BRPI1010647A2 - combinação de (a) um inibidor de fosfoinositídeo 3-quinase e (b) um composto antidiabético para uso no tratamento de doenças proliferativas - Google Patents
combinação de (a) um inibidor de fosfoinositídeo 3-quinase e (b) um composto antidiabético para uso no tratamento de doenças proliferativasInfo
- Publication number
- BRPI1010647A2 BRPI1010647A2 BRPI1010647A BRPI1010647A BRPI1010647A2 BR PI1010647 A2 BRPI1010647 A2 BR PI1010647A2 BR PI1010647 A BRPI1010647 A BR PI1010647A BR PI1010647 A BRPI1010647 A BR PI1010647A BR PI1010647 A2 BRPI1010647 A2 BR PI1010647A2
- Authority
- BR
- Brazil
- Prior art keywords
- phosphoinositide
- treatment
- combination
- kinase inhibitor
- proliferative diseases
- Prior art date
Links
- 230000003178 anti-diabetic effect Effects 0.000 title 1
- 239000003472 antidiabetic agent Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 239000002935 phosphatidylinositol 3 kinase inhibitor Substances 0.000 title 1
- 229940043441 phosphoinositide 3-kinase inhibitor Drugs 0.000 title 1
- 230000002062 proliferating effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
- A23L2/66—Proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/20—Milk; Whey; Colostrum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pediatric Medicine (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09159964A EP2251029A1 (en) | 2009-05-12 | 2009-05-12 | Lactoferrin and gut neuronal health in adults and/or elderly |
| PCT/EP2010/056238 WO2010130644A1 (en) | 2009-05-12 | 2010-05-07 | Combination of (a) a phosphoinositide 3-kinase inhibitor and (b) an antidiabetic compound for use in the treatment of proliferative diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1010647A2 true BRPI1010647A2 (pt) | 2016-03-15 |
Family
ID=41110391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1010647A BRPI1010647A2 (pt) | 2009-05-12 | 2010-05-07 | combinação de (a) um inibidor de fosfoinositídeo 3-quinase e (b) um composto antidiabético para uso no tratamento de doenças proliferativas |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8592369B2 (pt) |
| EP (2) | EP2251029A1 (pt) |
| JP (2) | JP2012526747A (pt) |
| CN (1) | CN102458449B (pt) |
| BR (1) | BRPI1010647A2 (pt) |
| WO (1) | WO2010130644A1 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2251031A1 (en) * | 2009-05-12 | 2010-11-17 | Nestec S.A. | Lactoferrin and neuronal health and development in the infant gut |
| PL2594282T3 (pl) * | 2011-11-21 | 2015-01-30 | Nestec Sa | Laktoferyna i istota biała |
| MX2016001225A (es) * | 2013-09-02 | 2016-05-24 | Nestec Sa | Lactoferrina y memoria y velocidad de aprendizaje en niños. |
| US11197917B2 (en) | 2017-12-01 | 2021-12-14 | ByHeart, Inc. | Formulations for nutritional support in subjects in need thereof |
| CN110839698A (zh) * | 2019-11-29 | 2020-02-28 | 内蒙古伊利实业集团股份有限公司 | 一种组合物及其食品用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4977137B1 (en) * | 1987-06-03 | 1994-06-28 | Baylor College Medicine | Lactoferrin as a dietary ingredient promoting the growth of the gastrointestinal tract |
| ATE84680T1 (de) | 1987-12-23 | 1993-02-15 | Nestle Sa | Verfahren zur herstellung eines molkeeiweisshydrolysates und eines hypoallergenen nahrungsmittels. |
| JPH0779684B2 (ja) * | 1989-02-27 | 1995-08-30 | 森永乳業株式会社 | ビフィズス菌増殖促進組成物 |
| JP2660908B2 (ja) * | 1995-02-24 | 1997-10-08 | 森永乳業株式会社 | ビフィズス菌増殖促進性及び生残性が良好なヨーグルト |
| EP0880902A1 (fr) | 1997-05-27 | 1998-12-02 | Nestlé Produkte AG | Procédé de traitement d'une matiére première lactosérique |
| US6258383B1 (en) * | 1998-08-14 | 2001-07-10 | Lactoferrin Products Company | Dietary supplement combining colostrum and lactoferrin in a mucosal delivery format |
| CA2371696C (en) | 1999-04-29 | 2005-11-15 | Societe Des Produits Nestle S.A. | Composition for an infant formula having a low threonine content |
| JP4452569B2 (ja) * | 2004-06-29 | 2010-04-21 | 有限会社フードデザイン健康研究所 | 桃の花及びラクトフェリンを主成分とする食品 |
| US20060068022A1 (en) * | 2004-09-29 | 2006-03-30 | Playford Raymond J | Bioactive agent compositions for repair of cell injuries |
| US20070036873A1 (en) * | 2005-07-27 | 2007-02-15 | Shibnath Ghosal | Method of treatment or management of stress |
| CN101472612B (zh) * | 2006-06-14 | 2011-06-08 | 纽崔西亚公司 | 包含甘氨酸和乳铁蛋白的抗炎组合物及其应用 |
| ITRM20060434A1 (it) * | 2006-08-07 | 2008-02-08 | Pietro Raimondi | Prodotto da somministrare all organismo umano per isuoi effetti protettivi e curativi a base di latte di bufala autorricchito di lattoferrina oppure di lattoferrina tal quale ottenuto attraverso processi separativi di membrana |
-
2009
- 2009-05-12 EP EP09159964A patent/EP2251029A1/en not_active Withdrawn
-
2010
- 2010-05-07 WO PCT/EP2010/056238 patent/WO2010130644A1/en not_active Ceased
- 2010-05-07 JP JP2012510226A patent/JP2012526747A/ja active Pending
- 2010-05-07 EP EP10717651A patent/EP2429570A1/en not_active Withdrawn
- 2010-05-07 CN CN201080031296.3A patent/CN102458449B/zh active Active
- 2010-05-07 BR BRPI1010647A patent/BRPI1010647A2/pt not_active IP Right Cessation
- 2010-05-07 US US13/319,656 patent/US8592369B2/en active Active
-
2013
- 2013-11-06 US US14/073,522 patent/US9095570B2/en active Active
-
2015
- 2015-08-06 JP JP2015156030A patent/JP2016020357A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN102458449B (zh) | 2015-04-08 |
| US9095570B2 (en) | 2015-08-04 |
| WO2010130644A8 (en) | 2011-12-22 |
| JP2012526747A (ja) | 2012-11-01 |
| US20140135262A1 (en) | 2014-05-15 |
| WO2010130644A1 (en) | 2010-11-18 |
| US8592369B2 (en) | 2013-11-26 |
| EP2429570A1 (en) | 2012-03-21 |
| JP2016020357A (ja) | 2016-02-04 |
| EP2251029A1 (en) | 2010-11-17 |
| CN102458449A (zh) | 2012-05-16 |
| US20120270777A1 (en) | 2012-10-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Ipc: A61K 38/40 (2006.01), A23L 2/66 (2006.0 |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 9A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2513 DE 06-03-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |