02-09 ジェネンコー インターナショナル インコーポレイテッド 洗剤に使用する新しいリパーゼ変異体
DK52393D0 (pt) 1993-05-05 1993-05-05 Novo Nordisk As
JP2859520B2 (ja) 1993-08-30 1999-02-17 ノボ ノルディスク アクティーゼルスカブ リパーゼ及びそれを生産する微生物及びリパーゼ製造方法及びリパーゼ含有洗剤組成物
CN1133062A (zh) 1993-10-13 1996-10-09 诺沃挪第克公司 对过氧化氢稳定的过氧化物酶变体
JPH07143883A (ja) 1993-11-24 1995-06-06 Showa Denko Kk リパーゼ遺伝子及び変異体リパーゼ
WO1995022615A1 (en) 1994-02-22 1995-08-24 Novo Nordisk A/S A method of preparing a variant of a lipolytic enzyme
AU1890095A (en) 1994-03-08 1995-09-25 Novo Nordisk A/S Novel alkaline cellulases
JP3851656B2 (ja) 1994-05-04 2006-11-29 ジェネンコア インターナショナル インコーポレーテッド 改善された界面活性剤耐性を有するリパーゼ
WO1995035381A1 (en) 1994-06-20 1995-12-28 Unilever N.V. Modified pseudomonas lipases and their use
WO1996000292A1 (en) 1994-06-23 1996-01-04 Unilever N.V. Modified pseudomonas lipases and their use
ATE389012T1 (de) 1994-10-06 2008-03-15 Novozymes As Ein enzympräparat mit endoglucanase aktivität
BE1008998A3 (fr) 1994-10-14 1996-10-01 Solvay Lipase, microorganisme la produisant, procede de preparation de cette lipase et utilisations de celle-ci.
WO1996013580A1 (en) 1994-10-26 1996-05-09 Novo Nordisk A/S An enzyme with lipolytic activity
JPH08228778A (ja) 1995-02-27 1996-09-10 Showa Denko Kk 新規なリパーゼ遺伝子及びそれを用いたリパーゼの製造方法
WO1996029397A1 (en) 1995-03-17 1996-09-26 Novo Nordisk A/S Novel endoglucanases
ATE282087T1 (de) 1995-07-14 2004-11-15 Novozymes As Modifiziertes enzym mit lipolytischer aktivität
AU6655196A (en) 1995-08-11 1997-03-12 Novo Nordisk A/S Novel lipolytic enzymes
WO1998008940A1 (en) 1996-08-26 1998-03-05 Novo Nordisk A/S A novel endoglucanase
EP1726644A1 (en) 1996-09-17 2006-11-29 Novozymes A/S Cellulase variants
WO1998015257A1 (en) 1996-10-08 1998-04-16 Novo Nordisk A/S Diaminobenzoic acid derivatives as dye precursors
WO1998020115A1 (en) 1996-11-04 1998-05-14 Novo Nordisk A/S Subtilase variants and compositions
ATE409743T1 (de) 1996-11-04 2008-10-15 Novozymes As Subtilase varianten und verbindungen
US6159731A (en) 1997-02-12 2000-12-12 Massachusetts Institute Of Technology Daxx, a Fas-binding protein that activates JNK and apoptosis
DK2206768T3 (en) * 1997-10-13 2015-06-29 Novozymes As Alfa-amylasemutanter
CA2313950A1 (en) 1997-12-24 1999-07-08 James T. Kellis, Jr. An improved method of assaying for a preferred enzyme and /or preferred detergent composition
ES2322426T3 (es) * 1999-03-31 2009-06-22 Novozymes A/S Polipeptidos con actividad alfa-amilasa y acidos nucleicos que codifican a los mismos.
US6254645B1 (en) 1999-08-20 2001-07-03 Genencor International, Inc. Enzymatic modification of the surface of a polyester fiber or article
US6933140B1 (en) 1999-11-05 2005-08-23 Genencor International, Inc. Enzymes useful for changing the properties of polyester
ATE400648T1 (de) 2000-08-11 2008-07-15 Genencor Int Transformation von bacillus, transformanten und mutanten-bibliotheken
ATE510023T1 (de) * 2001-02-21 2011-06-15 Verenium Corp Enzyme mit alpha-amylase-aktivität und verfahren zu deren verwendung
DE10138753B4 (de) * 2001-08-07 2017-07-20 Henkel Ag & Co. Kgaa Wasch- und Reinigungsmittel mit Hybrid-Alpha-Amylasen
KR100625100B1 (ko) * 2002-07-15 2006-09-19 주식회사 제노포커스 말토펜타오스 생성 아밀라아제 및 말토펜타오스의 생산방법
AU2004229313B2 (en) * 2003-03-06 2010-08-19 Basf Enzymes Llc Amylases, nucleic acids encoding them and methods for making and using them
ATE513917T1 (de) 2003-11-06 2011-07-15 Genencor Int Bakterielle expression von proteaseinhibitoren und varianten davon
US8703459B2 (en) 2003-12-05 2014-04-22 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Catalytic domains of beta(1,4)-galactosyltransferase I having altered metal ion specificity
CN1938422A (zh) 2004-04-08 2007-03-28 金克克国际有限公司 突变体α－淀粉酶
CA2593920A1 (en) * 2004-12-23 2006-06-29 Novozymes A/S Alpha-amylase variants

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