BRPI1009442A2 - uso de lactóis rosuvastatina como medicamentos - Google Patents

uso de lactóis rosuvastatina como medicamentos

Info

Publication number: BRPI1009442A2
Authority: BR; Brazil
Prior art keywords: medicines; lactols; rosuvastatin; rosuvastatin lactols
Prior art date: 2009-03-10

Application number

BRPI1009442A

Other languages

English (en)

Inventor

Derek Lindsay

Peter Jackson

Original Assignee

Redx Pharma Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-03-10

Filing date

2010-03-10

Publication date

2016-03-01

2010-03-10 Application filed by Redx Pharma Ltd filed Critical Redx Pharma Ltd

2016-03-01 Publication of BRPI1009442A2 publication Critical patent/BRPI1009442A2/pt

Links

229940079593 drug Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
BPRHUIZQVSMCRT-VEUZHWNKSA-N rosuvastatin Chemical compound CC(C)C1=NC(N(C)S(C)(=O)=O)=NC(C=2C=CC(F)=CC=2)=C1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O BPRHUIZQVSMCRT-VEUZHWNKSA-N 0.000 title 1
229960000672 rosuvastatin Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Cardiology (AREA)
Hematology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Ophthalmology & Optometry (AREA)
Emergency Medicine (AREA)
Hospice & Palliative Care (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pyrane Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

BRPI1009442A 2009-03-10 2010-03-10 uso de lactóis rosuvastatina como medicamentos BRPI1009442A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0904100.5A GB0904100D0 (en)	2009-03-10	2009-03-10	Use of rosuvastatin lactols as medicaments
PCT/GB2010/050409 WO2010103320A1 (en)	2009-03-10	2010-03-10	Use of rosuvastatin lactols as medicaments

Publications (1)

Publication Number	Publication Date
BRPI1009442A2 true BRPI1009442A2 (pt)	2016-03-01

Family

ID=40600801

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI1009442A BRPI1009442A2 (pt)	2009-03-10	2010-03-10	uso de lactóis rosuvastatina como medicamentos

Country Status (19)

Country	Link
US (2)	US20120004408A1 (pt)
EP (1)	EP2405972B1 (pt)
JP (1)	JP5765739B2 (pt)
KR (1)	KR20110128194A (pt)
CN (1)	CN102387837B (pt)
AU (1)	AU2010222658B2 (pt)
BR (1)	BRPI1009442A2 (pt)
CA (1)	CA2754825A1 (pt)
DK (1)	DK2405972T3 (pt)
EA (1)	EA022783B1 (pt)
ES (1)	ES2409406T3 (pt)
GB (1)	GB0904100D0 (pt)
IL (1)	IL215039A (pt)
MX (1)	MX2011009456A (pt)
NZ (1)	NZ595116A (pt)
PL (1)	PL2405972T3 (pt)
PT (1)	PT2405972E (pt)
WO (1)	WO2010103320A1 (pt)
ZA (1)	ZA201107053B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0904100D0 (en)	2009-03-10	2009-04-22	Bradford Pharma Ltd	Use of rosuvastatin lactols as medicaments
GB0904104D0 (en)	2009-03-10	2009-04-22	Bradford Pharma Ltd	Atorvastatin and rosuvastatin derivatives
GB0904102D0 (en) *	2009-03-10	2009-04-22	Bradford Pharma Ltd	Use of atorvastatin lactols as medicaments
WO2014045294A1 (en) *	2012-09-20	2014-03-27	Inogent Laboratories Private Limited	A novel process for the preparation of rosuvastatin calcium using novel intermediates
KR20160074540A (ko)	2013-10-17	2016-06-28	다우 아그로사이언시즈 엘엘씨	살충성 화합물의 제조 방법
CN105636445B (zh)	2013-10-17	2018-12-07	美国陶氏益农公司	制备杀虫化合物的方法
MX2016004942A (es)	2013-10-17	2016-06-28	Dow Agrosciences Llc	Procesos para la preparacion de compuestos plaguicidas.
CN105636442B (zh)	2013-10-17	2018-04-27	美国陶氏益农公司	制备杀虫化合物的方法
AU2015217221A1 (en)	2014-02-13	2016-08-11	Ligand Pharmaceuticals, Inc.	Prodrug compounds and their uses
CN104293849A (zh) *	2014-06-10	2015-01-21	常州金隆生物医药有限公司	一种瑞舒伐他汀钙的制备方法
JP2017523163A (ja)	2014-07-31	2017-08-17	ダウアグロサイエンシィズエルエルシー	３−（３−クロロ−１ｈ−ピラゾール−１−イル）ピリジンの製造方法
US10467988B2 (en) *	2015-02-25	2019-11-05	Rockwell Automation Asia Pacific Business Center Pte. Ltd.	Amalgamated alphanumeric character display system and method
PL124682U1 (pl) *	2015-12-16	2017-06-19	Ewa Edyta Bujak	Zestaw rehabilitacyjny układanki sensorycznej, zwłaszcza dla dzieci z zaburzeniami psychomotorycznymi
CA3087932A1 (en) *	2018-01-09	2019-07-18	Ligand Pharmaceuticals, Inc.	Acetal compounds and therapeutic uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4681893A (en)	1986-05-30	1987-07-21	Warner-Lambert Company	Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
FI90236C (fi)	1987-07-10	1994-01-10	Hoechst Ag	Menetelmä terapeuttisesti käyttökelpoisten 3-desmetyylimevalonihappojohdannaisten valmistamiseksi
FI94339C (fi)	1989-07-21	1995-08-25	Warner Lambert Co	Menetelmä farmaseuttisesti käyttökelpoisen /R-(R,R)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
JP2648897B2 (ja)	1991-07-01	1997-09-03	塩野義製薬株式会社	ピリミジン誘導体
EP2522656A3 (en) *	2003-07-25	2013-03-20	Redx Pharma Limited	Process and Intermediate Compounds Useful in the Preparation of Statins, Particularly Atorvastatin
GB0406757D0 (en) *	2004-03-26	2004-04-28	Avecia Ltd	Process and compounds
DE102005022284A1 (de) *	2005-05-13	2006-11-23	Ratiopharm Gmbh	Verfahren zur Herstellung von Statinen
EP1834944A1 (en) *	2006-03-17	2007-09-19	Ratiopharm GmbH	Process for preparing C7 intermediates and their use in the preparation on N-substituted pyrrole derivatives
GB0904104D0 (en)	2009-03-10	2009-04-22	Bradford Pharma Ltd	Atorvastatin and rosuvastatin derivatives
GB0904100D0 (en)	2009-03-10	2009-04-22	Bradford Pharma Ltd	Use of rosuvastatin lactols as medicaments
GB0904102D0 (en)	2009-03-10	2009-04-22	Bradford Pharma Ltd	Use of atorvastatin lactols as medicaments

2009
- 2009-03-10 GB GBGB0904100.5A patent/GB0904100D0/en not_active Ceased
2010
- 2010-03-10 US US13/255,705 patent/US20120004408A1/en not_active Abandoned
- 2010-03-10 PL PL10709041T patent/PL2405972T3/pl unknown
- 2010-03-10 ES ES10709041T patent/ES2409406T3/es active Active
- 2010-03-10 DK DK10709041.7T patent/DK2405972T3/da active
- 2010-03-10 PT PT107090417T patent/PT2405972E/pt unknown
- 2010-03-10 MX MX2011009456A patent/MX2011009456A/es active IP Right Grant
- 2010-03-10 EA EA201101194A patent/EA022783B1/ru not_active IP Right Cessation
- 2010-03-10 NZ NZ595116A patent/NZ595116A/xx not_active IP Right Cessation
- 2010-03-10 CA CA2754825A patent/CA2754825A1/en not_active Abandoned
- 2010-03-10 KR KR1020117023589A patent/KR20110128194A/ko not_active Ceased
- 2010-03-10 EP EP10709041A patent/EP2405972B1/en not_active Not-in-force
- 2010-03-10 CN CN201080016166.2A patent/CN102387837B/zh not_active Expired - Fee Related
- 2010-03-10 AU AU2010222658A patent/AU2010222658B2/en not_active Ceased
- 2010-03-10 JP JP2011553527A patent/JP5765739B2/ja not_active Expired - Fee Related
- 2010-03-10 BR BRPI1009442A patent/BRPI1009442A2/pt not_active IP Right Cessation
- 2010-03-10 WO PCT/GB2010/050409 patent/WO2010103320A1/en not_active Ceased
2011
- 2011-09-08 IL IL215039A patent/IL215039A/en not_active IP Right Cessation
- 2011-09-27 ZA ZA2011/07053A patent/ZA201107053B/en unknown
2013
- 2013-09-17 US US14/029,056 patent/US9102656B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP2405972A1 (en)	2012-01-18
CA2754825A1 (en)	2010-09-16
ES2409406T3 (es)	2013-06-26
GB0904100D0 (en)	2009-04-22
IL215039A (en)	2014-12-31
EP2405972B1 (en)	2013-03-06
CN102387837A (zh)	2012-03-21
AU2010222658A1 (en)	2011-09-29
AU2010222658B2 (en)	2014-10-02
EA201101194A1 (ru)	2012-04-30
WO2010103320A1 (en)	2010-09-16
US9102656B2 (en)	2015-08-11
PL2405972T3 (pl)	2013-10-31
EA022783B1 (ru)	2016-03-31
MX2011009456A (es)	2012-04-10
CN102387837B (zh)	2015-11-25
KR20110128194A (ko)	2011-11-28
JP2012520281A (ja)	2012-09-06
JP5765739B2 (ja)	2015-08-19
ZA201107053B (en)	2014-03-26
PT2405972E (pt)	2013-06-05
IL215039A0 (en)	2011-11-30
US20120004408A1 (en)	2012-01-05
US20140018381A1 (en)	2014-01-16
NZ595116A (en)	2013-02-22
DK2405972T3 (da)	2013-06-10

Legal Events

Date	Code	Title	Description
2016-12-06	B25D	Requested change of name of applicant approved	Owner name: REDX PHARMA PLC (GB)
2017-01-17	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 7A ANUIDADE.
2017-05-23	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
2021-06-01	B350	Update of information on the portal [chapter 15.35 patent gazette]

Publication	Publication Date	Title
BRPI1009442A2 (pt)	2016-03-01	uso de lactóis rosuvastatina como medicamentos
BR112013016030A2 (pt)	2018-07-24	compostos e seu uso como inibidores de bace
BR112013002845A2 (pt)	2016-06-07	combinação de susbtâncias ativas
BRPI1014708A2 (pt)	2016-04-12	dihidropirimidinonas para uso como inibidores de bace2
BR112012021065A2 (pt)	2016-05-17	artigo de uso descartável
BR112012002331A2 (pt)	2019-09-24	composição antiviral, composição farmacêutica e uso de quantidade efetiva de composição farmacêutica
BR112012004843A2 (pt)	2019-09-24	compostos como moduladores de tirosina cinase
EP2520259A4 (en)	2013-10-30	DIAPER
BRPI1006519A2 (pt)	2016-08-09	formulação de anticorpos
DK2246017T3 (da)	2020-02-24	Absorberende genstand
SMT201400069B (it)	2014-07-07	Formulazione farmaceutica
HRP20180429T1 (hr)	2019-01-11	Raspršivač
BRPI1008744A2 (pt)	2016-03-15	hidrotratamento de caboidratos
BR112012005400A2 (pt)	2016-04-05	derivados do tipo éter de heteroarilas bicíclicas
UY33155A (es)	2011-07-29	Indolil-piperidinil bencilaminas como inhibidores de beta-triptasa
EP2433616A4 (en)	2015-06-17	COSMETIC PREPARATION
EP2498298A4 (en)	2013-11-06	SOLAR CELL MODULE
BRPI1011036A2 (pt)	2017-09-26	uso
EP2560655A4 (en)	2013-09-04	SUBSTITUTED PYRIMIDINES
BRPI0920502A2 (pt)	2015-12-22	compostos cicloundecadepsipeptídeos e seu uso como medicamento
ES2439793T9 (es)	2016-03-10	Compuestos de pirimidina, su uso como inhibidores de la mTOR quinasa y de la PI3 quinasa, y su síntesis
BR112012010524A2 (pt)	2017-12-12	compostos derivados de quinazolina
BRPI0909840A2 (pt)	2015-07-28	Uso de 4-tio-2-deoxinucleosídios
BR112013009640A2 (pt)	2016-07-12	derivados de tetrahidroquinolina usados como ativadores de ampk
CR20120395A (es)	2012-08-30	Uso farmacéutico de compuestos multicíclicos como agentes anti-síndrome de inmunodeficiencia adquirida