BRPI1009346A2 - metodo de formacao de imagem optica in vivo das margens tumorais de um tumor, agente de contraste, composicao farmaceutica, e, kit - Google Patents

metodo de formacao de imagem optica in vivo das margens tumorais de um tumor, agente de contraste, composicao farmaceutica, e, kit

Info

Publication number
BRPI1009346A2
BRPI1009346A2 BRPI1009346A BRPI1009346A BRPI1009346A2 BR PI1009346 A2 BRPI1009346 A2 BR PI1009346A2 BR PI1009346 A BRPI1009346 A BR PI1009346A BR PI1009346 A BRPI1009346 A BR PI1009346A BR PI1009346 A2 BRPI1009346 A2 BR PI1009346A2
Authority
BR
Brazil
Prior art keywords
tumor
kit
optical
pharmaceutical composition
contrast agent
Prior art date
Application number
BRPI1009346A
Other languages
English (en)
Inventor
Sood Anup
Duh-Lan Lee Brian
William Castle Jason
Michael Fish Kenneth
Anne Staples Natalie
Lee Carter Randall
Original Assignee
General Eletric Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Eletric Company filed Critical General Eletric Company
Publication of BRPI1009346A2 publication Critical patent/BRPI1009346A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0054—Macromolecular compounds, i.e. oligomers, polymers, dendrimers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
BRPI1009346A 2009-03-19 2010-03-19 metodo de formacao de imagem optica in vivo das margens tumorais de um tumor, agente de contraste, composicao farmaceutica, e, kit BRPI1009346A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16153509P 2009-03-19 2009-03-19
PCT/EP2010/053619 WO2010106169A1 (en) 2009-03-19 2010-03-19 Optical imaging agents

Publications (1)

Publication Number Publication Date
BRPI1009346A2 true BRPI1009346A2 (pt) 2017-05-30

Family

ID=42331047

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1009346A BRPI1009346A2 (pt) 2009-03-19 2010-03-19 metodo de formacao de imagem optica in vivo das margens tumorais de um tumor, agente de contraste, composicao farmaceutica, e, kit

Country Status (11)

Country Link
US (1) US20120114563A1 (pt)
EP (1) EP2413976A1 (pt)
JP (1) JP2012520856A (pt)
KR (1) KR20110138246A (pt)
CN (1) CN102438659A (pt)
AU (1) AU2010224789A1 (pt)
BR (1) BRPI1009346A2 (pt)
CA (1) CA2755770A1 (pt)
MX (1) MX2011009808A (pt)
RU (1) RU2011138096A (pt)
WO (1) WO2010106169A1 (pt)

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GB201015806D0 (en) 2010-09-21 2010-10-27 Ge Healthcare As Vascular imaging agents
WO2012088007A1 (en) 2010-12-21 2012-06-28 Pierce Biotechnology, Inc. Fluorescent compounds
US8889884B1 (en) 2011-07-14 2014-11-18 Pierce Biotechnology, Inc. Phosphine derivatives of fluorescent compounds
ES2683377T3 (es) 2011-07-29 2018-09-26 Avelas Biosciences, Inc. Moléculas de suministro selectivo y métodos de uso
US9249307B2 (en) 2011-08-16 2016-02-02 Pierce Biotechnology, Inc. Benzocyanine compounds
GB201116733D0 (en) 2011-09-28 2011-11-09 Ge Healthcare As Peptide margin imaging agents
US9751868B2 (en) 2012-02-28 2017-09-05 Pierce Biotechnology, Inc. Benzocyanine compounds
EP2804860B1 (en) 2012-03-02 2016-06-15 Pierce Biotechnology, Inc. Indole derivatives as labeling dye for biomolecule
WO2014013730A1 (en) * 2012-07-20 2014-01-23 Canon Kabushiki Kaisha Compound and photoacoustic imaging contrast medium containing the compound
JP6288970B2 (ja) * 2012-07-20 2018-03-07 キヤノン株式会社 化合物、および、前記化合物を有する光音響イメージング用造影剤
CN104540819B (zh) 2012-08-28 2019-04-19 皮尔斯生物科技有限公司 苯并吡喃鎓化合物
US20150258217A1 (en) * 2012-10-04 2015-09-17 The General Hospital Corporation Methods of Synthesizing and Using Peg-Like Fluorochromes
CN104956201B (zh) * 2013-01-28 2018-08-28 国立研究开发法人科学技术振兴机构 组织透明化方法、组织透明化试剂及组织观察方法
JP6508781B2 (ja) * 2013-01-30 2019-05-08 アベラス バイオサイエンシーズ，インク． 選択的な送達分子及びその使用方法
FR3001463B1 (fr) * 2013-01-31 2015-02-20 Commissariat Energie Atomique Particules luminescentes de carbone, procede de preparation et utilisation
EP3052136A4 (en) * 2013-10-02 2017-06-21 University of Massachusetts Surface functionalized, host-guest polymer nano-assemblies and methods thereof
US9416276B2 (en) 2013-11-07 2016-08-16 Canon Kabushiki Kaisha Method for producing contrast agent
US10245329B2 (en) * 2014-09-08 2019-04-02 Canon Kabushiki Kaisha Composition having dye and conjugate of polyethyleneglycol and additive and contrast agent for photoacoustic imaging having the same
WO2016060277A1 (en) 2014-10-16 2016-04-21 Canon Kabushiki Kaisha Polymer, and contrast agent for photoacoustic imaging, including the polymer
EP3188764B1 (en) 2014-10-24 2023-08-23 Canon Kabushiki Kaisha Polymer and contrast agent for photoacoustic imaging including the polymer
JP6700750B2 (ja) 2014-12-09 2020-05-27 キヤノン株式会社 化合物、および、前記化合物を有する光学イメージング用造影剤
EP3233133B1 (en) * 2014-12-19 2020-09-02 Bracco Imaging S.p.A Intra-operative imaging
US10383957B2 (en) 2015-01-06 2019-08-20 Anthony H. de Haas Near-infrared fluorescent surgical dye markers
JP2017002000A (ja) * 2015-06-12 2017-01-05 キヤノン株式会社 化合物又はその薬学的に受容可能な塩、及び、前記化合物又はその薬学的に受容可能な塩を有する光音響イメージング用造影剤。
WO2017057653A1 (en) 2015-09-30 2017-04-06 Canon Kabushiki Kaisha Conjugate of polysarcosine and nir contrast agent for photoacoustic imaging
JP6789636B2 (ja) 2015-09-30 2020-11-25 キヤノン株式会社 重合体、前記重合体を有する光音響イメージング用造影剤
CN105688230B (zh) * 2016-02-02 2018-12-11 史春梦 七甲川吲哚花菁染料-聚乙二醇-叶酸复合物及制备方法和应用
CN109054013A (zh) * 2018-08-22 2018-12-21 东北大学 一种经修饰的吲哚菁绿及其制备方法
CN109738387A (zh) * 2018-12-29 2019-05-10 佛山科学技术学院 一种基于吲哚箐绿的光学相干层析成像方法和装置
WO2025197935A1 (ja) * 2024-03-19 2025-09-25 国立大学法人 東京大学 薬物－ポリマー複合体、医薬組成物、および薬物送達用ポリマー

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622685A (en) 1990-05-30 1997-04-22 Deutches Krebsforchunszentrum Stiftung Des Offentlichen Rechts Polyether-substituted porphyrin anti-tumor agents
DE4445065A1 (de) 1994-12-07 1996-06-13 Diagnostikforschung Inst Verfahren zur In-vivo-Diagnostik mittels NIR-Strahlung
AU7221398A (en) 1997-04-29 1998-11-24 Nycomed Imaging As Method of demarcating tissue
GB2337523A (en) * 1998-04-29 1999-11-24 Nycomed Imaging As Light imaging contrast agents
US20100143258A1 (en) * 2008-12-05 2010-06-10 General Electric Company Tumor margin imaging agents

Also Published As

Publication number Publication date
US20120114563A1 (en) 2012-05-10
WO2010106169A1 (en) 2010-09-23
EP2413976A1 (en) 2012-02-08
CN102438659A (zh) 2012-05-02
JP2012520856A (ja) 2012-09-10
CA2755770A1 (en) 2010-09-23
AU2010224789A1 (en) 2011-10-06
MX2011009808A (es) 2011-09-30
KR20110138246A (ko) 2011-12-26
RU2011138096A (ru) 2013-04-27

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]