DK2405972T3 - Anvendelse af rosuvastatin lactoler som medikamenter - Google Patents

Anvendelse af rosuvastatin lactoler som medikamenter

Info

Publication number: DK2405972T3
Authority: DK; Denmark
Prior art keywords: medicines; lactols; rosuvastatin; rosuvastatin lactols
Prior art date: 2009-03-10

Application number

DK10709041.7T

Other languages

English (en)

Inventor

Derek Lindsay

Peter Jackson

Original Assignee

Redx Pharma Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-03-10

Filing date

2010-03-10

Publication date

2013-06-10

2010-03-10 Application filed by Redx Pharma Ltd filed Critical Redx Pharma Ltd

2013-06-10 Application granted granted Critical

2013-06-10 Publication of DK2405972T3 publication Critical patent/DK2405972T3/da

Links

239000003814 drug Substances 0.000 title 1
BPRHUIZQVSMCRT-VEUZHWNKSA-N rosuvastatin Chemical compound CC(C)C1=NC(N(C)S(C)(=O)=O)=NC(C=2C=CC(F)=CC=2)=C1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O BPRHUIZQVSMCRT-VEUZHWNKSA-N 0.000 title 1
229960000672 rosuvastatin Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Hematology (AREA)
Neurology (AREA)
Obesity (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Ophthalmology & Optometry (AREA)
Emergency Medicine (AREA)
Hospice & Palliative Care (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pyrane Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK10709041.7T 2009-03-10 2010-03-10 Anvendelse af rosuvastatin lactoler som medikamenter DK2405972T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0904100.5A GB0904100D0 (en)	2009-03-10	2009-03-10	Use of rosuvastatin lactols as medicaments
PCT/GB2010/050409 WO2010103320A1 (en)	2009-03-10	2010-03-10	Use of rosuvastatin lactols as medicaments

Publications (1)

Publication Number	Publication Date
DK2405972T3 true DK2405972T3 (da)	2013-06-10

Family

ID=40600801

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK10709041.7T DK2405972T3 (da)	2009-03-10	2010-03-10	Anvendelse af rosuvastatin lactoler som medikamenter

Country Status (19)

Country	Link
US (2)	US20120004408A1 (da)
EP (1)	EP2405972B1 (da)
JP (1)	JP5765739B2 (da)
KR (1)	KR20110128194A (da)
CN (1)	CN102387837B (da)
AU (1)	AU2010222658B2 (da)
BR (1)	BRPI1009442A2 (da)
CA (1)	CA2754825A1 (da)
DK (1)	DK2405972T3 (da)
EA (1)	EA022783B1 (da)
ES (1)	ES2409406T3 (da)
GB (1)	GB0904100D0 (da)
IL (1)	IL215039A (da)
MX (1)	MX2011009456A (da)
NZ (1)	NZ595116A (da)
PL (1)	PL2405972T3 (da)
PT (1)	PT2405972E (da)
WO (1)	WO2010103320A1 (da)
ZA (1)	ZA201107053B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0904100D0 (en)	2009-03-10	2009-04-22	Bradford Pharma Ltd	Use of rosuvastatin lactols as medicaments
GB0904102D0 (en) *	2009-03-10	2009-04-22	Bradford Pharma Ltd	Use of atorvastatin lactols as medicaments
GB0904104D0 (en)	2009-03-10	2009-04-22	Bradford Pharma Ltd	Atorvastatin and rosuvastatin derivatives
WO2014045294A1 (en) *	2012-09-20	2014-03-27	Inogent Laboratories Private Limited	A novel process for the preparation of rosuvastatin calcium using novel intermediates
WO2015058024A1 (en)	2013-10-17	2015-04-23	Dow Agrosciences Llc	Processes for the preparation of pesticidal compounds
US9174962B2 (en)	2013-10-17	2015-11-03	Dow Agrosciences Llc	Processes for the preparation of pesticidal compounds
WO2015058022A1 (en)	2013-10-17	2015-04-23	Dow Agrosciences Llc	Processes for the preparation of pesticidal compounds
WO2015058028A1 (en)	2013-10-17	2015-04-23	Dow Agrosciences Llc	Processes for the preparation of pesticidal compounds
AU2015217221A1 (en)	2014-02-13	2016-08-11	Ligand Pharmaceuticals, Inc.	Prodrug compounds and their uses
CN104293849A (zh) *	2014-06-10	2015-01-21	常州金隆生物医药有限公司	一种瑞舒伐他汀钙的制备方法
EP3174856A4 (en)	2014-07-31	2018-01-10	Dow AgroSciences LLC	Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
US10467988B2 (en) *	2015-02-25	2019-11-05	Rockwell Automation Asia Pacific Business Center Pte. Ltd.	Amalgamated alphanumeric character display system and method
PL124682U1 (pl) *	2015-12-16	2017-06-19	Ewa Edyta Bujak	Zestaw rehabilitacyjny układanki sensorycznej, zwłaszcza dla dzieci z zaburzeniami psychomotorycznymi
CA3087932A1 (en)	2018-01-09	2019-07-18	Ligand Pharmaceuticals, Inc.	Acetal compounds and therapeutic uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4681893A (en)	1986-05-30	1987-07-21	Warner-Lambert Company	Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
PT87929B (pt) *	1987-07-10	1995-03-01	Hoechst Ag	Processo para a preparacao de derivados de acido 3-desmetil-mevalonico e de composicoes farmaceuticas que os contem
FI94339C (fi)	1989-07-21	1995-08-25	Warner Lambert Co	Menetelmä farmaseuttisesti käyttökelpoisen /R-(R,R)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
JP2648897B2 (ja)	1991-07-01	1997-09-03	塩野義製薬株式会社	ピリミジン誘導体
CA2530163C (en) *	2003-07-25	2012-10-02	Avecia Pharmaceuticals Limited	Process and intermediate compounds useful in the preparation of statins, particularly atorvastatin
GB0406757D0 (en) *	2004-03-26	2004-04-28	Avecia Ltd	Process and compounds
DE102005022284A1 (de) *	2005-05-13	2006-11-23	Ratiopharm Gmbh	Verfahren zur Herstellung von Statinen
EP1834944A1 (en) *	2006-03-17	2007-09-19	Ratiopharm GmbH	Process for preparing C7 intermediates and their use in the preparation on N-substituted pyrrole derivatives
GB0904100D0 (en)	2009-03-10	2009-04-22	Bradford Pharma Ltd	Use of rosuvastatin lactols as medicaments
GB0904104D0 (en) *	2009-03-10	2009-04-22	Bradford Pharma Ltd	Atorvastatin and rosuvastatin derivatives
GB0904102D0 (en)	2009-03-10	2009-04-22	Bradford Pharma Ltd	Use of atorvastatin lactols as medicaments

2009
- 2009-03-10 GB GBGB0904100.5A patent/GB0904100D0/en not_active Ceased
2010
- 2010-03-10 PT PT107090417T patent/PT2405972E/pt unknown
- 2010-03-10 EP EP10709041A patent/EP2405972B1/en not_active Not-in-force
- 2010-03-10 PL PL10709041T patent/PL2405972T3/pl unknown
- 2010-03-10 EA EA201101194A patent/EA022783B1/ru not_active IP Right Cessation
- 2010-03-10 WO PCT/GB2010/050409 patent/WO2010103320A1/en not_active Ceased
- 2010-03-10 KR KR1020117023589A patent/KR20110128194A/ko not_active Ceased
- 2010-03-10 JP JP2011553527A patent/JP5765739B2/ja not_active Expired - Fee Related
- 2010-03-10 AU AU2010222658A patent/AU2010222658B2/en not_active Ceased
- 2010-03-10 CN CN201080016166.2A patent/CN102387837B/zh not_active Expired - Fee Related
- 2010-03-10 MX MX2011009456A patent/MX2011009456A/es active IP Right Grant
- 2010-03-10 CA CA2754825A patent/CA2754825A1/en not_active Abandoned
- 2010-03-10 DK DK10709041.7T patent/DK2405972T3/da active
- 2010-03-10 US US13/255,705 patent/US20120004408A1/en not_active Abandoned
- 2010-03-10 NZ NZ595116A patent/NZ595116A/xx not_active IP Right Cessation
- 2010-03-10 ES ES10709041T patent/ES2409406T3/es active Active
- 2010-03-10 BR BRPI1009442A patent/BRPI1009442A2/pt not_active IP Right Cessation
2011
- 2011-09-08 IL IL215039A patent/IL215039A/en not_active IP Right Cessation
- 2011-09-27 ZA ZA2011/07053A patent/ZA201107053B/en unknown
2013
- 2013-09-17 US US14/029,056 patent/US9102656B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CN102387837A (zh)	2012-03-21
BRPI1009442A2 (pt)	2016-03-01
NZ595116A (en)	2013-02-22
ES2409406T3 (es)	2013-06-26
JP5765739B2 (ja)	2015-08-19
CN102387837B (zh)	2015-11-25
JP2012520281A (ja)	2012-09-06
IL215039A (en)	2014-12-31
MX2011009456A (es)	2012-04-10
EP2405972B1 (en)	2013-03-06
KR20110128194A (ko)	2011-11-28
AU2010222658A1 (en)	2011-09-29
EP2405972A1 (en)	2012-01-18
ZA201107053B (en)	2014-03-26
PL2405972T3 (pl)	2013-10-31
US20140018381A1 (en)	2014-01-16
EA201101194A1 (ru)	2012-04-30
IL215039A0 (en)	2011-11-30
WO2010103320A1 (en)	2010-09-16
US20120004408A1 (en)	2012-01-05
CA2754825A1 (en)	2010-09-16
US9102656B2 (en)	2015-08-11
PT2405972E (pt)	2013-06-05
AU2010222658B2 (en)	2014-10-02
EA022783B1 (ru)	2016-03-31
GB0904100D0 (en)	2009-04-22

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